Devil'S Ivy (Cissus Quadrangularis)

Information Reliability Score: 5/10

This score reflects the overall reliability of the information presented in this article. It is based on the quality of scientific evidence, accuracy of sources, and the transparency of references related to Cissus quadrangularis.

herbal Devil'S Ivy

Devil's Ivy, scientifically known as Cissus quadrangularis, is a medicinal herb native to tropical regions of Africa and Asia, prized for its adaptogenic properties and diverse therapeutic applications.

This climbing plant is rich in nutrients such as calcium, magnesium, and antioxidants, offering primary benefits like bone strengthening, anti-inflammatory support, and improved metabolic function. Traditionally used in Ayurvedic and African medicine, it has been valued for treating fractures, arthritis, and digestive disorders, while also being incorporated into cultural rituals for its perceived healing powers. In modern wellness practices, Devil's Ivy is increasingly used in herbal supplements and functional foods to support joint health, stress resilience, and overall vitality.

Its unique feature is the presence of a rare compound called cissus quadrangularis extract, which has shown potential in promoting tissue repair and enhancing physical performance, making it a standout in the world of natural medicine.

Table of Contents

Scientific and Botanical Profile

Devil'S Ivy, with botanical name Cissus quadrangularis, is a climbing plant belonging to the family Vitaceae, commonly known as the grapevine family.

Native to Africa, Madagascar, and parts of South Asia, including regions like Uttarakhand in India, this versatile species is also referred to as Devil'S Backbone, Indian Rubber Plant, and Creeping Fig, among many other common names. Morphologically, it features slender, woody stems with four-sided, glossy leaves that are oval-shaped, giving rise to its common name Ovalleaf Devil'S Ivy, while its small, yellowish-green flowers are followed by edible, berry-like fruits.

The plant is also known by various other names such as Cissus Ivy, Mandarin Vine, and even Creeping Woodsorrel, reflecting its widespread distribution and diverse cultural significance across different regions.

History and Cultural Relevance

Devil's Ivy, scientifically known as Cissus quadrangularis, was used extensively in traditional medicine across various cultures in Africa, the Middle East, and South Asia for centuries.

Indigenous communities in regions such as Nigeria, Kenya, and India have long recognized its healing properties, incorporating it into herbal remedies for ailments ranging from bone fractures to digestive issues. In many African cultures, the plant holds deep spiritual significance, often being used in rituals to promote fertility, prosperity, and protection against malevolent forces. Traditional healers, or sangomas in Southern Africa, have historically relied on Devil's Ivy to prepare poultices and decoctions for treating wounds, inflammation, and even diabetes, with some of these remedies still being practiced today.

Its enduring presence in both medicinal and cultural practices underscores its vital role in preserving ancestral knowledge and healing traditions.

Chemical Composition and Nutritional Profile

Devil's Ivy, or Cissus quadrangularis, contains a diverse array of bioactive compounds, including alkaloids, flavonoids, essential oils, and terpenes, which contribute to its medicinal properties.

It is also rich in nutrients such as vitamins C and E, potassium, calcium, and magnesium, along with antioxidants like polyphenols and tannins that support overall health. The alkaloids in Devil's Ivy may interact with neurotransmitter systems, while flavonoids and terpenes exhibit anti-inflammatory and antioxidant effects. These compounds work synergistically to enhance bone health, reduce oxidative stress, and support immune function by modulating cellular signaling pathways.

Overall, Devil's Ivy's unique chemical composition and nutritional profile make it a valuable plant in traditional and modern health applications.

Medicinal Properties and Health Benefits

Cissus quadrangularis has been widely recognized for its potent medicinal properties and diverse health benefits, particularly in supporting bone health, joint function, and overall musculoskeletal wellness.

It is rich in calcium, collagen, and various phytochemicals that promote bone regeneration and reduce inflammation, making it beneficial for the skeletal system and connective tissues. Compared to similar herbs like ashwagandha or turmeric, cissus quadrangularis stands out for its unique ability to enhance bone density and accelerate fracture healing, with studies suggesting it may be more effective than conventional calcium supplements in promoting bone growth. Its anti-inflammatory and antioxidant properties also support the immune system and may aid in managing conditions like arthritis and osteoporosis.

Overall, cissus quadrangularis offers a natural, potent alternative for those seeking to improve bone health and joint mobility, with advantages that set it apart from other traditional herbs.

Discover the 10 best health benefits of Devil'S Ivy.

Forms, Preparation and Usage

Cissus quadrangularis has been traditionally used in Ayurvedic medicine for its healing properties, and it is available in various forms such as fresh leaves, dried tincture, powder, essential oil, and capsules.

To prepare it, it can be made into a tea by steeping dried leaves in hot water, or a decoction can be made by boiling the leaves for a longer period. It can also be used in an infusion or applied topically as a poultice for skin conditions. The recommended dosage for adults is typically 1-3 grams of the powder or 1-2 capsules per day, while for children, it is advisable to consult a healthcare professional before use.

Due to the lack of extensive research, it is recommended to use it sparingly and for short durations, typically no longer than a few weeks, unless under medical supervision.

Safety, Side Effects and Contraindications

Cissus quadrangularis can be considered relatively safe when used in recommended doses for short-term periods, but it may cause side effects such as gastrointestinal discomfort, nausea, or allergic reactions in some individuals.

It is generally not known to interact with most medications, but caution is advised when combined with anticoagulants or antiplatelet drugs due to potential effects on blood clotting. Special populations, including pregnant or breastfeeding women, should avoid cissus quadrangularis due to insufficient research on its safety during these periods. Individuals with chronic illnesses, such as diabetes or hypertension, should consult a healthcare provider before using this herb, as it may influence blood sugar or blood pressure levels.

To ensure safe use, it is recommended to follow recommended dosages, consult with a healthcare professional, and discontinue use if any adverse effects occur.

Growing, Harvesting and Storage

Cissus quadrangularis grows best in well-drained sandy or loamy soil with a pH between 5.

5 and 7. 5, in full sun to partial shade, and with moderate watering to keep the soil slightly moist but not waterlogged. Regular pruning and fertilization with a balanced fertilizer during the growing season promote vigorous growth and enhance the plant's medicinal properties. The best time to harvest the stems is during the dry season, when the leaves and stems are mature and have accumulated high concentrations of active compounds; careful cutting with a sharp tool ensures minimal damage to the plant. After harvesting, the stems should be dried in a shaded, well-ventilated area to preserve their potency, then stored in airtight containers in a cool, dry place or refrigerated to maintain their medicinal efficacy.

Proper care and timely harvesting are essential to ensure the quality and therapeutic value of Cissus quadrangularis.