opium-antidote

Combretum micranthum · Accepted scientific name

Scientific literature: Very Sparse (45 studies) · ★☆☆☆☆

Opium-antidote, scientifically known as Combretum micrantum, is a medicinal shrub native to tropical Africa. Renowned in traditional medicine, it is primarily utilized for its potent pharmacological properties. Research highlights its significant potential in treating various ailments, particularly its role in neutralizing certain toxins and supporting holistic healing processes.

Family
Combretaceae
Native range
Africa
Parts used
Leaf
Common names
Opium-Antidote
Scientific synonyms
Bureava Crotonoides · Combretum Parviflorum · 3 more

Names and Synonyms

Common Names

Scientific Names

Accepted name

Combretum micranthum

Synonyms

Regional and Traditional Names

German:

  • Kinkéliba

French:

  • kinkeliba
  • kinkéliba
  • kinkéliba

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. It is further classified within the order Myrtales and the family Combretaceae. Finally, its specific taxonomic placement is within the genus Combretum.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Myrtales
Family Combretaceae
Genus Combretum

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant, Combretum micranthum, is found across several specific regions within West Tropical Africa. Its geographical presence includes the country of Benin, where it grows in local ecosystems. It is also distributed throughout Burkina Faso, contributing to the region's floral diversity. Furthermore, the species can be located in the Gambia and within the borders of Ghana. Finally, its range extends to Guinea-Bissau, marking its presence in the westernmost parts of the continent.

Region Area
West Tropical Africa Benin
West Tropical Africa Burkina
West Tropical Africa Gambia
West Tropical Africa Ghana
West Tropical Africa Guinea-Bissau
West Tropical Africa Guinea
West Tropical Africa Ivory Coast
West Tropical Africa Mali
West Tropical Africa Mauritania
West Tropical Africa Nigeria

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Life history

The life history of Combretum micranthum is characterized by its status as a perennial plant, allowing it to persist through multiple growing seasons within its ecosystem. In terms of its structural growth strategy, the species is classified as a phanerophyte, specifically exhibiting characteristics consistent with both phanerophyte and nanophanerophyte designations, meaning its perennating buds are elevated well above the ground level. This growth form enables the plant to maintain a stable presence in its habitat, utilizing its perennial lifecycle to establish long-term vegetative structures that endure seasonal variations.

Life form :
phanerophyte
Lifecycle :
perennial

Morphology

The morphology of Combretum micranthum is characterized by a woody growth form that primarily presents as a shrub. This plant reaches an average height of approximately 4 meters and exhibits a self-supporting structure, though it can also function as a liana. It is a terrestrial species, existing independently without parasitic or epiphytic dependencies.

Aquatic :
terrestrial
Climber :
liana
Climber :
self-supporting
Epiphyte :
terrestrial
Growth form :
shrub
Parasite :
independent
Plant height mean:
4 m
Woodiness :
woody

Physiology

The physiology of Combretum micranthum is characterized by a standard C3 photosynthetic pathway, meaning it utilizes the Calvin cycle to fix atmospheric carbon dioxide through the enzyme RuBisCO without the specialized carbon-concentrating mechanisms found in C4 or CAM plants. This metabolic strategy typically involves opening stomata during daylight hours to facilitate gas exchange, which influences its transpiration rates and water-use efficiency within its native habitat. Additionally, the plant does not function as a nitrogen fixer, lacking the symbiotic relationships with diazotrophic bacteria in root nodules required to convert atmospheric nitrogen into bioavailable forms, and therefore relies on the uptake of nitrates and ammonium present in the soil substrate to meet its nitrogenous nutritional requirements.

Nitrogen fixer :
no
Photosynthetic pathway :
C3

Reproduction

The reproduction of Combretum micrantum is characterized by the production of seeds that exhibit significant morphological variability in terms of weight. Based on quantitative analysis, the seed mass of this species fluctuates within a specific range, with a minimum recorded mass of 0.01174 g and a maximum mass reaching up to 0.03651 g. On average, the seed mass is approximately 0.027195 g, a metric that reflects the biological investment per reproductive unit within the species.

Seed mass max:
0.03651 g
Seed mass mean:
0.027195 g
Seed mass min:
0.01174 g

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Combretum micranthum has 1 reported plant parts identified across 4 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include leaf.

Plant parts reported in Combretum micranthum
Plant part Supporting sources Consensus
Leaf 4 supporting sources ★★☆☆☆

Leaf

  1. Journal of food and drug analysis
  2. Molecules (Basel, Switzerland)
  3. Journal of ethnopharmacology
  4. Journal of pharmaceutical and biomedical analysis

Chemicals

Combretum micranthum has 16 reported phytochemicals identified across 4 scientific publications and several other databases. The most consistently reported chemicals include Flavonoids, 2,2-Dimethyl-3-[4-(acetyloxy)phenyl]-4-ethyl-2H-1-benzopyran-7-ol acetate, 3-DESHYDROXYSAPPANOL TRIMETHYL ETHER, 4-Hydroxycinnamic acid, 9,13-Di-cis-retinoic acid.

