Asiatic dogwood
Cornus officinalis · Accepted scientific name
Scientific literature: Very Extensive (473 studies) · ★★★★★
Asiatic dogwood, scientifically known as Cornus officinalis, is a versatile medicinal shrub prized in traditional herbalism. Renowned for its restorative properties, its bark and fruit are utilized to support kidney health, nourish the liver, and strengthen the essence. This potent botanical serves as a vital remedy in holistic wellness.
Names and Synonyms
Common Names
- Asiatic dogwood
- Japanese cornel
- Japanese cornelian-cherry
- Korean cornel dogwood
Scientific Names
Accepted name
Cornus officinalisSynonyms
- Cornus mascula var. japonica
- Macrocarpium officinale
- Cornus officinalis var. koreana
Regional and Traditional Names
Spanish:
- Macrocarpium officinale
- Cornus officinalis var. koreana
- Cornus officinalis var koreana
- Cornejo officinalis
German:
- Asiatische Kornelkirsche
- japanische Kornelkirsche
- Asiatische Kornelkirsche
French:
- cornouiller officinal
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta within the class Equisetopsida. It is further categorized under the subclass Magnoliidae and the order Cornales, falling into the family Cornaceae. Finally, its taxonomic identity is defined by the genus Cornus.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Cornales |
| Family | Cornaceae |
| Genus | Cornus |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a broad distribution across various regions of Eastern Asia. In China, its presence is noted in both the North-Central and Southeast territories. Furthermore, the species can be found naturally throughout the Japanese archipelago. It is also widely distributed across the Korean Peninsula. Together, these locations define its primary geographical range within the continent.
| Region | Area |
|---|---|
| China | China North-Central |
| China | China Southeast |
| Eastern Asia | Japan |
| Eastern Asia | Korea |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Life history
The life history of Cornus officinalis is characterized by its perennial nature and its classification under specific life forms, primarily functioning as a phanerophyte. As a phanerophyte, the plant maintains its buds well above the ground level, allowing it to thrive as a woody shrub or small tree in its natural habitats. While it is predominantly categorized as a phanerophyte, its structural growth patterns and environmental adaptations can occasionally align with the characteristics of a nanophanerophyte depending on the specific microhabitat and the height of its woody stems. Throughout its life cycle, the plant undergoes seasonal transitions, developing robust woody structures that support its reproductive processes, eventually producing small, fragrant flowers followed by drupes that ensure the continuation of its lineage through seed dispersal.
- Life form :
- nanophanerophyte
- Life form :
- phanerophyte
Morphology
The morphology of Cornus officinalis is characterized by a woody growth form, specifically manifesting as a perennial shrub or small tree. It is a self-supporting plant that does not exhibit climbing tendencies, such as being a liana or vine, and it functions as an independent organism rather than a parasite. In terms of its ecological habitat and life strategy, it is a terrestrial species, lacking aquatic or semiaquatic adaptations, and it does not function as an epiphyte. Its structure is defined by its permanent woodiness, providing the necessary stability for its upright, self-supporting stature.
- Aquatic :
- terrestrial
- Climber :
- self-supporting
- Epiphyte :
- terrestrial
- Growth form :
- shrub
- Parasite :
- independent
- Woodiness :
- woody
Physiology
The physiology of Cornus officinalis is characterized by a C3 photosynthetic pathway, a metabolic strategy typical of many woody perennial angiosperms that involves the direct fixation of atmospheric carbon dioxide by the enzyme RuBisCO during the Calvin cycle. This C3 mechanism dictates its water-use efficiency and carbon assimilation rates, as the plant relies on maintaining specific stomatal conductance levels to balance gas exchange with transpiration. The physiological processes of the plant are heavily influenced by seasonal temperature fluctuations and photoperiodism, which regulate its vegetative growth and the complex metabolic shifts required for the synthesis of bioactive secondary metabolites. These metabolic pathways are closely integrated with its hydraulic architecture, where the movement of water and nutrients through its xylem supports the energetic demands of both structural maintenance and the biochemical production of its medicinal constituents.
- Photosynthetic pathway :
- C3
Reproduction
The reproduction of Cornus officinalis is characterized by the production of small, drupe-like fruits that contain seeds with highly consistent physical properties. Based on empirical data, the seed mass exhibits no variance across the observed samples, maintaining a precise mean, maximum, and minimum value of 0.13158 g. This uniformity in seed mass suggests a highly stable reproductive strategy, ensuring that each seed carries a standardized amount of nutrient reserves to support initial germination. The dispersal and subsequent growth of the species rely on these consistent seed dimensions, which play a critical role in the plant's ability to establish new individuals within its natural habitat.
