purging croton

Croton tiglium · Accepted scientific name

Scientific literature: Extensive (173 studies) · ★★★★☆

Purging croton, scientifically known as Croton tiglium, is a potent medicinal plant native to Southeast Asia. Renowned for its powerful purgative properties, it contains croton oil, traditionally used to treat intestinal ailments. While effective in controlled doses, its intense laxative effects require careful handling to avoid severe toxicity.

Family
Euphorbiaceae
Native range
Asia-Temperate
Parts used
Seed · Leaf
Common names
Purging Croton
Scientific synonyms
Tiglium Officinale · Halecus Verus · 17 more

Names and Synonyms

Common Names

Scientific Names

Accepted name

Croton tiglium

Synonyms

Regional and Traditional Names

Spanish:

  • Tiglium subincanum
  • Oxydectes birmanica
  • Oxydectes blancoana
  • Crotoncillo
  • Oxydectes pavana
  • Croton camaza
  • Croton birmanicus
  • Croton officinalis
  • Croton himalaicus
  • Tiglium officinale
  • Tiglium cumingii
  • Croton muricatus
  • Halecus verus
  • Croton jamalgota
  • Tiglium lanceolatum
  • Oxydectes tiglium
  • croton

German:

  • Krotonölbaum
  • Purgierkroton

French:

  • Croton cathartique
  • Tiglium subincanum
  • Oxydectes birmanica
  • Oxydectes blancoana
  • Oxydectes pavana
  • Croton camaza
  • Croton birmanicus
  • Croton officinalis
  • Croton himalaicus
  • Tiglium cumingii
  • Tiglium officinale
  • Halecus verus
  • Croton jamalgota
  • Tiglium lanceolatum
  • Oxydectes tiglium
  • croton cathartique

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. It is further classified within the order Malpighiales and the family Euphorbiaceae. Ultimately, the medicinal species is identified by its genus, Croton.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Malpighiales
Family Euphorbiaceae
Genus Croton

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a specific geographical range across various regions of East Asia. Within China, its presence is noted in the South-Central, Southeast, and Hainan areas. The species also extends its distribution to the island of Taiwan. Furthermore, its habitat encompasses parts of Eastern Asia, specifically including Japan. Together, these locations define the natural footprint of Croton tiglium.

Region Area
China China South-Central
China Hainan
China China Southeast
Eastern Asia Japan
Eastern Asia Taiwan
Indian Subcontinent Assam
Indian Subcontinent Bangladesh
Indian Subcontinent East Himalaya
Indian Subcontinent India
Indian Subcontinent Maldives

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Life history

The life history of Croton tiglium is characterized by its status as a perennial species, ensuring its long-term presence within its natural ecosystem. As a phanerophyte, the plant maintains its photosynthetic organs well above the ground, typically developing into a robust woody structure. While its growth habit can be classified under the broader scope of nanophanerophyte traits in certain developmental stages or specific environmental contexts, it primarily functions as a significant woody plant. Furthermore, the species exhibits a deciduous nature, undergoing seasonal shedding of its foliage as part of its biological cycle.

Deciduousness :
deciduous
Life form :
nanophanerophyte
Life form :
phanerophyte
Lifecycle :
perennial

Morphology

The morphology of Croton tiglium is characterized by a woody growth form that manifests as both a tree and a shrub. As a terrestrial species, it is an independent organism that does not function as a parasite or an epiphyte. The plant is self-supporting rather than acting as a climber, liana, or vine. In terms of stature, it reaches a height ranging from a minimum of 3 m to a maximum of 6 m, with an average plant height of approximately 5.75 m.

