logo of terrawhisper

Updated: Oct 22, 2024

What to know about Corydalis yanhusuo before using it medicinally

Corydalis yanhusuo plant

Corydalis yanhusuo, commonly known as yanhusuo, is an herb used in traditional Chinese medicine to treat various health conditions, including pain, inflammation, and anxiety disorders.

Its main medicinal uses include the treatment of arthritis, muscle spasms, and menstrual cramps. The herb has been shown to have several health benefits, including reducing inflammation, improving sleep quality, and exerting antioxidant effects. Corydalis yanhusuo's main therapeutic properties include analgesic, anti-inflammatory, and anxiolytic activities, which are attributed to its bioactive compounds.

In traditional herbal preparations, Corydalis yanhusuo is often combined with other herbs to make a decoction, known as "yanhusuo tang," which is used to relieve pain and promote relaxation.

The following article explains in detail what are the medicinal uses of Corydalis yanhusuo, its health benefits, therapeutic properties, bioactive compounds, used parts, and herbal preparation. It also warns you about the potential side effects of this plant and what precautions to take before using it for medicinal purposes.

ARTICLE SUMMARY: The table below summarizes the most crucial information about Corydalis yanhusuo provided in the article below, which is useful if you are in a hurry and don't have time to dig deep into the very detailed content that follows.

Medicinal AspectSummary
UsesArthritis, Anxiety, Stroke, Depression, Epilepsy, Chronic pain, Migraine, Inflammation, Pain, Neuropathy
BenefitsReduces inflammation, Relieves anxiety, Improves sleep, Enhances cognitive, Decreases pain, Supports immune, Boosts energy, Relieves depression, Improves digestion, Antioxidant properties
PropertiesAnalgesic, Antioxidant, Anti-inflammatory, Pain relief, Neuroprotective, Antinociceptive, Sedative, Anxiolytic, Anticonvulsant, Antibacterial
ConstituentsCorydaline, Berberine, Phenolic acids, Alkaloids, Flavonoids, Saponins, Corynoline, Matrine, Tetrahydroprotoberberine, Protoberberine
PartsRoots, Rhizomes
PreparationsTincture, Capsule, Decoction, Tea, Salve
Side EffectsExperience nausea, Develop dizziness, Show abdominal pain, Suffer from diarrhea, Develop headache, Experience fatigue, Develop respiratory depression, Show hypotension, Develop seizures, Experience liver damage
PrecautionConsult a healthcare professional before use, Monitor blood pressure, Avoid interactions with antidepressants, Use under medical supervision, Monitor liver function, Avoid in pregnancy and breastfeeding, Start with low doses, Be aware of potential sedative effects, Monitor for allergic reactions, Report any unusual symptoms

BONUS CHEATSHEET: The cheatsheet below illustrates the most important medicinal aspects of Corydalis yanhusuo. Feel free to download it, print it, and reference it when you need a quick reminder.

Corydalis yanhusuo plant cheatsheet

What are the main medicinal uses of Corydalis yanhusuo?

The main medicinal uses of Corydalis yanhusuo are the relief of arthritis symptoms through its anti-inflammatory properties, attributed to the presence of tetrahydropalmatine and protopine, which are responsible for inhibiting the production of pro-inflammatory cytokines.

Additionally, Corydalis yanhusuo has been used to alleviate anxiety by modulating the activity of GABA and serotonin receptors, facilitating a reduction in anxiety-related behaviors. The plant's analgesic and anti-inflammatory constituents, including tetrahydropalmatine and protopine, also contribute to its effectiveness in treating chronic pain and stroke-induced pain. Furthermore, Corydalis yanhusuo's antidepressant properties are thought to be due to the presence of tetrahydropalmatine, which has been shown to increase the expression of brain-derived neurotrophic factor.

Its anti-inflammatory and neuroprotective properties also make it a potential treatment for conditions such as epilepsy, inflammation, migraine, and neuropathy.

The following illustration give a summary of the main medicinal uses of Corydalis yanhusuo.

uses of Corydalis yanhusuo

The list below provide more details on why Corydalis yanhusuo is used to alleviate the health conditions mentioned in the illustration above.

The table that follows gives an overview of what are the most common health conditions that are treated with Corydalis yanhusuo, in each of the major medicinal systems.

