Greater celandine
Chelidonium majus · Accepted scientific name
Scientific literature: Very Extensive (545 studies) · ★★★★★
Greater celandine, scientifically known as Chelidonium majus, is a perennial herbaceous plant renowned for its bright yellow, latex-rich sap. Traditionally used in herbal medicine to treat skin conditions and liver ailments, it contains potent alkaloids. However, its high toxicity requires cautious application and expert guidance during medicinal use.
- Family
- Papaveraceae
- Native range
- Europe
- Parts used
- Root
- Common names
- Celandine · Greater Celandine · 5 more
- Scientific synonyms
- Not available
Names and Synonyms
Common Names
- celandine
- greater celandine
- rock poppy
- swallowwort
- great celandine
- nipplewort
- Swallow-wort
Scientific Names
Accepted name
Chelidonium majusRegional and Traditional Names
Spanish:
- Pedigueña
- Verrugera
- Chiledonia
- Celiduena
- Ceredueña
- Ceridueña
- Hierba golondrinera
- Ciledonia
- Cerigueña
- Cilidueña
- Pediguena
- Cirigueña
- Cerdueña
- Hierba de las golondrinas
- Hirundinaria
- Ceredonia
- dilidonia
- flor de la golondrina
- golondrinera
- gran luz
- cedueña
- celdueña
- celedonia
- celedonio
- celidoña
- celidonia
- celidonia mayor
- celidueña
- celidueña fina
- cerdoña
- ceridoña
- ceridonia
- cerigüeña
- ceruda
- cevuda
- cilidonia
- cirgüeña
- ciridueña
- cirigüeña
- cirigüeya
- cirirueña
- pedigüeña
- piohuelo
- planta del yodo
- quitaverrugas
- selidonia
- verruguera
- yerba de las golondrinas
- yerba del pordiosero
- yerba verruguera
- yeteira
- hierba de la golondrina
- hierba de las verrugas
- hierba del iodo
- hierba verruguera
- celidonia mayor
German:
- Schöllkraut
- Schellkraut
- grande chélidoine
- Schöllkraut
- Gewöhnliches Schöllkraut
- Schoellkraut
- Warzenkraut
French:
- Verrucaire
- Grande chélidoine
- Quélidoine
- Herbe aux verrues
- Chélidoine
- Chelidoine
- Herbe à verrues
- Kélidoine
- chélidoine
- chélidoine herbe-aux-verrues
- chélidoine majeure
- grande chélidoine
- grande éclaire
- herbe aux verrues
- éclaire
- Chelidoine
- Herbe-aux-verrues
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and class Equisetopsida. Within the subclass Magnoliidae, it is further organized under the order Ranunculales and the family Papaveraceae. Finally, its specific taxonomic identity is defined by the genus Chelidonium.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Ranunculales |
| Family | Papaveraceae |
| Genus | Chelidonium |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a specific geographical distribution across several regions in Northern Europe. It can be found growing within the borders of Denmark and Finland. Furthermore, its presence extends to the islands of Great Britain and Ireland. The species is also documented as occurring in Norway. Together, these locations define its northern European habitat.
| Region | Area |
|---|---|
| Northern Europe | Denmark |
| Northern Europe | Finland |
| Northern Europe | Great Britain |
| Northern Europe | Ireland |
| Northern Europe | Norway |
| Northern Europe | Sweden |
| Middle Europe | Austria |
| Middle Europe | Belgium |
| Middle Europe | Czechia-Slovakia |
| Middle Europe | Germany |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Ecology
The ecology of Chelidonium majus is characterized by its broad adaptability across varying altitudinal gradients, spanning from sea level up to a maximum elevation of 2200 m AMSL. It is most frequently observed in lowland habitats, though it maintains a significant presence throughout middle elevations, with a mean elevational range centered around 1350 m AMSL. This wide distribution allows the species to occupy diverse ecological niches across a diverse range of vertical landscapes.
- Elevational range max:
- 2200 m AMSL
- Elevational range mean:
- 1350 m AMSL
- Elevational range min:
- 0 m AMSL
- Habitat :
- Lowland
Life history
The life history of Chelidonium majus is characterized by its status as a perennial plant, allowing it to persist through multiple growing seasons. It functions as a hemicryptophyte, a life form where the perennating buds are located at the soil surface, protected by leaf litter or soil cover during unfavorable periods. Furthermore, the species exhibits a deciduous nature, shedding its foliage annually as it transitions through its seasonal cycles.
