sneezweed

Centipeda minima · Accepted scientific name

Scientific literature: Moderate (106 studies) · ★★★☆☆

Sneezeweed, scientifically known as Centipeda minima, is a versatile medicinal herb widely utilized in traditional Asian medicine. Renowned for its potent anti-inflammatory, antioxidant, and antibacterial properties, this plant is frequently employed to treat skin conditions, respiratory issues, and various internal ailments, making it a significant subject in pharmacological research.

Family
Asteraceae
Native range
Europe
Parts used
Not available
Common names
Spreading Sneezeweed · Spreading-Sneezeweed
Scientific synonyms
Cotula Minima · Grangea Minima · 2 more

Names and Synonyms

Common Names

Scientific Names

Accepted name

Centipeda minima

Synonyms

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant, known scientifically as Centipeda minima, belongs to the kingdom Plantae and the phylum Streptophyta. It is classified under the class Equisetopsida and the subclass Magnoliidae within the order Asterales. Furthermore, it is a member of the family Asteraceae and is categorized under the genus Centipeda.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Asterales
Family Asteraceae
Genus Centipeda

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a diverse geographical distribution spanning several continents and climatic zones. In Middle Europe, its presence is documented in countries such as Belgium and Germany. Its range extends significantly into West Tropical Africa, specifically within the nation of Liberia. Furthermore, the species can be found in the Western Indian Ocean region. This oceanic distribution includes both the island of Mauritius and the large landmass of Madagascar.

Region Area
Middle Europe Belgium
Middle Europe Germany
West Tropical Africa Liberia
Western Indian Ocean Mauritius
Western Indian Ocean Madagascar
Western Indian Ocean Réunion
Russian Far East Amur
Russian Far East Khabarovsk
Russian Far East Primorye
China China South-Central

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Ecology

The ecology of Centipeda minima is characterized by its adaptability to various environments, typically found thriving in habitats such as crop fields, lakes, rivers, and along roadsides. This species occupies a specific altitudinal niche, maintaining an elevational range that spans from a minimum of 800 m AMSL to a maximum of 1400 m AMSL.

Elevational range max:
1400 m AMSL
Elevational range min:
800 m AMSL
Habitat :
crop fields, lakes, rivers, roadsides

Life history

The life history of Centipeda minima is characterized by an annual lifecycle, meaning the plant completes its entire developmental process—from germination to seed production—within a single growing season. In terms of its structural growth habit, it is classified as a therophyte, a life form defined by plants that survive the unfavorable season as ephemeral seeds, rapidly developing and flowering once conditions become suitable. This biological strategy allows the species to exploit transient environmental resources effectively before returning to a dormant seed state.

Life form :
therophyte
Lifecycle :
annual

Morphology

The morphology of Centipeda minima is characterized by its growth form as a non-woody herb, specifically classified as a forb. It is a terrestrial plant that functions as an independent organism, neither acting as a parasite nor as an epiphyte. In terms of its structural habit, the plant is self-supporting rather than being a liana or a vine. It maintains a relatively low stature, with a plant height ranging from 0 m to a maximum of 0.5 m, typically reaching a mean height of approximately 0.1 m.

Aquatic :
terrestrial
Climber :
self-supporting
Epiphyte :
terrestrial
Growth form :
herb
Growth form :
forb
Parasite :
independent
Plant height max:
0.5 m
Plant height mean:
0.1 m
Plant height min:
0 m
Woodiness :
non-woody

Physiology

The physiology of Centipeda minima is characterized by a C3 photosynthetic pathway, which dictates its metabolic processes and carbon fixation efficiency. The plant exhibits specific morphological dimensions in its foliage, with leaf lengths ranging from a minimum of 0.7 cm to a mean of 1.25 cm, reaching a maximum of 1.8 cm. Correspondingly, the leaf width varies from a minimum of 0.1 cm to a maximum of 0.4 cm. In terms of water storage and structural adaptation, the plant does not exhibit succulence, maintaining standard leaf tissue density. Furthermore, its nitrogen metabolism is characterized by the absence of nitrogen-fixing capabilities, meaning it relies on external soil nitrogen sources rather than symbiotic nitrogen fixation.