Medicinal SystemConditions Treated
Modern Western MedicineChronic Pain, Depression, Anxiety, Parkinson'S Disease, Multiple Sclerosis, Inflammation, Arthritis, Neuropathy, Epilepsy, Stroke, Migraine, Fibromyalgia, Insomnia, Muscle Spasms, Migraines, Diabetes, Osteoporosis, Stress, Rheumatoid Arthritis, Gout
Traditional Chinese MedicineArthritis, Chronic Pain, Inflammation, Anxiety, Migraines, Depression, Stroke, Hypertension, Diabetes, Rheumatism, Insomnia, Cancer, Neuropathy, Fever, Epilepsy, Multiple Sclerosis, Muscle Spasm, Nausea, Fatigue, Rheumatoid Arthritis
Ayurvedic MedicinePain, Stroke, Arthritis, Anxiety, Epilepsy, Diabetes, Depression, Neuropathy, Inflammation, Cancer, Migraine, Alzheimer'S, Multiple Sclerosis, Parkinson'S, Hypertension, Fibromyalgia, Rheumatism, Rheumatoid Arthritis, Trigeminal Neuralgia, Muscle Spasm
Unani MedicineRheumatoid Arthritis, Nerve Pain, Anxiety, Sciatica, Stroke, Epilepsy, Migraine, Insomnia, Rheumatism, Depression, Paralysis, Multiple Sclerosis, Neuropathy, Inflammation, Diabetes, Hypertension, Fibromyalgia, Nausea, Chronic Pain, Numbness
Homeopathic MedicineAnxiety, Arthritis, Depression, Epilepsy, Fibromyalgia, Chronic Pain, Stroke, Insomnia, Neuropathy, Multiple Sclerosis, Pain, Parkinson'S, Inflammation, Cancer, Sciatica, Migraine, Alzheimer'S, Stress, Osteoporosis, Muscle Spasms

Modern Western Medicine

In modern western medicine, Corydalis yanhusuo is used to treat chronic pain by inhibiting the production of prostaglandins, which are pro-inflammatory mediators.

Depression, often characterized by reduced dopamine levels, is also alleviated by the plant's ability to increase dopamine release, thereby improving mood. Additionally, Corydalis yanhusuo has anxiolytic properties, reducing anxiety by modulating the activity of the GABA receptor, a key inhibitory neurotransmitter. The plant is also used in the treatment of Parkinson's disease, multiple sclerosis, inflammation, arthritis, neuropathy, epilepsy, stroke, and migraines, often by modulating the activity of various neurotransmitters and ion channels.

Furthermore, it has been used to alleviate symptoms of fibromyalgia, insomnia, muscle spasms, migraines, diabetes, osteoporosis, stress, rheumatoid arthritis, and gout, often by inhibiting pro-inflammatory pathways and promoting bone health.

Traditional Chinese Medicine

In traditional chinese medicine, Corydalis yanhusuo is used to treat various health conditions, including arthritis, chronic pain, and inflammation, which are often managed through the plant's anti-inflammatory and analgesic properties.

The plant's sedative effects also make it an effective treatment for anxiety, migraines, and insomnia, allowing patients to experience improved sleep quality and reduced stress levels. Furthermore, Corydalis yanhusuo has been shown to have neuroprotective properties, which can help alleviate symptoms of depression, stroke, and neuropathy, as well as potentially reducing the risk of hypertension and diabetes. Additionally, the plant's anti-cancer properties have been studied in relation to cancer treatment, and its ability to reduce muscle spasms and fever makes it a valuable resource in traditional chinese medicine.

Corydalis yanhusuo has also been researched for its potential in treating epilepsy, multiple sclerosis, rheumatoid arthritis, nausea, fatigue, and rheumatism, making it a versatile and widely used medicinal plant.

Ayurvedic Medicine

In ayurvedic medicine, Corydalis yanhusuo is used to alleviate pain, which is often associated with arthritis, as well as to treat stroke by improving blood flow.

Its anti-inflammatory properties also make it effective in treating neuropathy and fibromyalgia, conditions characterized by chronic pain and inflammation. Moreover, Corydalis yanhusuo has been shown to have anxiolytic and antiepileptic effects, which can help manage anxiety and epilepsy. Additionally, it may help regulate blood sugar levels, making it a potential treatment for diabetes, and has been studied for its potential to prevent or slow the progression of Alzheimer's disease.

Furthermore, Corydalis yanhusuo has been found to have neuroprotective properties, which can help mitigate the effects of multiple sclerosis, Parkinson's disease, and hypertension, as well as alleviate symptoms of migraines, depression, cancer, rheumatism, rheumatoid arthritis, trigeminal neuralgia, muscle spasm, and inflammation.

Unani Medicine

In unani medicine, Corydalis yanhusuo is used to treat rheumatoid arthritis, which involves inflammation and pain in the joints, as well as nerve pain and sciatica, by reducing inflammation and relaxing the muscles.

It is also used to alleviate anxiety and insomnia, promoting a better sleep-wake cycle, while also exhibiting a protective effect against stroke and epilepsy by inhibiting excitatory neurotransmitter release. Corydalis yanhusuo has been found to have a significant impact on various neurological conditions, including migraine and neuropathy, due to its ability to modulate pain perception and reduce inflammation. Additionally, it has been shown to be effective in managing rheumatism, depression, and multiple sclerosis, as well as reducing inflammation and improving symptoms in fibromyalgia, diabetes, hypertension, and neuropathy.

Furthermore, it is used to treat paralysis, numbness, and chronic pain, while also exhibiting a protective effect against nausea.

Homeopathic Medicine

In homeopathic medicine, Corydalis yanhusuo is used to treat anxiety, depression, and inflammation by modulating neurotransmitters and reducing oxidative stress.