- Seed mass mean:
- 0.13158 g
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Cornus officinalis has 2 reported plant parts identified across 11 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include fruit, leaf.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Fruit | 10 supporting sources | ★★★★★ |
| Leaf | 1 supporting sources | ★☆☆☆☆ |
Fruit
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Frontiers in pharmacology
- Chemical & pharmaceutical bulletin
- Molecular medicine reports
- Bioorganic chemistry
View 5 additional sources
- PloS one
- Biomolecules
- Journal of Asian natural products research
- Archives of pharmacal research
- Yakushigaku zasshi
Leaf
- PloS one
Chemicals
Cornus officinalis has 73 reported phytochemicals identified across 11 scientific publications and several other databases. The most consistently reported chemicals include Loganin, Morroniside, Ursolic acid, Cornuside, Flavonoids.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Loganin | 10 supporting sources | ★★★★★ |
| Morroniside | 8 supporting sources | ★★★★☆ |
| Ursolic acid | 4 supporting sources | ★★☆☆☆ |
| Cornuside | 3 supporting sources | ★★☆☆☆ |
| Flavonoids | 3 supporting sources | ★★☆☆☆ |
| Isoterchebin | 3 supporting sources | ★★☆☆☆ |
| OLEANOLIC ACID | 3 supporting sources | ★★☆☆☆ |
| Gallic acid | 2 supporting sources | ★☆☆☆☆ |
| Iridoids | 2 supporting sources | ★☆☆☆☆ |
| Tannins | 2 supporting sources | ★☆☆☆☆ |
Loganin
- Dr. Duke
- Journal of ethnopharmacology
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Journal of pharmaceutical and biomedical analysis
- Molecules (Basel, Switzerland)
View 5 additional sources
- European journal of pharmacology
- Horticulture research
- Phytotherapy research : PTR
- Journal of cosmetic science
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
Morroniside
- Dr. Duke
- Journal of ethnopharmacology
- Journal of pharmaceutical and biomedical analysis
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
View 3 additional sources
- European journal of pharmacology
- Biological & pharmaceutical bulletin
- Frontiers in pharmacology
Ursolic acid
- Dr. Duke
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Molecules (Basel, Switzerland)
- Phytotherapy research : PTR
Cornuside
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Journal of cosmetic science
- Archives of pharmacal research
Flavonoids
- Food research international (Ottawa, Ont.)
- Foods (Basel, Switzerland)
- Journal of ethnopharmacology
Isoterchebin
- Dr. Duke
- Chemical & pharmaceutical bulletin
- Archives of pharmacal research
OLEANOLIC ACID
- Dr. Duke
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Molecules (Basel, Switzerland)
Gallic acid
- Dr. Duke
- Molecules (Basel, Switzerland)
Iridoids
- DNA research : an international journal for rapid publication of reports on genes and genomes
- Journal of ethnopharmacology
Tannins
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Journal of ethnopharmacology
Activities
Cornus officinalis has 272 reported activities identified across 11 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Antidiabetic, Anticancer, Antiinflammatory, Cardioprotective.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Antioxidant | 5 supporting sources | ★★★☆☆ |
| Antidiabetic | 4 supporting sources | ★★☆☆☆ |
| Anticancer | 2 supporting sources | ★☆☆☆☆ |
| Antiinflammatory | 2 supporting sources | ★☆☆☆☆ |
| Cardioprotective | 2 supporting sources | ★☆☆☆☆ |
| Hepatoprotective | 2 supporting sources | ★☆☆☆☆ |
| Hypoglycemic | 2 supporting sources | ★☆☆☆☆ |
| Neuroprotective | 2 supporting sources | ★☆☆☆☆ |
| ACE-Inhibitor | 1 supporting sources | ★☆☆☆☆ |
| Abortifacient | 1 supporting sources | ★☆☆☆☆ |
Antioxidant
- Dr. Duke
- Fitoterapia
- Bioorganic chemistry
- European journal of pharmacology
- Frontiers in pharmacology
Antidiabetic
- Dr. Duke
- Fitoterapia
- Bioorganic chemistry
- European journal of pharmacology
Anticancer
- Dr. Duke
- Fitoterapia
Antiinflammatory
- Dr. Duke
- Phytotherapy research : PTR
Cardioprotective
- Dr. Duke
- Fitoterapia
Hepatoprotective
- Dr. Duke
- Fitoterapia
Hypoglycemic
- Dr. Duke
- Phytotherapy research : PTR
Neuroprotective
- Journal of Asian natural products research
- Phytotherapy research : PTR
ACE-Inhibitor
- Dr. Duke
Abortifacient
- Dr. Duke
Medicinal Uses
Cornus officinalis has 39 reported medicinal uses identified across 11 scientific publications and several other databases. The most consistently reported uses include diabetic nephropathy, inflammation, oxidative stress, Alzheimer's disease, acute lung injury.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| diabetic nephropathy | Journal of pharmaceutical and biomedical analysis (and other 4 sources) | ★★☆☆☆ |
| inflammation | Fitoterapia (and other 4 sources) | ★★☆☆☆ |
| oxidative stress | Archives of pharmacal research (and other 3 sources) | ★★☆☆☆ |
| Alzheimer's disease | Fitoterapia (and other 2 sources) | ★☆☆☆☆ |
| acute lung injury | Journal of ethnopharmacology (and other 2 sources) | ★☆☆☆☆ |
| diabetes mellitus | European journal of pharmacology (and other 2 sources) | ★☆☆☆☆ |
| obesity | Animals : an open access journal from MDPI (and other 2 sources) | ★☆☆☆☆ |
| osteoporosis | Molecules (Basel, Switzerland) (and other 2 sources) | ★☆☆☆☆ |
| spinal cord injury | Fitoterapia (and other 2 sources) | ★☆☆☆☆ |
| weight gain | Animals : an open access journal from MDPI (and other 2 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| aqueous extract | Molecular medicine reports (and other 2 sources) | ★☆☆☆☆ |
| extracts | Archives of pharmacal research (and other 2 sources) | ★☆☆☆☆ |
| fruits | Chemical & pharmaceutical bulletin (and other 2 sources) | ★☆☆☆☆ |
| 50% ethanol extract | Journal of cosmetic science (and other 1 sources) | ★☆☆☆☆ |
| CO ethanol extract | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| Cornus officinalis injection | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (and other 1 sources) | ★☆☆☆☆ |
| HPWS | Journal of pharmaceutical analysis (and other 1 sources) | ★☆☆☆☆ |
| Morroniside | Frontiers in pharmacology (and other 1 sources) | ★☆☆☆☆ |
| Shan-zhu-yu | Yakushigaku zasshi (and other 1 sources) | ★☆☆☆☆ |
| analgesics | DNA research : an international journal for rapid publication of reports on genes and genomes (and other 1 sources) | ★☆☆☆☆ |