Blackdot
Cullen corylifolium · Accepted scientific name
Scientific literature: Very Extensive (579 studies) · ★★★★★
Blackdot, scientifically known as Cullen corylifolium, is a medicinal herb belonging to the Apiaceae family. Widely used in traditional Ayurvedic medicine, it is prized for its bioactive compounds, particularly psoralens. This plant is primarily recognized for its potential therapeutic benefits in treating skin conditions like psoriasis and vitiligo.
Names and Synonyms
Common Names
- Blackdot
- Indian Bread Root
- Malaysian Scurfpea
- Scurfy Pea
- scurfy-pea
Scientific Names
Accepted name
Cullen corylifoliumSynonyms
- Lotodes corylifolium
- Bipontinia corylifolia
- Dorychnium corylifolium
- Lotodes corylifolium var. parvifolium
- Psoralea corylifolia
- Psoralea patersoniae
- Trifolium unifolium
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified within the phylum Streptophyta and the class Equisetopsida. It is further categorized under the subclass Magnoliidae and the order Fabales, placing it in the family Fabaceae. Finally, it is identified by its genus, Cullen, and its specific species name, corylifolium.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Fabales |
| Family | Fabaceae |
| Genus | Cullen |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a widespread presence across several key regions in Africa and the Indian Ocean. In Northeast Tropical Africa, it can be found inhabiting the landscapes of Djibouti, Somalia, and the island of Socotra. Its distribution extends significantly into the Western Indian Ocean as well. Specifically, the species is documented growing on the island of Mauritius. Furthermore, its range reaches the island of Réunion, completing its unique geographical footprint.
| Region | Area |
|---|---|
| Northeast Tropical Africa | Djibouti |
| Northeast Tropical Africa | Socotra |
| Northeast Tropical Africa | Somalia |
| Western Indian Ocean | Mauritius |
| Western Indian Ocean | Réunion |
| Western Asia | Iraq |
| Arabian Peninsula | Oman |
| Arabian Peninsula | Yemen |
| China | China South-Central |
| Indian Subcontinent | Assam |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Ecology
The ecology of Cullen corylifolium is strictly defined by its preference for high-altitude montane environments, where it thrives within a specific vertical niche. This species is primarily found in specialized mountain ecosystems, occupying an elevational range that begins at a minimum of 1500 m AMSL and extends to a maximum of 1920 m AMSL. This narrow altitudinal band suggests that the plant is adapted to the unique climatic conditions, such as cooler temperatures, higher UV exposure, and specific moisture regimes, characteristic of these mid-to-high mountain zones. Such precise ecological constraints indicate that its distribution is heavily dependent on the stable environmental parameters provided by this specific elevation gradient.
- Elevational range max:
- 1920 m AMSL
- Elevational range min:
- 1500 m AMSL
Life history
The life history of Cullen corylifolium is characterized by its status as a perennial plant, allowing it to persist through multiple growing seasons. Throughout its biological cycle, the plant undergoes various developmental stages, exhibiting a lifecycle that can be classified as variable depending on environmental conditions and resource availability. As a perennial species, it establishes a robust root system that enables it to survive dormant periods, eventually re-emerging to undergo seasonal vegetative growth and reproductive phases. This longevity supports its ability to produce flowers and seeds over several years, contributing to its long-term presence within its natural habitat.
- Lifecycle :
- perennial
Morphology
The morphology of Cullen corylifolium is characterized by a growth form categorized as both a herb and a forb, manifesting a non-woody structure. It typically reaches an average plant height of approximately 0.6 m. The plant is terrestrial in its habitat, functioning as an independent organism rather than a parasite or an epiphyte. In terms of its physical habit, it is a self-supporting species, lacking the climbing mechanisms of a liana or vine.
- Aquatic :
- terrestrial
- Climber :
- self-supporting
- Epiphyte :
- terrestrial
- Growth form :
- herb
- Growth form :
- forb
- Parasite :
- independent
- Plant height mean:
- 0.6 m
- Woodiness :
- non-woody
Physiology
The physiology of Cullen corylifolium is characterized by a C3 photosynthetic pathway, which involves the direct fixation of carbon dioxide through the Calvin cycle within the mesophyll cells. In addition to its carbon assimilation mechanisms, the plant functions as a nitrogen fixer, utilizing symbiotic relationships to convert atmospheric nitrogen into a bioavailable form to support its metabolic processes and growth.
