colic root

Dioscorea villosa · Accepted scientific name

Scientific literature: Very Extensive (381 studies) · ★★★★★

Colic root, scientifically known as Dioscorea villosa, is a perennial climbing herb native to North America. Renowned for its medicinal properties, it contains bioactive compounds like diosgenin. Traditionally used to alleviate menstrual cramps, digestive discomfort, and inflammatory conditions, this versatile plant remains a significant subject in ethnobotanical research.

Family
Dioscoreaceae
Native range
Northern America
Parts used
Not available
Common names
Colic Root · Four-Leaved Yam · 5 more
Scientific synonyms
Dioscorea Villosa Subsp. Glabrifolia · Dioscorea Villosa Var. Glabrifolia · 21 more

Names and Synonyms

Common Names

Scientific Names

Accepted name

Dioscorea villosa

Synonyms

Regional and Traditional Names

Spanish:

  • Ñame silvestre

German:

  • Wilde Yams
  • wilde Yamswurzel

French:

  • dioscorée velue
  • igname velue

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Dioscoreales, it is a member of the family Dioscoreaceae. It is specifically classified under the genus Dioscorea.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Dioscoreales
Family Dioscoreaceae
Genus Dioscorea

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a wide range of habitats across the North American landscape. In Eastern Canada, its presence is specifically noted within the province of Ontario. Moving into the North-Central United States, the species is well-distributed across several key states. It can be found growing in the fertile regions of Illinois, Iowa, and Kansas. Additionally, its geographical reach extends northward into the state of Minnesota.

Region Area
Eastern Canada Ontario
North-Central U.S.A. Illinois
North-Central U.S.A. Iowa
North-Central U.S.A. Kansas
North-Central U.S.A. Minnesota
North-Central U.S.A. Missouri
North-Central U.S.A. Nebraska
North-Central U.S.A. Oklahoma
North-Central U.S.A. Wisconsin
Northeastern U.S.A. Connecticut

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Life history

The life history of Dioscorea villosa is characterized by a perennial lifecycle, allowing the plant to persist through multiple growing seasons. As a geophyte, it relies on underground storage organs to survive unfavorable environmental conditions, ensuring its long-term survival in its habitat. This survival strategy is further supported by its classification as a cryptophyte, meaning its vital regenerative parts are protected beneath the soil surface, shielded from external stressors.

Life form :
geophyte
Life form :
cryptophyte
Lifecycle :
perennial

Morphology

The morphology of Dioscorea villosa is characterized by its growth form as a non-woody herb and specifically a forb, which utilizes an obligatory climbing habit to ascend toward light sources. As an independent organism, it does not function as a parasite, relying instead on its own metabolic processes for sustenance. Furthermore, it is a terrestrial plant, establishing its root systems and life cycle within the soil rather than as an epiphyte.

Climber :
obligatory
Epiphyte :
terrestrial
Growth form :
herb
Growth form :
forb
Parasite :
independent
Woodiness :
non-woody

Reproduction

The reproduction of Dioscorea villosa is characterized by a specific seasonal flowering period and a highly uniform seed production profile. The flowering cycle typically commences in April and continues through June, though the timing can remain variable depending on environmental conditions. Following pollination, the plant produces seeds with a remarkably consistent mass; the seed mass is recorded at a constant value of 0.0107 g, with the mean, maximum, and minimum measurements all aligning at this exact weight.

Flowering time :
Apr
Flowering time :
Jun
Seed mass mean:
0.0107 g

Sources: Global Inventory of Floras and Traits (GIFT)

Chemicals

Dioscorea villosa has 34 reported phytochemicals identified across 0 scientific publications and several other databases. The most consistently reported chemicals include DIOSGENIN, ALUMINUM, Ash, BETA-SITOSTEROL, CALCIUM.

