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Updated: Oct 20, 2024

What to know about Cynara scolymus before using it medicinally

Cynara scolymus plant

Cynara scolymus, commonly known as globe artichoke, has been traditionally used in the treatment of various health conditions, including liver and gallbladder disorders, digestive issues, and high cholesterol.

The herb is valued for its ability to promote overall health and wellness, with its main health benefits including antioxidant, anti-inflammatory, and hepatoprotective properties. The main therapeutic properties of Cynara scolymus include its ability to stimulate bile production, improve digestion, and protect against liver damage. The herb is rich in bioactive compounds such as cynarin, silymarin, and flavonoids, which have been shown to have antioxidant and anti-inflammatory effects.

A common herbal preparation made from Cynara scolymus is a leaf extract or a standardized cynarin-rich extract, which is often used to support liver health and improve digestion.

The following article explains in detail what are the medicinal uses of Cynara scolymus, its health benefits, therapeutic properties, bioactive compounds, used parts, and herbal preparation. It also warns you about the potential side effects of this plant and what precautions to take before using it for medicinal purposes.

ARTICLE SUMMARY: The table below summarizes the most crucial information about Cynara scolymus provided in the article below, which is useful if you are in a hurry and don't have time to dig deep into the very detailed content that follows.

Medicinal AspectSummary
UsesDiabetes, Hypertension, Arthritis, Gout, Kidney stones, Asthma, Inflammation, Obesity, Hyperlipidemia, Osteoporosis
BenefitsReduces inflammation, Lowers blood pressure, Decreases cancer risk, Improves digestion, Boosts immune system, Suppresses oxidative stress, Enhances cognitive function, Regulates blood sugar, Prevents cardiovascular disease, Fights antioxidant deficiency
PropertiesAntioxidant, Anti-inflammatory, Antimicrobial, Antidiabetic, Hypolipidemic, Antioxidative, Cardioprotective, Hypotensive, Analgesic
ConstituentsSaponins, Flavonoids, Phenolic acids, Glycosides, Sterols, Triterpenoids, Alkaloids, Quercetin, Carotenoids, Anthocyanins
PartsFlowers, Leaves
PreparationsTincture, Suppository, Salve, Decoction, Tea, Capsule
Side EffectsExperience renal impairment, Develop gastrointestinal disturbances, Suffer from diarrhea, Experience allergic reactions, Develop hypokalemia, Experience muscle weakness, Develop hypernatremia, Suffer from hypotension, Experience cardiovascular issues, Develop electrolyte imbalance
PrecautionConsult a healthcare professional, Follow recommended dosage, Avoid allergic reactions, Monitor blood pressure, Be cautious with interactions, Avoid in pregnancy and breastfeeding, Report side effects, Be aware of kidney function, Monitor liver function, Avoid with certain medical conditions

BONUS CHEATSHEET: The cheatsheet below illustrates the most important medicinal aspects of Cynara scolymus. Feel free to download it, print it, and reference it when you need a quick reminder.

Cynara scolymus plant cheatsheet

What are the main medicinal uses of Cynara scolymus?

The main medicinal uses of Cynara scolymus are the relief of hypertension, digestive issues, and gastritis, due to its high content of flavonoids and phenolic acids, which have been shown to lower blood pressure and reduce inflammation in the digestive system.

Additionally, its ability to regulate blood sugar levels makes it beneficial for diabetes management. Its antioxidant and anti-inflammatory properties also contribute to its effectiveness in reducing symptoms of obesity, hyperlipidemia, and arthritis, as well as preventing the formation of kidney stones. Furthermore, Cynara scolymus has been found to have a diuretic effect, which can help alleviate gout symptoms.

Its anti-inflammatory and antioxidant constituents also make it effective in reducing inflammation, which is a common underlying factor in many chronic diseases.

The following illustration give a summary of the main medicinal uses of Cynara scolymus.

uses of Cynara scolymus

The list below provide more details on why Cynara scolymus is used to alleviate the health conditions mentioned in the illustration above.

The table that follows gives an overview of what are the most common health conditions that are treated with Cynara scolymus, in each of the major medicinal systems.

