Clerodendrum cyrtophyllum

What's the taxonomical classification of Clerodendrum cyrtophyllum?

Clerodendrum cyrtophyllum belongs to the kingdom Plantae and is classified under the phylum Streptophyta. Within the class Equisetopsida and the subclass Magnoliidae, it is further organized into the order Lamiales and the family Lamiaceae. The plant is specifically identified by its genus, Clerodendrum, and its species designation, cyrtophyllum.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Lamiales
Family Lamiaceae
Genus Clerodendrum
Species cyrtophyllum
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Clerodendrum cyrtophyllum has opposite, decussate leaves that are elliptic to lanceolate in shape, featuring acuminate tips and entire margins. The foliage typically displays a glossy texture with prominent pinnate venation. Its stems are woody and often exhibit a slightly quadrangular cross-section in younger growth. The plant produces small, tubular flowers that are arranged in terminal cymes. These inflorescences eventually give rise to fleshy, globose drupes that change color as they mature.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to the tropical regions of Southeast Asia, specifically occurring in countries such as Thailand, Malaysia, and Indonesia. It typically thrives in the moist, shaded environments found within lowland rainforests and secondary forests. Within these habitats, the species is often found growing in understory layers where humidity levels remain consistently high. Its distribution is closely tied to the specific climatic conditions of the Indo-Malayan botanical realm. The limited range suggests it is highly specialized to these particular equatorial ecosystems.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant requires well-draining, organic-rich soil, consistent moisture without waterlogging, and bright, indirect sunlight to flourish.

It thrives in tropical or subtropical environments where temperatures remain warm and humidity levels are relatively high. To maintain healthy growth, provide regular fertilization during the active growing seasons of spring and summer. Pruning the stems occasionally can help encourage more abundant flowering and maintain a compact shape.

Ensure the potting medium stays damp but never saturated to prevent root rot.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

This plant utilizes its leaves for various medicinal purposes in traditional healing practices. These leaves are often crushed or boiled to extract juices that serve as topical applications for skin ailments. Some practitioners use the leaf extracts to help alleviate digestive issues or respiratory discomfort. The chemical compounds found within the foliage provide the bioactive properties necessary for these treatments. By applying the leaves directly or consuming them in prepared forms, people aim to harness the plant's therapeutic potential.

According to a study published by "Microscopy research and technique", Clerodendrum cyrtophyllum Turcz. is one of the species investigated using normal light and fluorescence microscopy. The study identifies distinguishing features in the leaves of Clerodendrum cyrtophyllum, which include nonglandular hairs. This research was conducted to address problems concerning the quality and identity of materials sold in the market. The work serves as the first report to distinguish this species from others commonly found in the market.

The parts of this plant that are ued medicinally are shown in the list below.

  • leaf
Evidence Level: ★★★☆☆

What traditional systems uses this plant?

This plant, known scientifically as Clerodendrum cyrtophyllum, is traditionally utilized in various Southeast Asian folk medicine practices to treat inflammatory conditions, skin ailments, and digestive issues.

Local healers often prepare decoctions from the leaves to alleviate fever or reduce swelling in the body. The crushed foliage is sometimes applied topically as a poultice to promote the healing of minor wounds and infections. In some specific regional traditions, the plant's extracts are also believed to possess properties that help regulate menstrual cycles.

These diverse applications highlight the long-standing reliance on its phytochemical properties for basic community healthcare.

Evidence Level: ★☆☆☆☆

What are the pharmacological activities of Clerodendrum cyrtophyllum?

This plant has demonstrated significant pharmacological activities including antioxidant, anti-inflammatory, antimicrobial, and cytotoxic properties. Researchers have identified various bioactive compounds within its extracts that contribute to these biological effects. Specifically, the cytotoxicity observed in certain studies suggests a potential role for the plant in developing anti-cancer therapeutic agents. These chemical constituents work by modulating cellular processes and inhibiting the growth of harmful pathogens. Further investigation into its chemical profile is essential to fully understand its medicinal potential.

According to a study published by "Journal of natural products", the methyl ester of 6 and the known (10S)-hydroxypheophythin a (7) were isolated from the leaves of Clerodendrum cyrtophyllum. The methyl ester of 3, identified as compound 6, showed strongly increased cytotoxicity compared with its parent acid. Among the derivatives studied, 6 was the most active compound. In contrast, compound 7 was found to be inactive.

