Clausena lenis
Clausena lenis · Accepted scientific name
Scientific literature: Very Sparse (2 studies) · ★☆☆☆☆
Clausena lenis is a botanical species that has garnered significant scientific interest due to its diverse biological potential. Research has specifically highlighted its promising antiproliferative and neuroprotective activities, suggesting applications in medicinal studies. Investigations into this plant utilize various components, most notably the stem and the leaf. Studies are conducted across multiple developmental stages, including the use of seeds, 1-week-old seedlings, and seed explants. Furthermore, researchers employ specialized shoot-tip-deprived explants to explore the plant's complex physiological properties.
- Synonyms
- Clausena Kerrii
- Common names
- Not available
- Family
- Rutaceae
- Distribution
- Not available
- Plant Parts
- Stem · Leaf
Classification
Common Names
Clausena lenis is a versatile plant that is recognized by several different common names depending on the region. It is frequently referred to as 光滑黄皮, a name that highlights its distinct physical characteristics. In other local contexts, you may encounter it known as 小麻木. Some people also identify the species by its foliage, calling it 黄皮叶. Understanding these various names is essential for anyone looking to identify this specific plant in the wild.
Sources: Catalogue of Life (COL)
Synonyms
Clausena lenis is a botanical species that is frequently identified in scientific literature through its synonym, Clausena kerrii. While these two names refer to the same plant, the shift in nomenclature reflects evolving taxonomic classifications within the genus. Researchers and botanists often encounter both terms when navigating historical archives and modern databases. Understanding this relationship is essential for maintaining accuracy in ecological studies and plant identification. Consequently, recognizing Clausena kerrii as an alternative name ensures that data remains consistent across different biological contexts.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Clausena lenis belongs to the vast kingdom Plantae, serving as a distinct representative of the natural world. Within this kingdom, the species is classified under the class Equisetopsida. It further falls into the order Sapindales, a group that links it to many other diverse flowering plants. As a member of the genus Clausena, it shares specific morphological traits with its close botanical relatives. Finally, its placement within the family Rutaceae highlights its unique characteristics among citrus-related species.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Sapindales |
| Family | Rutaceae |
| Genus | Clausena |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Clausena lenis exhibits a broad geographical presence across various regions of Asia. In temperate zones, the species is widely distributed throughout mainland China, including the South-Central and Southeast regions. Its reach extends southward to the tropical island of Hainan, demonstrating significant adaptability to different climates. Beyond China, the plant thrives in the tropical landscapes of Indo-China, specifically within the borders of Laos. Furthermore, its natural habitat encompasses parts of Thailand, marking it as a significant species within the Asian flora.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Clausena lenis is a self-supporting plant that maintains its own structural integrity without the need for external support.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Clausena lenis has emerged as a significant botanical source for bioactive compounds with diverse therapeutic potential. Phytochemical investigations of its stems and leaves have led to the isolation of unique furanocoumarins and carbazole alkaloids. Specifically, these compounds demonstrate notable antiproliferative activities against several human cancer cell lines. Furthermore, the plant's secondary metabolites exhibit significant neuroprotective effects by preventing cell death in human neuroblastoma models. These dual capabilities highlight the medicinal importance of Clausena lenis in both oncology and neurology research.
Compounds
Conditions
Clausena lenis contains several carbazole alkaloids that demonstrate significant neuroprotective activities. These compounds were isolated from both the stems and leaves of the plant to evaluate their therapeutic potential. Specifically, the isolated alkaloids effectively treat 6-hydroxydopamine induced cell death within human neuroblastoma SH-SY5Y cells. Testing in vitro revealed that these substances possess potent effects, with EC50 values ranging from 0.68 to 18.76 μM. This evidence highlights the plant's ability to mitigate cellular damage caused by 6-hydroxydopamine.
Preparations
Clausena lenis is prepared as a seed for initial sterilization and germination studies. Various forms of the plant are utilized for tissue culture, including seed explants and stem-node segments. Researchers also use 1-week-old seedling explants to induce abundant callus when cultured on MS medium. For the rooting process, the plant is prepared as shoot-tip-deprived explants to maximize effectiveness. These diverse preparation methods support the successful in vitro propagation and conservation of the species.
Parts used
Clausena lenis is a plant of significant pharmacological interest due to the diverse bioactive compounds found within its various structures. Scientific investigations have specifically focused on the stems of the plant to isolate prenylated coumarins with potential anti-inflammatory and anti-HIV properties. Furthermore, researchers have utilized both the stems and leaves of the species to identify furanocoumarins that exhibit antiproliferative activities against several human cancer cell lines. The leaves and stems have also proven to be a rich source of neuroprotective carbazole alkaloids capable of protecting against cell death. Ultimately, the chemical profiles extracted from these specific parts highlight the plant's immense potential for pharmaceutical development.