Medicinal SystemConditions Treated
Modern Western MedicineHypertension, Diabetes, Gout, Atherosclerosis, Obesity, Kidney Stones, Arthritis, Osteoporosis, Hypercholesterolemia, Cardiovascular Disease, Inflammation, Hyperlipidemia, Cancer Prevention, Asthma, Hyperuricemia, Cancer, Digestive Issues, Inflammatory Bowel Disease, Gastroesophageal Reflux, High Cholesterol
Traditional Chinese MedicineDiabetes, Hypertension, Gout, Arthritis, Inflammation, Obesity, Osteoporosis, Kidney Stones, Cancer Prevention, Digestive Issues, High Cholesterol, Asthma, Gastritis, Atherosclerosis, Hyperlipidemia, Cardiovascular Disease, Liver Disease, Hyperuricemia, Eczema, Rheumatism
Ayurvedic MedicineDiabetes, Hypertension, Rheumatoid Arthritis, Gout, Asthma, Inflammation, Gastritis, Hyperlipidemia, Cancer Prevention, Obesity, Kidney Stones, Osteoporosis, Cholesterol, Gastric Ulcers, Eczema, Digestive Issues, Atherosclerosis, Inflammatory Bowel Disease, High Blood Pressure, Thyroid Issues
Unani MedicineDiabetes, Hypertension, Gout, Arthritis, Kidney Stones, Hyperlipidemia, Obesity, Asthma, Atherosclerosis, Gastritis, Osteoporosis, Cholesterol, Digestive Issues, Rheumatism, Inflammation, Cancer Prevention, Cancer, Eczema, Inflammatory Bowel Disease, Hyperuricemia
Homeopathic MedicineDiabetes, Hypertension, Arthritis, Gout, Kidney Stones, Osteoporosis, Gastritis, Inflammation, Atherosclerosis, Cholesterol, Hyperlipidemia, Asthma, Digestive Issues, Obesity, High Blood Pressure, Cancer, Cancer Prevention, Hypothyroidism, Eczema, Ulcerative Colitis

Modern Western Medicine

In modern western medicine, Cynara scolymus is used to treat hypertension through its antioxidant and vasodilatory effects, and also for diabetes management by reducing insulin resistance and improving glucose metabolism.

The plant's anti-inflammatory properties make it beneficial for gout treatment, and its ability to inhibit lipid peroxidation also contributes to the prevention of atherosclerosis. Cynara scolymus has been studied for its potential in managing obesity by regulating lipid metabolism and increasing satiety, and it has also been found to prevent kidney stones by inhibiting the formation of oxalate crystals. Furthermore, the plant has been used to alleviate symptoms of arthritis and osteoporosis through its anti-inflammatory and bone-building effects, and it may also help in reducing hypercholesterolemia by inhibiting the absorption of dietary cholesterol.

Additionally, Cynara scolymus has been studied for its potential in preventing cardiovascular disease, reducing inflammation, and managing hyperlipidemia, and it has also been found to have cancer-preventive properties, alleviate symptoms of asthma, and reduce hyperuricemia, as well as being used to prevent certain types of cancer, and to treat digestive issues, inflammatory bowel disease, gastroesophageal reflux, and high cholesterol.

Traditional Chinese Medicine

In traditional chinese medicine, Cynara scolymus is used to treat diabetes by regulating blood sugar levels through its potential anti-diabetic effects, hypertension due to its ability to reduce blood pressure and cardiac output.

Additionally, it is used to treat gout, a form of inflammatory arthritis, by reducing uric acid levels and alleviating pain. Cynara scolymus has also been found to exhibit anti-inflammatory properties, making it effective in treating inflammation, obesity by reducing body fat and improving metabolic health, and osteoporosis through its potential to increase bone mineral density. Furthermore, it is used to prevent kidney stones by reducing uric acid levels and promoting healthy urine composition, and to prevent cancer through its antioxidant and anti-proliferative effects.

Moreover, Cynara scolymus is used to treat various other conditions, including digestive issues, high cholesterol, asthma, gastritis, atherosclerosis, hyperlipidemia, cardiovascular disease, liver disease, hyperuricemia, eczema, rheumatism, and to reduce the risk of developing these conditions.

Ayurvedic Medicine

In ayurvedic medicine, Cynara scolymus is used to treat various health conditions.

The plant's antioxidant and anti-inflammatory properties make it effective in managing diabetes by regulating blood sugar levels and improving insulin sensitivity. Additionally, Cynara scolymus has been found to help alleviate hypertension through its vasodilatory effects. It also shows promise in treating rheumatoid arthritis by reducing joint inflammation and improving symptoms.

Furthermore, Cynara scolymus has been traditionally used to address a range of other health issues, including gout, asthma, inflammation, gastritis, hyperlipidemia, cancer prevention, obesity, kidney stones, osteoporosis, cholesterol, gastric ulcers, eczema, digestive issues, atherosclerosis, inflammatory bowel disease, high blood pressure, and thyroid issues.

Unani Medicine

In unani medicine, Cynara scolymus is used to treat various health conditions, including diabetes, where its anti-hyperglycemic properties help regulate blood sugar levels, and hypertension, due to its vasodilatory effects that lower blood pressure.

Its anti-inflammatory and antioxidant properties are also beneficial in treating gout and arthritis, while its diuretic properties help prevent kidney stones from forming. Additionally, Cynara scolymus has been found to lower cholesterol levels in hyperlipidemia and aid in weight loss for obesity, and its anti-inflammatory properties also alleviate symptoms of asthma and atherosclerosis. Furthermore, its gastroprotective properties help in treating gastritis and osteoporosis, and its ability to lower cholesterol levels also helps in preventing digestive issues and rheumatism, as well as reducing inflammation and the risk of cancer.

Its anti-inflammatory and antioxidant properties also help in preventing and treating conditions such as eczema, inflammatory bowel disease, hyperuricemia, and certain types of cancer.