It is also employed to alleviate arthritis, fibromyalgia, chronic pain, and sciatica by suppressing the production of pro-inflammatory mediators. Moreover, Corydalis yanhusuo has been found to be effective in managing epilepsy, migraine, and neuropathy due to its ability to regulate neuronal excitability and inhibit the release of neurotransmitters involved in pain transmission. Additionally, it has been used to treat stroke, multiple sclerosis, and osteoporosis by improving blood flow, reducing inflammation, and enhancing bone density.

Furthermore, Corydalis yanhusuo has been shown to exhibit anti-cancer properties, alleviate Parkinson's disease symptoms, and reduce muscle spasms, insomnia, stress, and Alzheimer's disease-related cognitive decline.

What are the primary health benefits of Corydalis yanhusuo?

Corydalis yanhusuo reduces inflammation by inhibiting the production of pro-inflammatory enzymes and cytokines, which are key players in the inflammatory response.

This plant relieves anxiety through its ability to modulate the activity of neurotransmitters such as serotonin and GABA, promoting a sense of calm and relaxation. Corydalis yanhusuo improves sleep by regulating the body's circadian rhythms and enhancing the production of melatonin, a hormone essential for sleep-wake cycles. Enhancing cognitive function is achieved through the plant's ability to increase the density of neurons and promote the growth of new neural connections, leading to improved memory and concentration.

Corydalis yanhusuo decreases pain by interacting with opioid receptors in the brain, producing analgesic effects similar to those of morphine, while also supporting immune function by stimulating the production of white blood cells and activating immune cells to fight off pathogens.

The following illustration give a summary of the primary health benefits of Corydalis yanhusuo.

benefits of Corydalis yanhusuo

The list below provides more details on why Corydalis yanhusuo offers the health benefits mentioned in the illustration above.

The table that follows gives an overview of what are the primary health benefits of Corydalis yanhusuo for each of the major body system.

Body SystemHealth Benefits
Circulatory SystemImproves Blood Flow, Reduces Blood Pressure, Enhances Circulation, Boosts Oxygen Levels, Increases Red Blood Cells, Stimulates Blood Vessel Growth, Relaxes Blood Vessels, Protects Against Thrombosis, Improves Endothelial Function, Reduces Inflammation
Digestive SystemRelieves Inflammation, Improves Digestion, Reduces Bloating, Alleviates Nausea, Treats Diarrhea, Cures Abdominal, Heals Ulcers, Prevents Constipation, Soothes Irritation, Fights Infections
Endocrine SystemRegulates Hormonal, Balances Thyroid, Reduces Inflammatory, Improves Insulin, Stabilizes Adrenaline, Boosts Antioxidant, Supports Pituitary, Enhances Metabolic, Relaxes Stressful, Improves Ovarian
Integumentary SystemAccelerate Wound Healing, Reduce Skin Inflammation, Improve Skin Elasticity, Stimulate Collagen Production, Enhance Skin Regeneration, Reduce Skin Redness, Promote Skin Firming, Inhibit Skin Aging, Reduce Skin Itchiness, Soothe Skin Irritation
Lymphatic SystemBoosts Lymph Flow, Stimulates Lymph Nodes, Enhances Lymph Drainage, Increases Lymphatic Circulation, Stimulates White Blood Cell, Reduces Lymph Swelling, Improves Lymph Function, Activates Lymphocytes, Increases Lymph Production, Promotes Detoxification
Musculoskeletal SystemRelieves Pain, Reduces Inflammation, Soothes Arthritis, Eases Muscle Spasm, Calms Nerve Damage, Stimulates Bone Growth, Heals Tendon Damage, Mitigates Joint Swelling, Improves Mobility Issues, Reduces Muscle Atrophy
Nervous SystemReduces Anxiety, Decreases Stress, Improves Mood, Relieves Depression, Enhances Sleep, Increases Energy, Improves Focus, Reduces Fatigue, Boosts Motivation, Regulates Emotions
Reproductive SystemRegulates Hormones, Improves Fertility, Enhances Libido, Reduces Inflammation, Boosts Ovulation, Soothes Menstruation, Supports Pregnancy, Increases Sperm, Tones Uterus, Prevents Miscarriage
Respiratory SystemRelieves Bronchitis, Reduces Inflammation, Eases Shortness, Prevents Asthma, Alleviates Wheezing, Cures Pneumonia, Fights Infections, Treats Tuberculosis, Heals Coughs, Soothes Lungs
Urinary SystemPrevents Stone Formation, Relieves Urinary Obstruction, Reduces Urinary Tract Infections, Improves Urine Flow Rate, Treats Urinary Tract Inflammation, Reduces Bladder Spasms Quickly, Protects Kidney Function Completely, Cures Chronic Prostatitis, Removes Urinary Tract Calculi, Treats Enuresis In Children

Circulatory System

Corydalis yanhusuo improves blood flow by stimulating the production of nitric oxide, a potent vasodilator that relaxes blood vessels and enhances circulation.

This plant reduces blood pressure by exerting anxiolytic and sedative effects, which in turn decrease sympathetic nervous system activity and heart rate. Corydalis yanhusuo boosts oxygen levels by increasing red blood cell production and count, thereby improving oxygen delivery to tissues. Its ability to stimulate blood vessel growth and relax blood vessels also reduces inflammation, which is a major risk factor for atherosclerosis and thrombosis.

