Dysoxylum gotadhora
Dysoxylum gotadhora · Accepted scientific name
Scientific literature: Very Sparse (3 studies) · ★☆☆☆☆
Dysoxylum gotadhora is a medicinal plant that has gained significant scientific attention due to its diverse antibacterial, anticancer, and antileukemic activities. Research indicates that various parts of the plant, specifically the leaves and stems, contain potent bioactive chemicals such as rohitukine, rocaglaol, and schumaniofioside A. These compounds are often studied through different preparations, including hexane fractions, chloroform fractions, and crude ethanolic extracts of the stem bark. Scientific investigations have highlighted the plant's potential efficacy in addressing serious conditions such as breast cancer, various other cancers, and chronic lymphocytic leukemia. Furthermore, its medicinal properties extend to the management of inflammatory responses, including collagen-induced arthritis.
- Synonyms
- Amoora Ficiformis · Dysoxylum Binectariferum · 13 more
- Common names
- Not available
- Family
- Meliaceae
- Distribution
- Not available
- Plant Parts
- Leaf · Stem
Classification
Common Names
Dysoxylum gotadhora is a remarkable botanical species known by a diverse array of regional names across various cultures. In Czech, it is referred to as nevoňavec horký, while in India, it carries the Kannada name ಕಾಡುಗಂಧ and the Malayalam name അകിൽ. Moving into Southeast Asia, the plant is identified as အောက်ချင်းစာနီပင် in Myanmar. Furthermore, it is recognized by the Chinese name 红果樫木, reflecting its widespread presence in different linguistic landscapes. These varied common names highlight the global significance and cultural recognition of this unique tree.
Sources: Catalogue of Life (COL)
Synonyms
Dysoxylum gotadhora is a complex botanical species that is frequently associated with several different scientific names. It is recognized by various synonyms, including the classifications Alliaria golodhara and Amoora ficiformis. Taxonomists also link this plant to Dysoxylum binectariferum, highlighting its intricate nomenclature. This relationship extends further to specific varieties such as Dysoxylum binectariferum var. coriaceum. Additionally, the plant is identified by the synonym Dysoxylum binectariferum var. punctulatum in various botanical records.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Dysoxylum gotadhora is a distinctive member of the kingdom Plantae. This species is classified under the class Equisetopsida, reflecting its structural botanical properties. Within this group, it belongs to the order Sapindales, a lineage that connects it to various other significant woody plants. It is further categorized under the genus Dysoxylum, which defines its specific morphological characteristics. Finally, it is a prominent representative of the family Meliaceae, showcasing its evolutionary placement within the mahogany family.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Sapindales |
| Family | Meliaceae |
| Genus | Dysoxylum |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Dysoxylum gotadhora exhibits a widespread geographical range that spans across various ecological zones in Asia. In temperate regions, the species is notably found throughout China, including the specific province of Hainan. Its presence extends into tropical climates, where it thrives across much of the Indian Subcontinent. Specifically, populations can be identified in the lush landscapes of Assam and Bangladesh. Furthermore, the plant maintains a significant distribution within the East Himalaya region, showcasing its adaptability to diverse environments.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Dysoxylum gotadhora is a self-supporting tree characterized by its robust and sturdy growth form. This species typically reaches a maximum height of 20 meters as it matures in its natural habitat. Its structural stability allows it to stand prominently within its ecosystem.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Dysoxylum gotadhora exhibits significant pharmacological potential through its diverse biological activities. Research indicates that this plant possesses notable antibacterial properties, offering a promising avenue for combating staphylococcal infections. Furthermore, the species demonstrates potent anticancer activity, particularly through the presence of bioactive compounds like rohitukine. This medicinal plant also shows specific antileukemic effects, as evidenced by its effectiveness against leukemia cell lines. Together, these therapeutic characteristics highlight the importance of the genus in the development of novel medicinal candidates.
Compounds
Dysoxylum gotadhora serves as a significant botanical source for several bioactive secondary metabolites. Specifically, this plant contains the chromone alkaloid rohitukine, which has inspired the development of potent cyclin-dependent kinase inhibitors. In addition to rohitukine, the species also contains rocaglaol, a compound known for its ability to inhibit Fli-1 transactivation. These chemical constituents highlight the medicinal importance of the genus in the search for novel anticancer treatments. Consequently, the presence of such diverse compounds underscores the therapeutic potential inherent in these plant extracts.
Conditions
Dysoxylum gotadhora exhibits significant therapeutic potential through its ability to treat various forms of cancer, including A549 lung carcinoma, HepG2 hepatocellular carcinoma, and MCF-7 breast adenocarcinoma. The plant also serves as a source for developing effective CDK inhibitors to combat oncological diseases. Furthermore, it demonstrates leishmanicidal activity against Leishmania donovani, addressing the causative agent of visceral leishmaniasis. These diverse biological activities highlight the plant's multifaceted medicinal value.
Preparations
Dysoxylum gotadhora is prepared as a chloroform fraction to study its specific inhibitory effects. The plant is also prepared as various extracts for medicinal investigation. Research involves using its hexane fraction to determine moderate biological activity. Additionally, it is prepared as a crude ethanolic extract of stem bark to test leishmanicidal properties. Finally, the plant is prepared as juices for use in anti-breast cancer treatments.
Parts used
Dysoxylum gotadhora is a plant species that possesses several biologically active components within its structural parts. Specifically, the plant contains leaves that serve as a significant source for isolating various chemical compounds. Furthermore, the stem of the plant also plays a vital role in its overall chemical profile. Research into these different plant parts can reveal essential properties for medicinal applications. Understanding these relationships between the plant and its leaves and stem is crucial for future botanical studies.