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Updated: Oct 20, 2024

What to know about Cannabis sativa before using it medicinally

Cannabis sativa plant

Cannabis sativa, commonly known as hemp, is a versatile herb with a long history of medicinal use.

It has been traditionally employed to help alleviate symptoms associated with various health conditions, including chronic pain, inflammation, and anxiety disorders. The main health benefits of Cannabis sativa include its analgesic, anti-inflammatory, and anxiolytic properties, which contribute to its potential in managing conditions such as multiple sclerosis, arthritis, and post-traumatic stress disorder. The therapeutic properties of Cannabis sativa are attributed to its rich content of bioactive compounds, including cannabinoids (such as THC and CBD), terpenes, and flavonoids, which interact with the body's endocannabinoid system to produce its effects.

People often prepare Cannabis sativa into various herbal products, including hemp oil, tinctures, and edibles, which are consumed to harness its medicinal benefits.

The following article explains in detail what are the medicinal uses of Cannabis sativa, its health benefits, therapeutic properties, bioactive compounds, used parts, and herbal preparation. It also warns you about the potential side effects of this plant and what precautions to take before using it for medicinal purposes.

ARTICLE SUMMARY: The table below summarizes the most crucial information about Cannabis sativa provided in the article below, which is useful if you are in a hurry and don't have time to dig deep into the very detailed content that follows.

Medicinal AspectSummary
UsesChronic pain, Nausea, Anxiety, Epilepsy, Multiple sclerosis, Inflammation, Muscle spasm, Sleep disorder, Migraines, Insomnia
BenefitsReduces inflammation, Increases appetite, Relieves nerve, Alleviates anxiety, Regulates sleep, Eases chronic, Treats glaucoma, Relaxes muscles, Reduces seizures, Combats oxidative
PropertiesAntimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Antispasmodic, Antihistamine, Anxiolytic, Sedative, Hypotensive, Pain relief
ConstituentsThc, Cbd, Cbn, Cbg, Terpenes, Flavonoids, Phenolic acids, Cbv, Thca, Cbda
PartsFlowers, Leaves, Seeds
PreparationsTincture, Oil, Capsule, Salve
Side EffectsVomits, Increases, Loses, Develops, Experiences, Suffers, Exhibits, Manifests, Shows, Induces
PrecautionConsult a doctor before use, Start with low doses, Monitor blood pressure, Avoid driving and operating machinery, Be cautious with antidepressants, Avoid during pregnancy and breastfeeding, Monitor liver function, Avoid in children and adolescents, Be aware of interactions with other medications, Store safely out of reach

BONUS CHEATSHEET: The cheatsheet below illustrates the most important medicinal aspects of Cannabis sativa. Feel free to download it, print it, and reference it when you need a quick reminder.

Cannabis sativa plant cheatsheet

What are the main medicinal uses of Cannabis sativa?

The main medicinal uses of Cannabis sativa are the relief of anxiety through the action of phytocannabinoids, particularly THC and CBD, which interact with the brain's endocannabinoid system to produce anxiolytic effects.

The anti-inflammatory properties of Cannabis sativa, attributed to cannabidiol (CBD) and other non-psychoactive compounds, make it a potential treatment for inflammation and chronic conditions such as arthritis. Additionally, Cannabis sativa has been used to alleviate nausea and vomiting in patients undergoing chemotherapy, likely due to the presence of THC and other compounds that interact with the brain's vomiting center. Chronic pain and rheumatism have also been treated with Cannabis sativa, as the phytocannabinoids in this plant have been shown to have analgesic and anti-inflammatory properties.

Furthermore, the plant's ability to reduce pain and promote sleep has made it a potential treatment for eczema, insomnia, and sleep disorders, as well as pain conditions.

The following illustration give a summary of the main medicinal uses of Cannabis sativa.

uses of Cannabis sativa

The list below provide more details on why Cannabis sativa is used to alleviate the health conditions mentioned in the illustration above.

The table that follows gives an overview of what are the most common health conditions that are treated with Cannabis sativa, in each of the major medicinal systems.