- Nitrogen fixer :
- yes
- Photosynthetic pathway :
- C3
Reproduction
The reproduction of Cullen corylifolium is driven by a biotic pollination syndrome, relying primarily on insects to facilitate the transfer of pollen. This insect-mediated process ensures genetic exchange through biological vectors rather than abiotic factors like wind or water. Following successful fertilization, the plant produces seeds characterized by a highly uniform mass; both the minimum, maximum, and mean seed mass are recorded at precisely 0.01762 g. This consistency in seed weight suggests a stabilized reproductive output per seed produced by the species.
- Pollination syndrome :
- insect
- Pollination syndrome :
- biotic
- Seed mass mean:
- 0.01762 g
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Cullen corylifolium has 3 reported plant parts identified across 14 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include seed, fruit, leaf.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Seed | 10 supporting sources | ★★★★★ |
| Fruit | 2 supporting sources | ★☆☆☆☆ |
| Leaf | 2 supporting sources | ★☆☆☆☆ |
Seed
- Planta medica
- Archives of pharmacal research
- Natural product research
- Frontiers in pharmacology
- Reviews in the neurosciences
View 5 additional sources
- Pharmacognosy magazine
- Fitoterapia
- F1000Research
- Antimicrobial agents and chemotherapy
- Phytomedicine : international journal of phytotherapy and phytopharmacology
Fruit
- BMC complementary and alternative medicine
- Toxicology reports
Leaf
- Journal of alternative and complementary medicine (New York, N.Y.)
- F1000Research
Chemicals
Cullen corylifolium has 102 reported phytochemicals identified across 14 scientific publications and several other databases. The most consistently reported chemicals include Psoralen, Bakuchiol, ISOPSORALEN, Psoralidin, Neobavaisoflavone.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Psoralen | 17 supporting sources | ★★★★★ |
| Bakuchiol | 14 supporting sources | ★★★★★ |
| ISOPSORALEN | 10 supporting sources | ★★★★★ |
| Psoralidin | 10 supporting sources | ★★★★★ |
| Neobavaisoflavone | 6 supporting sources | ★★★☆☆ |
| Bavachinin | 5 supporting sources | ★★★☆☆ |
| Corylin | 5 supporting sources | ★★★☆☆ |
| Coumarins | 5 supporting sources | ★★★☆☆ |
| Flavonoids | 4 supporting sources | ★★☆☆☆ |
| daidzein | 4 supporting sources | ★★☆☆☆ |
Psoralen
- Dr. Duke
- Plant science : an international journal of experimental plant biology
- Fitoterapia
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Toxicology reports
View 12 additional sources
- Molecules (Basel, Switzerland)
- International journal of radiation biology
- Nutrients
- Archives of pharmacal research
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Yao xue xue bao = Acta pharmaceutica Sinica
- Current pharmaceutical design
- International journal of molecular sciences
- Pharmaceutical biology
- Chemistry & biodiversity
- Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
- Phytomedicine : international journal of phytotherapy and phytopharmacology
Bakuchiol
- Dr. Duke
- Oncotarget
- Plant science : an international journal of experimental plant biology
- Fitoterapia
- Journal of ethnopharmacology
View 9 additional sources
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Indian journal of biochemistry & biophysics
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Journal of clinical biochemistry and nutrition
- Planta medica
- Natural product research
- Journal of natural products
- F1000Research
- Antimicrobial agents and chemotherapy
ISOPSORALEN
- Dr. Duke
- Plant science : an international journal of experimental plant biology
- Fitoterapia
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Toxicology reports
View 5 additional sources
- Molecules (Basel, Switzerland)
- Nutrients
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Yao xue xue bao = Acta pharmaceutica Sinica
Psoralidin
- Dr. Duke
- Pharmacological reports : PR
- Fitoterapia
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Yao xue xue bao = Acta pharmaceutica Sinica
View 5 additional sources
- Reviews in the neurosciences
