Cleome dodecandra
Cleome dodecandra · Accepted scientific name
Scientific literature: Very Sparse (2 studies) · ★☆☆☆☆
Cleome dodecandra is a fascinating botanical species that has gained significant attention in pharmacological research. This plant is particularly noted for its potent cytotoxic properties when studied in biological systems. Among its most important bioactive constituents is the chemical compound known as polacandrin. Recent scientific investigations have highlighted the plant's promising antitumor activities against various cell lines. Consequently, it represents a valuable subject for the development of new therapeutic agents in oncology.
- Synonyms
- Polanisia Graveolens Var. Simplex · Polanisia Graveolens Var. Glabriuscula · 15 more
- Common names
- Not available
- Family
- Cleomaceae
- Distribution
- Not available
- Plant Parts
- Not available
Classification
Synonyms
Cleome dodecandra is a botanical species known to be associated with several different scientific names. Throughout various classifications, it has been identified by synonyms such as Cleome epilobioides and Cleome graveolens. Taxonomic shifts have also linked it to names like Cleome lusitanica and Gynandropsis viscosa. Additionally, historical records may list the plant under the name Jacksonia dodecandra. Understanding these various synonyms is essential for accurate identification and research within the field of botany.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Cleome dodecandra is a fascinating biological specimen that belongs to the vast kingdom Plantae. Within this diverse kingdom, the plant is classified under the class Equisetopsida. It further falls into the order Brassicales, which helps scientists understand its evolutionary lineage. As a member of the genus Cleome, it shares unique characteristics with its close botanical relatives. Finally, its specific placement within the family Cleomaceae defines its unique botanical identity.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Brassicales |
| Family | Cleomaceae |
| Genus | Cleome |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Cleome dodecandra is a widely distributed species with a presence stretching across several diverse continents. In Asia, its range extends through temperate regions including the Russian Far East and Primorye. The plant also establishes itself within Europe, specifically across Middle Europe and throughout Germany. Its reach into North America is significant, with documented populations in Eastern Canada spanning Ontario and Québec. Furthermore, its distribution continues southward into the northeastern regions of Mexico.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Cleome dodecandra is a self-supporting herb characterized by its compact and sturdy growth form. This plant typically reaches a maximum height of 0.9 meters, though it can grow as short as 0.3 meters depending on its environment. Its upright structure allows it to thrive effectively without the need for external support. Overall, these dimensions make it a versatile addition to various botanical landscapes.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Cleome dodecandra has demonstrated significant medicinal potential through its observed biological activities. Research indicates that the plant possesses notable antitumor properties that may aid in cancer treatment. Specifically, the isolation of certain compounds from the species reveals a potent cytotoxic effect against various tumor cell lines. Studies have shown that these substances effectively target cells such as KB, P-388, and RPMI-7951. Consequently, the plant remains a subject of interest for those investigating new chemical structures for pharmaceutical development.
Compounds
Cleome dodecandra serves as a significant natural source for the discovery of unique bioactive compounds. Researchers have successfully isolated a new dammarane triterpene known as polacandrin from this specific plant species. Through the use of advanced spectroscopic methods and X-ray analysis, the precise chemical structure and stereochemistry of the molecule were established. Studies indicate that polacandrin possesses remarkable cytotoxic properties against various cancer cell lines. These findings highlight the medicinal potential of the chemical constituents found within the plant.
Conditions
Cleome dodecandra exhibits significant antitumor properties through the cytotoxic action of its constituent polacandrin. This plant derivative effectively treats KB tumor cells with an ED50 of 0.60 microgram/ml. It also demonstrates potent efficacy against P-388 tumor cells, yielding an ED50 of 0.90 microgram/ml. Furthermore, the substance provides treatment for RPMI-7951 tumor cells at an ED50 of 0.62 microgram/ml. These specific values highlight the high potency of the compounds derived from the plant against various cancer cell lines.