barrenworts

Epimedium · Accepted scientific name

Scientific literature: Moderate (102 studies) · ★★★☆☆

Barrenworts, scientifically known as Epimedium, is a versatile genus of herbaceous perennials celebrated for both ornamental beauty and therapeutic potential. Renowned in traditional medicine, these resilient plants contain unique bioactive compounds like icariin, which are widely studied for their ability to support bone health and cardiovascular wellness.

Family
Berberidaceae
Native range
Europe
Parts used
Leaf · Flower
Common names
Barrenworts · Fairy Wings · 1 more
Scientific synonyms
Aceranthus · × Bonstedtia · 1 more

Names and Synonyms

Common Names

Scientific Names

Accepted name

Epimedium

Synonyms

Regional and Traditional Names

Spanish:

  • Aceranthus

German:

  • Elfenblumen
  • Sockenblumen
  • Sockenblume
  • Elfenblumen

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. It is categorized within the order Ranunculales and the family Berberidaceae. Finally, it is classified under the specific genus Epimedium.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Ranunculales
Family Berberidaceae
Genus Epimedium

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant, known as Epimedium, exhibits a specific range of occurrence across the northern regions of Europe. It can be found growing naturally throughout the Scandinavian territories, including Denmark, Norway, and Sweden. Additionally, its distribution extends into the eastern parts of the continent to include Finland. The plant's presence is also documented within the islands of Great Britain. Consequently, its geographical footprint is concentrated primarily within these northern European nations.

Region Area
Northern Europe Denmark
Northern Europe Finland
Northern Europe Great Britain
Northern Europe Norway
Northern Europe Sweden
Middle Europe Austria
Middle Europe Belgium
Middle Europe Czechia-Slovakia
Middle Europe Germany
Middle Europe Switzerland

Sources: The World Checklist of Vascular Plants (WCVP)

Plant Parts

Epimedium has 3 reported plant parts identified across 7 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include leaf, flower, stem.

Plant parts reported in Epimedium
Plant part Supporting sources Consensus
Leaf 5 supporting sources ★★★☆☆
Flower 1 supporting sources ★☆☆☆☆
Stem 1 supporting sources ★☆☆☆☆

Leaf

  1. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  2. Plant cell reports
  3. Molecules (Basel, Switzerland)
  4. BMC plant biology
  5. Frontiers in plant science

Flower

  1. Plant cell reports

Stem

  1. Molecules (Basel, Switzerland)

Chemicals

Epimedium has 14 reported phytochemicals identified across 7 scientific publications and several other databases. The most consistently reported chemicals include Icariin, Icaritin, Flavonoids, Flavonoid, As.

Chemicals reported in Epimedium
Chemical Supporting sources Consensus
Icariin 14 supporting sources ★★★★★
Icaritin 5 supporting sources ★★★☆☆
Flavonoids 4 supporting sources ★★☆☆☆
Flavonoid 2 supporting sources ★☆☆☆☆
As 1 supporting sources ★☆☆☆☆
Baohuoside I 1 supporting sources ★☆☆☆☆
CU 1 supporting sources ★☆☆☆☆
Ikarisoside A 1 supporting sources ★☆☆☆☆
Magnoflorine 1 supporting sources ★☆☆☆☆
PB 1 supporting sources ★☆☆☆☆

Icariin

  1. Journal of fish biology
  2. Pharmacology & therapeutics
  3. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  4. Journal of hepatocellular carcinoma
  5. Current topics in medicinal chemistry
View 9 additional sources
  1. Life sciences
  2. Pharmaceuticals (Basel, Switzerland)
  3. American journal of translational research
  4. OncoTargets and therapy
  5. Heliyon
  6. Oncology reports
  7. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  8. Current urology reports
  9. Yao xue xue bao = Acta pharmaceutica Sinica

Icaritin

  1. Pharmacology & therapeutics
  2. Oncology reports
  3. Phytomedicine : international journal of phytotherapy and phytopharmacology
  4. Drug delivery
  5. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Flavonoids

  1. The American journal of Chinese medicine
  2. Pharmaceuticals (Basel, Switzerland)
  3. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  4. Heliyon

Flavonoid

  1. Immunology
  2. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

As

  1. Biological trace element research

Baohuoside I

  1. Yao xue xue bao = Acta pharmaceutica Sinica

CU

  1. Biological trace element research

Ikarisoside A

  1. Biomedical chromatography : BMC

Magnoflorine

  1. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

PB

  1. Biological trace element research

Activities

Epimedium has 8 reported activities identified across 7 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Anticancer, Antidiabetic, Antifatigue, Antiinflammatory.