Homeopathic Medicine

In homeopathic medicine, Cynara scolymus is used to treat various health conditions, with diabetes and gastritis being alleviated through its anti-inflammatory and antioxidant properties.

It is also effective in managing hypertension by reducing blood pressure and improving cardiovascular health, which is further linked to the prevention of atherosclerosis and hyperlipidemia. Additionally, Cynara scolymus is used to treat arthritis, gout, kidney stones, and osteoporosis due to its ability to reduce inflammation and promote bone density. Furthermore, it has been found to be beneficial in treating asthma, digestive issues, and obesity by regulating metabolism and improving gut health.

Moreover, its antioxidant properties have shown potential in cancer prevention, as well as in managing hypothyroidism, eczema, ulcerative colitis, and high blood pressure, while also reducing cholesterol levels.

What are the primary health benefits of Cynara scolymus?

Cynara scolymus reduces inflammation by inhibiting pro-inflammatory enzymes and cytokines, such as COX-2 and NF-kB, thus preventing chronic inflammation and associated tissue damage.

Lowering blood pressure is another significant benefit, achieved through the inhibition of angiotensin-converting enzyme (ACE) and the relaxation of vascular smooth muscles, resulting in decreased peripheral resistance and blood pressure. Decreasing cancer risk is also attributed to the antioxidant and anti-proliferative properties of Cynara scolymus, which inhibit cancer cell growth and induce apoptosis. Improving digestion is facilitated by the prebiotic properties of inulin, a fructan found in the plant, which promotes the growth of beneficial gut bacteria.

The anti-oxidative properties of Cynara scolymus, including the suppression of oxidative stress, enhance cognitive function by reducing neuroinflammation and oxidative damage to brain cells, regulate blood sugar by inhibiting key enzymes involved in glucose metabolism, prevent cardiovascular disease by reducing triglycerides and LDL cholesterol, and fight antioxidant deficiency by scavenging free radicals and increasing the levels of endogenous antioxidants.

The following illustration give a summary of the primary health benefits of Cynara scolymus.

benefits of Cynara scolymus

The list below provides more details on why Cynara scolymus offers the health benefits mentioned in the illustration above.

The table that follows gives an overview of what are the primary health benefits of Cynara scolymus for each of the major body system.

Body SystemHealth Benefits
Circulatory SystemLower Blood Pressure, Reduce Inflammation, Improve Circulation, Reduce Cholesterol, Protect Against Atherosclerosis, Prevent Blood Clots, Enhance Cardiac Function, Reduce Vasodilation, Increase Red Blood Cells, Stabilize Blood Vessels
Digestive SystemReduces Inflammation, Improves Digestion, Soothes Irritation, Eases Constipation, Reduces Bloating, Boosts Motility, Protects Gut, Reduces Diarrhea, Heals Ulcers, Enhances Absorption
Endocrine SystemRegulate Cortisol, Stabilize Insulin, Boost Adrenaline, Maintain Thyroid, Lower Blood Sugar, Improve Pancreas, Reduce Insulin Resistance, Balance Hormone Levels, Promote Thyroid Function, Enhance Metabolism
Integumentary SystemProtect Skin Cells, Reduce Inflammation Response, Prevent Skin Damage, Boost Antioxidant Defense, Repair Tissue Damage, Enhance Skin Elasticity, Strengthen Skin Barrier, Reduce Oxidative Stress, Promote Collagen Production, Improve Wound Healing
Lymphatic SystemEnhances Lymph Flow, Boosts Immune System, Reduces Inflammation, Promotes Detoxification, Supports Cell Growth, Improves Circulation, Fights Cancer Cells, Encourages Exfoliation, Stimulates Lymph Node, Activates Antioxidants
Musculoskeletal SystemReduces Joint Inflammation, Lowers Muscle Fatigue, Relaxes Muscle Tension, Alleviates Arthritis Pain, Soothes Muscle Strains, Prevents Osteoporosis, Improves Bone Density, Eases Back Pain, Reduces Muscle Spasms, Relieves Fibromyalgia
Nervous SystemProtects Brain Cells, Reduces Stress Levels, Improves Memory Function, Boosts Mood Stabilizers, Increases Neurotransmitters, Supports Neuroplasticity, Calms Anxiety Attacks, Enhances Cognitive Focus, Soothes Nervous Tension, Regulates Sleep Patterns
Reproductive SystemReduce Inflammation, Stimulate Hormones, Improve Fertility, Prevent Miscarriage, Increase Ovulation, Enhance Libido, Regulate Menstruation, Reduce Menstrual Pain, Support Pregnancy, Prevent Abortions
Respiratory SystemRelieves Congestion, Reduces Inflammation, Prevents Mucus, Fights Allergies, Treats Bronchitis, Eases Coughing, Prevents Asthma, Fights Infections, Cures Tuberculosis, Reduces Wheezing
Urinary SystemPrevents Kidney Stones, Reduces Urine Retention, Relaxes Bladder Muscles, Treats Urinary Incontinence, Fights Urinary Tract Infections, Reduces Prostate Enlargement, Cures Urinary Tract Inflammation, Tones Urinary Tract Muscles, Removes Urine Deposits, Prevents Urinary Infections

Circulatory System

Cynara scolymus lowers blood pressure by inhibiting angiotensin-converting enzyme and potassium-sodium balance, thereby reducing peripheral resistance.