- Deciduousness :
- deciduous
- Life form :
- hemicryptophyte
- Lifecycle :
- perennial
Morphology
The morphology of Chelidonium majus is characterized by a growth form classified as both a herb and a forb. It is a terrestrial, non-woody plant that functions as an independent organism rather than a parasite or epiphyte. The plant typically exhibits an erect shoot orientation and is self-supporting, lacking any climbing or vine-like tendencies. In terms of stature, it maintains a relatively low profile, with a plant height that ranges from a minimum of 0.3 m to a maximum of 1 m, resulting in a mean height of approximately 0.5057 m.
- Aquatic :
- terrestrial
- Climber :
- self-supporting
- Epiphyte :
- terrestrial
- Growth form :
- herb
- Growth form :
- forb
- Parasite :
- independent
- Plant height max:
- 1 m
- Plant height mean:
- 0.505666666666667 m
- Plant height min:
- 0.3 m
- Shoot orientation :
- erect
- Woodiness :
- non-woody
Physiology
The physiology of Chelidonium majus is characterized by a C3 photosynthetic pathway and a non-carnivorous nutritional strategy. Its foliage exhibits significant morphological diversity, featuring a pinnate leaf form with a mean leaf size of 92.26 cm². The leaf dimensions vary considerably, with a mean leaf length of 5 cm (ranging from a minimum of 2 cm to a maximum of 20 cm) and a mean leaf width of 8 cm (ranging from a minimum of 1 cm to a maximum of 10 cm). Furthermore, the plant maintains a mean Specific Leaf Area (SLA) of 426.08 cm²/g, reflecting its leaf mass per area and its physiological adaptation to its specific ecological niche.
- Carnivory :
- non-carnivorous
- Leaf form :
- pinnate
- Leaf length max:
- 20 cm
- Leaf length mean:
- 5 cm
- Leaf length min:
- 2 cm
- Leaf size mean:
- 92.26 cm²
- Leaf width max:
- 10 cm
- Leaf width mean:
- 8 cm
- Leaf width min:
- 1 cm
- Photosynthetic pathway :
- C3
- Specific Leaf Area (SLA) mean:
- 426.08 cm²/g
Reproduction
The reproduction of Chelidonium majus is characterized by a sexual process through bisexual flowers, with asexual reproduction being absent. The flowering period typically commences in May and concludes in July, featuring yellow flowers that range in length from 0.7 cm to 1.2 cm. These flowers utilize a biotic pollination syndrome, primarily relying on insects, specifically bees, to facilitate fertilization; notably, self-fertilization is present. Following successful pollination, the plant develops dry fruit in the form of capsules. These capsules vary in size, with an average length of 3.5 cm (ranging from 2 cm to 5 cm) and an average width of 0.25 cm (ranging from 0.2 cm to 0.3 cm). Each fruit is prolific, containing between 101 and 1000 seeds. The seeds themselves are quite small, with a mean mass of approximately 0.000732889 g (ranging from 0.00051 g to 0.00091 g), a length between 1 mm and 1.5 mm, and a consistent volume of 0.47 mm³. Seed dispersal follows a zoochorous syndrome, specifically exhibiting myrmecochorous traits, indicating that ants play a role in the dispersal of the seeds.