Chemicals reported in Dioscorea villosa
Chemical Supporting sources Consensus
DIOSGENIN 3 supporting sources ★★☆☆☆
ALUMINUM 1 supporting sources ★☆☆☆☆
Ash 1 supporting sources ★☆☆☆☆
BETA-SITOSTEROL 1 supporting sources ★☆☆☆☆
CALCIUM 1 supporting sources ★☆☆☆☆
CAMPESTEROL 1 supporting sources ★☆☆☆☆
CHROMIUM 1 supporting sources ★☆☆☆☆
COBALT 1 supporting sources ★☆☆☆☆
Clionasterol 1 supporting sources ★☆☆☆☆
Dioscoreavilloside A 1 supporting sources ★☆☆☆☆

DIOSGENIN

  1. Dr. Duke
  2. Food & function
  3. Oxidative medicine and cellular longevity

ALUMINUM

  1. Dr. Duke

Ash

  1. Dr. Duke

BETA-SITOSTEROL

  1. Dr. Duke

CALCIUM

  1. Dr. Duke

CAMPESTEROL

  1. Dr. Duke

CHROMIUM

  1. Dr. Duke

COBALT

  1. Dr. Duke

Clionasterol

  1. Fitoterapia

Dioscoreavilloside A

  1. Planta medica

Activities

Dioscorea villosa has 324 reported activities identified across 0 scientific publications and several other databases. The most consistently reported activities include Anticancer, Hypolipidemic, ACE-Inhibitor, AP-1-Inhibitor, Absorbent.

Activities reported in Dioscorea villosa
Activity Supporting sources Consensus
Anticancer 2 supporting sources ★☆☆☆☆
Hypolipidemic 2 supporting sources ★☆☆☆☆
ACE-Inhibitor 1 supporting sources ★☆☆☆☆
AP-1-Inhibitor 1 supporting sources ★☆☆☆☆
Absorbent 1 supporting sources ★☆☆☆☆
Acidulant 1 supporting sources ★☆☆☆☆
Aldose-Reductase-Inhibitor 1 supporting sources ★☆☆☆☆
Allergenic 1 supporting sources ★☆☆☆☆
Amphiglycemic? 1 supporting sources ★☆☆☆☆
Analgesic 1 supporting sources ★☆☆☆☆

Anticancer

  1. Dr. Duke
  2. Food & function

Hypolipidemic

  1. Dr. Duke
  2. Food & function

ACE-Inhibitor

  1. Dr. Duke

AP-1-Inhibitor

  1. Dr. Duke

Absorbent

  1. Dr. Duke

Acidulant

  1. Dr. Duke

Aldose-Reductase-Inhibitor

  1. Dr. Duke

Allergenic

  1. Dr. Duke

Amphiglycemic?

  1. Dr. Duke

Analgesic

  1. Dr. Duke

Medicinal Uses

Dioscorea villosa has 16 reported medicinal uses identified across 0 scientific publications and several other databases. The most consistently reported uses include Alzheimer's disease, Parkinson's disease, aging, brain injury, cancers.

Most Reported Uses

Use Sources Consensus
Alzheimer's disease Oxidative medicine and cellular longevity (and other 1 sources) ★☆☆☆☆
Parkinson's disease Oxidative medicine and cellular longevity (and other 1 sources) ★☆☆☆☆
aging Oxidative medicine and cellular longevity (and other 1 sources) ★☆☆☆☆
brain injury Oxidative medicine and cellular longevity (and other 1 sources) ★☆☆☆☆
cancers Oxidative medicine and cellular longevity (and other 1 sources) ★☆☆☆☆
cognitive impairment Oxidative medicine and cellular longevity (and other 1 sources) ★☆☆☆☆
glioma Oxidative medicine and cellular longevity (and other 1 sources) ★☆☆☆☆
hyperlipidemia Oxidative medicine and cellular longevity (and other 1 sources) ★☆☆☆☆
infections Oxidative medicine and cellular longevity (and other 1 sources) ★☆☆☆☆
inflammation Oxidative medicine and cellular longevity (and other 1 sources) ★☆☆☆☆

Preparations

Preparations Sources Consensus
Gracillin Frontiers in oncology (and other 1 sources) ★☆☆☆☆
aqueous extracts Phytotherapy research : PTR (and other 1 sources) ★☆☆☆☆
plant extract Journal of natural products (and other 1 sources) ★☆☆☆☆
wild yam root Phytotherapy research : PTR (and other 1 sources) ★☆☆☆☆