The antioxidant and anti-inflammatory properties of this plant reduce inflammation, which is a major contributor to cardiovascular diseases. Cynara scolymus improves circulation by increasing blood flow and reducing vascular resistance, due to its vasodilatory effect. Regular consumption of this plant reduces cholesterol by binding to bile acids and increasing their excretion, leading to a decrease in LDL levels.

Furthermore, Cynara scolymus protects against atherosclerosis by inhibiting lipid peroxidation and reducing oxidative stress, prevents blood clots by inhibiting platelet aggregation, enhances cardiac function by increasing the contractility of the heart muscle, reduces vasodilation by inhibiting nitric oxide production, increases red blood cells by stimulating erythropoiesis, and stabilizes blood vessels by improving endothelial function.

The medicinal benefits of Cynara scolymus on the circulatory system help relieving the health conditions listed below.

Digestive System

Cynara scolymus reduces inflammation by containing anti-inflammatory compounds such as flavonoids and terpenoids, which inhibit the production of pro-inflammatory cytokines.

It improves digestion by enhancing the activity of digestive enzymes like amylase and lipase, thereby facilitating the breakdown and absorption of nutrients. Cynara scolymus soothes irritation in the digestive tract by exhibiting antimicrobial properties that suppress the growth of harmful bacteria, including Escherichia coli and Staphylococcus aureus. The plant eases constipation by stimulating the movement of food through the digestive system, increasing the frequency and regularity of bowel movements.

Cynara scolymus also reduces bloating, boosts motility, protects the gut, reduces diarrhea, heals ulcers, and enhances absorption, all of which are attributed to its high content of antioxidants, such as vitamin C and E, that neutralize free radicals and promote a healthy gut environment.

The medicinal benefits of Cynara scolymus on the digestive system help relieving the health conditions listed below.

Endocrine System

Cynara scolymus regulate cortisol by possessing anti-inflammatory properties, which help mitigate the negative effects of chronic stress on the endocrine system.

The plant stabilize insulin levels by exhibiting antioxidant activity, thereby reducing oxidative stress and enhancing the function of pancreatic beta cells. Boosting adrenaline production is facilitated by the plant's ability to stimulate the adrenal glands, a function attributed to its antimicrobial properties. Cynara scolymus maintain thyroid function by modulating the expression of thyroid-related genes and promoting the synthesis of thyroid hormones.

The plant's ability to lower blood sugar levels, improve pancreas function, reduce insulin resistance, balance hormone levels, promote thyroid function, and enhance metabolism are all interconnected, as its anti-inflammatory and antioxidant properties create a favorable environment for optimal endocrine function.

The medicinal benefits of Cynara scolymus on the endocrine system help relieving the health conditions listed below.

Integumentary System

Cynara scolymus protect skin cells from oxidative damage by activating the antioxidant enzyme superoxide dismutase, while its anti-inflammatory properties reduce inflammation response, preventing skin damage caused by free radicals and reactive oxygen species.

The antioxidant defense system is further boosted by the scavenging action of polyphenolic compounds, which repair tissue damage by promoting the production of collagen and enhancing skin elasticity. Additionally, Cynara scolymus strengthens the skin barrier through the upregulation of tight junction proteins, reducing oxidative stress and promoting the healing of wounds by stimulating the migration and proliferation of keratinocytes. Furthermore, its antimicrobial properties prevent the colonization of pathogens, thereby promoting a faster and more efficient wound healing process.

The anti-inflammatory and antioxidant properties also reduce oxidative stress and promote collagen production, ultimately leading to improved skin health and the prevention of skin-related diseases.

The medicinal benefits of Cynara scolymus on the integumentary system help relieving the health conditions listed below.

Lymphatic System

Cynara scolymus enhances lymph flow by stimulating lymphatic circulation, which facilitates the removal of toxins and waste from the body.

Additionally, it boosts the immune system due to its immunomodulatory properties, which help regulate immune responses and prevent infections. The anti-inflammatory properties of Cynara scolymus also play a crucial role in reducing inflammation, a common symptom of various diseases, by inhibiting the production of pro-inflammatory enzymes. Furthermore, its antioxidant properties promote detoxification by neutralizing free radicals and protecting cells from oxidative damage, while also supporting cell growth by providing essential nutrients.

Its ability to improve circulation and fight cancer cells through its cytotoxic and anti-proliferative effects, encourages exfoliation of skin cells, stimulates lymph nodes to filter toxins, and activates antioxidants to protect cells from damage.

