Celastrus angulatus
Celastrus angulatus · Accepted scientific name
Scientific literature: Very Sparse (1 studies) · ★☆☆☆☆
Celastrus angulatus is a botanical species recognized for its significant biological potential. The plant's therapeutic value is primarily derived from its root and seed components. Specifically, the root bark is frequently utilized in various traditional preparations to harness its medicinal properties. Research indicates that this plant possesses notable neuroprotective activities, making it a subject of scientific interest. Understanding these characteristics is essential for exploring its role in supporting neurological health.
- Synonyms
- Celastrus Latifolius
- Common names
- Not available
- Family
- Celastraceae
- Distribution
- Not available
- Plant Parts
- Root · Seed
Classification
Common Names
Celastrus angulatus is a unique botanical species that is known by several different names depending on the region. In Czech-speaking areas, this plant is commonly referred to as bršlenec hranatý. Moving into Polish contexts, it is frequently identified by its local name, dławisz groniasty. These linguistic variations highlight the plant's presence across diverse European landscapes. Understanding these common names is essential for anyone studying the local flora of these specific regions.
Sources: Catalogue of Life (COL)
Synonyms
Celastrus angulatus is a botanical species that is frequently identified in scientific literature under a different name. It is widely recognized as being synonymous with Celastrus latifolius, a designation that can sometimes cause confusion for researchers. Understanding this nomenclatural link is essential for anyone studying the plant's classification and distribution. By acknowledging both names, botanists can more accurately track the species across various databases and historical texts. This connection ensures that information regarding its biological properties remains consistent and accessible.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Celastrus angulatus is a distinct biological entity that belongs to the vast kingdom Plantae. Within this expansive realm, the plant is classified under the class Equisetopsida. It further resides in the order Celastrales, which helps define its evolutionary lineage. As a member of the family Celastraceae, it shares specific characteristics with its botanical relatives. Ultimately, this species is defined by its placement within the genus Celastrus.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Celastrales |
| Family | Celastraceae |
| Genus | Celastrus |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Celastrus angulatus is a plant species primarily found throughout the temperate regions of Asia. Its natural distribution is concentrated within China, where it occupies several distinct geographical zones. Specifically, the species can be found across the North-Central territories of the country. It also thrives within the South-Central regions, showing significant adaptability to these varied climates. Furthermore, its presence extends into the Southeast part of China, rounding out its widespread regional reach.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Celastrus angulatus is a self-supporting plant that exhibits a distinct shrub-like growth form. This structural stability allows it to maintain its position within its natural habitat without the need for external support.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Celastrus angulatus has emerged as a significant subject of interest due to its potential neuroprotective properties. Recent research focused on the genus Celastrus has identified numerous β-dihydroagarofuran-type sesquiterpenoids within this specific plant species. These bioactive compounds demonstrated a remarkable ability to rescue cells from viability reduction induced by amyloid-beta toxicity. By protecting neural cells, these substances offer a promising chemical foundation for addressing complex neurodegenerative disorders like Alzheimer's disease. Consequently, the findings position these natural compounds as vital drug leads for the development of novel therapeutic agents.
Compounds
Celastrus angulatus serves as a significant source of specific chemical constituents found within its root bark. Through the use of silica gel column chromatography, researchers have successfully isolated various compounds from this plant species. Among these identified substances are angulatin A and angulatin B, which are predominant in the CGE A extract. Notably, the isolation of angulatin B from Celastrus angulatus represents a significant first in recent botanical studies. These specific chemical profiles are essential for establishing a reliable 1HNMR fingerprint used for the plant's authentication.
Conditions
Celastrus angulatus contains β-dihydroagarofuran-type sesquiterpenoids that serve as potential therapeutic agents against Alzheimer's disease. These specific compounds demonstrate neuroprotective capabilities by rescuing cell viability from Aβ25-35-induced reduction. Furthermore, the plant provides bioactive polyesters that exhibit significant anti-inflammatory activity. These isolated compounds effectively inhibit lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW264.7 macrophages. This inhibitory effect on nitric oxide follows a dose-dependent relationship, highlighting the medicinal utility of the species.
Preparations
Celastrus angulatus is prepared as root bark for various chemical analyses and studies. Researchers utilized the root bark to develop a specific 1HNMR fingerprint for the authentication of the species. Through silica gel column chromatography, the chemical constituents of the root bark were effectively separated. This preparation allowed for the isolation of key compounds such as angulatin A, B, and C. Consequently, the analyzed root bark serves as a vital tool for identifying the original plant source.
Parts used
Celastrus angulatus is a plant species of significant pharmacological interest due to its diverse chemical profile. Research has specifically focused on its root bark, where advanced analytical methods have identified a large family of sesquiterpenoids known as celangulins. Furthermore, the root bark serves as a valuable source for specialized compounds such as angulatin A, B, and C, which can be used for botanical authentication. Beyond the roots, the seeds of this plant have also been investigated, leading to the discovery of unique new sesquiterpenoids. Together, these findings highlight how different parts of the plant yield distinct and biologically relevant chemical constituents.