mulangu

Croton macrostachyus · Accepted scientific name

Scientific literature: Sparse (96 studies) · ★★☆☆☆

Mulaングu, scientifically known as Croton macrostachyus, is a versatile medicinal plant highly valued in traditional healing practices. Renowned for its diverse pharmacological properties, it is frequently utilized to treat various ailments, including inflammation and infections. This study explores its bioactive compounds and therapeutic potential in modern herbal medicine.

Family
Euphorbiaceae
Native range
Africa
Parts used
Leaf · Root
Common names
Mulangu · Mulugu · 1 more
Scientific synonyms
Oxydectes Macrostachya · Rottlera Schimperi · 3 more

Names and Synonyms

Common Names

Scientific Names

Accepted name

Croton macrostachyus

Synonyms

Regional and Traditional Names

Spanish:

  • Croton acuminatus
  • Croton butaguensis
  • Croton guerzesiensis
  • Croton macrostachyus var. mollissimus
  • Oxydectes macrostachya
  • Rottlera schimperi

French:

  • Croton butaguensis
  • Croton guerzesiensis
  • Oxydectes macrostachya
  • Rottlera schimperi

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and the class Equisetopsida. Within the subclass Magnoliidae, it follows the order Malpighiales and is a member of the family Euphorbiaceae. Specifically, its taxonomic identity is defined by the genus Croton, which includes the species Croton macrostachyus.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Malpighiales
Family Euphorbiaceae
Genus Croton

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant is primarily located within the West Tropical Africa region. Specifically, its range includes the country of Ghana, where it can be found growing in native habitats. It is also distributed across the coastal and inland areas of Guinea. Furthermore, the species extends its presence into the Ivory Coast and Liberia. Finally, its geographical reach concludes with documented occurrences in Nigeria.

Region Area
West Tropical Africa Ghana
West Tropical Africa Guinea
West Tropical Africa Ivory Coast
West Tropical Africa Liberia
West Tropical Africa Nigeria
West-Central Tropical Africa Burundi
West-Central Tropical Africa Central African Republic
West-Central Tropical Africa Cameroon
West-Central Tropical Africa Rwanda
West-Central Tropical Africa DR Congo

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Life history

The life history of Croton macrostachys is characterized by its status as a perennial plant, allowing it to persist through multiple growing seasons. As a phanerophyte, its regenerative buds are located high above the ground on woody stems, a structural adaptation that defines its primary life form. This species exhibits a deciduous nature, shedding its foliage periodically as part of its seasonal developmental cycle.

Deciduousness :
deciduous
Life form :
phanerophyte
Lifecycle :
perennial

Morphology

The morphology of Croton macrostachyus is characterized by its robust growth form, primarily existing as a woody tree. This species is a terrestrial plant that functions as an independent organism, rather than acting as a parasite or an epiphyte. In terms of stature, it is a significant structural component of its environment, with a plant height that typically ranges from a minimum of 3 m to a maximum of approximately 15.24 m, maintaining an average height of around 17.5 m. Although it possesses a sturdy, woody structure, it is categorized as a self-supporting plant rather than a climber, liana, or vine.

Aquatic :
terrestrial
Climber :
self-supporting
Epiphyte :
terrestrial
Growth form :
tree
Parasite :
independent
Plant height max:
15.24018532 m
Plant height mean:
17.5 m
Plant height min:
3 m
Woodiness :
woody

Physiology

The physiology of Croton macrostachyus is characterized by a standard C3 photosynthetic pathway, meaning it utilizes the Calvin cycle to fix carbon dioxide through the enzyme Rubisco without the specialized anatomical adaptations found in C4 or CAM plants. In terms of nutrient cycling and metabolic processes, this species does not function as a nitrogen fixer, lacking the symbiotic relationship with diazotrophic bacteria required to convert atmospheric nitrogen into usable forms for the plant.

Nitrogen fixer :
no
Photosynthetic pathway :
C3

Reproduction

The reproduction of Croton macrostachyus is characterized by a biotic pollination strategy, specifically relying on insect vectors, with bees playing a significant role in the process. The plant exhibits an absence of self-fertilization, necessitating cross-pollination to ensure genetic diversity. Following successful fertilization, the plant produces fruits categorized under the "other" type, which maintain a consistent average dimension of 1 cm in both length and width. The resulting seeds vary in mass, ranging from a minimum of 0.04 g to a maximum of 0.086 g, with an overall mean seed mass of approximately 0.0607 g. For dispersal, the species utilizes a zoochorous syndrome, specifically employing endozoochory, where seeds are dispersed through the internal passage of animals to facilitate colonization of new habitats.