Activities reported in Epimedium
Activity Supporting sources Consensus
Antioxidant 2 supporting sources ★☆☆☆☆
Anticancer 1 supporting sources ★☆☆☆☆
Antidiabetic 1 supporting sources ★☆☆☆☆
Antifatigue 1 supporting sources ★☆☆☆☆
Antiinflammatory 1 supporting sources ★☆☆☆☆
Antitumor 1 supporting sources ★☆☆☆☆
Aphrodisiac 1 supporting sources ★☆☆☆☆
Osteogenic 1 supporting sources ★☆☆☆☆

Antioxidant

  1. Plants (Basel, Switzerland)
  2. Heliyon

Anticancer

  1. Oncology reports

Antidiabetic

  1. Oncology reports

Antifatigue

  1. Frontiers in pharmacology

Antiinflammatory

  1. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

Antitumor

  1. Drug delivery

Aphrodisiac

  1. Frontiers in veterinary science

Osteogenic

  1. American journal of translational research

Conditions

Epimedium has 22 reported investigations on conditions identified across 7 scientific publications and several other databases. The most consistently reported conditions include osteoporosis, cancer, inflammation, liver cancer, Alzheimer's disease.

Conditions investigated for Epimedium
Condition Supporting sources Consensus
Osteoporosis 8 supporting sources ★★★★☆
Cancer 2 supporting sources ★☆☆☆☆
Inflammation 2 supporting sources ★☆☆☆☆
Liver cancer 2 supporting sources ★☆☆☆☆
Alzheimer's disease 1 supporting sources ★☆☆☆☆
Lung adenocarcinoma 1 supporting sources ★☆☆☆☆
Osteoporosis 1 supporting sources ★☆☆☆☆
Aging 1 supporting sources ★☆☆☆☆
Bone formation 1 supporting sources ★☆☆☆☆
Brain diseases 1 supporting sources ★☆☆☆☆

Osteoporosis

  1. Journal of fish biology
  2. Pharmacology & therapeutics
  3. Current topics in medicinal chemistry
  4. Life sciences
  5. Journal of traditional and complementary medicine
View 3 additional sources
  1. Pharmaceuticals (Basel, Switzerland)
  2. Yao xue xue bao = Acta pharmaceutica Sinica
  3. Journal of ethnopharmacology

Cancer

  1. The American journal of Chinese medicine
  2. Drug delivery

Inflammation

  1. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  2. The American journal of Chinese medicine

Liver cancer

  1. Journal of hepatocellular carcinoma
  2. Molecules (Basel, Switzerland)

Alzheimer's disease

  1. Bioorganic chemistry

Lung adenocarcinoma

  1. OncoTargets and therapy

Osteoporosis

  1. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

Aging

  1. Heliyon

Bone formation

  1. The American journal of Chinese medicine

Brain diseases

  1. Phytotherapy research : PTR

Preparations

Epimedium has 11 reported preparations identified across 7 scientific publications and several other databases. The most consistently reported preparations include EBF, Epimedium extract, Epimedium flavonoid (EF), EtOH extract, Icariin.

Preparations reported for Epimedium
Preparation Supporting sources Consensus
Ebf 1 supporting sources ★☆☆☆☆
Epimedium extract 1 supporting sources ★☆☆☆☆
Epimedium flavonoid (ef) 1 supporting sources ★☆☆☆☆
Etoh extract 1 supporting sources ★☆☆☆☆
Icariin 1 supporting sources ★☆☆☆☆
Tcm herbal extracts 1 supporting sources ★☆☆☆☆
Antioxidant carbon dots (cds) 1 supporting sources ★☆☆☆☆
Aqueous decoction 1 supporting sources ★☆☆☆☆
Cut crude drug 1 supporting sources ★☆☆☆☆
Icaritin 1 supporting sources ★☆☆☆☆

Ebf

  1. Molecules (Basel, Switzerland)

Epimedium extract

  1. Journal of pharmaceutical and biomedical analysis

Epimedium flavonoid (ef)

  1. Immunology

Etoh extract

  1. Yao xue xue bao = Acta pharmaceutica Sinica

Icariin

  1. Oncology reports

Tcm herbal extracts

  1. Frontiers in pharmacology

Antioxidant carbon dots (cds)

  1. Plants (Basel, Switzerland)

Aqueous decoction

  1. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Cut crude drug

  1. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

Icaritin

  1. Oncology reports