Cirsium maackii
Cirsium maackii · Accepted scientific name
Scientific literature: Very Sparse (1 studies) · ★☆☆☆☆
Cirsium maackii is a versatile botanical species whose therapeutic potential is derived from its flowers, leaves, and roots. Scientific investigations into its various extracts and ethyl acetate (EtOAc) fractions have revealed a significant capacity for neuroprotective activities. Central to these biological effects is the presence of the specific chemical compound cirsimaritin. Research indicates that preparations of this plant can address diverse medical conditions, including depression and the regulation of angiogenesis. Furthermore, studies suggest its efficacy in managing breast cancer and providing antidiabetic benefits.
- Synonyms
- Cirsium Litorale Var. Ussuriense · Cirsium Asperum · 12 more
- Common names
- Not available
- Family
- Asteraceae
- Distribution
- Not available
- Plant Parts
- Flower · Leaf
Classification
Common Names
Cirsium maackii is a distinctive plant recognized by various regional monikers across different languages. In certain areas, it is frequently referred to by its common name, Бодяк Маака. Moving to a different linguistic context, the species is also known as シロバナカラノアザミ. These diverse names highlight the plant's wide geographical distribution and cultural presence. Understanding these various identities helps enthusiasts identify the thistle regardless of their local terminology.
Sources: Catalogue of Life (COL)
Synonyms
Cirsium maackii is a plant recognized by several different botanical names within scientific literature. It is frequently identified by the synonym Cirsium asperum in various taxonomic contexts. The species also shares close nomenclature with Cirsium japonicum subsp. maackii and the variety Cirsium japonicum var. maackii. Furthermore, its classification includes Cirsium japonicum var. amurense and the distinct Cirsium japonicum var. spinossimum. Understanding these overlapping synonyms is essential for accurate identification and botanical study.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Cirsium maackii is a fascinating specimen that belongs to the expansive kingdom Plantae. Within this biological realm, the plant is classified under the class Equisetopsida. It further resides in the order Asterales, showcasing its evolutionary connections to a diverse group of flowering plants. As a member of the genus Cirsium, it displays the characteristic traits typical of its immediate relatives. Finally, it is nested within the family Asteraceae, placing it among the widely recognized composites.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Asterales |
| Family | Asteraceae |
| Genus | Cirsium |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Cirsium maackii is a resilient species primarily distributed throughout the temperate regions of Asia. Its presence is widely documented across various parts of China, including the Inner Mongolia and Manchuria regions. The plant also establishes itself throughout Eastern Asia, with significant populations found in Korea. Further north, its range extends into the Russian Far East, specifically within the Khabarovsk and Primorye territories. This broad geographic spread highlights the adaptability of the species to diverse temperate environments.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Cirsium maackii is a self-supporting herb that stands firmly within its natural habitat. This plant typically reaches a maximum height of 1.5 meters as it matures. Depending on environmental conditions, its stature can vary significantly throughout its life cycle. Individual specimens may grow as small as 0.4 meters, while many others maintain a more substantial presence. Frequently, the plant settles into a more consistent height range starting at approximately 0.95 meters.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Cirsium maackii, specifically the variety Cirsium japonicum var. maackii, has demonstrated significant neuroprotective activity against neurotoxicity induced by amyloid beta. Research using SH-SY5Y cells shows that extracts from this plant can effectively increase cell viability when subjected to amyloid beta-induced stress. The plant works by preventing the accumulation of reactive oxygen species and suppressing the production of inflammatory cytokines. Additionally, it helps regulate apoptotic signaling pathways to protect neurons from programmed cell death. Ultimately, the identification of pectolinarin as a key bioactive compound highlights the potential of this plant as a novel medicinal source for brain health.
Compounds
Cirsium maackii, also known as Cirsium japonicum var. maackii, is a medicinal herb rich in bioactive compounds with significant therapeutic potential. Research indicates that this plant contains the polyphenol cirsimaritin, which has demonstrated the ability to inhibit angiogenesis and serve as a potential anti-metastatic agent against breast cancer. Furthermore, the plant is a source of pectolinarin, a key compound identified within its ethyl acetate fraction. This specific component has shown remarkable neuroprotective effects by attenuating neurotoxicity induced by amyloid beta. Together, these chemical constituents highlight the diverse medicinal value of Cirsium maackii in addressing both oncological and neurological health challenges.
Conditions
Cirsium maackii demonstrates significant neuroprotective capabilities by treating amyloid beta25-35-induced neurotoxicity in SH-SY5Y cells. This plant effectively treats the production of inflammatory cytokines, such as interleukin-1β, that are mediated by Aβ25-35. Additionally, it treats the accumulation of reactive oxygen species to help protect neuronal health. Regarding cancer research, its components can treat angiogenesis by inhibiting tube formation and downregulating specific signaling pathways. Finally, the species is recognized for its medicinal value in providing antidiabetic effects.
Preparations
Cirsium maackii is prepared as various extracts and fractions to investigate its medicinal properties. Specifically, the plant is prepared as extract/fractions to test its ability to attenuate neuronal toxicity caused by amyloid beta. Researchers also utilized Cirsium maackii prepared as an ethyl acetate (EtOAc) fraction, which demonstrated superior neuroprotective bioactivities compared to other fractions. Additionally, the plant is prepared as an extract, such as the ethanol extract, to evaluate its potential as an anti-metastatic agent against breast cancer. These different preparation methods allow for the identification of specific bioactive compounds like pectolinarin and cirsimaritin.
Parts used
Cirsium maackii exhibits a complex biological structure that includes specialized plant parts such as the flower, leaf, and root. Research into related species within the Cirsium genus highlights how different tissues play distinct roles in metabolic processes. For instance, differential gene expression can vary significantly between the flowers and the roots of these medicinal plants. The leaves also serve as a critical component in the overall physiological and genetic profile of the organism. Understanding these specific relationships between the plant and its various parts is essential for studying its medicinal properties.