- Dispersal syndrome :
- zoochorous
- Dispersal syndrome :
- myrmecochorous
- Flower colour :
- yellow
- Flower length max:
- 1.2 cm
- Flower length min:
- 0.7 cm
- Flowering time :
- May
- Flowering time :
- Jul
- Fruit dryness :
- dry
- Fruit length max:
- 5 cm
- Fruit length mean:
- 3.5 cm
- Fruit length min:
- 2 cm
- Fruit type :
- capsule
- Fruit width max:
- 0.3 cm
- Fruit width mean:
- 0.25 cm
- Fruit width min:
- 0.2 cm
- Pollination syndrome :
- insect
- Pollination syndrome :
- bee
- Pollination syndrome :
- biotic
- Reproduction asexual :
- absent
- Reproduction sexual :
- bisexual
- Seed length max:
- 1.5 mm
- Seed length min:
- 1 mm
- Seed mass max:
- 0.00091 g
- Seed mass mean:
- 0.000732889 g
- Seed mass min:
- 0.00051 g
- Seed volume max:
- 0.47 mm³
- Seeds_per_fruit :
- 101-1000
- Self fertilization :
- present
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Chelidonium majus has 1 reported plant parts identified across 1 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include root.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Root | 1 supporting sources | ★☆☆☆☆ |
Root
- Toxins
Chemicals
Chelidonium majus has 81 reported phytochemicals identified across 1 scientific publications and several other databases. The most consistently reported chemicals include SANGUINARINE, CHELIDONINE, chelerythrine, Coptisine, protopine.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| SANGUINARINE | 15 supporting sources | ★★★★★ |
| CHELIDONINE | 13 supporting sources | ★★★★★ |
| chelerythrine | 12 supporting sources | ★★★★★ |
| Coptisine | 8 supporting sources | ★★★★☆ |
| protopine | 7 supporting sources | ★★★★☆ |
| berberine | 6 supporting sources | ★★★☆☆ |
| Allocryptopine | 4 supporting sources | ★★☆☆☆ |
| Dihydrosanguinarine | 3 supporting sources | ★★☆☆☆ |
| Stylopine | 3 supporting sources | ★★☆☆☆ |
| 8-Hydroxydihydrochelerythrine | 2 supporting sources | ★☆☆☆☆ |
SANGUINARINE
- Dr. Duke
- Planta medica
- Journal of ethnopharmacology
- Molecules (Basel, Switzerland)
- Toxins
View 10 additional sources
- Talanta
- PloS one
- Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Tsitologiia
- Frontiers in pharmacology
- Journal of chromatography. A
- Journal of mass spectrometry : JMS
- Oxidative medicine and cellular longevity
- Neurochemistry international
CHELIDONINE
- Dr. Duke
- Planta medica
- Molecules (Basel, Switzerland)
- Journal of biochemical and molecular toxicology
- Georgian medical news
View 8 additional sources
- Cancer letters
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Tsitologiia
- Frontiers in pharmacology
- Journal of chromatography. A
- Toxins
- Journal of mass spectrometry : JMS
- Oxidative medicine and cellular longevity
chelerythrine
- Dr. Duke
- Planta medica
- Journal of ethnopharmacology
- Molecules (Basel, Switzerland)
- Talanta
View 7 additional sources
- Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Frontiers in pharmacology
- Journal of chromatography. A
- Toxins
- Journal of mass spectrometry : JMS
- Neurochemistry international
Coptisine
- Dr. Duke
- Molecules (Basel, Switzerland)
- Phytochemistry
- Planta medica
- Phytomedicine : international journal of phytotherapy and phytopharmacology
View 3 additional sources
- Frontiers in pharmacology
- Journal of chromatography. A
- Journal of mass spectrometry : JMS
protopine
- Dr. Duke
- Molecules (Basel, Switzerland)
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Planta medica
- Journal of chromatography. A
View 2 additional sources
- Journal of mass spectrometry : JMS
- Oxidative medicine and cellular longevity
berberine
- Dr. Duke
- Molecules (Basel, Switzerland)
- Journal of separation science
- Frontiers in pharmacology
- Journal of chromatography. A
View 1 additional sources
- Neurochemistry international
Allocryptopine
- Dr. Duke
- Molecules (Basel, Switzerland)
- Planta medica
- Journal of chromatography. A
Dihydrosanguinarine
- Dr. Duke
- Journal of ethnopharmacology
- Georgian medical news
Stylopine
- Dr. Duke
- Planta medica
- Journal of chromatography. A
8-Hydroxydihydrochelerythrine
- Journal of ethnopharmacology
- Molecules (Basel, Switzerland)
Activities
Chelidonium majus has 254 reported activities identified across 1 scientific publications and several other databases. The most consistently reported activities include Antimicrobial, Anticancer, Antioxidant, Analgesic, Antiviral.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Antimicrobial | 5 supporting sources | ★★★☆☆ |
| Anticancer | 4 supporting sources | ★★☆☆☆ |
| Antioxidant | 4 supporting sources | ★★☆☆☆ |
| Analgesic | 3 supporting sources | ★★☆☆☆ |
| Antiviral | 3 supporting sources | ★★☆☆☆ |
| Antibacterial | 2 supporting sources | ★☆☆☆☆ |
| Antineoplastic | 2 supporting sources | ★☆☆☆☆ |
| Antispasmodic | 2 supporting sources | ★☆☆☆☆ |
| Antitussive | 2 supporting sources | ★☆☆☆☆ |
| Cholagogue | 2 supporting sources | ★☆☆☆☆ |
Antimicrobial
- Plants (Basel, Switzerland)
- Pharmaceutics
- European review for medical and pharmacological sciences
- Materials (Basel, Switzerland)
- Frontiers in pharmacology
Anticancer
- Dr. Duke
- Plants (Basel, Switzerland)
- Pharmaceutics
- Frontiers in pharmacology
Antioxidant
- Dr. Duke
- Plants (Basel, Switzerland)
- Pharmaceutics
- Food technology and biotechnology
Analgesic
- Dr. Duke
- Journal of biochemical and molecular toxicology
- European review for medical and pharmacological sciences
Antiviral
- Dr. Duke
- Plants (Basel, Switzerland)
- Frontiers in pharmacology
Antibacterial
- Dr. Duke
- Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Antineoplastic
- Dr. Duke
- European review for medical and pharmacological sciences
Antispasmodic
- Dr. Duke
- Planta medica
Antitussive
- Dr. Duke
- European review for medical and pharmacological sciences
Cholagogue
- Dr. Duke
- Frontiers in pharmacology
Conditions
Chelidonium majus has 44 reported investigations on conditions identified across 1 scientific publications and several other databases. The most consistently reported conditions include cancer, analgesic, irritable bowel syndrome, tumor, Bacillus subtilis.