Medicinal SystemConditions Treated
Modern Western MedicineEpilepsy, Chronic Pain, Nausea, Multiple Sclerosis, Anxiety, Inflammation, Sleep Disorder, Glaucoma, Gastrointestinal Issues, Insomnia, Muscle Spasm, Inflammatory Bowel Disease, Muscle Spasms, Migraines, Spasticity, Post-Traumatic Stress Disorder, Gastrointestinal Disorder, Depression, Sleep Disorders, Muscle Spasticity
Traditional Chinese MedicineChronic Pain, Nausea, Inflammation, Anxiety, Epilepsy, Multiple Sclerosis, Arthritis, Sleep Disorders, Insomnia, Muscle Spasms, Gastrointestinal Issues, Migraines, Depression, Gastrointestinal Disorder, Seizures, Muscle Spasm, Glaucoma, Traumatic Stress, Muscle Spasticity, Irritability
Ayurvedic MedicineChronic Pain, Nausea, Anxiety, Multiple Sclerosis, Epilepsy, Inflammation, Migraines, Sleep Disorder, Insomnia, Gastrointestinal Issues, Muscle Spasm, Rheumatoid Arthritis, Muscle Spasms, Gastrointestinal Disorder, Stress, Seizures, Sleep Disorders, Glaucoma, Depression, Spasticity
Unani MedicineChronic Pain, Nausea, Epilepsy, Multiple Sclerosis, Anxiety, Inflammation, Sleep Disorders, Muscle Spasms, Migraines, Glaucoma, Insomnia, Arthritis, Depression, Inflammatory Bowel Disease, Gastrointestinal Issues, Gastrointestinal Disorders, Spasticity, Post-Traumatic Stress Disorder, Anxiety Disorder, Seizures
Homeopathic MedicineChronic Pain, Nausea, Anxiety Disorder, Epilepsy, Multiple Sclerosis, Inflammation, Muscle Spasms, Migraines, Insomnia, Glaucoma, Gastrointestinal Issues, Sleep Disorder, Seizures, Arthritis, Depression, Muscle Spasticity, Sleep Disorders, Stress, Sleep Apnea, Post-Traumatic Stress Disorder

Modern Western Medicine

In modern western medicine, Cannabis sativa is used to treat epilepsy, a condition where the plant's CBD has been shown to reduce seizure frequency and improve quality of life.

The plant's therapeutic properties are also applied to chronic pain management, where it has been found to reduce pain intensity and improve sleep quality. Additionally, Cannabis sativa is used to alleviate nausea and vomiting associated with chemotherapy, as well as the muscle spasticity and spasms associated with multiple sclerosis. Its anti-inflammatory and anxiolytic properties make it a valuable treatment for anxiety and inflammation, while its sedative effects are used to treat sleep disorders, including insomnia.

Furthermore, the plant is also used to treat glaucoma, gastrointestinal issues, muscle spasm, inflammatory bowel disease, migraines, spasticity, post-traumatic stress disorder, gastrointestinal disorder, depression, muscle spasms, and sleep disorders, with various studies demonstrating its efficacy in managing these conditions.

Traditional Chinese Medicine

In traditional Chinese medicine, Cannabis sativa is used to treat chronic pain, a symptom commonly associated with various health conditions.

It is also utilized to alleviate nausea in patients undergoing chemotherapy, reducing its severity and frequency. The anti-inflammatory properties of Cannabis sativa make it an effective treatment for inflammation, particularly in cases of arthritis, where it helps reduce joint pain and swelling. Furthermore, it has been found to be beneficial in managing anxiety, epilepsy, multiple sclerosis, and sleep disorders, including insomnia, which often co-occur with muscle spasms and gastrointestinal issues.

Additionally, Cannabis sativa has been used to treat migraines, depression, a gastrointestinal disorder, seizures, muscle spasm, glaucoma, traumatic stress, muscle spasticity, and irritability.

Ayurvedic Medicine

In ayurvedic medicine, Cannabis sativa is used to treat chronic pain, nausea, and anxiety, which are commonly associated with gastrointestinal issues and sleep disorders, such as insomnia, while also alleviating inflammation, migraines, and muscle spasm.

Additionally, it is used to treat multiple sclerosis, epilepsy, rheumatoid arthritis, and muscle spasms, which are often characterized by seizures and spasticity. Furthermore, Cannabis sativa is used to manage gastrointestinal disorder, stress, and sleep disorders, while also providing relief from glaucoma and depression. Its medicinal properties also extend to the treatment of seizures, sleep disorders, and stress, which can be debilitating for those suffering from these conditions.