Dispersal syndrome :
zoochorous
Dispersal syndrome :
endozoochorous
Fruit length mean:
1 cm
Fruit type :
other
Fruit width mean:
1 cm
Pollination syndrome :
insect
Pollination syndrome :
bee
Pollination syndrome :
biotic
Seed mass max:
0.086 g
Seed mass mean:
0.060706667 g
Seed mass min:
0.04 g
Self fertilization :
absent

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Croton macrostachyus has 3 reported plant parts identified across 14 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include leaf, root, seed.

Plant parts reported in Croton macrostachyus
Plant part Supporting sources Consensus
Leaf 8 supporting sources ★★★★☆
Root 5 supporting sources ★★★☆☆
Seed 1 supporting sources ★☆☆☆☆

Leaf

  1. BMC complementary and alternative medicine
  2. TheScientificWorldJournal
  3. Evidence-based complementary and alternative medicine : eCAM
  4. Journal of parasitology research
  5. Chemistry & biodiversity
View 3 additional sources
  1. BMC veterinary research
  2. Malaria journal
  3. Heliyon

Root

  1. Evidence-based complementary and alternative medicine : eCAM
  2. BMC chemistry
  3. Journal of experimental pharmacology
  4. Heliyon
  5. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine

Seed

  1. Scientific reports

Chemicals

Croton macrostachyus has 28 reported phytochemicals identified across 14 scientific publications and several other databases. The most consistently reported chemicals include Flavonoids, Tannins, Terpenoids, FE, MN.

Chemicals reported in Croton macrostachyus
Chemical Supporting sources Consensus
Flavonoids 3 supporting sources ★★☆☆☆
Tannins 3 supporting sources ★★☆☆☆
Terpenoids 3 supporting sources ★★☆☆☆
FE 2 supporting sources ★☆☆☆☆
MN 2 supporting sources ★☆☆☆☆
Anthraquinones 1 supporting sources ★☆☆☆☆
Ash 1 supporting sources ★☆☆☆☆
CA 1 supporting sources ★☆☆☆☆
CHROMIUM 1 supporting sources ★☆☆☆☆
COPPER 1 supporting sources ★☆☆☆☆

Flavonoids

  1. BMC chemistry
  2. Evidence-based complementary and alternative medicine : eCAM
  3. Journal of parasitology research

Tannins

  1. TheScientificWorldJournal
  2. Journal of parasitology research
  3. Evidence-based complementary and alternative medicine : eCAM

Terpenoids

  1. Evidence-based complementary and alternative medicine : eCAM
  2. Chemistry & biodiversity
  3. Journal of parasitology research

FE

  1. BMC plant biology
  2. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine

MN

  1. BMC plant biology
  2. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine

Anthraquinones

  1. Evidence-based complementary and alternative medicine : eCAM

Ash

  1. BMC plant biology

CA

  1. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine

CHROMIUM

  1. Biological trace element research

COPPER

  1. Biological trace element research

Activities

Croton macrostachyus has 11 reported activities identified across 14 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Antibacterial, Anthelmintic, Anticancer, Anticonvulsant.

Activities reported in Croton macrostachyus
Activity Supporting sources Consensus
Antioxidant 3 supporting sources ★★☆☆☆
Antibacterial 2 supporting sources ★☆☆☆☆
Anthelmintic 1 supporting sources ★☆☆☆☆
Anticancer 1 supporting sources ★☆☆☆☆
Anticonvulsant 1 supporting sources ★☆☆☆☆
Antidiabetic 1 supporting sources ★☆☆☆☆
Antifungal 1 supporting sources ★☆☆☆☆
Antiplasmodial 1 supporting sources ★☆☆☆☆
Bacteriostatic 1 supporting sources ★☆☆☆☆
Hepatoprotective 1 supporting sources ★☆☆☆☆

Antioxidant

  1. BMC chemistry
  2. Evidence-based complementary and alternative medicine : eCAM
  3. Journal of experimental pharmacology

