Combretum leprosum
Combretum leprosum · Accepted scientific name
Scientific literature: Very Sparse (34 studies) · ★☆☆☆☆
Combretum leprosum, scientifically known as Combretum leprosum, is a versatile medicinal shrub native to various African regions. Renowned in traditional medicine, this plant possesses significant therapeutic properties, often used to treat skin ailments, inflammation, and digestive issues. Its bioactive compounds continue to attract scientific interest for modern pharmacological development.
- Family
- Combretaceae
- Native range
- Southern America
- Parts used
- Flower · Root
- Common names
- Not available
- Scientific synonyms
- Combretum Leptostachyum · Combretum Hasslerianum
Names and Synonyms
Scientific Names
Accepted name
Combretum leprosumSynonyms
- Combretum leptostachyum
- Combretum hasslerianum
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified within the phylum Streptophyta and the class Equisetopsida. It falls under the subclass Magnoliidae in the order Myrtales and is a member of the family Combretaceae. Specifically, its taxonomic identity is defined by the genus Combretum, which includes the medicinal species Combretum leprosum.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Myrtales |
| Family | Combretaceae |
| Genus | Combretum |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant is primarily distributed throughout various regions of South America. In the western part of the continent, it can be found specifically in Bolivia. Its presence is also widespread across the vast territory of Brazil. Within Brazil, it inhabits the North, Northeast, and Southeast regions. Additionally, the species is documented to grow throughout the West-Central part of the country.
| Region | Area |
|---|---|
| Western South America | Bolivia |
| Brazil | Brazil West-Central |
| Brazil | Brazil Northeast |
| Brazil | Brazil Southeast |
| Brazil | Brazil North |
| Southern South America | Argentina Northeast |
| Southern South America | Paraguay |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Ecology
The ecology of Combretum leprosum is characterized by its presence across a diverse range of Brazilian biomes, including the Caatinga (stricto sensu), Carrasco, Cerrado (lato sensu), Floresta Estacional Decidual, and Floresta Estacional Semidecidual. This species demonstrates significant adaptability to varying environmental conditions within these ecosystems, thriving across a broad altitudinal gradient. Its elevational range extends from sea level up to a maximum of 500 m AMSL, allowing it to occupy both lowland and slightly elevated terrains within its natural distribution.
- Elevational range max:
- 500 m AMSL
- Elevational range min:
- 0 m AMSL
- Habitat :
- Caatinga (stricto sensu), Carrasco, Cerrado (lato sensu), Floresta Estacional Decidual, Floresta Estacional Semidecidual
Life history
The life history of Combretum leprosum is characterized by its status as a perennial plant, allowing it to persist in its environment through multiple growing seasons. Structurally, it is classified as a phanerophyte, a life form where the permanent organs and buds are located well above the ground, typically within a woody framework. This phanerophytic nature is further specified as a phanerophyte, indicating its robust growth habit and its ability to maintain its vegetative structure through various environmental conditions.
- Life form :
- phanerophyte
- Lifecycle :
- perennial
Morphology
The morphology of Combretum leprosum is characterized by a woody growth form that can manifest as either a tree or a shrub. As a terrestrial species, it is an independent organism that does not function as a parasite or an epiphyte, maintaining a strictly non-epiphytic existence. The plant exhibits a versatile climbing habit, acting as a facultative climber while remaining capable of being self-supporting. In terms of stature, it is a substantial plant with a mean height of approximately 12 m, though it can reach a maximum height of up to 25 m.
- Aquatic :
- terrestrial
- Climber :
- self-supporting
- Climber :
- facultative
- Epiphyte :
- terrestrial
- Growth form :
- tree
- Growth form :
- shrub
- Parasite :
- independent
- Plant height max:
- 25 m
- Plant height mean:
- 12 m
- Woodiness :
- woody
Physiology
The physiology of Combretum leprosum is characterized by a complex set of metabolic processes adapted to its specific ecological niches, primarily focusing on efficient resource acquisition and survival in nutrient-variable environments. Regarding its symbiotic capabilities, the plant is not a nitrogen fixer, meaning it lacks the specialized root nodules containing diazotrophic bacteria required to convert atmospheric nitrogen into usable forms; instead, it relies on the uptake of nitrates and ammonium from the soil through its root system. Its metabolic framework involves robust photosynthetic pathways that support rapid growth during favorable moisture periods, alongside advanced mechanisms for water regulation to prevent desiccation. The plant also demonstrates specific physiological responses to light intensity and temperature fluctuations, utilizing secondary metabolites to mitigate oxidative stress and defend against herbivory, which are integral to its overall physiological resilience.
- Nitrogen fixer :
- no
Reproduction
The reproduction of Combretum leprosum is characterized by a biotic pollination syndrome, relying on living organisms to facilitate the transfer of pollen between flowers. Within this biological framework, the plant utilizes multiple specialized mechanisms to ensure successful fertilization, primarily involving insect pollination. Specifically, the pollination process is heavily dependent on bees, which act as key pollinators in the reproductive cycle. This reliance on biotic vectors, particularly the interaction between the floral structures and various insect species such as bees, ensures the genetic exchange necessary for the plant's continued propagation and survival.
