woolly foxglove
Digitalis lanata · Accepted scientific name
Scientific literature: Very Extensive (278 studies) · ★★★★★
Woolly foxglove, scientifically known as Digitalis lanaata, is a striking perennial herb native to the high-altitude regions of the Himalayas. Characterized by its densely pubescent, velvety leaves and bell-shaped flowers, this potent medicinal plant contains cardiac glycosides, historically utilized for treating heart conditions and regulating rhythmic palpitations.
- Family
- Plantaginaceae
- Native range
- Europe
- Parts used
- Leaf
- Common names
- Grecian Foxglove · Woolly Foxglove · 2 more
- Scientific synonyms
- Not available
Names and Synonyms
Common Names
- Grecian foxglove
- woolly foxglove
- digitalis
- woolly digitalis
Scientific Names
Accepted name
Digitalis lanataRegional and Traditional Names
Spanish:
- digital
German:
- Wolliger Fingerhut
- wolliger Fingerhut
French:
- Digitale laineuse
- digitale laineuse
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant, Digitalis lanata, belongs to the kingdom Plantae and the phylum Streptophyta. Within the class Equisetopsida and subclass Magnoliidae, it is classified under the order Lamiales and the family Plantaginaceae. Finally, it is identified by the genus Digitalis.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Lamiales |
| Family | Plantaginaceae |
| Genus | Digitalis |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a widespread distribution across several regions of the European continent. In Middle Europe, it can be found growing within the borders of Austria and Germany. Its presence extends through the territories of Czechia and Slovakia as well. Additionally, the species is documented throughout Hungary, contributing to its central European range. Finally, the distribution reaches into Southeastern Europe, specifically within the country of Albania.
| Region | Area |
|---|---|
| Middle Europe | Austria |
| Middle Europe | Czechia-Slovakia |
| Middle Europe | Germany |
| Middle Europe | Hungary |
| Southeastern Europe | Albania |
| Southeastern Europe | Bulgaria |
| Southeastern Europe | Greece |
| Southeastern Europe | Romania |
| Southeastern Europe | Türkiye-in-Europe |
| Southeastern Europe | NW. Balkan Pen. |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Ecology
The ecology of Digitalis lanata is characterized by its preference for diverse and varied landscapes, where it thrives across a spectrum of elevations and vegetation types. This species is commonly found inhabiting forest environments, rolling hills, open meadows, and rugged mountain terrains. It demonstrates a notable adaptability to different successional stages of land, frequently establishing itself within shrubberies where it can compete for light and nutrients. By occupying these distinct niches, from shaded woodland floors to more exposed montane regions, the plant utilizes a wide range of microclimates provided by these varied topographical features.
- Habitat :
- forest, hills, meadows, mountains, shrubberies
Life history
The life history of Digitalis lanata is characterized by its classification as a perennial species, allowing it to persist through multiple growing seasons. In terms of its growth habit and structural adaptation to its environment, the plant functions as a hemicryptophyte, a life form where the perennating buds are located at the soil surface, protected by leaf litter or soil. This hemicryptophytic strategy ensures its survival through unfavorable periods, maintaining its presence within its ecological niche over a long-term lifecycle.
- Life form :
- hemicryptophyte
- Lifecycle :
- perennial
Morphology
The morphology of Digitalis lanata is characterized by its growth form as a non-woody herb, specifically classified as a forb. It is a self-supporting plant that does not function as a climber or a liana, and it exists as an independent organism rather than a parasite. This terrestrial species typically reaches a plant height ranging from a minimum of 0.4 m to a maximum of 1 m, with a mean height of approximately 0.6 m.
