Chelidonium Majus Uses, Benefits, And Remedies

Chelidonium majus, commonly known as greater celandine, is a flowering plant native to Europe and parts of Asia, characterized by its yellow flowers and toxic yellow latex.
This herb has been traditionally used for its detoxifying properties and is believed to support liver function and skin health.
The bioactive constituents include alkaloids such as chelidonine and sanguinarine, which contribute to its anti-inflammatory and analgesic effects.
Herbal preparations such as infusions, tinctures, and topical salves can be made from its leaves and roots, though caution is advised due to its toxicity.
This page analize the most important medicinal aspects of Chelidonium majus.
- Health Benefits
- Bioactive Constituents
- Medicinal Parts
- Herbal Preparations
- Side Effects of chelidonium majus
Health Benefits
Chelidonium majus reduces inflammation by containing alkaloids that inhibit pro-inflammatory pathways in the body, which can help alleviate symptoms associated with chronic inflammatory conditions.
This herb is also known to relieve joint pain, making it a potential natural remedy for individuals suffering from arthritis or other inflammatory joint disorders. Its ability to boost the immune system comes from its rich content of antioxidants and bioactive compounds that enhance the body's defense mechanisms against infections and diseases. Additionally, Chelidonium majus has been traditionally used to reduce high fever, possibly due to its antipyretic properties that help regulate body temperature.
While these health benefits are promising, it is important to consult a healthcare professional before using this herb, as it may interact with certain medications or have side effects in some individuals.
The 7 best health benefits of Chelidonium majus are shown in the image below.

The list below give a brief description of the 7 best health benefits of Chelidonium majus.
- Reduces Inflammation: Chelidonium majus contains compounds that may help reduce inflammation in the body, potentially alleviating symptoms associated with inflammatory conditions.
- Relieves Joint Pain: The herb is traditionally used to help relieve joint pain, possibly due to its anti-inflammatory and analgesic properties.
- Boosts Immune System: Chelidonium majus may support the immune system by enhancing the body's natural defenses against infections and diseases.
- Reduces Fever High: It has been used historically to help reduce high fever, likely due to its antipyretic properties that help lower body temperature.
- Reduces Muscle Spasm: The herb may help reduce muscle spasms by relaxing muscle tissues and alleviating tension.
- Kills Bacteria Cell: Chelidonium majus contains antimicrobial compounds that may help kill harmful bacteria, supporting overall health.
- Eases Digestive Issue: It is traditionally used to ease digestive issues such as indigestion and bloating, possibly by stimulating digestive processes.
Bioactive Constituents
Chelidonium majus alkaloids, such as chelidonine, sanguinarine, and berberine, are among the most significant medicinal constituents of the plant, known for their potent pharmacological effects.
These alkaloids exhibit strong analgesic, anti-inflammatory, and antimicrobial properties, making them valuable in traditional and modern medicine. Chelidonine, in particular, has been studied for its ability to act as a central nervous system depressant and for its potential in pain management. Sanguinarine is noted for its ability to inhibit microbial growth and has been used in the treatment of infections.
Berberine, although more commonly associated with other plants like Hydrastis canadensis, is also present in Chelidonium majus and contributes to its antimicrobial and anti-inflammatory activities. These alkaloids, along with other compounds such as sterols, flavonoids, and glycosides, work synergistically to enhance the therapeutic potential of Chelidonium majus. However, due to their toxic nature, the use of this herb requires careful regulation and professional guidance to avoid adverse effects.
Overall, the alkaloids of Chelidonium majus play a crucial role in its medicinal profile, offering both therapeutic benefits and potential risks.
The 9 best bioactive constituents of Chelidonium majus are shown in the image below.