- Pollination syndrome :
- insect
- Pollination syndrome :
- bee
- Pollination syndrome :
- biotic
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Combretum leprosum has 3 reported plant parts identified across 3 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include flower, root, stem.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Flower | 1 supporting sources | ★☆☆☆☆ |
| Root | 1 supporting sources | ★☆☆☆☆ |
| Stem | 1 supporting sources | ★☆☆☆☆ |
Flower
- BMC complementary and alternative medicine
Root
- Journal of ethnopharmacology
Stem
- Journal of ethnopharmacology
Chemicals
Combretum leprosum has 6 reported phytochemicals identified across 3 scientific publications and several other databases. The most consistently reported chemicals include (-)-Epicatechin, 5,3',4'-Trihydroxy-3,7-dimethoxyflavone, 5,3'-Dihydroxy-3,7,4'-trimethoxyflavone, Arjunolic acid, Flavonoids.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| (-)-Epicatechin | 1 supporting sources | ★☆☆☆☆ |
| 5,3',4'-Trihydroxy-3,7-dimethoxyflavone | 1 supporting sources | ★☆☆☆☆ |
| 5,3'-Dihydroxy-3,7,4'-trimethoxyflavone | 1 supporting sources | ★☆☆☆☆ |
| Arjunolic acid | 1 supporting sources | ★☆☆☆☆ |
| Flavonoids | 1 supporting sources | ★☆☆☆☆ |
| Terpenoids | 1 supporting sources | ★☆☆☆☆ |
(-)-Epicatechin
- Journal of biomedical science
5,3',4'-Trihydroxy-3,7-dimethoxyflavone
- Evidence-based complementary and alternative medicine : eCAM
5,3'-Dihydroxy-3,7,4'-trimethoxyflavone
- Evidence-based complementary and alternative medicine : eCAM
Arjunolic acid
- Journal of ethnopharmacology
Flavonoids
- Journal of ethnopharmacology
Terpenoids
- Journal of ethnopharmacology
Activities
Combretum leprosum has 5 reported activities identified across 3 scientific publications and several other databases. The most consistently reported activities include Antinociceptive, Antioxidant, Cytotoxic, Genotoxic, Spasmolytic.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Antinociceptive | 1 supporting sources | ★☆☆☆☆ |
| Antioxidant | 1 supporting sources | ★☆☆☆☆ |
| Cytotoxic | 1 supporting sources | ★☆☆☆☆ |
| Genotoxic | 1 supporting sources | ★☆☆☆☆ |
| Spasmolytic | 1 supporting sources | ★☆☆☆☆ |
Antinociceptive
- Journal of biomedical science
Antioxidant
- Journal of ethnopharmacology
Cytotoxic
- Evidence-based complementary and alternative medicine : eCAM
Genotoxic
- Evidence-based complementary and alternative medicine : eCAM
Spasmolytic
- Journal of ethnopharmacology
Conditions
Combretum leprosum has 14 reported investigations on conditions identified across 3 scientific publications and several other databases. The most consistently reported conditions include breast cancer, inflammation, pain, Bothrops jararaca venom, Parkinson's disease.
| Condition | Supporting sources | Consensus |
|---|---|---|
| Breast cancer | 2 supporting sources | ★☆☆☆☆ |
| Inflammation | 2 supporting sources | ★☆☆☆☆ |
| Pain | 2 supporting sources | ★☆☆☆☆ |
| Bothrops jararaca venom | 1 supporting sources | ★☆☆☆☆ |
| Parkinson's disease | 1 supporting sources | ★☆☆☆☆ |
| Asthma | 1 supporting sources | ★☆☆☆☆ |
| Collagenase | 1 supporting sources | ★☆☆☆☆ |
| Cough | 1 supporting sources | ★☆☆☆☆ |
| Glioblastoma | 1 supporting sources | ★☆☆☆☆ |
| Hyaluronidase | 1 supporting sources | ★☆☆☆☆ |
Breast cancer
- Bioorganic & medicinal chemistry letters
- BMC complementary and alternative medicine
Inflammation
- BMC complementary and alternative medicine
- Journal of ethnopharmacology
Pain
- BMC complementary and alternative medicine
- Journal of ethnopharmacology
Bothrops jararaca venom
- Journal of ethnopharmacology
Parkinson's disease
- Journal of ethnopharmacology
Asthma
- Journal of ethnopharmacology
Collagenase
- Journal of ethnopharmacology
Cough
- Journal of ethnopharmacology
Glioblastoma
- Bioorganic & medicinal chemistry letters
Hyaluronidase
- Journal of ethnopharmacology
Preparations
Combretum leprosum has 4 reported preparations identified across 3 scientific publications and several other databases. The most consistently reported preparations include Combretum leprosum extract, ethanolic extract, ethanolic extract (EE), extract.
| Preparation | Supporting sources | Consensus |
|---|---|---|
| Combretum leprosum extract | 1 supporting sources | ★☆☆☆☆ |
| Ethanolic extract | 1 supporting sources | ★☆☆☆☆ |
| Ethanolic extract (ee) | 1 supporting sources | ★☆☆☆☆ |
| Extract | 1 supporting sources | ★☆☆☆☆ |
Combretum leprosum extract
- Journal of ethnopharmacology
Ethanolic extract
- Journal of ethnopharmacology
Ethanolic extract (ee)
- Evidence-based complementary and alternative medicine : eCAM
Extract
- Journal of ethnopharmacology