the foxglove genus
Digitalis · Accepted scientific name
Scientific literature: Sparse (52 studies) · ★★☆☆☆
The foxglove genus, scientifically known as Digitalis, is a group of striking perennial plants renowned for their bell-shaped flowers. While celebrated for their ornamental beauty, they contain potent cardiac glycosides. These compounds are vital in modern medicine for treating heart failure, though the plant remains highly toxic if ingested.
- Family
- Plantaginaceae
- Native range
- Europe
- Parts used
- Leaf · Seed
- Common names
- Foxglove · Foxgloves
- Scientific synonyms
- Isoplexis · Callianassa · 1 more
Names and Synonyms
Common Names
- foxglove
- Foxgloves
Scientific Names
Accepted name
DigitalisSynonyms
- Isoplexis
- Callianassa
- Dactylethria
Regional and Traditional Names
Spanish:
- Digitales
- Dedaleras
German:
- Fingerhüte
- Fingerhut
- Fingerhut
- Fingerhüte
French:
- digitale
- Digitale
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Lamiales and family Plantaginaeceae, it is specifically classified under the genus Digitalis.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Lamiales |
| Family | Plantaginaceae |
| Genus | Digitalis |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a wide geographical range across several key regions of the European continent. In Northern Europe, its presence is well-documented in Denmark and Great Britain. It can also be found growing within the landscapes of Ireland and Sweden. Moving toward the central part of the continent, the species is distributed through Middle Europe. Specifically, its habitat extends into the mountainous and lowland regions of Austria.
| Region | Area |
|---|---|
| Northern Europe | Denmark |
| Northern Europe | Great Britain |
| Northern Europe | Ireland |
| Northern Europe | Sweden |
| Middle Europe | Austria |
| Middle Europe | Belgium |
| Middle Europe | Czechia-Slovakia |
| Middle Europe | Germany |
| Middle Europe | Hungary |
| Middle Europe | Netherlands |
Sources: The World Checklist of Vascular Plants (WCVP)
Plant Parts
Digitalis has 2 reported plant parts identified across 3 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include leaf, seed.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Leaf | 2 supporting sources | ★☆☆☆☆ |
| Seed | 1 supporting sources | ★☆☆☆☆ |
Leaf
- Journal of receptor and signal transduction research
- Frontiers in plant science
Seed
- Journal of receptor and signal transduction research
Chemicals
Digitalis has 11 reported phytochemicals identified across 3 scientific publications and several other databases. The most consistently reported chemicals include digoxin, digitoxin, Cardiac Glycosides, Cardiotonic Steroids, Digitalis.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| digoxin | 3 supporting sources | ★★☆☆☆ |
| digitoxin | 2 supporting sources | ★☆☆☆☆ |
| Cardiac Glycosides | 1 supporting sources | ★☆☆☆☆ |
| Cardiotonic Steroids | 1 supporting sources | ★☆☆☆☆ |
| Digitalis | 1 supporting sources | ★☆☆☆☆ |
| Digitoxose | 1 supporting sources | ★☆☆☆☆ |
| STROPHANTHIN | 1 supporting sources | ★☆☆☆☆ |
| beta-D-glucosides | 1 supporting sources | ★☆☆☆☆ |
| beta-d-glucoside | 1 supporting sources | ★☆☆☆☆ |
| bufalin | 1 supporting sources | ★☆☆☆☆ |
digoxin
- Blood purification
- Coronary artery disease
- Journal of receptor and signal transduction research
digitoxin
- Blood purification
- Journal of medicinal chemistry
Cardiac Glycosides
- Planta medica
Cardiotonic Steroids
- Journal of receptor and signal transduction research
Digitalis
- Cellular and molecular biology (Noisy-le-Grand, France)
Digitoxose
- Journal of medicinal chemistry
STROPHANTHIN
- Blood purification
beta-D-glucosides
- Journal of medicinal chemistry
beta-d-glucoside
- Journal of medicinal chemistry
bufalin
- Journal of receptor and signal transduction research
Activities
Digitalis has 3 reported activities identified across 3 scientific publications and several other databases. The most consistently reported activities include Antiadrenergic, Cardiotonic, Diuretic.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Antiadrenergic | 1 supporting sources | ★☆☆☆☆ |
| Cardiotonic | 1 supporting sources | ★☆☆☆☆ |
| Diuretic | 1 supporting sources | ★☆☆☆☆ |
Antiadrenergic
- Cardiovascular drugs and therapy
Cardiotonic
- Current pharmaceutical design
Diuretic
- Gaceta medica de Mexico
Conditions
Digitalis has 19 reported investigations on conditions identified across 3 scientific publications and several other databases. The most consistently reported conditions include congestive heart failure, heart failure, myocardial infarction, atrial fibrillation, coronary artery disease.
| Condition | Supporting sources | Consensus |
|---|---|---|
| Congestive heart failure | 5 supporting sources | ★★★☆☆ |
| Heart failure | 4 supporting sources | ★★☆☆☆ |
| Myocardial infarction | 3 supporting sources | ★★☆☆☆ |
| Atrial fibrillation | 2 supporting sources | ★☆☆☆☆ |
| Coronary artery disease | 2 supporting sources | ★☆☆☆☆ |
| Hsv-1 | 1 supporting sources | ★☆☆☆☆ |
| Atrial flutter | 1 supporting sources | ★☆☆☆☆ |
| Cardiac disorders | 1 supporting sources | ★☆☆☆☆ |
| Cardiotonic agent | 1 supporting sources | ★☆☆☆☆ |
| Chronic renal insufficiency | 1 supporting sources | ★☆☆☆☆ |
Congestive heart failure
- Klinische Wochenschrift
- Coronary artery disease
- International journal of clinical practice
- Annals of internal medicine
- Journal of receptor and signal transduction research
Heart failure
- Coronary artery disease
- Arquivos brasileiros de cardiologia
- Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
- Deutsche medizinische Wochenschrift (1946)
Myocardial infarction
- International journal of clinical practice
- Cardiology clinics
- Current pharmaceutical design
Atrial fibrillation
- International journal of clinical practice
- Deutsche medizinische Wochenschrift (1946)
Coronary artery disease
- International journal of clinical practice
- Cardiology clinics
Hsv-1
- Chemistry & biodiversity
Atrial flutter
- Arquivos brasileiros de cardiologia
Cardiac disorders
- Cardiology clinics
Cardiotonic agent
- Gaceta medica de Mexico
Chronic renal insufficiency
- Blood purification
Preparations
Digitalis has 6 reported preparations identified across 3 scientific publications and several other databases. The most consistently reported preparations include Lanatoside C, dried leaves, intravenous digitalis, methanol extracts, ouabain infusion.
| Preparation | Supporting sources | Consensus |
|---|---|---|
| Lanatoside c | 1 supporting sources | ★☆☆☆☆ |
| Dried leaves | 1 supporting sources | ★☆☆☆☆ |
| Intravenous digitalis | 1 supporting sources | ★☆☆☆☆ |
| Methanol extracts | 1 supporting sources | ★☆☆☆☆ |
| Ouabain infusion | 1 supporting sources | ★☆☆☆☆ |
| Seeds | 1 supporting sources | ★☆☆☆☆ |
Lanatoside c
- Circulation
Dried leaves
- Journal of receptor and signal transduction research
Intravenous digitalis
- International journal of clinical practice
Methanol extracts
- Frontiers in plant science
Ouabain infusion
- Circulation
Seeds
- Journal of receptor and signal transduction research