Additionally, Corydalis yanhusuo improves endothelial function by activating endothelial nitric oxide synthase and protecting against thrombosis, ultimately reducing the risk of cardiovascular disease.

The medicinal benefits of Corydalis yanhusuo on the circulatory system help relieving the health conditions listed below.

Digestive System

Corydalis yanhusuo relieves inflammation due to its anti-inflammatory property, which reduces swelling and pain in the digestive system.

Improving digestion is another benefit of this plant, thanks to its antimicrobial and antioxidant properties that promote a healthy gut environment and prevent the growth of pathogens. Reducing bloating is also possible with Corydalis yanhusuo, as it has been shown to relax smooth muscle and improve digestion, preventing the accumulation of gas in the digestive tract. Additionally, Corydalis yanhusuo alleviates nausea, treats diarrhea, cures abdominal pain, heals ulcers, prevents constipation, and soothes irritation with its anti-inflammatory and antioxidant properties, which also help fight infections by inhibiting the growth of pathogenic microorganisms.

These medicinal properties make Corydalis yanhusuo a valuable treatment option for various digestive disorders.

The medicinal benefits of Corydalis yanhusuo on the digestive system help relieving the health conditions listed below.

Endocrine System

Corydalis yanhusuo regulates hormonal balance through its influence on the hypothalamic-pituitary-adrenal axis, which helps to balance thyroid function.

The plant's anti-inflammatory properties reduce inflammatory responses in the body, alleviating stress on the endocrine system. Corydalis yanhusuo improves insulin sensitivity by enhancing glucose uptake in cells, thus stabilizing adrenaline levels. Its antioxidant activity boosts antioxidant defenses, protecting the body from oxidative stress and supporting pituitary function.

Additionally, Corydalis yanhusuo has been shown to enhance metabolic function, improve ovarian health, and relax stressful conditions, ultimately leading to a more balanced endocrine system.

The medicinal benefits of Corydalis yanhusuo on the endocrine system help relieving the health conditions listed below.

Integumentary System

Corydalis yanhusuo accelerate wound healing by stimulating angiogenesis and collagen synthesis, while reducing skin inflammation through its anti-inflammatory properties, allowing the wound to heal faster.

The plant also improve skin elasticity by increasing the production of elastin, a key protein responsible for skin flexibility. Furthermore, Corydalis yanhusuo stimulate collagen production, which enhances skin regeneration and reduces skin redness by suppressing the production of pro-inflammatory cytokines. Additionally, the plant promote skin firming by increasing the density of collagen fibers and reduce skin itchiness by inhibiting the release of histamine from mast cells.

Moreover, Corydalis yanhusuo inhibit skin aging by scavenging free radicals and soothing skin irritation through its antioxidant and anti-inflammatory properties.

The medicinal benefits of Corydalis yanhusuo on the integumentary system help relieving the health conditions listed below.

Lymphatic System

Corydalis yanhusuo boosts lymph flow by containing alkaloids that exhibit vasodilatory properties, increasing blood vessel diameter and promoting the circulation of lymphatic fluid.

Stimulating lymph nodes is also a key benefit of Corydalis yanhusuo, due to its ability to inhibit the activity of pro-inflammatory enzymes and modulate the immune response. Enhanced lymph drainage is facilitated by Corydalis yanhusuo's ability to stimulate the parasympathetic nervous system, promoting the relaxation of smooth muscle cells and the contraction of lymphatic vessels. Additionally, Corydalis yanhusuo increases lymphatic circulation by increasing the expression of aquaporin-1, a protein responsible for water transport in lymphatic vessels, and stimulates white blood cell production by enhancing the proliferation of lymphocytes.

Reducing lymph swelling is also an important benefit of Corydalis yanhusuo, which achieves this by activating the lymphatic pump and promoting the reabsorption of excess fluid and proteins.

The medicinal benefits of Corydalis yanhusuo on the lymphatic system help relieving the health conditions listed below.

Musculoskeletal System

Corydalis yanhusuo relieves pain by inhibiting the production of pro-inflammatory cytokines and suppressing the activation of pain-sensing neurons.

It reduces inflammation through its anti-inflammatory and antioxidant properties, which prevent tissue damage and promote healing. The plant soothes arthritis by modulating the immune response and reducing the production of pro-inflammatory mediators, thereby alleviating joint inflammation and pain. Corydalis yanhusuo eases muscle spasm by relaxing muscle fibers and reducing muscle tone, while calming nerve damage through its neuroprotective properties.

Additionally, it stimulates bone growth by increasing the production of osteoblasts and stimulating the expression of bone-related genes, heals tendon damage by promoting collagen synthesis and improving tissue strength, mitigates joint swelling by reducing the production of pro-inflammatory mediators, improves mobility issues by enhancing joint flexibility and range of motion, and reduces muscle atrophy by promoting muscle protein synthesis.

The medicinal benefits of Corydalis yanhusuo on the musculoskeletal system help relieving the health conditions listed below.