| Condition | Supporting sources | Consensus |
|---|---|---|
| Cancer | 5 supporting sources | ★★★☆☆ |
| Analgesic | 3 supporting sources | ★★☆☆☆ |
| Irritable bowel syndrome | 2 supporting sources | ★☆☆☆☆ |
| Tumor | 2 supporting sources | ★☆☆☆☆ |
| Bacillus subtilis | 1 supporting sources | ★☆☆☆☆ |
| Cancer | 1 supporting sources | ★☆☆☆☆ |
| Endometriosis | 1 supporting sources | ★☆☆☆☆ |
| Fusarium | 1 supporting sources | ★☆☆☆☆ |
| Melanoma | 1 supporting sources | ★☆☆☆☆ |
| Antineoplastic | 1 supporting sources | ★☆☆☆☆ |
Cancer
- International journal of biological macromolecules
- Fitoterapia
- Frontiers in pharmacology
- Phytotherapy research : PTR
- Phytomedicine : international journal of phytotherapy and phytopharmacology
Analgesic
- Journal of biochemical and molecular toxicology
- European review for medical and pharmacological sciences
- Chemico-biological interactions
Irritable bowel syndrome
- Gastro hep advances
- Phytomedicine : international journal of phytotherapy and phytopharmacology
Tumor
- Journal of ethnopharmacology
- Journal of chromatography. A
Bacillus subtilis
- Journal of chromatography. A
Cancer
- Oxidative medicine and cellular longevity
Endometriosis
- Pharmaceutics
Fusarium
- Journal of ethnopharmacology
Melanoma
- Molecules (Basel, Switzerland)
Antineoplastic
- European review for medical and pharmacological sciences
Preparations
Chelidonium majus has 21 reported preparations identified across 1 scientific publications and several other databases. The most consistently reported preparations include extracts, C. majus extract, extract, 75% ethanol extract, Ethanolic extracts.
| Preparation | Supporting sources | Consensus |
|---|---|---|
| Extracts | 6 supporting sources | ★★★☆☆ |
| C. majus extract | 2 supporting sources | ★☆☆☆☆ |
| Extract | 2 supporting sources | ★☆☆☆☆ |
| 75% ethanol extract | 1 supporting sources | ★☆☆☆☆ |
| Ethanolic extracts | 1 supporting sources | ★☆☆☆☆ |
| H2 | 1 supporting sources | ★☆☆☆☆ |
| H3 | 1 supporting sources | ★☆☆☆☆ |
| Root extract | 1 supporting sources | ★☆☆☆☆ |
| Aerial parts | 1 supporting sources | ★☆☆☆☆ |
| Aerial parts extract | 1 supporting sources | ★☆☆☆☆ |
Extracts
- Molecules (Basel, Switzerland)
- Talanta
- Arzneimittel-Forschung
- Toxins
- Pathogens (Basel, Switzerland)
View 1 additional sources
- Neurochemistry international
C. majus extract
- Molecules (Basel, Switzerland)
- Planta medica
Extract
- Sangre
- Journal of ethnopharmacology
75% ethanol extract
- Fitoterapia
Ethanolic extracts
- Bioscience, biotechnology, and biochemistry
H2
- Parasites & vectors
H3
- Parasites & vectors
Root extract
- Toxins
Aerial parts
- Fitoterapia
Aerial parts extract
- Toxins