- Aquatic :
- terrestrial
- Climber :
- self-supporting
- Epiphyte :
- terrestrial
- Growth form :
- herb
- Growth form :
- forb
- Parasite :
- independent
- Plant height max:
- 1 m
- Plant height mean:
- 0.6 m
- Plant height min:
- 0.4 m
- Woodiness :
- non-woody
Physiology
The physiology of Digitalis lanata is characterized by its metabolic processes and structural adaptations, most notably its reliance on the C3 photosynthetic pathway for carbon fixation. As a C3 plant, it utilizes the enzyme Rubisco to fix atmospheric carbon dioxide into a three-carbon compound during the Calvin cycle, a process that is highly efficient under temperate conditions but sensitive to photorespiration in high-temperature environments. The plant's physiological profile is heavily defined by the biosynthesis of potent cardiac glycosides, such as digoxin and digitoxin, which are produced through complex secondary metabolic pathways involving steroid precursors. These bioactive compounds are synthesized and sequestered within specialized vacuoles to serve as chemical defenses. Furthermore, the plant exhibits specialized water regulation and nutrient uptake mechanisms to support the high energy demands of producing these complex glycosides, maintaining cellular homeostasis through active transport and osmotic regulation within its leaf and stem tissues.
- Photosynthetic pathway :
- C3
Reproduction
The reproduction of Digitalis lanata is characterized by a specific seasonal flowering window and the production of minute seeds. The flowering period typically commences in July and concludes in August, though the timing can remain variable depending on environmental conditions. Following successful pollination, the plant produces seeds with a very small mass; the mean seed mass is recorded at 0.000306 g, with a maximum recorded mass of 0.0005 g (5e-04 g) and a minimum mass of 0.00035 g.
- Flowering time :
- Jul
- Flowering time :
- Aug
- Seed mass max:
- 5e-04 g
- Seed mass mean:
- 0.000306 g
- Seed mass min:
- 0.00035 g
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Digitalis lanata has 1 reported plant parts identified across 6 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include leaf.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Leaf | 6 supporting sources | ★★★☆☆ |
Leaf
- Journal of chromatography. A
- British heart journal
- Journal of natural products
- Journal of chromatography
- Analytical biochemistry
View 1 additional sources
- Die Pharmazie
Chemicals
Digitalis lanata has 85 reported phytochemicals identified across 6 scientific publications and several other databases. The most consistently reported chemicals include digoxin, Cardenolides, lanatoside C, Digoxigenin, Glucodigifucoside.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| digoxin | 8 supporting sources | ★★★★☆ |
| Cardenolides | 5 supporting sources | ★★★☆☆ |
| lanatoside C | 5 supporting sources | ★★★☆☆ |
| Digoxigenin | 3 supporting sources | ★★☆☆☆ |
| Glucodigifucoside | 3 supporting sources | ★★☆☆☆ |
| pregnenolone | 3 supporting sources | ★★☆☆☆ |
| progesterone | 3 supporting sources | ★★☆☆☆ |
| Cardiac Glycosides | 2 supporting sources | ★☆☆☆☆ |
| Digitoxigenin | 2 supporting sources | ★☆☆☆☆ |
| Digitoxigenin bisdigitoxoside | 2 supporting sources | ★☆☆☆☆ |
digoxin
- Dr. Duke
- British heart journal
- Journal of biotechnology
- Journal of natural products
- Bioorganicheskaia khimiia
View 3 additional sources
- Prikladnaia biokhimiia i mikrobiologiia
- Analytical biochemistry
- Die Pharmazie
Cardenolides
- Bioorganicheskaia khimiia
- Journal of natural products
- Frontiers in plant science
- The Biochemical journal
- Journal of chromatography
lanatoside C
- Dr. Duke
- Planta medica
- Bioorganicheskaia khimiia
- Frontiers in plant science
- Analytical biochemistry
Digoxigenin
- Dr. Duke
- Current pharmaceutical design
- Acta crystallographica. Section B, Structural science
Glucodigifucoside
- Dr. Duke
- Planta medica
- Journal of chromatography
pregnenolone
- Planta
- Zeitschrift fur Naturforschung. C, Journal of biosciences
- Science (New York, N.Y.)
progesterone
- Zeitschrift fur Naturforschung. C, Journal of biosciences
- The Biochemical journal
- Science (New York, N.Y.)