Leaf length max:
1.8 cm
Leaf length mean:
1.25 cm
Leaf length min:
0.7 cm
Leaf width max:
0.4 cm
Leaf width min:
0.1 cm
Nitrogen fixer :
no
Photosynthetic pathway :
C3
Succulence :
no

Reproduction

The reproduction of Centipeda minima is characterized by a specialized sexual process, as asexual reproduction is notably absent. The flowering period typically occurs between July and August, driven by biotic pollination syndromes, specifically involving insects. Following successful pollination, the plant produces small, indehiscent fruits classified as achenes. These fruits are quite minute, maintaining a consistent length of approximately 0.1 cm. Within these fruits, the seeds are uniform in size and mass, with a mean seed length of 1.4 mm and a mean seed mass of $2 \times 10^{-5}$ g (ranging from a minimum to a maximum of $2 \times 10^{-5}$ g). The dispersal of these seeds follows an anemochorous syndrome, meaning they are primarily dispersed by the wind to facilitate the colonization of new habitats.

Dehiscence :
indehiscent
Dispersal syndrome :
anemochorous
Flowering time :
Jul
Flowering time :
Aug
Fruit length max:
0.1 cm
Fruit type :
achene
Pollination syndrome :
insect
Pollination syndrome :
biotic
Reproduction asexual :
absent
Seed length mean:
1.4 mm
Seed mass mean:
2e-05 g

Sources: Global Inventory of Floras and Traits (GIFT)

Chemicals

Centipeda minima has 22 reported phytochemicals identified across 0 scientific publications and several other databases. The most consistently reported chemicals include BREVILIN A, 6-O-angeloylplenolin, Arnicolide C, Arnicolide D, Flavonoids.

Chemicals reported in Centipeda minima
Chemical Supporting sources Consensus
BREVILIN A 7 supporting sources ★★★★☆
6-O-angeloylplenolin 4 supporting sources ★★☆☆☆
Arnicolide C 4 supporting sources ★★☆☆☆
Arnicolide D 4 supporting sources ★★☆☆☆
Flavonoids 3 supporting sources ★★☆☆☆
CHLOROGENIC ACID 2 supporting sources ★☆☆☆☆
2beta-(Isobutyryloxy)florilenalin 1 supporting sources ★☆☆☆☆
Amide 1 supporting sources ★☆☆☆☆
Fatty acids 1 supporting sources ★☆☆☆☆
Glycosides 1 supporting sources ★☆☆☆☆

BREVILIN A

  1. Life sciences
  2. Plants (Basel, Switzerland)
  3. Frontiers in pharmacology
  4. Journal of pharmaceutical and biomedical analysis
  5. Molecules (Basel, Switzerland)
View 2 additional sources
  1. Phytomedicine : international journal of phytotherapy and phytopharmacology
  2. Journal of AOAC International

6-O-angeloylplenolin

  1. Chemical & pharmaceutical bulletin
  2. Phytochemistry
  3. Journal of ethnopharmacology
  4. Phytomedicine : international journal of phytotherapy and phytopharmacology

Arnicolide C

  1. Molecules (Basel, Switzerland)
  2. Journal of ethnopharmacology
  3. Journal of pharmaceutical and biomedical analysis
  4. Phytomedicine : international journal of phytotherapy and phytopharmacology

Arnicolide D

  1. Molecules (Basel, Switzerland)
  2. Journal of ethnopharmacology
  3. Phytomedicine : international journal of phytotherapy and phytopharmacology
  4. Journal of pharmaceutical and biomedical analysis

Flavonoids

  1. Journal of ethnopharmacology
  2. Chemical & pharmaceutical bulletin
  3. Mini reviews in medicinal chemistry

CHLOROGENIC ACID

  1. Phytomedicine : international journal of phytotherapy and phytopharmacology
  2. Journal of AOAC International

2beta-(Isobutyryloxy)florilenalin

  1. Molecules (Basel, Switzerland)

Amide

  1. Chemical & pharmaceutical bulletin

Fatty acids

  1. Mini reviews in medicinal chemistry

Glycosides

  1. Journal of pharmaceutical and biomedical analysis

Activities

Centipeda minima has 5 reported activities identified across 0 scientific publications and several other databases. The most consistently reported activities include Anticancer, Hepatoprotective, Antibacterial, Antineoplastic, Antioxidant.

