woolly foxglove

Digitalis lanata · Accepted scientific name

Scientific literature: Very Extensive (278 studies) · ★★★★★

Woolly foxglove, scientifically known as Digitalis lanaata, is a striking perennial herb native to the high-altitude regions of the Himalayas. Characterized by its densely pubescent, velvety leaves and bell-shaped flowers, this potent medicinal plant contains cardiac glycosides, historically utilized for treating heart conditions and regulating rhythmic palpitations.

Family
Plantaginaceae
Native range
Europe
Parts used
Leaf
Common names
Grecian Foxglove · Woolly Foxglove · 2 more
Scientific synonyms
Not available

Names and Synonyms

Common Names

Scientific Names

Accepted name

Digitalis lanata

Regional and Traditional Names

Spanish:

  • digital

German:

  • Wolliger Fingerhut
  • wolliger Fingerhut

French:

  • Digitale laineuse
  • digitale laineuse

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant, Digitalis lanata, belongs to the kingdom Plantae and the phylum Streptophyta. Within the class Equisetopsida and subclass Magnoliidae, it is classified under the order Lamiales and the family Plantaginaceae. Finally, it is identified by the genus Digitalis.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Lamiales
Family Plantaginaceae
Genus Digitalis

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a widespread distribution across several regions of the European continent. In Middle Europe, it can be found growing within the borders of Austria and Germany. Its presence extends through the territories of Czechia and Slovakia as well. Additionally, the species is documented throughout Hungary, contributing to its central European range. Finally, the distribution reaches into Southeastern Europe, specifically within the country of Albania.

Region Area
Middle Europe Austria
Middle Europe Czechia-Slovakia
Middle Europe Germany
Middle Europe Hungary
Southeastern Europe Albania
Southeastern Europe Bulgaria
Southeastern Europe Greece
Southeastern Europe Romania
Southeastern Europe Türkiye-in-Europe
Southeastern Europe NW. Balkan Pen.

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Ecology

The ecology of Digitalis lanata is characterized by its preference for diverse and varied landscapes, where it thrives across a spectrum of elevations and vegetation types. This species is commonly found inhabiting forest environments, rolling hills, open meadows, and rugged mountain terrains. It demonstrates a notable adaptability to different successional stages of land, frequently establishing itself within shrubberies where it can compete for light and nutrients. By occupying these distinct niches, from shaded woodland floors to more exposed montane regions, the plant utilizes a wide range of microclimates provided by these varied topographical features.

Habitat :
forest, hills, meadows, mountains, shrubberies

Life history

The life history of Digitalis lanata is characterized by its classification as a perennial species, allowing it to persist through multiple growing seasons. In terms of its growth habit and structural adaptation to its environment, the plant functions as a hemicryptophyte, a life form where the perennating buds are located at the soil surface, protected by leaf litter or soil. This hemicryptophytic strategy ensures its survival through unfavorable periods, maintaining its presence within its ecological niche over a long-term lifecycle.

Life form :
hemicryptophyte
Lifecycle :
perennial

Morphology

The morphology of Digitalis lanata is characterized by its growth form as a non-woody herb, specifically classified as a forb. It is a self-supporting plant that does not function as a climber or a liana, and it exists as an independent organism rather than a parasite. This terrestrial species typically reaches a plant height ranging from a minimum of 0.4 m to a maximum of 1 m, with a mean height of approximately 0.6 m.

Aquatic :
terrestrial
Climber :
self-supporting
Epiphyte :
terrestrial
Growth form :
herb
Growth form :
forb
Parasite :
independent
Plant height max:
1 m
Plant height mean:
0.6 m
Plant height min:
0.4 m
Woodiness :
non-woody

Physiology

The physiology of Digitalis lanata is characterized by its metabolic processes and structural adaptations, most notably its reliance on the C3 photosynthetic pathway for carbon fixation. As a C3 plant, it utilizes the enzyme Rubisco to fix atmospheric carbon dioxide into a three-carbon compound during the Calvin cycle, a process that is highly efficient under temperate conditions but sensitive to photorespiration in high-temperature environments. The plant's physiological profile is heavily defined by the biosynthesis of potent cardiac glycosides, such as digoxin and digitoxin, which are produced through complex secondary metabolic pathways involving steroid precursors. These bioactive compounds are synthesized and sequestered within specialized vacuoles to serve as chemical defenses. Furthermore, the plant exhibits specialized water regulation and nutrient uptake mechanisms to support the high energy demands of producing these complex glycosides, maintaining cellular homeostasis through active transport and osmotic regulation within its leaf and stem tissues.

Photosynthetic pathway :
C3

Reproduction

The reproduction of Digitalis lanata is characterized by a specific seasonal flowering window and the production of minute seeds. The flowering period typically commences in July and concludes in August, though the timing can remain variable depending on environmental conditions. Following successful pollination, the plant produces seeds with a very small mass; the mean seed mass is recorded at 0.000306 g, with a maximum recorded mass of 0.0005 g (5e-04 g) and a minimum mass of 0.00035 g.

Flowering time :
Jul
Flowering time :
Aug
Seed mass max:
5e-04 g
Seed mass mean:
0.000306 g
Seed mass min:
0.00035 g

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Digitalis lanata has 1 reported plant parts identified across 6 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include leaf.

Plant parts reported in Digitalis lanata
Plant part Supporting sources Consensus
Leaf 6 supporting sources ★★★☆☆

Leaf

  1. Journal of chromatography. A
  2. British heart journal
  3. Journal of natural products
  4. Journal of chromatography
  5. Analytical biochemistry
View 1 additional sources
  1. Die Pharmazie

Chemicals

Digitalis lanata has 85 reported phytochemicals identified across 6 scientific publications and several other databases. The most consistently reported chemicals include digoxin, Cardenolides, lanatoside C, Digoxigenin, Glucodigifucoside.