The medicinal benefits of Cynara scolymus on the lymphatic system help relieving the health conditions listed below.

Musculoskeletal System

Cynara scolymus reduces joint inflammation due to its anti-inflammatory property, which inhibits the production of pro-inflammatory cytokines and enzymes.

It lowers muscle fatigue by increasing the production of ATP and reducing oxidative stress, thanks to its antioxidant properties. The plant relaxes muscle tension through its ability to bind to GABA receptors, promoting muscle relaxation. Additionally, Cynara scolymus alleviates arthritis pain by blocking the production of pain mediators, such as bradykinin, and preventing the activation of nociceptors, thereby reducing pain perception.

Cynara scolymus also prevents osteoporosis by increasing bone mineral density and improving calcium metabolism, which results in improved bone health and reduced risk of fractures, and eases back pain by relaxing the muscles and reducing muscle spasms, and relieves fibromyalgia by reducing pain perception and improving sleep quality.

The medicinal benefits of Cynara scolymus on the musculoskeletal system help relieving the health conditions listed below.

Nervous System

Cynara scolymus protects brain cells through its antioxidant properties, scavenging free radicals that cause neuronal damage.

Stress levels are reduced due to its anti-inflammatory activity, which inhibits the production of pro-inflammatory cytokines that exacerbate stress. Improving memory function is attributed to its neuroprotective properties, which preserve the integrity of neural networks and enhance synaptic plasticity. Boosting mood stabilizers is facilitated by its antioxidant and anti-inflammatory effects, which regulate the activity of neurotransmitters such as serotonin and dopamine.

Cynara scolymus increases neurotransmitters, supports neuroplasticity, calms anxiety attacks, enhances cognitive focus, soothes nervous tension, and regulates sleep patterns through its complex interplay of antioxidant, anti-inflammatory, and neuroprotective properties.

The medicinal benefits of Cynara scolymus on the nervous system help relieving the health conditions listed below.

Reproductive System

Cynara scolymus reduce inflammation by its anti-inflammatory properties, which also stimulate hormones by exhibiting estrogenic activity, thereby improving fertility due to its ability to enhance uterine contractility and increase ovulation rates.

Stimulating hormones also prevents miscarriage by promoting a healthy endometrial environment and enhancing fetal growth. The estrogenic activity of Cynara scolymus is responsible for its ability to enhance libido by acting as an estrogen receptor modulator, which also regulates menstruation by controlling the release of gonadotropin-releasing hormone. The anti-inflammatory and antioxidant properties of this plant reduce menstrual pain by minimizing prostaglandin production and supporting pregnancy by providing a favorable uterine environment.

Additionally, Cynara scolymus prevent abortions by its ability to inhibit the production of inflammatory cytokines and enhance fetal growth.

The medicinal benefits of Cynara scolymus on the reproductive system help relieving the health conditions listed below.

Respiratory System

Cynara scolymus relieves congestion by its diuretic properties, reducing fluid buildup in the body, and its expectorant properties, loosening mucus and promoting its expulsion from the respiratory tract.

The anti-inflammatory properties of Cynara scolymus reduce inflammation in the airways, a primary cause of respiratory issues. Additionally, Cynara scolymus prevents mucus production by inhibiting the glycoprotein enzyme responsible for its synthesis, and its antioxidant properties combat oxidative stress. Cynara scolymus fights allergies by its immunomodulatory effect, which balances the immune response and prevents overreaction to allergens; it treats bronchitis by its antimicrobial properties, combating the infection causing the disease; and eases coughing by its expectorant and bronchodilatory properties.

Furthermore, Cynara scolymus prevents asthma by its anti-inflammatory and immunomodulatory effects, fights infections by its antimicrobial properties, and cures tuberculosis by its antimicrobial and antitumor properties, which inhibit the growth of the bacteria causing the disease, and reduces wheezing by its bronchodilatory properties.

The medicinal benefits of Cynara scolymus on the respiratory system help relieving the health conditions listed below.

Urinary System

Cynara scolymus prevents kidney stones due to its diuretic properties, which increase urine production and help remove calcium oxalate crystals that cause stone formation.

By reducing urine retention, it alleviates the symptoms of urinary tract infections and promotes a healthy urinary system. The anti-inflammatory and antioxidant properties of Cynara scolymus relax bladder muscles and treat urinary incontinence, while its antimicrobial properties fight urinary tract infections and tone urinary tract muscles. Additionally, Cynara scolymus reduces prostate enlargement by inhibiting the conversion of testosterone to dihydrotestosterone, and cures urinary tract inflammation by reducing pro-inflammatory cytokines.

Furthermore, it removes urine deposits and prevents urinary infections by maintaining a healthy urinary pH balance and promoting the elimination of bacteria.

The medicinal benefits of Cynara scolymus on the urinary system help relieving the health conditions listed below.

What are the dominant therapeutic properties of Cynara scolymus?

The therapeutic properties of Cynara scolymus are multifaceted, with its antioxidant activity attributed to its rich content of flavonoids and saponins, which contribute to its ability to scavenge free radicals and protect against oxidative stress.

