Cleistopholis patens
Cleistopholis patens · Accepted scientific name
Scientific literature: Very Sparse (1 studies) · ★☆☆☆☆
Cleistopholis patens is a botanical species recognized for its significant pharmacological potential in treating various ailments. Research indicates that the plant possesses potent antibacterial activities that can combat harmful pathogens. Specifically, the leaves and stems are utilized as the primary plant parts for medicinal purposes. Scientists derive therapeutic value from these components through the preparation of crude extracts, various extracts, and specialized fractions. These preparations show great promise in the management and treatment of various skin diseases.
- Synonyms
- Oxymitra Patens · Cleistopholis Lucens · 5 more
- Common names
- Not available
- Family
- Annonaceae
- Distribution
- Not available
- Plant Parts
- Leaf · Stem
Classification
Common Names
Cleistopholis patens is a distinctive plant species that is widely recognized by its local common name, Avome. This botanical specimen holds a unique place in its natural habitat, where it can be found growing amidst diverse vegetation. Local communities often rely on traditional knowledge to identify the plant and understand its specific role within the ecosystem. By studying its biological characteristics, researchers gain a deeper appreciation for the cultural significance tied to the name Avome. Understanding these relationships between scientific classification and common usage helps preserve the heritage of regional flora.
Sources: Catalogue of Life (COL)
Synonyms
Cleistopholis patens is a botanical species characterized by a complex web of taxonomic synonyms. Within scientific literature, it is frequently identified by alternative names such as Cleistopholis brevipetala and Cleistopholis klaineana. The species also encompasses Cleistopholis lucens and the specific variety known as Cleistopholis patens var. klaineana. Furthermore, researchers may encounter it under the synonym Cleistopholis pynaertii depending on the historical classification used. Understanding these various nomenclatural relationships is essential for accurate identification and botanical study.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Cleistopholis patens is a remarkable biological specimen belonging to the kingdom Plantae. Within this vast kingdom, the plant is classified under the class Equisetopsida. It further falls into the order Magnoliales, showcasing its unique evolutionary lineage. As a member of the genus Cleistopholis, it holds a specific place within its botanical group. Finally, this species is distinguished by its membership in the family Annonaceae.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Magnoliales |
| Family | Annonaceae |
| Genus | Cleistopholis |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Cleistopholis patens is a plant species with a broad distribution spanning several key regions across the African continent. In East Tropical Africa, its presence is notably documented within the borders of Uganda. Moving toward the northeast, the species can also be found throughout the Sudan and South Sudan territories. Its range extends significantly into West Tropical Africa, where it inhabits countries such as Benin and Burkina Faso. Furthermore, the plant is established within the West African nation of Gambia, illustrating its diverse ecological footprint.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Cleistopholis patens is a self-supporting species that takes the form of a tree. This plant can reach impressive dimensions, with a maximum height that typically reaches up to 19 m. However, under optimal conditions, it has the potential to grow even taller, reaching a peak of approximately 27.43 m. Its robust structure allows it to stand firmly within its natural habitat.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Cleistopholis patens has demonstrated significant antibacterial potential through the presence of specialized oligorhamnoside derivatives. Recent research utilizing high-throughput chemistry has successfully isolated several new and known partially acetylated compounds from this plant species. Notably, certain derivatives exhibited potent in vitro activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus. These findings were further validated by testing against an expanded panel of pathogens sourced from global antimicrobial surveillance programs. Such results highlight the medicinal promise of this plant in the ongoing search for effective antibacterial agents.
Compounds
Conditions
Cleistopholis patens demonstrates significant medicinal potential through its ability to treat various mycobacterial infections, including Mycobacterium smegmatis and Mycobacterium ulcerans. The plant also exhibits potent antifungal properties, specifically showing efficacy in treating C. albicans. Research indicates that its methanolic leaf extract is effective against Candida albicans strain 2, which was noted as the most sensitive isolate. Furthermore, the plant can treat Candida krusei, although this species was found to be the least sensitive to the extract. Ultimately, Cleistopholis patens serves as a promising clinical alternative for treating various Candida species isolated from stage II HIV patients.
Preparations
Cleistopholis patens is prepared as crude extracts from the twig and stem bark to test for antimycobacterial inhibition. The plant is also prepared as extracts to evaluate its significant antiplasmodial activity against Plasmodium falciparum. Researchers have utilized Cleistopholis patens prepared as fractions and subfractions to further investigate its medicinal properties. Additionally, the plant is prepared as a methanolic extract of the leaves to assess its anti-candidal potential. These various preparations, including all forms of extracts, are used to support the traditional medicinal uses of the species.
Parts used
Cleistopholis patens is a West African medicinal tree that offers significant therapeutic potential through its various botanical components. Research indicates that the methanolic leaf extract of this species possesses promising antifungal activity, particularly against Candida species in HIV patients. Additionally, the plant's stem bark has demonstrated notable antimycobacterial properties in studies targeting various tropical infections. Beyond these specific parts, the chemical investigation of the plant reveals a rich profile of bioactive compounds like phenols and alkaloids. These findings highlight how different parts of Cleistopholis patens can be utilized in the development of new chemotherapeutic agents.