Dobera glabra

Dobera glabra · Accepted scientific name

Scientific literature: Very Sparse (1 studies) · ★☆☆☆☆

Dobera glabra is a botanical species recognized for its diverse therapeutic potential in traditional medicine. Researchers have specifically investigated the medicinal properties found within its foliage to discover new pharmacological applications. Studies have demonstrated that an aqueous leaves extract derived from this plant possesses significant bioactive compounds. Notably, these extracts have exhibited notable analgesic activities, providing relief from pain. This makes the plant a subject of great interest for the development of natural pain-management treatments.

Quick facts
Synonyms
Dobera Arabica · Dobera Coriacea · 3 more
Common names
Not available
Family
Salvadoraceae
Distribution
Not available
Plant Parts
Leaf

Classification

Synonyms

Dobera glabra is a botanical species that has been classified under several different names throughout its taxonomic history. Scientific literature identifies various synonyms for this plant, including Dobera arabica and Dobera coriacea. It is also frequently referred to in older texts as Dobera dubia or Salvadora glabra. Furthermore, the name Schizocalyx coriaceus is recognized as another valid synonym within its complex lineage. Understanding these diverse designations is essential for researchers tracking the plant's formal identity.

Sources: The World Checklist of Vascular Plants (WCVP)

Taxonomy

Dobera glabra is a fascinating specimen belonging to the kingdom Plantae. This plant is specifically classified under the class Equisetopsida and the order Brassicales. Within this botanical hierarchy, it is further organized into the genus Dobera. Ultimately, its taxonomic journey leads to its placement within the family Salvadoraceae. Understanding these biological relationships provides essential insight into the plant's evolutionary identity.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Brassicales
Family Salvadoraceae
Genus Dobera

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

Geographic Regions

Dobera glabra is a plant species with a wide geographic presence across the African continent. Its distribution spans much of East Tropical Africa, including notable populations in Kenya and Uganda. The species is also well-established within Northeast Tropical Africa, where it can be found in Djibouti and Eritrea. Furthermore, its range extends into the diverse landscapes of Ethiopia. This widespread presence highlights the plant's ability to thrive in various regional environments across the region.

Sources: The World Checklist of Vascular Plants (WCVP)

Identification

Morphology

Dobera glabra is a self-supporting species characterized by its distinctive tree-like growth form. This plant typically reaches a maximum height of 9 meters as it matures in its natural habitat. Its sturdy structure allows it to stand independently while contributing to the forest canopy.

Sources: Global Inventory of Floras and Traits (GIFT)

Biological Activities

Dobera glabra serves as a significant source of biological diversity, particularly through the phytochemical potential of its aqueous leaf extracts. Recent scientific investigations have focused on identifying the various phenolic compounds within the plant using advanced HPLC-ESI-MS analysis. These studies specifically highlight that the plant exhibits notable anti-inflammatory and analgesic properties. Through testing in animal models, researchers confirmed that the extract provides effective peripheral analgesic activity. Ultimately, these therapeutic effects are likely attributed to the presence of specific hydroxy and keto structures within the plant's chemical makeup.

Compounds

Conditions

Dobera glabra demonstrates significant therapeutic potential through its various biological activities. The plant effectively treats analgesic activities by providing both central and peripheral relief. It also treats anti-inflammatory conditions by reducing the immune expression of specific markers like MMP-9, TNF-α, and TGF-β1. Furthermore, Dobera glabra treats CCl4-induced changes in the genetic materials by reducing DNA fragmentation and ROS levels. Finally, the extract treats acetic acid-induced writhing in mice, confirming its peripheral analgesic effects.

Preparations

Dobera glabra is prepared as an aqueous leaves extract to facilitate detailed phytochemical and biological examinations. This specific preparation was analyzed using HPLC-ESI-MS, which successfully identified twenty different phenolic compounds within the extract. Researchers utilized this aqueous leaves extract to evaluate significant anti-inflammatory and analgesic properties in various animal models. The study demonstrated that the extract effectively decreases the immune expression of specific proteins like MMP-9 and TNF-α. Ultimately, the therapeutic potential of the Dobera glabra aqueous leaves extract is likely linked to its unique hydroxy and keto chemical structures.

Parts used

Dobera glabra is a highly valued tree species belonging to the Salvadoraceae family that offers significant biological potential. Recent scientific investigations have focused heavily on the leaves of this plant to identify their specific phytochemical properties. Through advanced analysis, researchers have successfully isolated various phenolic compounds and flavonoids from the aqueous leaf extracts. These leaf-derived constituents demonstrate notable anti-inflammatory, analgesic, and antioxidant activities in various biological models. Ultimately, the bioactive components found within the leaves of D. glabra may serve as valuable tools for treating hepatic oxidative stress and genotoxicity.