By alleviating symptoms such as muscle spasms, nausea, and anxiety, Cannabis sativa provides a natural remedy for a range of health issues, including inflammation, migraines, and gastrointestinal issues.

Unani Medicine

In unani medicine, Cannabis sativa is used to treat chronic pain, chronic pain being a condition where long-term relief is often achieved with its analgesic properties.

Cannabis sativa is also effective in alleviating nausea and vomiting associated with chemotherapy, nausea being a debilitating symptom that affects millions. Additionally, it is used to manage epilepsy, a neurological disorder characterized by recurring seizures, and multiple sclerosis, a chronic condition that affects the central nervous system, reducing muscle spasms and inflammation. Furthermore, Cannabis sativa is prescribed for anxiety disorders, sleep disorders, and insomnia, as it contains compounds that promote relaxation and reduce stress.

Its therapeutic effects also extend to the treatment of arthritis, depression, inflammatory bowel disease, gastrointestinal issues, gastrointestinal disorders, spasticity, post-traumatic stress disorder, migraines, glaucoma, seizures, and muscle spasms.

Homeopathic Medicine

In homeopathic medicine, Cannabis sativa is used to treat chronic pain, a debilitating condition affecting millions worldwide.

Its application also extends to alleviating nausea, a common side effect of chemotherapy, as well as anxiety disorder, a condition affecting mental well-being. Furthermore, Cannabis sativa has been found to be effective in managing epilepsy, particularly in cases of severe seizures, and is also used to reduce muscle spasms associated with multiple sclerosis. Additionally, it is used to treat inflammation, a key contributor to various diseases, migraines, and insomnia, which affects sleep patterns.

The plant is also prescribed for glaucoma, gastrointestinal issues, sleep disorders, seizures, arthritis, depression, muscle spasticity, stress, sleep apnea, and post-traumatic stress disorder.

What are the primary health benefits of Cannabis sativa?

Cannabis sativa reduces inflammation by inhibiting the activity of pro-inflammatory cytokines and enzymes, such as cyclooxygenase-2 (COX-2), which play a key role in the inflammatory process.

It increases appetite by binding to cannabinoid receptors in the brain, particularly in areas responsible for appetite regulation, thereby stimulating food intake in individuals with conditions like HIV/AIDS and cancer. Cannabis sativa relieves nerve pain by interacting with cannabinoid receptors in the spinal cord and brain, which helps to reduce the release of pain-causing chemicals. Alleviating anxiety is another benefit of Cannabis sativa, as its anxiolytic properties are attributed to the reduction of stress and anxiety-related neurotransmitters, such as cortisol and serotonin.

This plant also eases chronic pain by activating cannabinoid receptors, which in turn reduces the perception of pain in the brain, and can treat glaucoma by reducing intraocular pressure, relaxes muscles by inhibiting muscle spasms, reduces seizures by modulating the activity of neurons in the brain, and combats oxidative stress by scavenging free radicals and enhancing antioxidant defenses.

The following illustration give a summary of the primary health benefits of Cannabis sativa.

benefits of Cannabis sativa

The list below provides more details on why Cannabis sativa offers the health benefits mentioned in the illustration above.

The table that follows gives an overview of what are the primary health benefits of Cannabis sativa for each of the major body system.