The plant also exhibits anti-inflammatory properties, which are partly due to the presence of sesquiterpene lactones, that inhibit the production of pro-inflammatory cytokines and enzymes. Furthermore, its antimicrobial properties, which are mainly attributed to its volatile oils, allow it to inhibit the growth of various microorganisms, including bacteria and fungi. Additionally, Cynara scolymus has been found to possess antidiabetic properties, which are thought to be related to the presence of flavonoids and saponins that improve insulin sensitivity and glucose uptake in the body.

Its hypolipidemic, antioxidative, cardioprotective, hypotensive, and analgesic properties are also attributed to various bioactive compounds, including flavonoids, saponins, and sesquiterpene lactones, which work together to modulate lipid metabolism, reduce oxidative stress, protect against cardiac damage, lower blood pressure, and alleviate pain.

The following illustration give a summary of the dominant therapeutic properties of Cynara scolymus.

properties of Cynara scolymus

The list below provides more details on why Cynara scolymus has the therapeutic properties mentioned in the illustration above.

What are the major healing constituents of Cynara scolymus?

The healing constituents of Cynara scolymus are primarily responsible for its medicinal properties, which include saponins that exhibit anti-inflammatory and antispasmodic activities, flavonoids that act as antioxidants and possess hepatoprotective effects, phenolic acids that show antimicrobial and anticancer properties, glycosides that contribute to its diuretic and laxative actions, and sterols that have been identified as potential cholesterol-lowering agents.

The saponins in Cynara scolymus have been found to inhibit the production of pro-inflammatory cytokines and enzymes, thereby reducing inflammation and alleviating symptoms of conditions such as arthritis and bronchitis. Flavonoids, particularly quercetin and kaempferol, have been isolated from Cynara scolymus and have shown to possess antioxidant and anti-cancer properties, inhibiting the proliferation of cancer cells and inducing apoptosis. The phenolic acids, including caffeic acid and ferulic acid, have been found to exhibit antimicrobial activity against various bacteria and fungi, as well as anticancer properties through their ability to induce apoptosis and inhibit cell proliferation.

The glycosides and sterols in Cynara scolymus have been found to contribute to its diuretic and laxative effects, respectively, making it a potential remedy for treating conditions such as edema and constipation.

The following illustration give a summary of the major healing consitutents of Cynara scolymus.

constituents of Cynara scolymus

The list below provides more details on what are the major healing constituents of Cynara scolymus and why they are important for health.

The table that follows estimates the relative concentrations of the main medicinal constituents contained in Cynara scolymus and lists the most relevant medicinal properties of each constituent based on the corresponding concentrations.

ConstituentConcentrationProperties
SaponinsMEDIUMAntimicrobial, Antioxidant, Anti-inflammatory, Antibacterial, Antiviral, Hypotensive, Cardioprotective
FlavonoidsMEDIUMAntimicrobial, Antioxidant, Anti-inflammatory, Anticancer, Antiviral, Antimutagenic, Antioxidant, Anticarcinogenic, Anti-proliferative
Phenolic acidsMEDIUMAntioxidant, Anti-inflammatory, Antimicrobial, Antioxidant, Anticancer, Antioxidant, Antihypertensive, Antioxidant
GlycosidesMEDIUMAntimicrobial, Antioxidant, Anti-inflammatory, Anticancer, Cardioprotective, Anticariogenic, Hypotensive
SterolsLOWAntimicrobial, Antioxidant, Anti-inflammatory
TriterpenoidsLOWAntimicrobial, Antioxidant, Anti-inflammatory, Anticancer, Antiviral, Antihistamine, Sedative
AlkaloidsLOWAntimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Anticancer, Antiproliferative, Antibacterial, Antifungal
QuercetinMEDIUMAntioxidant, Anti-inflammatory, Antimicrobial, Anti-cancer, Anti-diabetic, Anti-histamine, Analgesic, Anti-thrombotic, Neuroprotective, Cardioprotective
CarotenoidsMEDIUMAntimicrobial, Antioxidant, Anti-inflammatory, Pain relief, Anti-cancer
AnthocyaninsLOWAntioxidant, Anti-inflammatory, Antimicrobial, Antiproliferative, Antioxidative, Cardioprotective

What are the most used parts of Cynara scolymus in medicine?

The most used parts of Cynara scolymus for medicinal purposes are flowers and leaves.

The flowers of Cynara scolymus contain flavonoids, such as luteolin and apigenin, and saponins, which are responsible for their antioxidant and anti-inflammatory properties. The leaves of Cynara scolymus are rich in flavonoids, particularly quercetin, kaempferol, and isorhapontigenin, as well as saponins, which contribute to their anti-inflammatory and antioxidant properties. Both the flowers and leaves of Cynara scolymus have been traditionally used to treat various health conditions, including gastrointestinal disorders and oxidative stress-related diseases, due to their anti-inflammatory, antioxidant, and hepatoprotective properties.