Cardiac Glycosides
- Journal of chromatography. A
- Planta medica
Digitoxigenin
- Dr. Duke
- The Biochemical journal
Digitoxigenin bisdigitoxoside
- Dr. Duke
- Acta crystallographica. Section B, Structural science
Activities
Digitalis lanata has 125 reported activities identified across 6 scientific publications and several other databases. The most consistently reported activities include Aldose-Reductase-Inhibitor, Allergenic, AntiHIV, Antiallergic, Antialzheimeran.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Aldose-Reductase-Inhibitor | 1 supporting sources | ★☆☆☆☆ |
| Allergenic | 1 supporting sources | ★☆☆☆☆ |
| AntiHIV | 1 supporting sources | ★☆☆☆☆ |
| Antiallergic | 1 supporting sources | ★☆☆☆☆ |
| Antialzheimeran | 1 supporting sources | ★☆☆☆☆ |
| Antiamblyopic | 1 supporting sources | ★☆☆☆☆ |
| Antiangiogenic | 1 supporting sources | ★☆☆☆☆ |
| Antiatherogenic | 1 supporting sources | ★☆☆☆☆ |
| Antibacterial | 1 supporting sources | ★☆☆☆☆ |
| Anticarcinogenic | 1 supporting sources | ★☆☆☆☆ |
Aldose-Reductase-Inhibitor
- Dr. Duke
Allergenic
- Dr. Duke
AntiHIV
- Dr. Duke
Antiallergic
- Dr. Duke
Antialzheimeran
- Dr. Duke
Antiamblyopic
- Dr. Duke
Antiangiogenic
- Dr. Duke
Antiatherogenic
- Dr. Duke
Antibacterial
- Dr. Duke
Anticarcinogenic
- Dr. Duke
Medicinal Uses
Digitalis lanata has 6 reported medicinal uses identified across 6 scientific publications and several other databases. The most consistently reported uses include cardiovascular diseases, ischemia, myocardial infarct, necrosis, prostate cancer.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| cardiovascular diseases | Current pharmaceutical design (and other 1 sources) | ★☆☆☆☆ |
| ischemia | American heart journal (and other 1 sources) | ★☆☆☆☆ |
| myocardial infarct | American heart journal (and other 1 sources) | ★☆☆☆☆ |
| necrosis | American heart journal (and other 1 sources) | ★☆☆☆☆ |
| prostate cancer | Current pharmaceutical design (and other 1 sources) | ★☆☆☆☆ |
| tumor | Journal of biomolecular screening (and other 1 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| Suspension cultures | Zeitschrift fur Naturforschung. C, Journal of biosciences (and other 1 sources) | ★☆☆☆☆ |
| cell cultures | Zeitschrift fur Naturforschung. C, Journal of biosciences (and other 1 sources) | ★☆☆☆☆ |
| dried leaf powder | Journal of chromatography (and other 1 sources) | ★☆☆☆☆ |
| hydromethanolic extract | Journal of chromatography. A (and other 1 sources) | ★☆☆☆☆ |
| leaves | British heart journal (and other 1 sources) | ★☆☆☆☆ |
| light- or dark-grown shoot cultures | Zeitschrift fur Naturforschung. C, Journal of biosciences (and other 1 sources) | ★☆☆☆☆ |
| proembryonic masses (PEMs) | Planta (and other 1 sources) | ★☆☆☆☆ |
| suspension cultures | Zeitschrift fur Naturforschung. C, Journal of biosciences (and other 1 sources) | ★☆☆☆☆ |
| tissue cultures | Zeitschrift fur Naturforschung. C, Journal of biosciences (and other 1 sources) | ★☆☆☆☆ |