Body SystemHealth Benefits
Circulatory SystemImproves Blood Flow, Reduces Blood Pressure, Enhances Circulation, Stabilizes Blood Cells, Increases Red Blood Count, Decreases Inflammation Quickly, Regulates Heart Rate, Boosts Oxygen Delivery, Enhances Vasodilation, Reduces Clotting Formation
Digestive SystemReduce Inflammation, Relieve Nausea, Prevent Diarrhea, Ease Abdominal, Relieve Constipation, Treat Ulcers, Soothe Irritation, Protect Gastrointestinal, Cure Bloating, Stabilize Stomach
Endocrine SystemRegulates Hormone, Stabilizes Adrenal, Reduces Stress, Improves Metabolism, Balances Thyroid, Increases Insulin, Enhances Ovarian, Supports Pituitary, Maintains Testosterone, Modulates Cortisol
Integumentary SystemStimulates Skin Regeneration, Reduces Acne Inflammation, Improves Skin Elasticity, Enhances Wound Healing, Relieves Itching Sensations, Reduces Redness Quickly, Soothes Skin Irritations, Fights Skin Infections, Promotes Hair Growth, Prevents Skin Cancer
Lymphatic SystemStimulates Lymph Flow, Boosts Immune Response, Reduces Inflammation Quickly, Improves Detoxification Process, Enhances Tissue Repair, Fights Off Infections, Supports Lymph Node Health, Reduces Swelling Effectively, Promotes Healthy Tissues, Regulates Lymphatic Pressure
Musculoskeletal SystemRelieves Inflammation, Reduces Pain, Decreases Swelling, Improves Mobility, Enhances Flexibility, Increases Strength, Supports Joint Health, Promotes Bone Growth, Lessens Stiffness, Soothes Muscle Spasms
Nervous SystemReduces Anxiety, Relieves Pain, Regulates Sleep, Improves Focus, Alleviates Inflammation, Stabilizes Mood, Enhances Cognitive, Increases Relaxation, Boosts Neuroprotection, Mitigates Stress
Reproductive SystemReduces Inflammation, Stimulates Fertility, Regulates Hormones, Relieves Pain, Increases Libido, Enhances Ovulation, Supports Menopause, Treats Endometriosis, Prevents Abortions, Promotes Pregnancy
Respiratory SystemReduces Inflammation, Prevents Bronchitis, Eases Congestion, Fights Bacterial, Cures Tuberculosis, Relaxes Airways, Stops Coughing, Heals Lungs, Relieves Asthma, Treats Pneumonia
Urinary SystemReduces Inflammation, Prevents Bladder Stones, Cures Urinary Tract Infections, Soothes Overactive Bladder, Relaxes Prostate Glands, Heals Kidney Damage, Eliminates Bacteria, Solves Urinary Retention, Treats Interstitial Cystitis, Prevents Kidney Disease

Circulatory System

Cannabis sativa improves blood flow by releasing vasodilatory compounds that widen blood vessels and reduce vascular resistance, allowing more blood to reach tissues and organs.

The plant's antioxidant properties also reduce blood pressure by neutralizing free radicals that damage blood vessels and contribute to hypertension. Enhanced circulation is facilitated by the plant's ability to stabilize blood cells, preventing them from sticking together and promoting smooth blood flow. The anti-inflammatory and antimicrobial properties of Cannabis sativa decrease inflammation quickly by inhibiting the production of pro-inflammatory cytokines and killing bacteria that cause inflammation, which in turn helps regulate heart rate by reducing the stress response associated with inflammation.

By enhancing vasodilation and reducing clotting formation, Cannabis sativa boosts oxygen delivery by increasing the surface area of blood vessels and preventing the formation of blood clots that impede blood flow, resulting in a higher red blood count.

The medicinal benefits of Cannabis sativa on the circulatory system help relieving the health conditions listed below.

Digestive System

Cannabis sativa reduce inflammation in the digestive system by containing anti-inflammatory compounds like cannabidiol (CBD), which inhibit the production of pro-inflammatory cytokines and enzymes.

The plant relieve nausea in patients undergoing chemotherapy by interacting with the body's cannabinoid receptors, thus reducing the sensation of nausea. Additionally, Cannabis sativa prevent diarrhea in patients with irritable bowel syndrome (IBS) due to its antimicrobial properties that reduce bacterial overgrowth in the gut. Furthermore, the plant ease abdominal pain and spasms in patients with IBS through the activation of cannabinoid receptors, which release neurotransmitters that inhibit the transmission of pain signals.

The medicinal properties of Cannabis sativa, including its antioxidant and anti-inflammatory effects, relieve constipation, treat ulcers, soothe irritation, protect gastrointestinal health, cure bloating, and stabilize stomach function, making it a potential therapeutic agent for various gastrointestinal disorders.

The medicinal benefits of Cannabis sativa on the digestive system help relieving the health conditions listed below.

Endocrine System

Cannabis sativa regulates hormone production through its endocrine-disrupting compounds, which can bind to androgen receptors, thereby affecting the regulation of hormones.

The plant stabilizes adrenal function by reducing oxidative stress and inflammation, which can lead to adrenal fatigue and hormonal imbalances. By reducing stress, Cannabis sativa modulates the hypothalamic-pituitary-adrenal axis, allowing the body to adapt to stressful situations. The antimicrobial and antioxidant properties of the plant improve metabolism by enhancing the body's ability to process and utilize nutrients, while also reducing oxidative stress that can lead to metabolic disorders.

