Eleutherococcus sessiliflorus
Eleutherococcus sessiliflorus · Accepted scientific name
Scientific literature: Very Sparse (4 studies) · ★☆☆☆☆
Eleutherococcus sessiliflorus is a botanical species of significant interest due to its diverse biological activities, including cytotoxic, anticancer, and antioxidant properties. Research utilizing the plant's leaves and stems has focused on various preparations, such as 30% ethanolic extracts and alcohol extracts, as well as studies involving cotyledonary somatic embryos and embryogenic callus. The chemical profile of this plant is characterized by the presence of bioactive compounds like chiisanoside, chiisanogenin, divaroside, and various flavonoids. These constituents offer therapeutic potential in addressing medical conditions such as anti-oxidative stress, arrhythmia, cardiovascular system issues, and gastric ulcers. Consequently, the plant serves as a vital subject for pharmacological exploration aimed at developing new medicinal treatments.
- Synonyms
- Acanthopanax Seoulensis · Eleutherococcus Seoulensis · 3 more
- Common names
- Not available
- Family
- Araliaceae
- Distribution
- Not available
- Plant Parts
- Leaf · Stem
Classification
Common Names
Eleutherococcus sessiliflorus is a versatile plant known by several distinct names depending on the region and language. It is frequently referred to as the Amur-Fingeraralie or the Stalkless-flowered eleuthero in various botanical circles. In different cultural contexts, you may also encounter it called the Tatarian aralia. The species carries local designations such as the eleuterokok bezstopečný and the kiinanaralehti. These diverse common names highlight the plant's widespread recognition across different geographical areas.
Sources: Catalogue of Life (COL)
Synonyms
Eleutherococcus sessiliflorus is a botanical species that is frequently identified by various taxonomic synonyms in scientific literature. It is often referred to by the names Acanthopanax seoulensis and Acanthopanax sessiliflorus. Furthermore, the plant is classified under the synonym Acanthopanax sessiliflorus var. parviceps. Researchers may also encounter it listed as Eleutherococcus seoulensis in different databases. Finally, the name Eleutherococcus sessiliflorus var. parviceps serves as another recognized synonym for this specific plant.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Eleutherococcus sessiliflorus is a unique botanical specimen that belongs to the vast kingdom Plantae. Within this expansive group, it is classified under the class Equisetopsida. This species is further organized into the order Apiales, showcasing its specific evolutionary placement. It is a prominent member of the genus Eleutherococcus, which helps define its distinct characteristics. Finally, it resides within the Araliaceae family, linking it to a diverse array of related flowering plants.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Apiales |
| Family | Araliaceae |
| Genus | Eleutherococcus |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Eleutherococcus sessiliflorus is a plant species widely distributed across the temperate regions of Asia. Within China, its range extends through North-Central areas, Inner Mongolia, and the Manchuria region. Its presence is also noted in Eastern Asia, specifically throughout Korea. Furthermore, the species can be found in the Russian Far East, particularly within the Amur region. This broad geographic spread highlights the plant's adaptability to diverse temperate environments.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Eleutherococcus sessiliflorus is a self-supporting shrub that maintains a sturdy and independent structure. This plant typically reaches a consistent height of exactly 3.5 meters as it matures. Its growth form is characterized by a woody, shrubby habit that defines its presence in the landscape. Consequently, it provides a predictable vertical element to its natural environment.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Eleutherococcus sessiliflorus has emerged as a significant subject of pharmacological interest due to its diverse range of biological activities. Scientific investigations have demonstrated that the plant possesses potent cytotoxic properties, particularly through the action of 3,4-seco-lupane triterpenoids. These compounds have shown a remarkable ability to inhibit the growth of HepG2 cells, highlighting the plant's potential anticancer activity. Furthermore, comparative studies indicate that the extracts from this species demonstrate enhanced antioxidant properties. Together, these findings suggest that the plant could serve as a valuable resource for the development of new antineoplastic drugs.
Compounds
Eleutherococcus sessiliflorus is a versatile medicinal plant known for its rich chemical profile and diverse bioactive components. Extensive phytochemical studies have identified that the plant contains various flavonoids, which contribute to its significant pharmacological potential. Within its leaves, specific 3,4-seco-lupane triterpene derivatives such as chiisanoside, chiisanogenin, and divaroside have been isolated. Furthermore, research into the production of eleutherosides through bioreactor systems highlights that eleutheroside B is found in particularly high concentrations within germinated embryos. Collectively, these diverse compounds underscore the plant's importance as a valuable source of natural medicinal resources.
Conditions
Eleutherococcus sessiliflorus contains bioactive 3,4-seco-lupane triterpene derivatives that demonstrate significant cytotoxic activity against the B16-F10 cancer cell line. The plant's components also exhibit the ability to treat cisplatin-induced ototoxicity (CIO) by protecting against hearing loss. Furthermore, derivatives from this species can address B-lymphocyte proliferation through various immuno-stimulating properties. Research also indicates that its compounds interact with the HL-7702 normal cell line, showing much lower cytotoxicities compared to their effects on malignant cells. These diverse pharmacological activities highlight the complex therapeutic potential of the plant's chemical constituents.
Preparations
Eleutherococcus sessiliflorus is prepared as 30% ethanolic extracts for studies regarding its biochemical properties. The plant is also prepared as embryogenic callus, which serves as the foundation for establishing suspension cultures. These cultures are utilized to produce cotyledonary somatic embryos for large-scale biomass production in bioreactors. Additionally, researchers have utilized alcohol extract and ethanol extract of the leaves to isolate various triterpene derivatives. These diverse preparation methods allow for both the mass production of medicinal raw materials and the detailed chemical analysis of the species.
Parts used
Eleutherococcus sessiliflorus, also known as Acanthopanax sessiliflorus, is a versatile plant species that offers significant medicinal and nutritional benefits through its various anatomical structures. Research indicates that the leaves of this plant are rich in phytochemicals, providing sedative-hypnotic effects and protective chiisanoside derivatives that can combat oxidative stress. Additionally, the stem serves as a valuable source of bioactive compounds, including oleanane-type saponins and lignans, which exhibit strong antioxidant properties. Studies on the stem bark have even demonstrated cytotoxic potential against certain human breast cancer cell lines. By utilizing both the leaves and stems, researchers aim to expand the functional food and pharmaceutical applications of this highly resourceful woody shrub.