Clusia alata
Clusia alata · Accepted scientific name
Scientific literature: Very Sparse (1 studies) · ★☆☆☆☆
Clusia alata is a tropical plant species that has become a subject of interest in pharmacological research. Recent studies have focused on evaluating the biological impact of its crude extract on cellular structures. Investigations have specifically targeted the potential mutagenic activities present within the plant's chemical constituents. Researchers utilize these preparations to observe whether exposure leads to significant genetic damage. Specifically, the analysis aims to identify the presence and extent of chromosome aberrations in treated cells.
- Synonyms
- Not available
- Common names
- Not available
- Family
- Clusiaceae
- Distribution
- Not available
- Plant Parts
- Not available
Classification
Common Names
Clusia alata is a striking tropical plant frequently recognized by its distinctive, large, and leathery leaves. In many regions, this beautiful species is affectionately known by the common name Chagula. It is widely admired for its ability to thrive in various environments, making it a popular choice for lush landscapes. The plant's unique aesthetic adds a sense of prehistoric charm to any garden or indoor collection. Understanding its common identity helps enthusiasts better connect with this resilient and elegant greenery.
Sources: Catalogue of Life (COL)
Taxonomy
Clusia alata belongs to the vast kingdom Plantae, marking its place among the diverse living organisms on Earth. Within this biological hierarchy, the species is classified under the class Equisetopsida and the order Malpighiales. It finds its specific botanical home within the family Clusiaceae. Furthermore, this plant is a distinguished member of the genus Clusia. Through these structured relationships, scientists can accurately map its evolutionary lineage and biological characteristics.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Malpighiales |
| Family | Clusiaceae |
| Genus | Clusia |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Clusia alata is a notable plant species primarily found throughout the diverse landscapes of Southern America. Its natural distribution spans several key regions, including the lush territories of Northern South America. Within this area, the species is specifically documented across the country of Venezuela. Furthermore, it thrives in the Western South American regions of both Colombia and Ecuador. This widespread presence highlights the plant's ability to adapt to various ecological niches across the continent.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Clusia alata is a self-supporting plant that adopts the impressive growth form of a tree. This species typically reaches a minimum height of 5 meters as it matures. Under optimal conditions, it can continue to climb until it achieves a maximum height of 18 meters. Such significant stature makes it a commanding presence within its natural habitat.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Clusia alata has been identified as having significant mutagenic activity according to recent in vivo research. Studies utilizing comet and chromosome aberration assays demonstrated that crude extracts can induce DNA damage in peripheral blood leukocytes. Specifically, at high doses of 2000 mg/kg, the extract caused a notable increase in genetic damage after 24 hours. Furthermore, the plant exhibited mutagenic effects in bone marrow cells when administered at doses of 1500 mg/kg and 2000 mg/kg. These findings suggest that while the plant is a potential medicinal resource, its acute consumption at high concentrations carries genotoxic risks.
Compounds
Conditions
Clusia alata does not treat chromosome aberrations, but rather induces a significant increase in them at specific doses. The extract also does not treat damage to DNA, as the comet assay showed it causes an increase in DNA damage in peripheral blood leukocytes. Instead of treating mutagenic effects, the acute consumption of high concentrations of the plant produces these effects in bone marrow cells. Consequently, the research indicates that the plant's extract is genotoxic rather than therapeutic for these specific conditions. The findings demonstrate that the plant contributes to these cellular issues rather than providing a treatment for them.
Preparations
Clusia alata is prepared as a crude extract to evaluate its potential mutagenic effects in biological studies. This specific extract was utilized in short-term in vivo assays to test for genotoxicity in mice. Researchers administered the crude form of the plant at various doses to observe its impact on peripheral leukocytes and bone marrow cells. The study focused on how the prepared extract influenced DNA damage and chromosome aberrations. Ultimately, the results indicated that the crude extract can induce mutagenic effects when consumed at high concentrations.