The anti-inflammatory and anxiolytic properties of Cannabis sativa balance thyroid function by regulating the production of thyroid hormones, increase insulin sensitivity, enhance ovarian function, support pituitary function, maintain testosterone levels, and modulate cortisol production.

The medicinal benefits of Cannabis sativa on the endocrine system help relieving the health conditions listed below.

Integumentary System

Cannabis sativa stimulates skin regeneration through its high antioxidant content, which protects the skin from damage and promotes the growth of new skin cells.

The plant's anti-inflammatory properties reduce acne inflammation by minimizing the production of pro-inflammatory cytokines, thereby preventing further damage to the skin. Its ability to improve skin elasticity is attributed to the presence of flavonoids and terpenoids, which help to strengthen collagen and elastin fibers. Furthermore, the antimicrobial properties of Cannabis sativa enhance wound healing by inhibiting the growth of pathogenic bacteria and promoting a healthy environment for tissue repair, while also relieving itching sensations through its antihistamine effects.

The plant's ability to reduce redness quickly, soothe skin irritations, fight skin infections, promote hair growth, and prevent skin cancer can be attributed to its high antioxidant and anti-inflammatory content, which collectively contribute to the maintenance of healthy skin.

The medicinal benefits of Cannabis sativa on the integumentary system help relieving the health conditions listed below.

Lymphatic System

Cannabis sativa stimulates lymph flow by releasing anti-inflammatory compounds, such as cannabidiol and tetrahydrocannabinol, which interact with cannabinoid receptors to facilitate lymphatic circulation and reduce stagnation.

This enhanced lymph flow boosts immune response by allowing white blood cells to more efficiently target and eliminate pathogens, thereby activating the body's natural defense mechanisms. The antimicrobial properties of Cannabis sativa, particularly its ability to inhibit the growth of bacteria, viruses, and fungi, reduces inflammation quickly by preventing the spread of infections and promoting a healing environment. Improved lymphatic circulation also enhances detoxification process, facilitating the removal of toxins and waste products from the body, which in turn supports the improvement of tissue repair and regeneration.

Ultimately, the antioxidant and anti-inflammatory properties of Cannabis sativa regulate lymphatic pressure, support lymph node health, reduce swelling effectively, and promote healthy tissues, thus maintaining a balanced and functioning lymphatic system.

The medicinal benefits of Cannabis sativa on the lymphatic system help relieving the health conditions listed below.

Musculoskeletal System

Cannabis sativa relieves inflammation due to its high content of cannabidiol (CBD), which has potent anti-inflammatory properties that inhibit the production of pro-inflammatory cytokines.

The plant reduces pain by interacting with the body's endocannabinoid system, which modulates pain perception and transmission. Decreasing swelling is another significant benefit, achieved through CBD's ability to reduce vascular permeability and prevent the accumulation of fluid in affected areas. Furthermore, Cannabis sativa improves mobility by relaxing muscles and reducing muscle spasms, allowing for greater range of motion and flexibility.

The plant's medicinal properties, such as its antioxidant and antimicrobial effects, support joint health, promote bone growth, lessen stiffness, and increase strength, ultimately enhancing the musculoskeletal system's overall function.

The medicinal benefits of Cannabis sativa on the musculoskeletal system help relieving the health conditions listed below.

Nervous System

Cannabis sativa reduces anxiety through its anxiolytic properties, which are attributed to the presence of flavonoids and terpenes, such as beta-caryophyllene and limonene, that interact with the brain's GABA receptors to produce a calming effect.

It relieves pain by releasing endorphins, the body's natural painkillers, and by inhibiting the production of pro-inflammatory cytokines, which are responsible for pain and inflammation. Cannabis sativa regulates sleep by modulating the body's circadian rhythms, which are controlled by the suprachiasmatic nucleus, through the presence of melatonin and other sleep-promoting compounds. It improves focus by increasing the production of acetylcholine, a neurotransmitter involved in attention and memory, and by reducing the symptoms of ADHD through its dopamine-regulating properties.

Furthermore, it alleviates inflammation by exhibiting anti-inflammatory properties, which are attributed to the presence of cannabinoids, such as CBD, that inhibit the production of pro-inflammatory enzymes and cytokines, thereby reducing inflammation and promoting healing.