The list below give a brief description of the 7 best bioactive constituents of Chelidonium majus.
- Alkaloids: Alkaloids are nitrogen-containing organic compounds that have significant physiological effects on humans and animals, often used in medicinal applications for their therapeutic properties.
- Sterols: Sterols are a class of organic compounds that include cholesterol and other similar molecules, often involved in cell membrane structure and function, and may have anti-inflammatory properties.
- Flavonoids: Flavonoids are a diverse group of plant secondary metabolites known for their antioxidant properties and potential health benefits, including anti-inflammatory and anti-cancer effects.
- Glycosides: Glycosides are compounds composed of a sugar molecule bonded to a non-sugar moiety, often having medicinal properties such as cardiac or antimicrobial effects.
- Minerals: Minerals are inorganic elements essential for various physiological functions in the body, including bone health, enzyme function, and metabolic processes.
- Terpenoids: Terpenoids are a large and diverse class of organic compounds derived from isoprene units, often having aromatic and medicinal properties such as anti-inflammatory and antiviral effects.
- Carotenoids: Carotenoids are pigments found in plants that act as antioxidants, supporting immune function and contributing to the prevention of chronic diseases.
- Phenolic Acids: Phenolic acids are organic compounds with antioxidant properties that help neutralize free radicals, reduce inflammation, and support overall health.
- Fatty Acids: Fatty acids are essential components of cell membranes and play a key role in energy storage, signaling, and the regulation of various physiological processes.
Medicinal Parts
Chelidonium majus leaf contains various bioactive compounds such as alkaloids, flavonoids, and terpenoids, which contribute to its medicinal properties.
The leaves are traditionally used for their anti-inflammatory and analgesic effects, making them useful in treating conditions like rheumatism and skin irritations. However, due to the presence of toxic alkaloids such as chelidonine and sanguinarine, the leaves must be used with caution and under professional supervision.
In some traditional herbal practices, the leaves are also employed to stimulate digestion and treat respiratory ailments. While the leaves are a primary source of medicinal compounds, the root and fruit of Chelidonium majus also contain valuable components. The root is known for its potential antispasmodic and antidiarrheal properties, while the fruit contains alkaloids that may have applications in treating parasitic infections.
Overall, all parts of Chelidonium majus have been historically valued in herbal medicine, though their use requires careful handling due to the plant's inherent toxicity.
The 3 best medicinal parts of Chelidonium majus are shown in the image below.

The list below give a brief description of the 3 best medicinal parts of Chelidonium majus.
Herbal Preparations
Chelidonium majus tinctures are commonly used in herbal medicine for their purported ability to support liver function and detoxification processes.
These tinctures are typically made by soaking the dried plant material in alcohol, which helps extract the active compounds such as alkaloids like chelidonine and sanguinarine. They are often recommended for digestive support and as a remedy for skin conditions, though they should be used with caution due to their potential toxicity.
Chelidonium majus decoctions involve boiling the herb in water to create a concentrated herbal tea, which is believed to aid in clearing liver congestion and promoting overall metabolic health. Capsules provide a more convenient and standardized form of the herb, allowing for consistent dosing and easier integration into daily routines. In addition to these forms, chelidonium majus oils are sometimes used topically for their anti-inflammatory properties, though they should be diluted before application to avoid skin irritation.
Each preparation method offers unique benefits and considerations, making it essential to consult a qualified herbalist or healthcare provider before use.
The 4 best herbal preparations of Chelidonium majus are shown in the image below.

The list below give a brief description of the 4 best herbal preparations of Chelidonium majus.
- Tinctures: Chelidonium majus tinctures are used to support digestive health and may help with liver function and skin conditions due to the herb's alkaloid content.
- Decoctions: Chelidonium majus decoctions are traditionally used to aid in detoxification, alleviate skin ailments, and support the treatment of certain inflammatory conditions.
- Capsules: Chelidonium majus capsules provide a convenient form of the herb for supporting liver function, digestive health, and skin-related issues when taken as directed.
- Oils: Chelidonium majus oils are often used topically to address skin conditions and may be applied to support localized inflammation and healing of the skin.
Side Effects of chelidonium majus
Chelidonium majus causes skin irritation, which can manifest as redness, itching, or a burning sensation upon contact with the plant's sap or when ingested.
This herb is known to induce vomiting and lead to nausea, often as a result of its toxic alkaloids, which can irritate the gastrointestinal tract. Prolonged or excessive use of Chelidonium majus may cause liver damage, as it has been associated with hepatotoxic effects, particularly when consumed in high doses or over extended periods.
Additionally, the herb can cause eye irritation, including redness, tearing, and discomfort, if the sap comes into contact with the eyes. It may also result in a rash, drowsiness, and other systemic effects, making it a potentially dangerous plant for both topical and internal use.
Due to these significant health risks, Chelidonium majus should be handled with caution and is generally not recommended for medicinal use without professional supervision.
The 7 most common side effects of Chelidonium majus are shown in the image below.

The list below give a brief description of the 7 most common side effects of Chelidonium majus.
- Causes Skin Irritation: Chelidonium majus can cause skin irritation due to the presence of alkaloids and other irritant compounds that may affect the skin's surface.
- Induces Vomiting: The herb contains compounds that can stimulate the vomiting reflex, making it potentially toxic if ingested in large amounts.
- Leads To Nausea: Chelidonium majus may cause nausea due to its effects on the gastrointestinal system and its alkaloid content.
- May Cause Liver Damage: Long-term or excessive use of Chelidonium majus may lead to liver damage due to its potential hepatotoxic properties.
- Causes Eye Irritation: Contact with the eyes can result in irritation due to the presence of irritant compounds in the herb.
- Results In Rash: The herb can cause a rash due to allergic reactions or irritation from its alkaloids and other chemical compounds.
- Results In Drowsiness: Chelidonium majus may cause drowsiness due to its potential sedative effects on the central nervous system.