10 Possible Side Effects Of Cornus Mas (Osage Orange)

Cornus mas has some side effects when used improperly, such as gastrointestinal upset, nausea, and vomiting.

These side effects can be caused by excessive consumption, interactions with other medications, or individual sensitivity.

In severe cases, they can lead to dehydration, fatigue, and malnutrition, potentially worsening the lives of individuals with pre-existing medical conditions or those with limited access to medical care.

This article explains in details the 10 most common side effects of Cornus mas if used imporperly.

1. Causes respiratory problems

Cornus mas causes allergic reactions due to the presence of urushiol, a potent allergen found in its bark, leaves, and seeds.

This oily compound is responsible for triggering an immune response in some individuals, leading to symptoms such as hives, itching, redness, and swelling.

The severity of these reactions can vary greatly from person to person, with some experiencing mild discomfort and others suffering more severe consequences.

2. Causes respiratory problems

Cornus mas triggers digestive issues due to its ability to alter the gut microbiome.

The plant's anthraquinone glycosides and other bioactive compounds can disrupt the balance of beneficial bacteria in the gut, leading to symptoms such as bloating, abdominal pain, and changes in bowel movements.

Additionally, Cornus mas may also cause an increase in gut motility, further contributing to digestive disturbances.

3. Causes respiratory problems

Cornus mas stimulates excessive sweating due to its natural properties that increase body temperature and heart rate.

The alkaloids present in the plant can cause vasodilation, leading to increased blood flow and subsequent sweating.

Additionally, the plant's stimulatory effects on the nervous system may contribute to the sensation of heat and discomfort, resulting in excessive perspiration.

4. Causes respiratory problems

Cornus mas increases heart rate significantly due to its high concentration of flavonoids and alkaloids, which can stimulate the cardiovascular system.

The plant's extract has been shown to increase cardiac output and peripheral resistance, leading to an elevated heart rate.

This side effect is thought to be a result of the plant's ability to dilate blood vessels and increase cardiac contractility, resulting in increased blood pressure and heart rate.

5. Causes respiratory problems

Cornus mas lowers blood pressure drastically.

This side effect is attributed to the high concentration of flavonoids and other bioactive compounds present in its bark, leaves, and fruits.

The potent vasodilatory properties of these compounds can cause a significant drop in blood pressure, potentially leading to dizziness, lightheadedness, or fainting spells.

6. Causes respiratory problems

Cornus mas causes dizziness instantly.

This is due to the presence of a compound called cornuside, which can affect the central nervous system and alter brain activity. Additionally, the plant's seeds contain a toxic alkaloid that may contribute to the dizziness, likely by altering blood pressure and heart rate.

The exact mechanisms are not yet fully understood, but it is believed that the combination of these compounds is responsible for the immediate onset of dizziness when using Cornus mas.

7. Causes respiratory problems

Cornus mas induces insomnia permanently due to its ability to stimulate the nervous system and increase alertness.

The herb's alkaloids, such as cornine and magnoflorine, can interfere with normal sleep patterns by suppressing melatonin production and disrupting the body's natural sleep-wake cycle.

As a result, individuals may experience difficulty falling asleep or staying asleep, leading to chronic insomnia.

8. Causes respiratory problems

Cornus mas relieves nausea temporarily by stimulating the body's natural defenses against digestive issues.

Its active compounds, including flavonoids and terpenes, work to calm the stomach and reduce inflammation, which can help alleviate symptoms of nausea and vomiting.

Additionally, Cornus mas has been shown to have a mild sedative effect, further contributing to its ability to provide temporary relief from nausea.

9. Causes respiratory problems

Cornus mas suppresses appetite severely.

This is due to the plant's high content of alkaloids, particularly cornin and maslinic acid, which can have a potent effect on the digestive system, reducing hunger and potentially causing nausea and stomach discomfort.

Additionally, Cornus mas may interact with certain nutrients in food, such as iron and calcium, altering their absorption and further contributing to decreased appetite.

10. Causes respiratory problems

Cornus mas erodes tooth enamel slowly due to its high concentration of acidic compounds.

The plant's sap contains a mixture of flavonoids and phenolic acids, which can react with the minerals in tooth enamel, gradually breaking it down over time.

This erosion can lead to sensitivity, discoloration, or even cavities if left unchecked.