Dicoma tomentosa
Dicoma tomentosa · Accepted scientific name
Scientific literature: Very Sparse (1 studies) · ★☆☆☆☆
Dicoma tomentosa is a specialized plant species recognized for its significant presence in ethnobotanical research. Scientific investigations have highlighted its diverse pharmacological potential, particularly regarding its impressive antiplasmodial properties. Beyond its impact on malaria, the plant has demonstrated effective anthelmintic activities useful in treating parasitic infections. Furthermore, recent studies have explored its promising antiHIV and antibacterial capabilities in combating various pathogens. These multifaceted biological activities position this species as a valuable subject for future medicinal developments.
- Synonyms
- Dicoma Gnaphaloides · Dicoma Lanuginosa · 2 more
- Common names
- Not available
- Family
- Not available
- Distribution
- Not available
- Plant Parts
- Not available
Classification
Synonyms
Dicoma tomentosa is a botanical subject characterized by a complex web of taxonomic synonyms that can often confuse researchers. This plant is frequently identified in historical literature under the name Acilepis lanata or as Dicoma gnaphaloides. Furthermore, various botanical records may refer to the species as Dicoma lanuginosa depending on the specific classification system used. It has also been associated with the names Onopordum lanatum and Schaffnera carduoides in different scientific contexts. Navigating these various nomenclatural relationships is essential for maintaining accuracy in botanical studies.
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Dicoma tomentosa is a plant species with a diverse distribution spanning several regions across the African continent. Within East Tropical Africa, it can be found growing in the landscapes of Kenya, Tanzania, and Uganda. The species also extends into Northeast Tropical Africa, where it is established in Chad. Furthermore, its presence is noted within the territory of Eritrea. This broad geographic range highlights the plant's ability to thrive across various African environments.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Dicoma tomentosa is characterized by its distinct growth form as an herb. This self-supporting plant typically maintains a relatively modest stature in its natural habitat. While its height can reach a maximum of 0.5 m, it is also capable of growing up to 1 m under certain conditions. These physical traits define its presence within its specific ecological niche.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Dicoma tomentosa has demonstrated significant antiplasmodial activity through recent scientific evaluation of medicinal plants from Burkina Faso. During in vitro testing against the Plasmodium falciparum 3D7 chloroquine-sensitive strain, extracts from the whole plant yielded some of the most impressive results. Specifically, the extracts displayed promising potency with IC(50) values ranging between 7.0 and 14.0 microg/ml. This plant emerged alongside Psorospermum senegalense as a top candidate for future pharmaceutical research due to its effectiveness. Consequently, this study marks the first time the antiplasmodial properties of this Asteraceae species have been officially reported.
Compounds
Conditions
Dicoma tomentosa exhibits significant antiplasmodial activity against the Plasmodium falciparum 3D7 chloroquine-sensitive strain. Extracts derived from the whole plant of this species yielded some of the best results in the study, with IC50 values ranging between 7.0 and 14.0 microg/ml. This plant was identified as one of the most promising candidates for treating malaria due to its potent inhibitory effects. Further testing confirmed its effectiveness against the chloroquine-resistant W2 strain as well. Consequently, Dicoma tomentosa stands out as a primary subject for continued investigation regarding its medicinal properties.