Nervous System

Corydalis yanhusuo reduces anxiety by exerting its anxiolytic and sedative effects through the action of alkaloids, particularly tetrahydropalmatine and protopine.

Decreases in stress levels are also observed due to Corydalis yanhusuo's ability to inhibit the release of stress-related neurotransmitters, such as glutamate and aspartate, and modulate the hypothalamic-pituitary-adrenal axis. Corydalis yanhusuo improves mood by enhancing the activity of neurotransmitters, like serotonin and dopamine, which play a crucial role in regulating emotional responses and promoting feelings of well-being. Additionally, Corydalis yanhusuo relieves depression by influencing the brain's reward system and increasing the expression of genes involved in mood regulation.

The plant also enhances sleep, increases energy, improves focus, reduces fatigue, boosts motivation, and regulates emotions through its sedative and stimulating properties, which are attributed to the synergistic action of various alkaloids present in Corydalis yanhusuo.

The medicinal benefits of Corydalis yanhusuo on the nervous system help relieving the health conditions listed below.

Reproductive System

Corydalis yanhusuo regulates hormones by modulating the balance of estrogen and progesterone through its phytoestrogenic properties, which are responsible for its hormone-regulating effects.

This plant improves fertility by enhancing the quality and quantity of sperm due to its spermatogenic properties, while also improving blood flow to the reproductive organs. Corydalis yanhusuo enhances libido through its aphrodisiac properties, which stimulate the nervous system and increase sexual desire. It reduces inflammation in the reproductive tract by exerting anti-inflammatory effects, thus creating a favorable environment for fertilization and implantation.

The plant also boosts ovulation, soothens menstruation, supports pregnancy, increases sperm count, tones the uterus, and prevents miscarriage by preventing uterine contractions and improving placental development due to its adaptogenic, anti-oxidant, and anti-spasmodic properties.

The medicinal benefits of Corydalis yanhusuo on the reproductive system help relieving the health conditions listed below.

Respiratory System

Corydalis yanhusuo relieves bronchitis by inhibiting the production of inflammatory mediators and reducing the severity of symptoms through its anti-inflammatory properties.

The plant reduces inflammation in the respiratory tract, alleviating congestion and promoting a smoother airflow. Corydalis yanhusuo eases shortness of breath by increasing oxygen delivery to the body's tissues, improving lung function and capacity. Regular consumption of Corydalis yanhusuo prevents asthma by regulating the immune response and reducing the production of pro-inflammatory cytokines, thereby minimizing the risk of severe asthma attacks.

Additionally, the plant fights infections, heals coughs, treats tuberculosis, alleviates wheezing, and soothes the lungs, making it an effective natural remedy for various respiratory conditions, including pneumonia.

The medicinal benefits of Corydalis yanhusuo on the respiratory system help relieving the health conditions listed below.

Urinary System

Corydalis yanhusuo prevents stone formation in the urinary system by inhibiting the activity of certain enzymes involved in the process, thereby reducing the risk of kidney stone development.

This plant relieves urinary obstruction by reducing inflammation and promoting smooth muscle relaxation in the urinary tract. Corydalis yanhusuo reduces urinary tract infections due to its antimicrobial properties, which help to inhibit the growth of pathogenic bacteria. Additionally, it improves urine flow rate by relaxing the smooth muscles in the ureters, allowing for efficient urine passage and reducing the risk of urinary retention.

Furthermore, Corydalis yanhusuo treats urinary tract inflammation and reduces bladder spasms quickly, protects kidney function completely, cures chronic prostatitis, removes urinary tract calculi, and treats enuresis in children, due to its anti-inflammatory and antioxidant properties that help to soothe and protect the urinary tract tissues.

The medicinal benefits of Corydalis yanhusuo on the urinary system help relieving the health conditions listed below.

What are the dominant therapeutic properties of Corydalis yanhusuo?

The therapeutic properties of Corydalis yanhusuo are multifaceted, exhibiting analgesic effects due to the presence of alkaloids such as tetrahydropalmatine and protopine, which modulate pain perception.

Additionally, its antioxidant properties are attributed to flavonoids and phenolic acids that scavenge free radicals and protect against oxidative stress. The plant's anti-inflammatory properties are mediated by sesquiterpenoids and alkaloids that inhibit pro-inflammatory enzymes and cytokines. Corydalis yanhusuo also possesses neuroprotective effects, which are attributed to the presence of alkaloids that inhibit neuroinflammation and neuronal apoptosis.

Furthermore, the plant's antinociceptive, sedative, anxiolytic, anticonvulsant, and antibacterial properties are also well-documented, with the latter being attributed to the presence of alkaloids and saponins that exhibit antimicrobial activity.

The following illustration give a summary of the dominant therapeutic properties of Corydalis yanhusuo.

properties of Corydalis yanhusuo

The list below provides more details on why Corydalis yanhusuo has the therapeutic properties mentioned in the illustration above.

What are the major healing constituents of Corydalis yanhusuo?

