Sangre de Grado
Croton lechleri · Accepted scientific name
Scientific literature: Very Extensive (367 studies) · ★★★★★
Sangre de Grado, scientifically known as Croton leclyceri, is a remarkable medicinal plant native to the Amazon rainforest. Renowned for its deep red, latex-like sap, it possesses potent healing properties. Traditionally used to treat wounds, inflammation, and infections, this botanical treasure remains a cornerstone of natural holistic medicine.
- Family
- Euphorbiaceae
- Native range
- Southern America
- Parts used
- Leaf
- Common names
- Dragon'S Blood · Dragon'S-Blood Croton
- Scientific synonyms
- Oxydectes Lechleri · Croton Draco Var. Cordatus
Names and Synonyms
Common Names
- dragon's blood
- dragon's-blood croton
Scientific Names
Accepted name
Croton lechleriSynonyms
- Oxydectes lechleri
- Croton draco var. cordatus
Regional and Traditional Names
Spanish:
- sangre de drago
- sangre de dragón
- sangre de grado
French:
- Oxydectes lechleri
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and the phylum Streptophyta, situated within the class Equisetopsida and subclass Magnoliidae. It is classified under the order Malpighiales and the family Euphorbiaceae. Ultimately, its taxonomic identity is defined by its placement in the genus Croton.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Malpighiales |
| Family | Euphorbiaceae |
| Genus | Croton |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant, known as Croton lechleri, is found across several regions in Western South America. Its natural habitat encompasses the diverse landscapes of Colombia, where it thrives in tropical environments. The species is also widely distributed throughout the country of Ecuador. Furthermore, its range extends into the territory of Peru, contributing to its regional importance. Finally, this medicinal plant can be found growing within the borders of Bolivia.
| Region | Area |
|---|---|
| Western South America | Bolivia |
| Western South America | Colombia |
| Western South America | Ecuador |
| Western South America | Peru |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Ecology
The ecology of Croton lechleri is characterized by its specific adaptation to the Campo de Várzea habitat, where it thrives within these specialized grassland ecosystems. This species occupies a distinct altitudinal niche, maintaining an elevational range that begins at 370 m AMSL and extends up to a maximum of 700 m AMSL.
- Elevational range max:
- 700 m AMSL
- Elevational range min:
- 370 m AMSL
- Habitat :
- Campo de Várzea
Life history
The life history of Croton lechleri is characterized by its nature as a perennial species, allowing it to establish a long-term presence within its tropical ecosystem. As a perennial, the plant does not complete its life cycle within a single growing season or two, but rather undergoes continuous development, often reaching significant structural maturity over many years. This longevity enables the plant to endure seasonal fluctuations and contribute consistently to its habitat through sustained growth and repeated reproductive cycles. Throughout its extended lifespan, the plant maintains its physiological functions, moving through various stages of vegetative expansion and periodic flowering, which ensures its long-term survival and ability to propagate within its native environment.
- Lifecycle :
- perennial
Morphology
The morphology of Croton lechleri is characterized by its robust, woody growth form, specifically developing as a tree. As a self-supporting organism, it does not function as a climber or a liana, nor does it exhibit parasitic behavior, maintaining an independent lifestyle. The plant is strictly terrestrial, lacking any epiphytic qualities such as hemi-epiphytic or facultative epiphytic stages. In terms of stature, it reaches significant dimensions, with an average plant height of approximately 12 meters and a maximum recorded height of up to 18 meters.
- Aquatic :
- terrestrial
- Climber :
- self-supporting
- Epiphyte :
- terrestrial
- Growth form :
- tree
- Parasite :
- independent
- Plant height max:
- 18 m
- Plant height mean:
- 12 m
- Woodiness :
- woody
Physiology
The physiology of Croton lechleri is characterized by a C3 photosynthetic pathway, a standard mechanism for many tropical woody species that involves the direct fixation of carbon dioxide through the Calvin cycle. In terms of its nutrient acquisition strategies, the plant does not function as a nitrogen fixer, meaning it relies on the absorption of nitrates and ammonium from the soil through its root system rather than establishing symbiotic relationships with nitrogen-fixing bacteria to convert atmospheric nitrogen.
