10 Medicinal Constituents Of Cornus Mas (Osage Orange)

Cornus mas, also known as Cornelian cherry, has active constituents such as alkaloids (cornine, berberine), flavonoids (rutin, quercetin), and terpenoids.

These constituents possess anti-inflammatory, antioxidant, and antimicrobial properties. The flavonoids in Cornus mas can improve cardiovascular health by reducing blood pressure and cholesterol levels.

Additionally, the antioxidants may protect against age-related diseases, such as Alzheimer's and cancer, by neutralizing free radicals.

This article explains in details the 10 best active constituents of Cornus mas.

1. Berberine

Cornus mas berberine is a bioactive compound extracted from the bark of the European dogwood tree (Cornus mas).

Berberine has been used for centuries in traditional medicine to treat various ailments, including cardiovascular disease, digestive issues, and infections.

It has also been shown to have antimicrobial and antiviral properties, making it a promising natural remedy for a range of health concerns.

2. Rutin

Cornus mas rutin is a type of bioflavonoid found in the bark and leaves of the Dogwood tree (Cornus mas).

It has been used for centuries to treat various health conditions, including inflammation, cardiovascular disease, and eye problems.

Rutin has antioxidant and anti-inflammatory properties, making it a popular natural remedy for promoting overall well-being and preventing chronic diseases.

3. Quercetin

Cornus mas quercetin is a bioflavonoid compound extracted from the bark of Cornus mas L. trees.

It has been used in traditional medicine for centuries to treat various health issues, including inflammation and cardiovascular diseases. Quercetin exhibits potent antioxidant and anti-inflammatory activities, making it a promising natural remedy for modern medicine.

Its effects on immune function, cancer prevention, and wound healing have also been studied extensively.

4. Kaempferol

Cornus mas kaempferol is a flavonoid compound found in the fruit and bark of the plant.

It has been studied for its potential medicinal properties, including antioxidant and anti-inflammatory effects.

Kaempferol has also been shown to have antibacterial and antifungal activities, making it a promising candidate for the development of new medicines.

5. Isoorientin

Cornus mas, also known as Osage orange, isoorientin is a flavonoid compound extracted from the bark of the Cornus mas tree.

This natural compound has been extensively studied for its potential health benefits, including anti-inflammatory, antioxidant, and antimicrobial properties.

It has also shown to exhibit neuroprotective effects and may have therapeutic applications in the treatment of various diseases such as cancer, cardiovascular disease, and Alzheimer's disease.

6. Orientin

Cornus mas orientin is a bioactive compound found in the fruit of the dogwood plant.

It has been traditionally used in traditional Chinese medicine for its antioxidant and anti-inflammatory properties. Research has shown that orientin may have potential health benefits, including reducing oxidative stress and improving cardiovascular health.

Further studies are needed to fully understand its effects on human health.

7. Cornuside

Cornus mas, also known as Osage Orange, Cornuside is a bioactive compound found in the bark and leaves of this plant.

It has been traditionally used in traditional medicine for its various health benefits, including anti-inflammatory and antioxidant properties.

Research has shown that cornuside exhibits significant inhibitory effects on inflammation and oxidative stress, making it a potential natural remedy for chronic diseases such as cardiovascular disease and cancer.

8. Flavonoids

9. Triterpenes

Cornus mas triterpenes is a class of natural compounds found in the bark and leaves of this deciduous tree.

These triterpenes have been shown to possess anti-inflammatory and antioxidant properties, making them potential therapeutic agents for various diseases.

They have also been demonstrated to exhibit cytotoxic activity against certain cancer cell lines, suggesting their value as leads for the development of new anticancer drugs.

10. Saponins

Cornus mas saponins is a type of natural compound found in its fruit and bark.

These saponins have been shown to possess various biological activities, including antioxidant, anti-inflammatory, and antimicrobial properties.

They have been traditionally used in folk medicine for their alleged benefits on the cardiovascular system, respiratory tract, and digestive system.