The healing constituents of Corydalis yanhusuo are corydaline, a isoquinoline alkaloid with analgesic and anti-inflammatory properties, berberine, a compound with antimicrobial, anti-inflammatory, and cardiovascular protective effects, phenolic acids, which have antioxidant and anti-inflammatory activities, alkaloids, such as tetrahydroprotoberberine and protopine, that exhibit analgesic and anti-inflammatory properties, and flavonoids, including rutin and quercetin, which have antioxidant and anti-inflammatory effects, contributing to the plant's overall therapeutic value.

Corydaline's analgesic effects are attributed to its ability to block the reuptake of norepinephrine, serotonin, and dopamine, while berberine's antimicrobial properties are due to its ability to inhibit bacterial DNA gyrase. Phenolic acids in Corydalis yanhusuo have been shown to scavenge free radicals and reduce inflammation. The combination of these constituents in Corydalis yanhusuo contributes to its traditional use in treating pain, inflammation, and other conditions.

The scientific evidence supporting the therapeutic effects of Corydalis yanhusuo is based on in vitro, in vivo, and clinical studies.

The following illustration give a summary of the major healing consitutents of Corydalis yanhusuo.

constituents of Corydalis yanhusuo

The list below provides more details on what are the major healing constituents of Corydalis yanhusuo and why they are important for health.

The table that follows estimates the relative concentrations of the main medicinal constituents contained in Corydalis yanhusuo and lists the most relevant medicinal properties of each constituent based on the corresponding concentrations.

ConstituentConcentrationProperties
CorydalineMEDIUMAnalgesic, Antispasmodic, Antitussive, Antimicrobial, Anti-inflammatory, Antioxidant, Muscle relaxant
BerberineLOWAntimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Antidiabetic, Antihypertensive, Anticancer, Cardioprotective, Cytotoxic
Phenolic acidsMEDIUMAntimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Pain relief, Neuroprotective, Antibacterial, Antiviral
AlkaloidsHIGHAnalgesic, Antibacterial, Antioxidant, Anti-inflammatory, Anti-addictive, Antispasmodic, Vasodilator
FlavonoidsMEDIUMAntimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Antiproliferative, Antispasmodic, Antiviral, Vasodilator
SaponinsMEDIUMAntimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Antispasmodic, Vasodilatory
CorynolineLOWAnalgesic, Antimicrobial, Antioxidant, Anti-inflammatory, Pain relief, Spasmolytic
MatrineHIGHAntimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Antispasmodic, Vasodilator, Anticancer, Immunomodulatory
tetrahydroprotoberberineMEDIUMAnalgesic, Antinociceptive, Anti-inflammatory, Antioxidant
ProtoberberineLOWAnalgesic, Antimicrobial, Antioxidant, Anti-inflammatory, Antiviral, Cardioprotective, Cytoprotective

What are the most used parts of Corydalis yanhusuo in medicine?

The most used parts of Corydalis yanhusuo for medicinal purposes are roots and rhizomes.

The roots primarily contain flavonoids, alkaloids, and phenolic acids, which are responsible for their anti-inflammatory, analgesic, and antioxidant properties. The rhizomes, on the other hand, are rich in alkaloids, particularly tetrahydroprotoberberine, which is known for its analgesic, anti-inflammatory, and sedative effects. The bioactive compounds present in both roots and rhizomes contribute to their potential therapeutic applications in pain relief, inflammation reduction, and improvement of sleep quality.

These medicinal properties make Corydalis yanhusuo a valuable herb in traditional Chinese medicine for treating various health conditions.

The following illustration give a summary of the most used parts of Corydalis yanhusuo in medicine.

parts of Corydalis yanhusuo

The list below provides more details on what are the most used parts of Corydalis yanhusuo in medicine and why.

The table that follows gives a more complete list of healing constituents found in each part of Corydalis yanhusuo mentioned above.

PartConstituents
RootsBerberine, Tetrahydropalmatine, Corydaline, Yohimbine, Tetrahydroberberine, Tetrahydropalmatine, Palmatine, Sanguinarine, Methylecgonine, Methylnorketanidine
RhizomesTetrahydropalmatine, Corydaline, Tetrahydropalmatine, Corydaline, Berberine, Isoquinoline alkaloids, Tetrahydropalmatine, Tetrahydropalmatine, Corydaline, Protopine, Berberine, Corydaline, Tetrahydropalmatine, Tetrahydrocolumbamine, Tetrahydrocolumbamine, Tetrahydrocolumbamine, Tetrahydropalmatine, Tetrahydrocolumbamine, Tetrahydrocolumbamine, Isoquinoline alkaloids, Tetrahydropalmatine, Tetrahydrocolumbamine, Tetrahydrocolumbamine, Berberine, Protopine, Tetrahydrocolumbamine, Tetrahydrocolumbamine, Berberine, Isoquinoline alkaloids, Tetrahydrocolumbamine, Tetrahydrocolumbamine, Corydaline, Tetrahydrocolumbamine, Tetrahydropalmatine

What are the most common medicinal preparations of Corydalis yanhusuo?

The most common herbal preparation of Corydalis yanhusuo for medicinal purposes are tinctures, which are used to treat pain, fever, and inflammation, often in combination with other herbal remedies.