Aquatic :
terrestrial
Climber :
self-supporting
Epiphyte :
terrestrial
Growth form :
tree
Growth form :
shrub
Parasite :
independent
Plant height max:
6 m
Plant height mean:
5.75 m
Plant height min:
3 m
Woodiness :
woody

Physiology

The physiological profile of Croton tiglium is characterized by a C3 photosynthetic pathway, indicating its metabolic reliance on the standard Calvin cycle for carbon fixation. The plant's vegetative structure features ovate leaves that lack both thorns and spines. These leaves exhibit significant morphological variation in size, with lengths ranging from a minimum of 7 cm to a maximum of 12 cm, maintaining a mean length of approximately 9.5 cm. The width of the foliage is similarly variable, spanning from 3 cm to a maximum of 7 cm, with an average width of 5 cm. The leaf margins are distinctly finely toothed, contributing to the overall leaf architecture. Additionally, the plant does not function as a nitrogen fixer, relying instead on external soil nutrient availability for its nitrogen requirements.

Leaf form :
ovate
Leaf length max:
12 cm
Leaf length mean:
9.5 cm
Leaf length min:
7 cm
Leaf margin :
finely toothed
Leaf spines :
no
Leaf thorns :
no
Leaf width max:
7 cm
Leaf width mean:
5 cm
Leaf width min:
3 cm
Nitrogen fixer :
no
Photosynthetic pathway :
C3

Reproduction

The reproduction of Croton tiglium is characterized by its specific inflorescence and fruit development patterns. The plant produces inflorescences that vary in size, ranging from a minimum length of 0.08 m to a maximum of 0.2 m. Following pollination, the development of the fruit is marked by consistent dimensions in length, with both the minimum, mean, and maximum fruit length recorded at 0.2 cm. However, the fruit width exhibits more variability, with a minimum width of 1.4 cm, a mean width of 1.7 cm, and a maximum width reaching 2 cm. The resulting seeds are highly uniform in mass, with a recorded mean, minimum, and maximum seed mass of 0.2179 g, ensuring a consistent reproductive output per seed.

Fruit length max:
0.2 cm
Fruit width max:
2 cm
Fruit width mean:
1.7 cm
Fruit width min:
1.4 cm
Inflorescence length max:
0.2 m
Inflorescence length min:
0.08 m
Seed mass mean:
0.2179 g

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Croton tiglium has 2 reported plant parts identified across 5 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include seed, leaf.

Plant parts reported in Croton tiglium
Plant part Supporting sources Consensus
Seed 4 supporting sources ★★☆☆☆
Leaf 1 supporting sources ★☆☆☆☆

Seed

  1. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
  2. Chemical & pharmaceutical bulletin
  3. Phytochemistry
  4. Ancient science of life

Leaf

  1. Phytochemical analysis : PCA

Chemicals

Croton tiglium has 38 reported phytochemicals identified across 5 scientific publications and several other databases. The most consistently reported chemicals include 12-o-acetylphorbol-13-decanoate, 12-O-Tetradecanoylphorbol 13-acetate, AMYLASE, Arachidic acid, Ash.

Chemicals reported in Croton tiglium
Chemical Supporting sources Consensus
12-o-acetylphorbol-13-decanoate 3 supporting sources ★★☆☆☆
12-O-Tetradecanoylphorbol 13-acetate 1 supporting sources ★☆☆☆☆
AMYLASE 1 supporting sources ★☆☆☆☆
Arachidic acid 1 supporting sources ★☆☆☆☆
Ash 1 supporting sources ★☆☆☆☆
CROTONIC ACID 1 supporting sources ★☆☆☆☆
Crotin 1 supporting sources ★☆☆☆☆
Crotonoside 1 supporting sources ★☆☆☆☆
FAT 1 supporting sources ★☆☆☆☆
Fatty acids 1 supporting sources ★☆☆☆☆

12-o-acetylphorbol-13-decanoate

  1. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
  2. Chemical & pharmaceutical bulletin
  3. Phytochemistry

12-O-Tetradecanoylphorbol 13-acetate

  1. Phytochemistry

AMYLASE

  1. Dr. Duke

Arachidic acid

  1. Dr. Duke

Ash

  1. Dr. Duke

CROTONIC ACID

  1. Ancient science of life

Crotin

  1. Dr. Duke

Crotonoside

  1. Dr. Duke

FAT

  1. Dr. Duke

Fatty acids

  1. The Journal of pharmacy and pharmacology

Activities

Croton tiglium has 108 reported activities identified across 5 scientific publications and several other databases. The most consistently reported activities include Analgesic, Antibacterial, Antitumor, 5-Alpha-Reductase-Inhibitor, Acaricide.

