blue cohosh

Caulophyllum thalictroides · Accepted scientific name

Scientific literature: Very Extensive (537 studies) · ★★★★★

Blue cohosh, scientifically known as Caulophyllum thalictroides, is a perennial herb native to North American forests. Often distinguished by its striking blue-tinted stems, this botanical species has been historically valued in traditional medicine for its diverse therapeutic properties, particularly regarding reproductive health and its potential anti-inflammatory effects.

Family
Berberidaceae
Native range
Northern America
Parts used
Rhizome
Common names
Blue Cohosh · Papoose-Root · 2 more
Scientific synonyms
Leontice Thalictroides

Names

Common Names

Regional and Traditional Names

French:

  • caulophylle faux-pigamon
  • cohosh bleu
  • léontice faux-pigamon

Scientific Names

Accepted name

Caulophyllum thalictroides

Synonyms

Taxonomical Classification

This plant belongs to the kingdom Plantae within the phylum Streptophyta and is classified under the class Equisetopsida. As a member of the subclass Magnoliidae and order Ranunculales, it is further nested within the family Berberidaceae. Finally, it is specifically identified under the genus Caulophyllum.

Rank Classification Source
Kingdom Plantae WCVP
Phylum Streptophyta WCVP
Class Equisetopsida WCVP
Subclass Magnoliidae WCVP
Order Ranunculales WCVP
Family Berberidaceae WCVP
Genus Caulophyllum WCVP

Distribution

This plant exhibits a broad geographical distribution across several regions of North America. In Western Canada, its presence is noted within the province of Manitoba. Moving toward the east, the species can be found in the provinces of Ontario, Québec, and New Brunswick. Its range also extends into the North-Central United States, specifically within the state of Illinois. Collectively, these locations highlight the diverse environments where the plant thrives.

Region Area Source
Western Canada Manitoba WCVP
Eastern Canada New Brunswick WCVP
Eastern Canada Ontario WCVP
Eastern Canada Québec WCVP
North-Central U.S.A. Illinois WCVP
North-Central U.S.A. Iowa WCVP
North-Central U.S.A. Kansas WCVP
North-Central U.S.A. Minnesota WCVP
North-Central U.S.A. Missouri WCVP
North-Central U.S.A. North Dakota WCVP

Plant Parts

This plant possesses specific anatomical structures that contribute to its medicinal profile, particularly within its underground parts. The rhizomes serve as the primary subterranean organ, functioning as a storage system for nutrients and essential compounds that characterize the species. These thickened, horizontal stems grow beneath the soil surface, allowing the plant to persist through various environmental conditions while concentrating the bioactive elements used in herbal preparations.
Plant Part Sources Consensus
rhizome Journal of natural products (and other 1 sources) ★☆☆☆☆

Chemicals

Caulophyllum thalictroides has 59 reported phytochemicals identified across 1 scientific publications and several other databases. The most consistently reported chemicals include ANAGYRINE, Baptifoline, Magnoflorine, (-)-Anagyrine, (-)-Baptifoline.

Chemicals reported in Caulophyllum thalictroides
Chemical Supporting sources Consensus
ANAGYRINE 2 supporting sources ★☆☆☆☆
Baptifoline 2 supporting sources ★☆☆☆☆
Magnoflorine 2 supporting sources ★☆☆☆☆
(-)-Anagyrine 1 supporting sources ★☆☆☆☆
(-)-Baptifoline 1 supporting sources ★☆☆☆☆
ALUMINUM 1 supporting sources ★☆☆☆☆
Ash 1 supporting sources ★☆☆☆☆
BETA-SITOSTEROL 1 supporting sources ★☆☆☆☆
CALCIUM 1 supporting sources ★☆☆☆☆
CAMPESTEROL 1 supporting sources ★☆☆☆☆

ANAGYRINE

  1. Dr. Duke
  2. Journal of natural products

Baptifoline

  1. Dr. Duke
  2. Journal of natural products

Magnoflorine

  1. Dr. Duke
  2. Journal of natural products

(-)-Anagyrine

  1. Dr. Duke

(-)-Baptifoline

  1. Dr. Duke

ALUMINUM

  1. Dr. Duke

Ash

  1. Dr. Duke

BETA-SITOSTEROL

  1. Dr. Duke

CALCIUM

  1. Dr. Duke

CAMPESTEROL

  1. Dr. Duke

Activities

Caulophyllum thalictroides has 469 reported activities identified across 1 scientific publications and several other databases. The most consistently reported activities include (+)-Inotropic, 5-Alpha-Reductase-Inhibitor, ACE-Inhibitor, AP-1-Inhibitor, Abortifacient.

Most Reported Activities

Activity Sources Consensus
(+)-Inotropic Dr. Duke (and other 1 sources) ★☆☆☆☆
5-Alpha-Reductase-Inhibitor Dr. Duke (and other 1 sources) ★☆☆☆☆
ACE-Inhibitor Dr. Duke (and other 1 sources) ★☆☆☆☆
AP-1-Inhibitor Dr. Duke (and other 1 sources) ★☆☆☆☆
Abortifacient Dr. Duke (and other 1 sources) ★☆☆☆☆
Absorbent Dr. Duke (and other 1 sources) ★☆☆☆☆
Acetylcholinergic Dr. Duke (and other 1 sources) ★☆☆☆☆
Acidulant Dr. Duke (and other 1 sources) ★☆☆☆☆
Adrenolytic Dr. Duke (and other 1 sources) ★☆☆☆☆
Aldose-Reductase-Inhibitor Dr. Duke (and other 1 sources) ★☆☆☆☆

Medicinal Uses

Caulophyllum thalictroides has 1 reported medicinal uses identified across 1 scientific publications and several other databases. The most consistently reported uses include hepatoma.

Most Reported Uses

Use Sources Consensus
hepatoma Phytotherapy research : PTR (and other 1 sources) ★☆☆☆☆

Preparations

Preparations Sources Consensus
underground parts Journal of natural products (and other 1 sources) ★☆☆☆☆