Activities reported in Centipeda minima
Activity Supporting sources Consensus
Anticancer 2 supporting sources ★☆☆☆☆
Hepatoprotective 2 supporting sources ★☆☆☆☆
Antibacterial 1 supporting sources ★☆☆☆☆
Antineoplastic 1 supporting sources ★☆☆☆☆
Antioxidant 1 supporting sources ★☆☆☆☆

Anticancer

  1. Chinese medicine
  2. Phytomedicine : international journal of phytotherapy and phytopharmacology

Hepatoprotective

  1. Mini reviews in medicinal chemistry
  2. Fitoterapia

Antibacterial

  1. Phytochemistry

Antineoplastic

  1. Life sciences

Antioxidant

  1. Phytomedicine : international journal of phytotherapy and phytopharmacology

Conditions

Centipeda minima has 27 reported investigations on conditions identified across 0 scientific publications and several other databases. The most consistently reported conditions include rhinitis, sinusitis, breast cancer, headache, nasopharyngeal carcinoma.

Conditions investigated for Centipeda minima
Condition Supporting sources Consensus
Rhinitis 4 supporting sources ★★☆☆☆
Sinusitis 4 supporting sources ★★☆☆☆
Breast cancer 3 supporting sources ★★☆☆☆
Headache 3 supporting sources ★★☆☆☆
Nasopharyngeal carcinoma 3 supporting sources ★★☆☆☆
Asthma 2 supporting sources ★☆☆☆☆
Cough 2 supporting sources ★☆☆☆☆
Lung cancer 2 supporting sources ★☆☆☆☆
Melanoma 2 supporting sources ★☆☆☆☆
Non-small cell lung cancer 2 supporting sources ★☆☆☆☆

Rhinitis

  1. Journal of ethnopharmacology
  2. Chinese medicine
  3. Phytomedicine : international journal of phytotherapy and phytopharmacology
  4. Frontiers in oncology

Sinusitis

  1. Journal of ethnopharmacology
  2. Chinese medicine
  3. Phytomedicine : international journal of phytotherapy and phytopharmacology
  4. Frontiers in oncology

Breast cancer

  1. Life sciences
  2. Plants (Basel, Switzerland)
  3. Frontiers in oncology

Headache

  1. Journal of ethnopharmacology
  2. Chinese medicine
  3. Phytomedicine : international journal of phytotherapy and phytopharmacology

Nasopharyngeal carcinoma

  1. Journal of ethnopharmacology
  2. Chinese medicine
  3. Molecules (Basel, Switzerland)

Asthma

  1. Journal of ethnopharmacology
  2. Mini reviews in medicinal chemistry

Cough

  1. Journal of ethnopharmacology
  2. Chinese medicine

Lung cancer

  1. Life sciences
  2. Phytomedicine : international journal of phytotherapy and phytopharmacology

Melanoma

  1. Life sciences
  2. Phytomedicine : international journal of phytotherapy and phytopharmacology

Non-small cell lung cancer

  1. Journal of ethnopharmacology
  2. Phytomedicine : international journal of phytotherapy and phytopharmacology

Preparations

Centipeda minima has 14 reported preparations identified across 0 scientific publications and several other databases. The most consistently reported preparations include CMX, Centipeda minima extract (CME), Ether extract, aqueous extract, aqueous extracts.

Preparations reported for Centipeda minima
Preparation Supporting sources Consensus
Cmx 1 supporting sources ★☆☆☆☆
Centipeda minima extract (cme) 1 supporting sources ★☆☆☆☆
Ether extract 1 supporting sources ★☆☆☆☆
Aqueous extract 1 supporting sources ★☆☆☆☆
Aqueous extracts 1 supporting sources ★☆☆☆☆
Ethanol extract 1 supporting sources ★☆☆☆☆
Ethanol extract of c. minima 1 supporting sources ★☆☆☆☆
Ethanol extract of c. minima (ecm) 1 supporting sources ★☆☆☆☆
Ethanolic extract 1 supporting sources ★☆☆☆☆
Extract 1 supporting sources ★☆☆☆☆

Cmx

  1. Plants (Basel, Switzerland)

Centipeda minima extract (cme)

  1. Molecules (Basel, Switzerland)

Ether extract

  1. Chemical & pharmaceutical bulletin

Aqueous extract

  1. Chemical & pharmaceutical bulletin

Aqueous extracts

  1. Phytomedicine : international journal of phytotherapy and phytopharmacology

Ethanol extract

  1. Journal of pharmaceutical and biomedical analysis

Ethanol extract of c. minima

  1. Phytomedicine : international journal of phytotherapy and phytopharmacology

Ethanol extract of c. minima (ecm)

  1. Journal of ethnopharmacology

Ethanolic extract

  1. Journal of pharmaceutical and biomedical analysis

Extract

  1. Frontiers in pharmacology