Clausena emarginata
Clausena emarginata · Accepted scientific name
Scientific literature: Very Sparse (1 studies) · ★☆☆☆☆
Clausena emarginata is a botanical species that has garnered significant scientific interest due to its diverse biological potential. Research has specifically focused on evaluating the medicinal properties found within its leaf and stem components. By utilizing a 90% ethanol extract, scientists are able to isolate key bioactive compounds from these plant parts. Current studies highlight the notable antiproliferative activities demonstrated by these concentrated extracts. Such findings suggest that this plant may hold valuable promise for future pharmacological developments in cancer research.
- Synonyms
- Not available
- Common names
- Not available
- Family
- Rutaceae
- Distribution
- Asia-Tropical
- Plant Parts
- Leaf · Stem
Classification
Common Names
Clausena emarginata is a distinctive plant species that is recognized by various regional identifiers. In certain areas, it is widely known by its common name ショウコウヒ. It is also frequently referred to as 小黄皮, reflecting its cultural or linguistic roots. These different names highlight the diverse ways the plant is categorized across various communities. Understanding these synonyms is essential for anyone studying the botanical diversity of the species.
Sources: Catalogue of Life (COL)
Taxonomy
Clausena emarginata is a fascinating botanical specimen belonging to the vast kingdom Plantae. Within this diverse kingdom, the plant is classified under the class Equisetopsida. It specifically falls into the order Sapindales, a group known for its distinct evolutionary characteristics. Further narrowing its identity, the species is a member of the genus Clausena. Finally, it is a distinguished representative of the Rutaceae family, often recognized for its aromatic qualities.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Sapindales |
| Family | Rutaceae |
| Genus | Clausena |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Clausena emarginata is a plant species primarily found within the diverse landscapes of the Asia-Temperate region. Its geographic range is specifically concentrated within the vast borders of China. Within this nation, the species can be identified throughout the South-Central territories. Additionally, its distribution extends into the lush environments of Southeast China. These localized habitats define the natural occurrence and ecological presence of this particular plant.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Biological Activities
Clausena emarginata has emerged as a significant subject of study due to the presence of potent carbazole alkaloids in its stems and leaves. Recent phytochemical investigations led to the isolation of a novel compound, clausemargine A, alongside several known analogues. These isolated substances were rigorously evaluated for their ability to inhibit cell growth across five distinct human cancer cell lines. The results demonstrated that compounds 1 through 12 exhibit significant antiproliferative activities in vitro. With IC50 values ranging from 0.28 to 15.18 μM, these findings highlight the plant's therapeutic potential in oncology research.
Compounds
Conditions
Clausena emarginata contains carbazole alkaloids that demonstrate significant antiproliferative activities against several human cancer cell lines. Specifically, the plant extracts show the ability to treat A-549 cells through the action of isolated compounds. Research also indicates that these bioactive substances effectively treat HL-60 and MCF-7 cell lines in vitro. Furthermore, the phytochemical components derived from the plant are successful in treating SMMC-7721 cells. Finally, the study confirms that Clausena emarginata also treats SW480 cells with notable efficacy.
Preparations
Clausena emarginata is prepared as a 90% ethanol extract to facilitate the study of its chemical constituents. This specific extraction process was applied to both the stems and the leaves of the plant. Through this method, researchers were able to isolate sixteen distinct compounds for further analysis. The use of a 90% ethanol solvent proved effective in retrieving various substances, including siamenol and murrastanine A. Ultimately, this preparation allowed for the successful evaluation of the extract's bioactive properties.
Parts used
Clausena emarginata serves as a significant source of diverse phytochemicals found specifically within its leaves and stems. Extensive research has utilized extracts from these plant parts to isolate a variety of chemical constituents, including numerous carbazole alkaloids. Through various purification methods, scientists have successfully identified several unique compounds from both the stems and the leaves. These isolated substances, such as clausemargine A, have demonstrated notable antiproliferative activities against multiple human cancer cell lines. Consequently, the chemical potential residing in the leaves and stems of this species continues to be a primary focus for pharmacological study.