Chemicals reported in Combretum micranthum
Chemical Supporting sources Consensus
Flavonoids 2 supporting sources ★☆☆☆☆
2,2-Dimethyl-3-[4-(acetyloxy)phenyl]-4-ethyl-2H-1-benzopyran-7-ol acetate 1 supporting sources ★☆☆☆☆
3-DESHYDROXYSAPPANOL TRIMETHYL ETHER 1 supporting sources ★☆☆☆☆
4-Hydroxycinnamic acid 1 supporting sources ★☆☆☆☆
9,13-Di-cis-retinoic acid 1 supporting sources ★☆☆☆☆
CALCIUM 1 supporting sources ★☆☆☆☆
Fatty acids 1 supporting sources ★☆☆☆☆
Glyinflanin A 1 supporting sources ★☆☆☆☆
IRON 1 supporting sources ★☆☆☆☆
MAGNESIUM 1 supporting sources ★☆☆☆☆

Flavonoids

  1. Toxicology reports
  2. Chemistry & biodiversity

2,2-Dimethyl-3-[4-(acetyloxy)phenyl]-4-ethyl-2H-1-benzopyran-7-ol acetate

  1. Biotechnologia

3-DESHYDROXYSAPPANOL TRIMETHYL ETHER

  1. Biotechnologia

4-Hydroxycinnamic acid

  1. Biotechnologia

9,13-Di-cis-retinoic acid

  1. Biotechnologia

CALCIUM

  1. Chemistry & biodiversity

Fatty acids

  1. Chemistry & biodiversity

Glyinflanin A

  1. Biotechnologia

IRON

  1. Chemistry & biodiversity

MAGNESIUM

  1. Chemistry & biodiversity

Activities

Combretum micranthum has 10 reported activities identified across 4 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Antidiabetic, Analgesic, Antibacterial, Antihypertensive.

Activities reported in Combretum micranthum
Activity Supporting sources Consensus
Antioxidant 3 supporting sources ★★☆☆☆
Antidiabetic 2 supporting sources ★☆☆☆☆
Analgesic 1 supporting sources ★☆☆☆☆
Antibacterial 1 supporting sources ★☆☆☆☆
Antihypertensive 1 supporting sources ★☆☆☆☆
Antiviral 1 supporting sources ★☆☆☆☆
Anxiolytic 1 supporting sources ★☆☆☆☆
Diuretic 1 supporting sources ★☆☆☆☆
Hepatoprotective 1 supporting sources ★☆☆☆☆
Nephroprotective 1 supporting sources ★☆☆☆☆

Antioxidant

  1. International journal of molecular sciences
  2. Biotechnologia
  3. Chemistry & biodiversity

Antidiabetic

  1. Biotechnologia
  2. Chemistry & biodiversity

Analgesic

  1. Chemistry & biodiversity

Antibacterial

  1. Chemistry & biodiversity

Antihypertensive

  1. Chemistry & biodiversity

Antiviral

  1. Chemistry & biodiversity

Anxiolytic

  1. Chemistry & biodiversity

Diuretic

  1. Plants (Basel, Switzerland)

Hepatoprotective

  1. Chemistry & biodiversity

Nephroprotective

  1. Chemistry & biodiversity

Conditions

Combretum micranthum has 10 reported investigations on conditions identified across 4 scientific publications and several other databases. The most consistently reported conditions include Crohn's disease, Inflammatory bowel diseases, colitis, dermatitis, diuretic.

Conditions investigated for Combretum micranthum
Condition Supporting sources Consensus
Crohn's disease 1 supporting sources ★☆☆☆☆
Inflammatory bowel diseases 1 supporting sources ★☆☆☆☆
Colitis 1 supporting sources ★☆☆☆☆
Dermatitis 1 supporting sources ★☆☆☆☆
Diuretic 1 supporting sources ★☆☆☆☆
Liver diseases 1 supporting sources ★☆☆☆☆
Malaria 1 supporting sources ★☆☆☆☆
Nausea 1 supporting sources ★☆☆☆☆
Osteoporosis 1 supporting sources ★☆☆☆☆
Ulcerative colitis 1 supporting sources ★☆☆☆☆

Crohn's disease

  1. International journal of molecular sciences

Inflammatory bowel diseases

  1. International journal of molecular sciences

Colitis

  1. International journal of molecular sciences

Dermatitis

  1. Journal of ethnobiology and ethnomedicine

Diuretic

  1. Plants (Basel, Switzerland)

Liver diseases

  1. Natural product communications

Malaria

  1. Natural product communications

Nausea

  1. Journal of ethnobiology and ethnomedicine

Osteoporosis

  1. Toxicology reports

Ulcerative colitis

  1. International journal of molecular sciences

Preparations

Combretum micranthum has 6 reported preparations identified across 4 scientific publications and several other databases. The most consistently reported preparations include Herbal tea, aqueous extracts, aqueous leaf extract, aqueous-methanol extracts, extracts obtained in refluxed dichloromethane.

Preparations reported for Combretum micranthum
Preparation Supporting sources Consensus
Herbal tea 1 supporting sources ★☆☆☆☆
Aqueous extracts 1 supporting sources ★☆☆☆☆
Aqueous leaf extract 1 supporting sources ★☆☆☆☆
Aqueous-methanol extracts 1 supporting sources ★☆☆☆☆
Extracts obtained in refluxed dichloromethane 1 supporting sources ★☆☆☆☆
Plant leaves extract 1 supporting sources ★☆☆☆☆

Herbal tea

  1. Journal of food and drug analysis

Aqueous extracts

  1. Toxicology reports

Aqueous leaf extract

  1. Journal of ethnopharmacology

Aqueous-methanol extracts

  1. Biotechnologia

Extracts obtained in refluxed dichloromethane

  1. Journal of pharmaceutical and biomedical analysis

Plant leaves extract

  1. Molecules (Basel, Switzerland)