Coreopsis lanceolata
Coreopsis lanceolata · Accepted scientific name
Scientific literature: Very Sparse (1 studies) · ★☆☆☆☆
Coreopsis lanceolata is a remarkable plant species known for the diverse therapeutic potential found within its vibrant flowers. Research into its flower methanol extract and EtOAc fraction has revealed a rich profile of bioactive chemicals, including flavonoids, flavanones, and 4-methoxylanceoletin. These compounds contribute to significant biological activities, most notably demonstrating powerful anti-oxidant properties. Furthermore, studies indicate that these extracts can influence cell proliferation and induce apoptosis in targeted cells. These combined characteristics highlight the plant's promising antileukemic activities in medicinal applications.
- Synonyms
- Bidens Lanceolata · Chrysomelea Lanceolata · 11 more
- Common names
- Not available
- Family
- Asteraceae
- Distribution
- Not available
- Plant Parts
- Flower
Classification
Common Names
Coreopsis lanceolata is a versatile plant known by a variety of different names depending on the region and language. It is most commonly referred to simply as Coreopsis or by its formal botanical designation, Coreopsis lanceolata. In some circles, you may encounter the specific variation known as Coreopsis lanceole. The plant also holds charming traditional names, such as Djevojačko oko in certain cultures. Finally, it is affectionately recognized in German-speaking areas as Jungferngesichtchen.
Sources: Catalogue of Life (COL)
Synonyms
Coreopsis lanceolata is a botanical subject that has been documented under several different scientific names throughout history. Taxonomic records show that this plant is associated with the synonym Bidens lanceolata. It has also been referred to in older literature as Chrysomelea lanceolata. Further variations in its classification include the names Coreopsis crassifolia and Coreopsis heterogyna. Finally, the plant is sometimes identified specifically as Coreopsis lanceolata var. angustifolia to denote certain morphological traits.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Coreopsis lanceolata belongs to the vast kingdom Plantae, representing a diverse group of multicellular organisms. Within this kingdom, it is classified under the class Equisetopsida, showcasing its fundamental botanical structures. The plant is further organized into the order Asterales, a lineage known for its distinct floral characteristics. It falls specifically under the family Asteraceae, making it a close relative to many well-known wildflowers. Finally, this species is identified by its unique genus, Coreopsis, which defines its specific botanical identity.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Asterales |
| Family | Asteraceae |
| Genus | Coreopsis |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Coreopsis lanceolata exhibits a diverse geographic range that spans across several key regions of the African continent. Its distribution reaches the Macaronesia islands, including the Azores, extending its presence into unique Atlantic environments. Within mainland Africa, the species is well-established in South Tropical Africa and specifically throughout Zimbabwe. It also thrives across various parts of Southern Africa, including the Northern Provinces and the KwaZulu-Natal region. Furthermore, the plant finds a home in the Western Indian Ocean, notably appearing in Mauritius.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Coreopsis lanceolata is a versatile herb that thrives as a self-supporting plant in various garden settings. This species exhibits a flexible growth habit, typically reaching a maximum height of 1 meter. Depending on its specific environment, the plant's stature can vary significantly. It may grow as low as 0.2 meters or maintain a more substantial presence at a minimum of 0.555 meters. These diverse height ranges allow the plant to adapt beautifully to different landscapes.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Coreopsis lanceolata is a perennial member of the Asteraceae family that has demonstrated significant therapeutic potential in recent scientific studies. Investigations into the yellow flowers of this plant have revealed a high concentration of flavonoids within its methanol extract. Specifically, these compounds have shown a notable antileukemic activity by inhibiting the proliferation of human HL-60 leukemia cells. Researchers successfully isolated rare phytochemicals, such as 4-methoxylanceoletin, which exhibited potent antiproliferative effects during testing. This chemical profile highlights the plant's unique biological properties and its promise as a source of medicinal compounds.
Compounds
Coreopsis lanceolata is a perennial plant belonging to the Asteraceae family that is noted for its rich concentration of various flavonoids. Scientific investigations have identified several specific compounds within the flowers, including the flavonol isoquercetin and the flavonoid astragalin. Phytochemical research further reveals the presence of a flavanone structure within its profile. Notably, the plant contains 4-methoxylanceoletin, a rare flavonoid that has demonstrated potent antiproliferative activity. These diverse chemical constituents contribute to the plant's significant potential in antioxidant and therapeutic applications.
Conditions
Coreopsis lanceolata exhibits significant antioxidant properties by providing radical scavenging activities against reactive oxygen species. The plant's extracts effectively treat $H_2O_2$-induced oxidative stress by inducing the expression of antioxidant enzymes in neuronal cells. It also provides neuroprotection by treating $MPP^+$-induced apoptosis through the regulation of the Bcl-2 family of proteins. Furthermore, the plant treats oxidative stress-induced apoptosis by modulating Bcl-xL, Bax, and caspase-3 expression in PC12 cells. Finally, Coreopsis lanceolata demonstrates pro-inflammatory inhibition effects by suppressing NO formation and decreasing iNOS and COX-2 expression.
Preparations
Coreopsis lanceolata is prepared as a flower methanol extract to investigate its flavonoid profile and antileukemic potential. This methanol extract undergoes further processing to be prepared as an EtOAc fraction. Within this specific EtOAc fraction, the total flavonoid content was measured at 420mg/g. This preparation method allowed researchers to observe the inhibition of cell proliferation in human leukemia HL-60 cells. The resulting EtOAc fraction was also essential for isolating rare flavonoids like 4-methoxylanceoletin.
Parts used
Coreopsis lanceolata is a perennial member of the Asteraceae family that possesses distinct yellow flowers. These floral parts serve as a significant source of various phytochemicals, including rare flavonoids such as flavanones, chalcones, and aurones. Research into the methanol extract of these flowers has revealed a substantial total flavonoid content. Specifically, the presence of compounds like 4-methoxylanceoletin demonstrates potent antiproliferative activity against human leukemia cells. Ultimately, the unique chemical profile found within these flowers distinguishes the plant from other members of its family.