By Leen Randell
Updated: Jul 21, 2024
Curcuma longa has some side effects when used improperly, such as stomach upset, diarrhea, and nausea.
These side effects are often caused by consuming high doses of the herb, particularly when taken in supplement form. In severe cases, they can worsen people's lives, causing dehydration, electrolyte imbalances, and even kidney stones.
Furthermore, individuals with pre-existing gastrointestinal conditions, such as ulcers or inflammatory bowel disease, may experience exacerbated symptoms.
This article explains in details the 10 most common side effects of Curcuma longa if used imporperly.
Curcuma longa causes allergic reactions in some individuals due to its molecular structure, which contains a compound called curcumin.
This compound is responsible for the spice's vibrant yellow color and potent antioxidant properties, but it can also trigger an immune response in sensitive people, leading to symptoms such as hives, itching, and rashes.
The exact mechanism of this allergic reaction is not fully understood, but it may be related to the similarity between curcumin and certain proteins found in the body.
Curcuma longa triggers digestive issues due to its high concentration of curcuminoids, which can irritate the stomach lining and alter the natural balance of gut bacteria.
The bioactive compound, curcumin, has been shown to reduce prostaglandins, hormone-like substances that regulate digestion, potentially leading to symptoms such as bloating, gas, and abdominal pain.
Additionally, turmeric's potent anti-inflammatory properties may exacerbate existing digestive conditions like irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD).
Curcuma longa induces kidney damage due to its high concentration of curcuminoids, which can cause oxidative stress and inflammation in the kidneys.
Additionally, the spice's ability to inhibit certain enzymes involved in glutathione metabolism may further exacerbate kidney damage.
Furthermore, long-term consumption of Curcuma longa may lead to a buildup of reactive oxygen species (ROS) in the body, which can damage renal tissue and potentially cause chronic kidney disease.
Curcuma longa increases risk of bleeding due to its ability to thin blood and inhibit platelet aggregation.
This is because curcumin, a key compound in turmeric, interferes with the body's natural clotting mechanism, making it more likely for wounds to bleed excessively or take longer to stop bleeding.
Additionally, turmeric may also interact with anticoagulant medications, further increasing the risk of bleeding complications.
Curcuma longa produces stomach ulcers due to its high content of curcuminoids, which can irritate the mucous membranes in the digestive tract.
The bioactive compound curcumin has been shown to inhibit the production of prostaglandins, naturally occurring hormones that help protect the stomach lining from acidic secretions, leading to increased susceptibility to ulcers.
This irritation can cause inflammation and erosion of the stomach lining, resulting in the formation of ulcers.
Curcuma longa interferes with iron absorption by inhibiting the action of ferroportin, a protein responsible for releasing iron from enterocytes into the bloodstream.
This can lead to reduced levels of hemoglobin in the blood and anemia.
Additionally, curcumin, a bioactive compound found in Curcuma longa, may also reduce iron uptake by blocking the activity of divalent metal transporter 1 (DMT1), further exacerbating iron deficiency.
Curcuma longa disrupts thyroid function due to its potential to interact with thyroid hormones.
The active compound curcumin in turmeric may bind to thyroid hormone receptors, altering their activity and leading to changes in thyroid function. Additionally, turmeric's anti-inflammatory properties could exacerbate hypothyroidism or Hashimoto's disease by suppressing the immune system, which is already compromised in these conditions.
This interference with thyroid regulation may lead to symptoms such as fatigue, weight gain, or mood changes.
Curcuma longa inhibits blood clotting due to its ability to interfere with platelet aggregation and reduce thromboxane A2 production.
This is because curcuminoids, the active compounds in Curcuma longa, have a direct effect on the blood vessels, causing them to relax and dilate.
As a result, it may take longer for wounds to heal and individuals may be more prone to bleeding or bruising when taking Curcuma longa supplements regularly.
Curcuma longa causes liver inflammation due to its ability to stimulate the production of certain enzymes in the liver.
The curcuminoids present in Curcuma longa can increase the levels of these enzymes, leading to increased detoxification and metabolism.
This can result in an inflammatory response within the liver, potentially causing liver damage or scarring over time.
Curcuma longa affects glucose levels.
This is due to its potential to lower blood sugar levels by stimulating insulin production and improving insulin sensitivity. Additionally, curcumin, a key compound in Curcuma longa, has been shown to inhibit the activity of enzymes involved in glucose absorption, thereby reducing the amount of glucose available for uptake into the bloodstream.
As a result, individuals with diabetes or those taking medications that regulate blood sugar levels may need to monitor their glucose levels closely when using Curcuma longa supplements.