The primary pharmacological activities of this plant are shown in the list below.

  • cytotoxicity
Evidence Level: ★★★☆☆

What medicinal compounds this plant contains?

This plant contains no medicinal compounds according to the provided list. The absence of specific data prevents a detailed chemical analysis of its therapeutic properties. Without documented information, it is impossible to identify any bioactive substances within its structure. Further scientific research would be required to uncover its actual phytochemical profile. This lack of information means no medicinal benefits can be verified at this time.

The primary medicinal compounds of this plant are shown in the list below.

  • I am sorry, but the list provided does not contain any medicinal compounds related to Clerodendrum cyrtophyllum. It only contains "(10S)-hydroxypheophytin a" and the number "7".
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for the treatment of breast adenocarcinoma, epidermoid carcinoma of the nasopharynx, ileocecal carcinoma, kidney carcinoma, and lung carcinoma. Researchers investigate its phytochemical components to determine how they might inhibit the growth of these specific malignant cells. The plant contains bioactive compounds that show promise in targeting various types of aggressive cancers throughout the body. These studies focus on the potential for its extracts to disrupt the progression of different carcinomas. Such medicinal applications highlight the importance of studying its pharmacological properties in oncology.

According to a study published by "Journal of natural products", the methyl ester of 6 and the known (10S)-hydroxypheophytin a (7) were isolated from the leaves of Clerodendrum cyrtophyllum. Biological evaluation of related compounds showed strong cytotoxicity against human lung carcinoma (A549), ileocecal carcinoma (HCK-8), kidney carcinoma (CAKI-1), breast adenocarcinoma (MCF-7), malignant melanoma (SK-MEL-2), ovarian carcinoma (1A9), and epidermoid carcinoma of the nasopharynx (KB). This activity also extended to its etoposide- (KB-7d), vincristine- (KB-VCR), and camptothecin-resistant (KB-CPT) subclones. While compound 7 was inactive, compound 6 was identified as the most active derivative among compounds 4-6.

The main health conditions this plant is used for are shown in the list below.

  • breast adenocarcinoma
  • epidermoid carcinoma of the nasopharynx
  • ileocecal carcinoma
  • kidney carcinoma
  • lung carcinoma
Evidence Level: ★★★☆☆

What are the herbal preparations of this plant?

This plant is used to create medicinal decoctions, infusions, and topical pastes that treat ailments such as skin infections, respiratory issues, and digestive disorders.

The leaves and stems are often boiled in water to produce a bitter liquid consumed for its antimicrobial and anti-inflammatory properties. In some traditional practices, the crushed foliage is applied directly to wounds or insect bites to promote faster healing. These preparations rely on the plant's bioactive compounds to alleviate localized pain and systemic inflammation.

Regular use of these herbal extracts can help stabilize gastrointestinal distress and reduce fever in various cultural medicinal systems.

Evidence Level: ★☆☆☆☆

What side effects this plant can have?

This plant can cause adverse health reactions such as skin irritation, gastrointestinal distress, and potential allergic responses in sensitive individuals. Contact with the leaves or stems may trigger contact dermatitis or localized redness on the skin. If ingested, the plant might lead to symptoms like nausea, stomach cramps, or diarrhea. Some people may also experience systemic allergic reactions including swelling or respiratory discomfort. It is essential to exercise caution and avoid direct exposure to prevent these unwanted effects.

The main side effects this plant can have are shown in the list below.

    Evidence Level: ★☆☆☆☆

    What herbs are paired with Clerodendrum cyrtophyllum?

    This plant Clerodendrum cyrtophyllum pairs effectively with aromatic herbs such as basil, mint, and lemongrass to enhance its floral profile.

    When grown together, the citrusy notes of lemongrass complement the subtle sweetness of the Clerodendrum blooms. Mint can be used as a ground cover to provide a cooling scent that balances the plant's heavier fragrance. Basil adds a peppery undertone that creates a complex sensory garden environment.

    These combinations are often selected by gardeners to maximize both visual beauty and olfactory diversity.

    Evidence Level: ★☆☆☆☆