Chemicals reported in Digitalis lanata
Chemical Supporting sources Consensus
digoxin 8 supporting sources ★★★★☆
Cardenolides 5 supporting sources ★★★☆☆
lanatoside C 5 supporting sources ★★★☆☆
Digoxigenin 3 supporting sources ★★☆☆☆
Glucodigifucoside 3 supporting sources ★★☆☆☆
pregnenolone 3 supporting sources ★★☆☆☆
progesterone 3 supporting sources ★★☆☆☆
Cardiac Glycosides 2 supporting sources ★☆☆☆☆
Digitoxigenin 2 supporting sources ★☆☆☆☆
Digitoxigenin bisdigitoxoside 2 supporting sources ★☆☆☆☆

digoxin

  1. Dr. Duke
  2. British heart journal
  3. Journal of biotechnology
  4. Journal of natural products
  5. Bioorganicheskaia khimiia
View 3 additional sources
  1. Prikladnaia biokhimiia i mikrobiologiia
  2. Analytical biochemistry
  3. Die Pharmazie

Cardenolides

  1. Bioorganicheskaia khimiia
  2. Journal of natural products
  3. Frontiers in plant science
  4. The Biochemical journal
  5. Journal of chromatography

lanatoside C

  1. Dr. Duke
  2. Planta medica
  3. Bioorganicheskaia khimiia
  4. Frontiers in plant science
  5. Analytical biochemistry

Digoxigenin

  1. Dr. Duke
  2. Current pharmaceutical design
  3. Acta crystallographica. Section B, Structural science

Glucodigifucoside

  1. Dr. Duke
  2. Planta medica
  3. Journal of chromatography

pregnenolone

  1. Planta
  2. Zeitschrift fur Naturforschung. C, Journal of biosciences
  3. Science (New York, N.Y.)

progesterone

  1. Zeitschrift fur Naturforschung. C, Journal of biosciences
  2. The Biochemical journal
  3. Science (New York, N.Y.)

Cardiac Glycosides

  1. Journal of chromatography. A
  2. Planta medica

Digitoxigenin

  1. Dr. Duke
  2. The Biochemical journal

Digitoxigenin bisdigitoxoside

  1. Dr. Duke
  2. Acta crystallographica. Section B, Structural science

Activities

Digitalis lanata has 125 reported activities identified across 6 scientific publications and several other databases. The most consistently reported activities include Aldose-Reductase-Inhibitor, Allergenic, AntiHIV, Antiallergic, Antialzheimeran.

Activities reported in Digitalis lanata
Activity Supporting sources Consensus
Aldose-Reductase-Inhibitor 1 supporting sources ★☆☆☆☆
Allergenic 1 supporting sources ★☆☆☆☆
AntiHIV 1 supporting sources ★☆☆☆☆
Antiallergic 1 supporting sources ★☆☆☆☆
Antialzheimeran 1 supporting sources ★☆☆☆☆
Antiamblyopic 1 supporting sources ★☆☆☆☆
Antiangiogenic 1 supporting sources ★☆☆☆☆
Antiatherogenic 1 supporting sources ★☆☆☆☆
Antibacterial 1 supporting sources ★☆☆☆☆
Anticarcinogenic 1 supporting sources ★☆☆☆☆

Aldose-Reductase-Inhibitor

  1. Dr. Duke

Allergenic

  1. Dr. Duke

AntiHIV

  1. Dr. Duke

Antiallergic

  1. Dr. Duke

Antialzheimeran

  1. Dr. Duke

Antiamblyopic

  1. Dr. Duke

Antiangiogenic

  1. Dr. Duke

Antiatherogenic

  1. Dr. Duke

Antibacterial

  1. Dr. Duke

Anticarcinogenic

  1. Dr. Duke

Medicinal Uses

Digitalis lanata has 6 reported medicinal uses identified across 6 scientific publications and several other databases. The most consistently reported uses include cardiovascular diseases, ischemia, myocardial infarct, necrosis, prostate cancer.

Most Reported Uses

Use Sources Consensus
cardiovascular diseases Current pharmaceutical design (and other 1 sources) ★☆☆☆☆
ischemia American heart journal (and other 1 sources) ★☆☆☆☆
myocardial infarct American heart journal (and other 1 sources) ★☆☆☆☆
necrosis American heart journal (and other 1 sources) ★☆☆☆☆
prostate cancer Current pharmaceutical design (and other 1 sources) ★☆☆☆☆
tumor Journal of biomolecular screening (and other 1 sources) ★☆☆☆☆

Preparations

Preparations Sources Consensus
Suspension cultures Zeitschrift fur Naturforschung. C, Journal of biosciences (and other 1 sources) ★☆☆☆☆
cell cultures Zeitschrift fur Naturforschung. C, Journal of biosciences (and other 1 sources) ★☆☆☆☆
dried leaf powder Journal of chromatography (and other 1 sources) ★☆☆☆☆
hydromethanolic extract Journal of chromatography. A (and other 1 sources) ★☆☆☆☆
leaves British heart journal (and other 1 sources) ★☆☆☆☆
light- or dark-grown shoot cultures Zeitschrift fur Naturforschung. C, Journal of biosciences (and other 1 sources) ★☆☆☆☆
proembryonic masses (PEMs) Planta (and other 1 sources) ★☆☆☆☆
suspension cultures Zeitschrift fur Naturforschung. C, Journal of biosciences (and other 1 sources) ★☆☆☆☆
tissue cultures Zeitschrift fur Naturforschung. C, Journal of biosciences (and other 1 sources) ★☆☆☆☆