Activities reported in Croton tiglium
Activity Supporting sources Consensus
Analgesic 2 supporting sources ★☆☆☆☆
Antibacterial 2 supporting sources ★☆☆☆☆
Antitumor 2 supporting sources ★☆☆☆☆
5-Alpha-Reductase-Inhibitor 1 supporting sources ★☆☆☆☆
Acaricide 1 supporting sources ★☆☆☆☆
Acidulant 1 supporting sources ★☆☆☆☆
Allergenic 1 supporting sources ★☆☆☆☆
Alpha-Reductase-Inhibitor 1 supporting sources ★☆☆☆☆
Anemiagenic 1 supporting sources ★☆☆☆☆
AntiAIDS 1 supporting sources ★☆☆☆☆

Analgesic

  1. Dr. Duke
  2. The Journal of pharmacy and pharmacology

Antibacterial

  1. Dr. Duke
  2. The Journal of pharmacy and pharmacology

Antitumor

  1. Dr. Duke
  2. The Journal of pharmacy and pharmacology

5-Alpha-Reductase-Inhibitor

  1. Dr. Duke

Acaricide

  1. Dr. Duke

Acidulant

  1. Dr. Duke

Allergenic

  1. Dr. Duke

Alpha-Reductase-Inhibitor

  1. Dr. Duke

Anemiagenic

  1. Dr. Duke

AntiAIDS

  1. Dr. Duke

Conditions

Croton tiglium has 12 reported investigations on conditions identified across 5 scientific publications and several other databases. The most consistently reported conditions include constipation, HIV-1, analgesic, breast cancer, cancer.

Conditions investigated for Croton tiglium
Condition Supporting sources Consensus
Constipation 2 supporting sources ★☆☆☆☆
Hiv-1 1 supporting sources ★☆☆☆☆
Analgesic 1 supporting sources ★☆☆☆☆
Breast cancer 1 supporting sources ★☆☆☆☆
Cancer 1 supporting sources ★☆☆☆☆
Defecation 1 supporting sources ★☆☆☆☆
Gastrointestinal diseases 1 supporting sources ★☆☆☆☆
Headache 1 supporting sources ★☆☆☆☆
Nasopharyngeal carcinoma 1 supporting sources ★☆☆☆☆
Pain 1 supporting sources ★☆☆☆☆

Constipation

  1. Current pharmaceutical biotechnology
  2. Ancient science of life

Hiv-1

  1. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan

Analgesic

  1. The Journal of pharmacy and pharmacology

Breast cancer

  1. Gene

Cancer

  1. Current drug targets

Defecation

  1. The Journal of pharmacy and pharmacology

Gastrointestinal diseases

  1. The Journal of pharmacy and pharmacology

Headache

  1. The Journal of pharmacy and pharmacology

Nasopharyngeal carcinoma

  1. Biomedical and environmental sciences : BES

Pain

  1. Phytotherapy research : PTR

Preparations

Croton tiglium has 2 reported preparations identified across 5 scientific publications and several other databases. The most consistently reported preparations include MeOH extract, seeds.

Preparations reported for Croton tiglium
Preparation Supporting sources Consensus
Meoh extract 1 supporting sources ★☆☆☆☆
Seeds 1 supporting sources ★☆☆☆☆

Meoh extract

  1. Phytochemistry

Seeds

  1. Chemical & pharmaceutical bulletin