- Nitrogen fixer :
- no
- Photosynthetic pathway :
- C3
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Croton lechleri has 1 reported plant parts identified across 2 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include leaf.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Leaf | 2 supporting sources | ★☆☆☆☆ |
Leaf
- Journal of ethnopharmacology
- Journal of natural products
Chemicals
Croton lechleri has 59 reported phytochemicals identified across 2 scientific publications and several other databases. The most consistently reported chemicals include Taspine, (+)-Gallocatechin, (+)-catechin, (-)-Epicatechin, (-)-Epigallocatechin.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Taspine | 3 supporting sources | ★★☆☆☆ |
| (+)-Gallocatechin | 1 supporting sources | ★☆☆☆☆ |
| (+)-catechin | 1 supporting sources | ★☆☆☆☆ |
| (-)-Epicatechin | 1 supporting sources | ★☆☆☆☆ |
| (-)-Epigallocatechin | 1 supporting sources | ★☆☆☆☆ |
| 1,3,5-Trimethoxybenzene | 1 supporting sources | ★☆☆☆☆ |
| 2,4,6-Trimethoxyphenol | 1 supporting sources | ★☆☆☆☆ |
| 3',4-O-Dimethylcedrusin | 1 supporting sources | ★☆☆☆☆ |
| 3,4-DIMETHOXYPHENOL | 1 supporting sources | ★☆☆☆☆ |
| 4-Hydroxyphenethyl alcohol | 1 supporting sources | ★☆☆☆☆ |
Taspine
- Dr. Duke
- Journal of ethnopharmacology
- Journal of pharmaceutical sciences
(+)-Gallocatechin
- Dr. Duke
(+)-catechin
- Dr. Duke
(-)-Epicatechin
- Dr. Duke
(-)-Epigallocatechin
- Dr. Duke
1,3,5-Trimethoxybenzene
- Dr. Duke
2,4,6-Trimethoxyphenol
- Dr. Duke
3',4-O-Dimethylcedrusin
- Dr. Duke
3,4-DIMETHOXYPHENOL
- Dr. Duke
4-Hydroxyphenethyl alcohol
- Dr. Duke
Activities
Croton lechleri has 276 reported activities identified across 2 scientific publications and several other databases. The most consistently reported activities include Antitumor, Analgesic, Anticancer, Antioxidant, Antiviral.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Antitumor | 3 supporting sources | ★★☆☆☆ |
| Analgesic | 2 supporting sources | ★☆☆☆☆ |
| Anticancer | 2 supporting sources | ★☆☆☆☆ |
| Antioxidant | 2 supporting sources | ★☆☆☆☆ |
| Antiviral | 2 supporting sources | ★☆☆☆☆ |
| Cytotoxic | 2 supporting sources | ★☆☆☆☆ |
| (-)-Chronotropic | 1 supporting sources | ★☆☆☆☆ |
| (-)-Inotropic | 1 supporting sources | ★☆☆☆☆ |
| 5-Lipoxygenase-Inhibitor | 1 supporting sources | ★☆☆☆☆ |
| ACE-Inhibitor | 1 supporting sources | ★☆☆☆☆ |
Antitumor
- Dr. Duke
- Journal of ethnopharmacology
- Planta medica
Analgesic
- Dr. Duke
- The Journal of investigative dermatology
Anticancer
- Dr. Duke
- Journal of ethnopharmacology
Antioxidant
- Dr. Duke
- Dermatologic therapy
Antiviral
- Dr. Duke
- Dermatologic therapy
Cytotoxic
- Dr. Duke
- Journal of ethnopharmacology
(-)-Chronotropic
- Dr. Duke
(-)-Inotropic
- Dr. Duke
5-Lipoxygenase-Inhibitor
- Dr. Duke
ACE-Inhibitor
- Dr. Duke
Medicinal Uses
Croton lechleri has 13 reported medicinal uses identified across 2 scientific publications and several other databases. The most consistently reported uses include cancer, cancers, edema, granuloma, itching.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| cancer | Journal of ethnopharmacology (and other 2 sources) | ★☆☆☆☆ |
| cancers | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| edema | The Journal of investigative dermatology (and other 1 sources) | ★☆☆☆☆ |
| granuloma | Journal of pharmaceutical sciences (and other 1 sources) | ★☆☆☆☆ |
| itching | The Journal of investigative dermatology (and other 1 sources) | ★☆☆☆☆ |
| melanoma | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| neurogenic inflammation | The Journal of investigative dermatology (and other 1 sources) | ★☆☆☆☆ |
| pain | The Journal of investigative dermatology (and other 1 sources) | ★☆☆☆☆ |
| tumor | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| vasorelaxation | The Journal of investigative dermatology (and other 1 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| sap | Phytomedicine : international journal of phytotherapy and phytopharmacology (and other 2 sources) | ★☆☆☆☆ |
| "Sangre de Drago" | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| cortex | PloS one (and other 1 sources) | ★☆☆☆☆ |
| extracts | Acta odontologica latinoamericana : AOL (and other 1 sources) | ★☆☆☆☆ |
| plant crude extracts | Pharmacognosy magazine (and other 1 sources) | ★☆☆☆☆ |
| red sap | Phytomedicine : international journal of phytotherapy and phytopharmacology (and other 1 sources) | ★☆☆☆☆ |
| red viscous latex | Journal of natural products (and other 1 sources) | ★☆☆☆☆ |
| resin | Planta medica (and other 1 sources) | ★☆☆☆☆ |
| wound healing latex "sangre de grado" | Journal of natural products (and other 1 sources) | ★☆☆☆☆ |