Antibacterial

  1. BMC chemistry
  2. Evidence-based complementary and alternative medicine : eCAM

Anthelmintic

  1. Evidence-based complementary and alternative medicine : eCAM

Anticancer

  1. Evidence-based complementary and alternative medicine : eCAM

Anticonvulsant

  1. Epilepsy & behavior : E&B

Antidiabetic

  1. Evidence-based complementary and alternative medicine : eCAM

Antifungal

  1. Evidence-based complementary and alternative medicine : eCAM

Antiplasmodial

  1. Evidence-based complementary and alternative medicine : eCAM

Bacteriostatic

  1. TheScientificWorldJournal

Hepatoprotective

  1. Journal of experimental pharmacology

Conditions

Croton macrostachyus has 21 reported investigations on conditions identified across 14 scientific publications and several other databases. The most consistently reported conditions include malaria, wounds, Escherichia coli, HIV, Klebsiella pneumoniae.

Conditions investigated for Croton macrostachyus
Condition Supporting sources Consensus
Malaria 5 supporting sources ★★★☆☆
Wounds 2 supporting sources ★☆☆☆☆
Escherichia coli 1 supporting sources ★☆☆☆☆
Hiv 1 supporting sources ★☆☆☆☆
Klebsiella pneumoniae 1 supporting sources ★☆☆☆☆
Mycobacterium tuberculosis 1 supporting sources ★☆☆☆☆
Pseudomonas aeruginosa 1 supporting sources ★☆☆☆☆
Staphylococcus aureus 1 supporting sources ★☆☆☆☆
Abdominal pains 1 supporting sources ★☆☆☆☆
Cancer 1 supporting sources ★☆☆☆☆

Malaria

  1. FEMS microbes
  2. Evidence-based complementary and alternative medicine : eCAM
  3. BMC research notes
  4. Journal of ethnopharmacology
  5. Malaria journal

Wounds

  1. Evidence-based complementary and alternative medicine : eCAM
  2. Chemistry & biodiversity

Escherichia coli

  1. Scientific reports

Hiv

  1. Current HIV research

Klebsiella pneumoniae

  1. Scientific reports

Mycobacterium tuberculosis

  1. BMC complementary and alternative medicine

Pseudomonas aeruginosa

  1. Scientific reports

Staphylococcus aureus

  1. Evidence-based complementary and alternative medicine : eCAM

Abdominal pains

  1. Evidence-based complementary and alternative medicine : eCAM

Cancer

  1. Evidence-based complementary and alternative medicine : eCAM

Preparations

Croton macrostachyus has 24 reported preparations identified across 14 scientific publications and several other databases. The most consistently reported preparations include aqueous fraction, chloroform fraction, crude extract, 80% methanolic extracts, Croton macrostachyus honey.

Preparations reported for Croton macrostachyus
Preparation Supporting sources Consensus
Aqueous fraction 2 supporting sources ★☆☆☆☆
Chloroform fraction 2 supporting sources ★☆☆☆☆
Crude extract 2 supporting sources ★☆☆☆☆
80% methanolic extracts 1 supporting sources ★☆☆☆☆
Croton macrostachyus honey 1 supporting sources ★☆☆☆☆
Decoctions 1 supporting sources ★☆☆☆☆
Methanol crude extract/fractions of leaves 1 supporting sources ★☆☆☆☆
Absolute methanol 1 supporting sources ★☆☆☆☆
Aqueous methanol/ethanol (1 : 1) leaf extracts 1 supporting sources ★☆☆☆☆
Crude methanolic extract of leaves 1 supporting sources ★☆☆☆☆

Aqueous fraction

  1. BMC complementary and alternative medicine
  2. Journal of experimental pharmacology

Chloroform fraction

  1. BMC complementary and alternative medicine
  2. Journal of experimental pharmacology

Crude extract

  1. BMC complementary and alternative medicine
  2. Journal of experimental pharmacology

80% methanolic extracts

  1. BMC complementary and alternative medicine

Croton macrostachyus honey

  1. Saudi journal of biological sciences

Decoctions

  1. Epilepsy & behavior : E&B

Methanol crude extract/fractions of leaves

  1. Malaria journal

Absolute methanol

  1. Asian Pacific journal of tropical biomedicine

Aqueous methanol/ethanol (1 : 1) leaf extracts

  1. Chemistry & biodiversity

Crude methanolic extract of leaves

  1. Journal of parasitology research