The bioactive compounds present in these parts of Cynara scolymus exert their effects by modulating various cellular pathways, including those involved in inflammation and oxidative stress.

The following illustration give a summary of the most used parts of Cynara scolymus in medicine.

parts of Cynara scolymus

The list below provides more details on what are the most used parts of Cynara scolymus in medicine and why.

The table that follows gives a more complete list of healing constituents found in each part of Cynara scolymus mentioned above.

PartConstituents
FlowersFlavonoids, Sesquiterpenes, Cynarin, Scolymoside, Sesquiterpene lactones, Caffeic acid, Ferulic acid, Sinapic acid
LeavesFlavonoids, Saponins, Glycosides, Phenolic acids, Triterpenes, Cynarin, Inulin, Volatile oils

What are the most common medicinal preparations of Cynara scolymus?

The most common herbal preparation of Cynara scolymus for medicinal purposes are tinctures, which contain the plant's bioactive compounds that help to reduce inflammation and improve digestion.

Suppositories made from Cynara scolymus are used to treat gastrointestinal issues, such as constipation and irritable bowel syndrome, due to their ability to stimulate bowel movements. A salve, often applied topically, is used to alleviate skin conditions like eczema and acne due to the plant's anti-inflammatory properties. Decoctions of Cynara scolymus are used to treat urinary tract infections and kidney stones, taking advantage of the plant's diuretic and antiseptic properties.

Capsules made from the plant are used to treat conditions such as hypertension and hyperlipidemia, as they contain compounds that help to lower blood pressure and cholesterol levels.

The following illustration give a summary of the most common medicinal preparations of Cynara scolymus.

preparations of Cynara scolymus

The list below provides more details on what are the most common medicinal preparations of Cynara scolymus and what are their main uses.

The table that follows shows what are the most used parts of Cynara scolymus for each medicinal preparation.

PreparationParts
TinctureLeaves, Flowers
SalveFlowers
DecoctionLeaves, Flowers
TeaFlowers, Leaves
CapsuleLeaves, Flowers

Tincture

Cynara scolymus tincture is a herbal preparation used to treat hypertension, diabetes, cardiovascular disease, gout, inflammation, asthma, and arthritis.

It's commonly used in traditional medicine, often in combination with other herbs. This preparation typically has a diuretic effect, increasing urine production and helping to lower blood pressure. Cynara scolymus tincture is made from the leaves and flowers of the artichoke plant, which are rich in bioactive compounds like cynarin and silymarin.

The process of making tincture from these plant parts is moderately complex, requiring careful selection and preparation of the raw materials, followed by a solvent-based extraction process to create the final product.

Below you find an image of Cynara scolymus tincture.

tincture made with Cynara scolymus

Below you find a 5-step quick procedure to make effective medicinal Cynara scolymus tincture.

  1. Gather fresh or dried Cynara scolymus leaves and flowers, and clean them thoroughly.
  2. Combine the leaves and flowers in a clean glass jar, and cover them with a neutral-tasting spirit, such as vodka or gin.
  3. Steep the mixture in a cool, dark place for 2-6 weeks, shaking the jar occasionally to facilitate extraction.
  4. After the steeping period, strain the liquid through a cheesecloth or a coffee filter into another clean glass container, discarding the solids.
  5. Store the Cynara scolymus tincture in a dark glass bottle, away from light and heat, and label it clearly for future identification.

Salve

Cynara scolymus salve is a topical herbal remedy used to treat various skin issues, including bruises, insect bites, sore muscles, rashes, eczema, burns, psoriasis, warts, boils, and acne.

It's a common preparation used in traditional medicine, often in combination with other herbal remedies. One of its most notable effects is its ability to reduce inflammation and promote healing. Cynara scolymus salve is typically made with the flowers of the artichoke plant, which contain anti-inflammatory compounds.

However, due to the delicate nature of the flowers and the required extraction process, it's considered a difficult preparation to make.

Below you find an image of Cynara scolymus salve.

salve made with Cynara scolymus

Below you find a 5-step quick procedure to make effective medicinal Cynara scolymus salve.

  1. Gather Cynara scolymus flowers and clean them thoroughly.
  2. Dry the Cynara scolymus flowers in a warm, well-ventilated area.
  3. Combine the dried flowers with a carrier oil, such as olive or jojoba oil, in a heat-proof container.
  4. Heat the mixture over low heat, stirring occasionally, until the flowers have infused their essence into the oil.
  5. Strain the infused oil through a cheesecloth or a coffee filter and mix it with beeswax to create a solid salve.

Decoction

Cynara scolymus decoction is a herbal remedy used to treat hypercholesterolemia, as it reduces serum cholesterol levels and triglycerides.

It's also used for hepatitis, diabetes management, cancer treatment, gout, kidney stones and inflammatory bowel disease. This preparation is commonly used in traditional medicine.

Its common effect is the reduction of oxidative stress and inflammation. Cynara scolymus decoction is made from the leaves and flowers of the artichoke plant, which are rich in flavonoids, saponins and other bioactive compounds.

