Crepidiastrum sonchifolium
Crepidiastrum sonchifolium · Accepted scientific name
Scientific literature: Very Sparse (2 studies) · ★☆☆☆☆
Crepidiastrum sonchifolium is a plant of significant pharmacological interest due to its potent antitumor and antiviral activities. Research indicates that its chemical profile is rich in bioactive compounds, including sesquiterpenes, triterpenes, artemisinin, and paclitaxel. These substances demonstrate therapeutic potential against conditions such as hepatocellular carcinoma, liver cancer, and various viral infections, while also influencing vasoconstriction. Studies involving various preparations, such as the dried form or IsE at dosages of 10-160 g x L(-1), highlight its medicinal versatility. Consequently, this species remains a vital subject for developing targeted treatments for complex diseases.
- Synonyms
- Ixeris Denticulata Subsp. Sonchifolia · Ixeris Sonchifolia · 4 more
- Common names
- Not available
- Family
- Asteraceae
- Distribution
- Not available
- Plant Parts
- Not available
Classification
Common Names
Crepidiastrum sonchifolium is a versatile plant known by a diverse array of names across different cultures and languages. In English-speaking regions, it is frequently referred to by the descriptive common name sonchus-leaf crepidiastrum. Its linguistic reach extends into East Asia, where it is identified as jian lie jia huan yang shen, 抱莖小苦蕒, or イヌヤクシソウ. In Russian contexts, the species is recognized by its specific local designation, Крепидиаструм осотолистный. This wide variety of nomenclature highlights the plant's widespread presence and its importance in various global traditions.
Sources: Catalogue of Life (COL)
Synonyms
Crepidiastrum sonchifolium is a plant species that has been known by several different botanical names throughout history. Scientific literature frequently lists various synonyms for this taxon, including Ixeridium sonchifolium and Ixeris sonchifolia. It has also been classified under the names Ixeris denticulata subsp. sonchifolia and Paraixeris sonchifolia. Furthermore, the species was once identified as Lactuca denticulata var. sonchifolia in older taxonomic records. Understanding these various nomenclatural relationships is essential for accurate identification and study within the botanical community.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Crepidiastrum sonchifolium belongs to the vast kingdom Plantae, marking its place among the world's diverse vegetation. Within this kingdom, it is classified under the class Equisetopsida, representing a significant branch of vascular plants. The species is further organized into the order Asterales, a group known for its distinctive floral characteristics. It falls under the genus Crepidiastrum, which helps botanists identify its specific evolutionary lineage. Finally, its placement within the family Asteraceae connects it to a wide array of well-known flowering plants.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Asterales |
| Family | Asteraceae |
| Genus | Crepidiastrum |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Crepidiastrum sonchifolium is a plant species primarily found within the Asia-Temperate region. Its geographical reach is extensive across China, spanning from the North-Central provinces to the Southeast. The species is also well-documented throughout the South-Central territories of the country. Furthermore, its natural habitat extends into the northern reaches of Inner Mongolia. Finally, the plant maintains a notable presence in the Manchuria region, completing its broad distribution pattern.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Crepidiastrum sonchifolium is a distinctive herb characterized by its self-supporting growth form. This plant typically maintains a modest stature, with heights ranging from a minimum of 0.07 meters to a maximum of 1 meter. Depending on its specific environmental conditions, it often stabilizes at an average height of approximately 0.53 meters. Such variability in size allows the species to adapt effectively to its local habitat. Overall, its structural simplicity makes it a resilient addition to various ecological landscapes.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Crepidiastrum sonchifolium, also known by its synonym Ixeris sonchifolia, is a widely distributed medicinal plant recognized for its diverse pharmacological properties. Recent scientific investigations have highlighted its significant antitumor activity, specifically demonstrating its ability to promote apoptosis in hepatocellular carcinoma cells. Research suggests this effect is achieved by inhibiting the PI3K/AKT signaling pathway, offering promising potential for liver cancer treatment. Beyond its anticancer capabilities, the plant has also been documented to possess notable antiviral activities. These combined therapeutic characteristics underscore the plant's importance in both traditional medicine and modern pharmacological research.
Compounds
Crepidiastrum sonchifolium, also known by its synonym Ixeris sonchifolia, is a medicinal plant recognized for its diverse chemical profile. Research indicates that the plant contains significant amounts of sesquiterpenes and triterpenes, which contribute to its various pharmacological activities. These compounds are part of a broader group of terpenoids that serve as the plant's primary antitumor substances. Notably, the chemical constituents of this species include important bioactive molecules such as artemisinin and paclitaxel. Due to these potent properties, the plant shows great promise in modern research regarding cancer treatment and chemoprevention.
Conditions
Crepidiastrum sonchifolium, also known as Ixeris sonchifolia, demonstrates significant anticancer effects through its various chemical constituents. Research indicates that isolated compounds from the plant effectively treat A375, Hela, and L929 tumor cell lines via cytotoxic activity. Furthermore, the plant's sesquiterpene lactones have been shown to treat A549 human non-small cell lung cancer cells with potency comparable to established chemotherapeutic drugs. These biological activities highlight the plant's potential in targeting diverse malignant cell lines in vitro. Consequently, the medicinal value of the plant is closely tied to its ability to exert these specific anticancer actions.
Preparations
Crepidiastrum sonchifolium is prepared as a concentration of 10-160 g x L(-1) to observe its effects on the isometric tension of rat thoracic aortic rings. This plant is also prepared as Ixeris sonchifolia extract (IsE) to investigate its ability to induce apoptosis in hepatocellular carcinoma cells via the PI3K/AKT pathway. Additionally, the plant is utilized in its dried form as a component of traditional and folk medicines across various Asian countries. These different preparations allow researchers to study its diverse pharmacological activities, ranging from vasoconstriction mechanisms to anticancer potential. Through these specific forms, the medicinal properties of the species are comprehensively evaluated in both vascular and oncological studies.