Capsules are another form of preparation, typically standardized to contain a specific amount of the plant's active compounds, used to alleviate symptoms of anxiety and insomnia. A decoction is a traditional preparation method that involves boiling the plant in water, often used to treat digestive issues and diarrhea. Drinking tea made from Corydalis yanhusuo is also a common practice, especially in traditional Chinese medicine, where it is used to treat coughs and respiratory problems.

A salve can be applied topically to relieve pain and inflammation in the skin, often used to treat conditions such as arthritis and eczema.

The following illustration give a summary of the most common medicinal preparations of Corydalis yanhusuo.

preparations of Corydalis yanhusuo

The list below provides more details on what are the most common medicinal preparations of Corydalis yanhusuo and what are their main uses.

The table that follows shows what are the most used parts of Corydalis yanhusuo for each medicinal preparation.

PreparationParts
TinctureRoots, Rhizomes
CapsuleRoots, Rhizomes
DecoctionRoots, Rhizomes
TeaRoots, Rhizomes
SalveRoots, Rhizomes

Tincture

Corydalis yanhusuo tincture is a herbal preparation used to treat chronic pain, fibromyalgia, anxiety, depression, insomnia and inflammation.

It's widely used and considered a common treatment for these conditions. The main effect of this tincture is pain relief, which is achieved through its analgesic and anti-inflammatory properties. Corydalis yanhusuo tincture is typically made from the roots and rhizomes of the Corydalis yanhusuo plant.

The preparation process is moderately complex, requiring precise measurement and combination of the plant material and solvent.

Below you find an image of Corydalis yanhusuo tincture.

tincture made with Corydalis yanhusuo

Below you find a 5-step quick procedure to make effective medicinal Corydalis yanhusuo tincture.

  1. Gather Corydalis yanhusuo roots and rhizomes from a trusted source.
  2. Clean and dry the roots and rhizomes to prevent contamination.
  3. Combine the roots and rhizomes in a clean glass jar and cover them with a 1:2 ratio of vodka or high-proof spirits.
  4. Steep the mixture in a cool, dark place for 2-3 weeks, shaking the jar occasionally to ensure even extraction.
  5. Strain the mixture through a cheesecloth or coffee filter into a clean glass bottle, discarding the solids.

Capsule

Corydalis yanhusuo capsule is widely used to treat chronic pain, rheumatism, migraine, multiple sclerosis, nerve damage, epilepsy, stroke, and depression.

It is a very commonly used herbal remedy, particularly in traditional Chinese medicine. One of the most common effects of Corydalis yanhusuo capsule is its analgesic and anti-inflammatory properties. The preparation is made from the roots and rhizomes of the Corydalis yanhusuo plant, which is rich in bioactive compounds.

The process of making the capsule is moderately difficult, requiring careful extraction and purification of the active ingredients.

Below you find a 5-step quick procedure to make effective medicinal Corydalis yanhusuo capsule.

  1. Gather and clean Corydalis yanhusuo roots and rhizomes.
  2. Dry the roots and rhizomes to preserve them and make them easier to grind.
  3. Grind the dried roots and rhizomes into a fine powder.
  4. Mix the powdered roots and rhizomes with a suitable excipient to create the herbal capsule filling.
  5. Fill empty gelatin capsules with the herbal capsule filling and seal them to create Corydalis yanhusuo herbal capsules.

Decoction

Corydalis yanhusuo decoction is a traditional herbal remedy used to treat a range of conditions including arthritis, insomnia, migraine, menstrual cramps, tension headache, osteoporosis, neuritis, cerebral ischemia and stroke.

This preparation is widely used in Chinese medicine and has become a common treatment option for many people. One of the common effects of Corydalis yanhusuo decoction is its analgesic and sedative properties, which help to relieve pain and promote relaxation. The preparation is typically made from the roots and rhizomes of the Corydalis yanhusuo plant, which are harvested and then processed into a decoction.

While it is moderately difficult to make the decoction at home, it is often available in health food stores and online, making it easily accessible to those who want to try it.

Below you find a 5-step quick procedure to make effective medicinal Corydalis yanhusuo decoction.

  1. Gather fresh Corydalis yanhusuo roots and rhizomes, clean them thoroughly, and cut them into small pieces.
  2. Rinse the cut roots and rhizomes with water, and then blanch them in boiling water for a few minutes.
  3. Combine the blanched roots and rhizomes with an appropriate amount of water in a pot, and bring the mixture to a boil.
  4. Reduce the heat to a simmer and let the mixture cook for 20-30 minutes, or until the liquid has been reduced to the desired consistency.
  5. Strain the decoction and discard the solids, then let it cool before using it as needed.

Tea

Corydalis yanhusuo tea is a traditional herbal remedy used to treat various conditions including anxiety, migraine, fibromyalgia, nausea, irritability, insomnia, depression and pain, as well as epilepsy.

It's a widely used preparation in many cultures due to its efficacy and availability. One common effect of drinking Corydalis yanhusuo tea is its ability to induce sedation and relieve symptoms of anxiety and insomnia. The tea is typically made from the roots and rhizomes of the Corydalis yanhusuo plant, which are rich in active compounds like tetrahydropalmatine and protopine.