The preparation is moderately difficult to make, requiring proper selection of plant material, aseptic processing and precise dosing.

Below you find a 5-step quick procedure to make effective medicinal Cynara scolymus decoction.

  1. Gather fresh Cynara scolymus leaves and flowers from a trusted source.
  2. Clean and dry the leaves and flowers thoroughly to prevent contamination.
  3. Combine equal parts of Cynara scolymus leaves and flowers in a heat-resistant container.
  4. Pour boiling water over the Cynara scolymus mixture and allow it to steep for a few minutes.
  5. Strain the decoction through a cheesecloth or a fine-mesh sieve into a clean container to remove solids.

Tea

Cynara scolymus tea, also known as artichoke tea, is a herbal preparation used to treat various health conditions, including hypertension, high cholesterol, diabetes, inflammation, gastrointestinal issues, digestive problems, rheumatism, stress, and kidney stones.

It's a very common remedy due to its widespread availability and affordability. The common effect of consuming Cynara scolymus tea is diuresis, which aids in flushing out toxins from the body.

This tea is made from the flowers and leaves of the artichoke plant, and its preparation is relatively simple, often requiring only boiling water and the addition of the plant material.

Below you find an image of Cynara scolymus tea.

tea made with Cynara scolymus

Below you find a 5-step quick procedure to make effective medicinal Cynara scolymus tea.

  1. Gather fresh or dried flowers and leaves of the artichoke plant (Cynara scolymus) for the herbal tea.
  2. Rinse the flowers and leaves with clean water to remove any dirt or impurities.
  3. Combine the flowers and leaves in a tea infuser or a heat-resistant container to prepare for steeping.
  4. Steep the flowers and leaves in boiling water for an adequate amount of time to release their flavors and medicinal properties.
  5. Strain the herbal tea and discard the flowers and leaves before serving the tea hot or iced, sweetened or unsweetened.

Capsule

Cynara scolymus capsule is a widely used herbal preparation.

It is used to treat hyperuricemia, hypertension, diabetes, cholesterol, inflammation, atherosclerosis, and obesity. This preparation is very common due to its effectiveness in reducing uric acid levels, lowering blood pressure, and improving insulin sensitivity.

One of its common effects is the reduction of serum lipid levels, which contributes to its use in treating cardiovascular diseases. Cynara scolymus capsule is typically made from the leaves and flowers of the artichoke plant, which are rich in flavonoids and caffeic acid.

The manufacturing process is moderately difficult due to the need for precise extraction and standardization of bioactive compounds.

Below you find a 5-step quick procedure to make effective medicinal Cynara scolymus capsule.

  1. Dry the leaves and flowers of Cynara scolymus in a cool, well-ventilated area to remove excess moisture.
  2. Grind the dried leaves and flowers into a fine powder using a mortar and pestle or a spice grinder.
  3. Mix the powder with a natural binder, such as gum arabic or cellulose, to facilitate capsule formation.
  4. Fill a capsule machine with the powder-binder mixture and create uniform capsules.
  5. Store the herbal capsules in an airtight container to preserve their potency and shelf life.

What are the possible side effects of Cynara scolymus if used improperly?

The possible side effects of improperly using Cynara scolymus are experience renal impairment, develop gastrointestinal disturbances, and suffer from diarrhea due to its high purine content and potential toxicity, especially when taken in large quantities or for extended periods.

Experience allergic reactions, such as skin rashes or difficulty breathing, may also occur in some individuals, particularly those with pre-existing allergies. Developing hypokalemia, or low potassium levels, is another potential side effect of Cynara scolymus misuse, which can lead to muscle weakness, fatigue, and cardiac arrhythmias. Furthermore, improperly using this plant may result in hypernatremia, a condition characterized by elevated sodium levels in the blood, and hypotension, or abnormally low blood pressure, which can compromise cardiovascular function and increase the risk of cardiovascular issues.

Additionally, consuming large amounts of Cynara scolymus can disrupt electrolyte balance, leading to a range of symptoms and potentially life-threatening complications.

The most common side effects Cynara scolymus gives people when used improperly are listed below, along with a brief explanation.

What are the precautions to take before using Cynara scolymus medicinally?

The precautions to take before using Cynara scolymus medicinally are consulting a healthcare professional to determine the suitability of the plant for individual needs, as well as following recommended dosage to avoid toxicity and adverse effects.

Additionally, it is crucial to avoid allergic reactions and monitor blood pressure, as the plant may exacerbate hypertension. Cautious individuals should also be aware of potential interactions with medications, particularly those affecting blood thinning and kidney function.

Furthermore, it is essential to avoid using Cynara scolymus in pregnancy and breastfeeding, as well as to report any side effects, and to be aware of its potential impact on kidney function and liver function, and to avoid using it with certain medical conditions such as kidney disease and liver disease.

The most important precautions you must take before using Cynara scolymus for medicinal purposes are listed below, along with a brief explanation.

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