the foxglove genus

Digitalis · Accepted scientific name

Scientific literature: Sparse (52 studies) · ★★☆☆☆

The foxglove genus, scientifically known as Digitalis, is a group of striking perennial plants renowned for their bell-shaped flowers. While celebrated for their ornamental beauty, they contain potent cardiac glycosides. These compounds are vital in modern medicine for treating heart failure, though the plant remains highly toxic if ingested.

Family
Plantaginaceae
Native range
Europe
Parts used
Leaf · Seed
Common names
Foxglove · Foxgloves
Scientific synonyms
Isoplexis · Callianassa · 1 more

Names and Synonyms

Common Names

Scientific Names

Accepted name

Digitalis

Synonyms

Regional and Traditional Names

Spanish:

  • Digitales
  • Dedaleras

German:

  • Fingerhüte
  • Fingerhut
  • Fingerhut
  • Fingerhüte

French:

  • digitale
  • Digitale

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Lamiales and family Plantaginaeceae, it is specifically classified under the genus Digitalis.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Lamiales
Family Plantaginaceae
Genus Digitalis

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a wide geographical range across several key regions of the European continent. In Northern Europe, its presence is well-documented in Denmark and Great Britain. It can also be found growing within the landscapes of Ireland and Sweden. Moving toward the central part of the continent, the species is distributed through Middle Europe. Specifically, its habitat extends into the mountainous and lowland regions of Austria.

Region Area
Northern Europe Denmark
Northern Europe Great Britain
Northern Europe Ireland
Northern Europe Sweden
Middle Europe Austria
Middle Europe Belgium
Middle Europe Czechia-Slovakia
Middle Europe Germany
Middle Europe Hungary
Middle Europe Netherlands

Sources: The World Checklist of Vascular Plants (WCVP)

Plant Parts

Digitalis has 2 reported plant parts identified across 3 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include leaf, seed.

Plant parts reported in Digitalis
Plant part Supporting sources Consensus
Leaf 2 supporting sources ★☆☆☆☆
Seed 1 supporting sources ★☆☆☆☆

Leaf

  1. Journal of receptor and signal transduction research
  2. Frontiers in plant science

Seed

  1. Journal of receptor and signal transduction research

Chemicals

Digitalis has 11 reported phytochemicals identified across 3 scientific publications and several other databases. The most consistently reported chemicals include digoxin, digitoxin, Cardiac Glycosides, Cardiotonic Steroids, Digitalis.

Chemicals reported in Digitalis
Chemical Supporting sources Consensus
digoxin 3 supporting sources ★★☆☆☆
digitoxin 2 supporting sources ★☆☆☆☆
Cardiac Glycosides 1 supporting sources ★☆☆☆☆
Cardiotonic Steroids 1 supporting sources ★☆☆☆☆
Digitalis 1 supporting sources ★☆☆☆☆
Digitoxose 1 supporting sources ★☆☆☆☆
STROPHANTHIN 1 supporting sources ★☆☆☆☆
beta-D-glucosides 1 supporting sources ★☆☆☆☆
beta-d-glucoside 1 supporting sources ★☆☆☆☆
bufalin 1 supporting sources ★☆☆☆☆

digoxin

  1. Blood purification
  2. Coronary artery disease
  3. Journal of receptor and signal transduction research

digitoxin

  1. Blood purification
  2. Journal of medicinal chemistry

Cardiac Glycosides

  1. Planta medica

Cardiotonic Steroids

  1. Journal of receptor and signal transduction research

Digitalis

  1. Cellular and molecular biology (Noisy-le-Grand, France)

Digitoxose

  1. Journal of medicinal chemistry

STROPHANTHIN

  1. Blood purification

beta-D-glucosides

  1. Journal of medicinal chemistry

beta-d-glucoside

  1. Journal of medicinal chemistry

bufalin

  1. Journal of receptor and signal transduction research

Activities

Digitalis has 3 reported activities identified across 3 scientific publications and several other databases. The most consistently reported activities include Antiadrenergic, Cardiotonic, Diuretic.

Activities reported in Digitalis
Activity Supporting sources Consensus
Antiadrenergic 1 supporting sources ★☆☆☆☆
Cardiotonic 1 supporting sources ★☆☆☆☆
Diuretic 1 supporting sources ★☆☆☆☆

Antiadrenergic

  1. Cardiovascular drugs and therapy

Cardiotonic

  1. Current pharmaceutical design

Diuretic

  1. Gaceta medica de Mexico

Conditions

Digitalis has 19 reported investigations on conditions identified across 3 scientific publications and several other databases. The most consistently reported conditions include congestive heart failure, heart failure, myocardial infarction, atrial fibrillation, coronary artery disease.

Conditions investigated for Digitalis
Condition Supporting sources Consensus
Congestive heart failure 5 supporting sources ★★★☆☆
Heart failure 4 supporting sources ★★☆☆☆
Myocardial infarction 3 supporting sources ★★☆☆☆
Atrial fibrillation 2 supporting sources ★☆☆☆☆
Coronary artery disease 2 supporting sources ★☆☆☆☆
Hsv-1 1 supporting sources ★☆☆☆☆
Atrial flutter 1 supporting sources ★☆☆☆☆
Cardiac disorders 1 supporting sources ★☆☆☆☆
Cardiotonic agent 1 supporting sources ★☆☆☆☆
Chronic renal insufficiency 1 supporting sources ★☆☆☆☆

Congestive heart failure

  1. Klinische Wochenschrift
  2. Coronary artery disease
  3. International journal of clinical practice
  4. Annals of internal medicine
  5. Journal of receptor and signal transduction research

Heart failure

  1. Coronary artery disease
  2. Arquivos brasileiros de cardiologia
  3. Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
  4. Deutsche medizinische Wochenschrift (1946)

Myocardial infarction

  1. International journal of clinical practice
  2. Cardiology clinics
  3. Current pharmaceutical design

Atrial fibrillation

  1. International journal of clinical practice
  2. Deutsche medizinische Wochenschrift (1946)

Coronary artery disease

  1. International journal of clinical practice
  2. Cardiology clinics

Hsv-1

  1. Chemistry & biodiversity

Atrial flutter

  1. Arquivos brasileiros de cardiologia

Cardiac disorders

  1. Cardiology clinics

Cardiotonic agent

  1. Gaceta medica de Mexico

Chronic renal insufficiency

  1. Blood purification

Preparations

Digitalis has 6 reported preparations identified across 3 scientific publications and several other databases. The most consistently reported preparations include Lanatoside C, dried leaves, intravenous digitalis, methanol extracts, ouabain infusion.

Preparations reported for Digitalis
Preparation Supporting sources Consensus
Lanatoside c 1 supporting sources ★☆☆☆☆
Dried leaves 1 supporting sources ★☆☆☆☆
Intravenous digitalis 1 supporting sources ★☆☆☆☆
Methanol extracts 1 supporting sources ★☆☆☆☆
Ouabain infusion 1 supporting sources ★☆☆☆☆
Seeds 1 supporting sources ★☆☆☆☆

Lanatoside c

  1. Circulation

Dried leaves

  1. Journal of receptor and signal transduction research

Intravenous digitalis

  1. International journal of clinical practice

Methanol extracts

  1. Frontiers in plant science

Ouabain infusion

  1. Circulation

Seeds

  1. Journal of receptor and signal transduction research