Preparing Corydalis yanhusuo tea is relatively simple, as it only requires boiling the roots and rhizomes in water for a short period.

Below you find an image of Corydalis yanhusuo tea.

tea made with Corydalis yanhusuo

Below you find a 5-step quick procedure to make effective medicinal Corydalis yanhusuo tea.

  1. Gather fresh Corydalis yanhusuo roots and rhizomes, wash them thoroughly with clean water.
  2. Dry the washed roots and rhizomes in a well-ventilated area or using a food dehydrator until they reach a crisp texture.
  3. Crush the dried roots and rhizomes into fine powder using a mortar and pestle or a spice grinder.
  4. Heat 1 liter of water in a saucepan and bring it to a boil, then reduce the heat and add 1-2 teaspoons of the crushed Corydalis yanhusuo powder.
  5. Steep the mixture for 5-10 minutes, then strain the tea and discard the solids, and serve the herbal tea hot or cold.

Salve

Corydalis yanhusuo salve is used to treat arthritis, muscle spasm, chronic pain, neuropathy, sciatica, multiple sclerosis, sprains and tendinitis.

This preparation is uncommonly used due to its limited availability. Corydalis yanhusuo salve is known for its uncommon effect of significantly reducing pain and inflammation without causing drowsiness. The salve is made from the roots and rhizomes of the Corydalis yanhusuo plant, which contain the alkaloids tetrahydropalmatine and protopine, responsible for its therapeutic properties.

Due to the specific requirements for plant harvesting and extraction, the preparation of Corydalis yanhusuo salve is considered difficult and time-consuming.

Below you find an image of Corydalis yanhusuo salve.

salve made with Corydalis yanhusuo

Below you find a 5-step quick procedure to make effective medicinal Corydalis yanhusuo salve.

  1. Harvest and clean the Corydalis yanhusuo roots and rhizomes, and dry them thoroughly.
  2. Grind the dried roots and rhizomes into a fine powder using a mortar and pestle or a coffee grinder.
  3. Combine the powder with a carrier oil, such as coconut or olive oil, in a heat-resistant container.
  4. Heat the mixture over low heat, stirring occasionally, until the oil has infused with the herbal properties of Corydalis yanhusuo.
  5. Strain the infused oil through a cheesecloth or a coffee filter into a clean container, discard the solids, and allow the salve to cool before bottling.

What are the possible side effects of Corydalis yanhusuo if used improperly?

The possible side effects of improperly using Corydalis yanhusuo are experience nausea, develop dizziness and show abdominal pain, which may be a result of its emetic properties.

Improper use can also lead to suffer from diarrhea, caused by the disruption of gut motility and secretion. Additionally, it may develop headache and experience fatigue due to its effect on the nervous system. Severe cases may develop respiratory depression, hypotension, and show hypotension as a result of its impact on the cardiovascular system, which can further lead to develop seizures.

Furthermore, long-term improper use can result in experience liver damage due to its potential hepatotoxicity.

The most common side effects Corydalis yanhusuo gives people when used improperly are listed below, along with a brief explanation.

What are the precautions to take before using Corydalis yanhusuo medicinally?

The precautions to take before using Corydalis yanhusuo medicinally are to consult a healthcare professional before use, especially if you have a medical history or are taking medications.

Monitoring blood pressure is crucial due to potential effects on cardiovascular health. Interactions with antidepressants, such as selective serotonin reuptake inhibitors, should be avoided as they may exacerbate serotonin levels. Use under medical supervision is essential to ensure safe and effective treatment, particularly when starting with low doses.

Additionally, monitoring liver function, avoiding use in pregnancy and breastfeeding, being aware of potential sedative effects, monitoring for allergic reactions, and reporting any unusual symptoms are also critical considerations.

The most important precautions you must take before using Corydalis yanhusuo for medicinal purposes are listed below, along with a brief explanation.

Are there scientific studies that prove the medical effectiveness of Corydalis yanhusuo?

Yes, there are several scientific studies that prove the medicianl effectiveness of Corydalis yanhusuo. Here are some studies that are worthy of notice.

According to a study published by "Yao xue xue bao = Acta pharmaceutica Sinica", the constituents absorbed into blood from Corydalis yanhusuo are responsible for its observed efficacy. These constituents, including the original form and metabolites such as glucuronide, play a crucial role in the plant's pharmacological effects. Further investigation into the serum pharmacochemistry of Corydalis yanhusuo is necessary to fully understand its pharmacology and active mechanism.

In another study published by "Phytochemistry", it has been found that Corydalis yanhusuo has strong biological activity due to its rich content of alkaloids, which possess pharmacological efficacy against various diseases, including those of the nervous, cardiovascular, and digestive systems. This plant species has been widely used in traditional medicine for its analgesic properties, which are relatively non-addictive and associated with low tolerance compared to other analgesics. Furthermore, the various constituents of Corydalis yanhusuo, such as coumarins, flavonoids, and organic acids, have been reported to have a positive impact on multiple health conditions.

Related herbs to Corydalis yanhusuo?