- International journal of molecular sciences
- Planta medica
- Archives of pharmacal research
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
Neobavaisoflavone
- Dr. Duke
- Pharmacological reports : PR
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- International journal of molecular sciences
- Planta medica
View 1 additional sources
- Journal of natural products
Bavachinin
- Dr. Duke
- Fitoterapia
- International immunopharmacology
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Planta medica
Corylin
- Dr. Duke
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Infectious disorders drug targets
- Planta medica
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
Coumarins
- Chemistry & biodiversity
- Phytotherapy research : PTR
- Frontiers in pharmacology
- The American journal of Chinese medicine
- Ayu
Flavonoids
- Phytotherapy research : PTR
- Frontiers in pharmacology
- The American journal of Chinese medicine
- Ayu
daidzein
- Dr. Duke
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- International journal of molecular sciences
- Journal of natural products
Activities
Cullen corylifolium has 285 reported activities identified across 14 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Anticancer, Antitumor, Antibacterial, Antimicrobial.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Antioxidant | 8 supporting sources | ★★★★☆ |
| Anticancer | 5 supporting sources | ★★★☆☆ |
| Antitumor | 5 supporting sources | ★★★☆☆ |
| Antibacterial | 4 supporting sources | ★★☆☆☆ |
| Antimicrobial | 4 supporting sources | ★★☆☆☆ |
| Estrogenic | 3 supporting sources | ★★☆☆☆ |
| Antidepressant | 2 supporting sources | ★☆☆☆☆ |
| Antiviral | 2 supporting sources | ★☆☆☆☆ |
| Chemopreventive | 2 supporting sources | ★☆☆☆☆ |
| Cytotoxic | 2 supporting sources | ★☆☆☆☆ |
Antioxidant
- Dr. Duke
- Fitoterapia
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Scientific reports
- Chinese medicine
View 3 additional sources
- Journal of clinical biochemistry and nutrition
- Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
- F1000Research
Anticancer
- Dr. Duke
- Journal of alternative and complementary medicine (New York, N.Y.)
- Pharmaceutical biology
- Chemistry & biodiversity
- Molecules (Basel, Switzerland)
Antitumor
- Dr. Duke
- Pharmacological reports : PR
- Fitoterapia
- The American journal of Chinese medicine
- Chinese medicine
Antibacterial
- Dr. Duke
- Fitoterapia
- Chinese medicine
- Molecules (Basel, Switzerland)
Antimicrobial
- Dr. Duke
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- The American journal of Chinese medicine
- F1000Research
Estrogenic
- Dr. Duke
- The American journal of Chinese medicine
- Journal of ethnopharmacology
Antidepressant
- Dr. Duke
- The American journal of Chinese medicine
Antiviral
- Dr. Duke
- F1000Research
Chemopreventive
- Dr. Duke
- Pharmacological reports : PR
Cytotoxic
- Dr. Duke
- Archives of pharmacal research
Medicinal Uses
Cullen corylifolium has 1 reported medicinal uses identified across 14 scientific publications and several other databases. The most consistently reported uses include Vitiligo.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| Vitiligo | Planta medica (and other 1 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| seeds | Archives of pharmacal research (and other 3 sources) | ★★☆☆☆ |
| 70% EtOH extracts | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| An ethanol extract | Journal of natural products (and other 1 sources) | ★☆☆☆☆ |
| Aqueous extracts | Phytomedicine : international journal of phytotherapy and phytopharmacology (and other 1 sources) | ★☆☆☆☆ |
| Leigong's method | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (and other 1 sources) | ★☆☆☆☆ |
| PSC extract | Annals of dermatology (and other 1 sources) | ★☆☆☆☆ |
| Polysaccharides | Frontiers in immunology (and other 1 sources) | ★☆☆☆☆ |
| Psoralea corylifolia seed | Reviews in the neurosciences (and other 1 sources) | ★☆☆☆☆ |
| Psoralidin (PSO) | Chinese medicine (and other 1 sources) | ★☆☆☆☆ |
| bakuchiol | Journal of clinical biochemistry and nutrition (and other 1 sources) | ★☆☆☆☆ |