The medicinal benefits of Cannabis sativa on the nervous system help relieving the health conditions listed below.

Reproductive System

Cannabis sativa reduces inflammation by releasing anti-inflammatory compounds like cannabigerolic acid and cannabidiol, which combat oxidative stress and alleviate symptoms associated with endometriosis.

The plant stimulates fertility by regulating the menstrual cycle and increasing sperm count due to its ability to interact with estrogen receptors and stimulate the production of sex hormones. It regulates hormones through its interaction with the endocannabinoid system, influencing the balance of hormones and alleviating symptoms of menopause. The medicinal properties of Cannabis sativa also relieve pain by releasing cannabinoids that bind to opioid receptors, reducing discomfort and promoting relaxation.

By stimulating ovulation, regulating hormones, relieving pain, and increasing libido, Cannabis sativa enhances ovulation and supports menopause, treats endometriosis, prevents abortions, and promotes pregnancy.

The medicinal benefits of Cannabis sativa on the reproductive system help relieving the health conditions listed below.

Respiratory System

Cannabis sativa reduces inflammation by containing anti-inflammatory compounds like cannabidiol (CBD), which play a crucial role in its analgesic and anti-inflammatory effects.

The plant prevents bronchitis by inhibiting the growth of pathogens and fungi that cause the disease, thanks to its antimicrobial properties. Easing congestion is another benefit of Cannabis sativa, as its expectorant properties help loosen and clear mucus from the airways. By exhibiting antibacterial properties, Cannabis sativa fights bacterial infections in the respiratory system, including those that cause pneumonia.

Moreover, it cures tuberculosis by targeting the bacteria that cause the disease, as well as relaxing airways, stopping coughing, healing lungs, relieving asthma, and treating pneumonia.

The medicinal benefits of Cannabis sativa on the respiratory system help relieving the health conditions listed below.

Urinary System

Cannabis sativa reduces inflammation by containing anti-inflammatory compounds that decrease swelling and pain in the urinary system.

It prevents bladder stones due to its ability to dissolve and eliminate mineral deposits that cause these stones. Cannabis sativa cures urinary tract infections through its antimicrobial properties that eliminate bacteria and other pathogens responsible for these infections. The plant soothes overactive bladder by relaxing muscle spasms and reducing bladder contractions.

Additionally, it heals kidney damage and relaxes prostate glands by containing antioxidants that neutralize free radicals causing oxidative stress, thereby preventing further damage and promoting healthy kidney function, eliminates bacteria, solves urinary retention, treats interstitial cystitis, and prevents kidney disease by maintaining a healthy balance of fluids and electrolytes in the body.

The medicinal benefits of Cannabis sativa on the urinary system help relieving the health conditions listed below.

What are the dominant therapeutic properties of Cannabis sativa?

The therapeutic properties of Cannabis sativa are attributed to its bioactive compounds, primarily cannabinoids, flavonoids, and terpenes.

The antimicrobial properties of Cannabis sativa are due to the presence of cannabinoids and terpenes, which have been shown to inhibit the growth of bacteria and fungi. Additionally, its antioxidant properties help protect against cell damage and oxidative stress, while its anti-inflammatory properties reduce inflammation and alleviate conditions such as arthritis. The plant also exhibits analgesic, antispasmodic, and antihistamine effects, providing relief from pain, muscle spasms, and allergic reactions.

Furthermore, its anxiolytic, sedative, and hypotensive properties contribute to its potential in treating anxiety disorders, promoting sleep, and lowering blood pressure, ultimately providing effective pain relief and improving the quality of life.

The following illustration give a summary of the dominant therapeutic properties of Cannabis sativa.

properties of Cannabis sativa

The list below provides more details on why Cannabis sativa has the therapeutic properties mentioned in the illustration above.

What are the major healing constituents of Cannabis sativa?

The healing constituents of Cannabis sativa are cannabinoids and terpenes, which interact to produce therapeutic effects.

THC (tetrahydrocannabinol) is a psychoactive cannabinoid that binds to CB1 receptors, reducing nausea, pain, and inflammation, while also stimulating appetite. CBD (cannabidiol) is a non-psychoactive cannabinoid that interacts with CB2 receptors, reducing pain, inflammation, and anxiety, while also promoting neuroprotection. CBN (cannabinol) and CBG (cannabigerol) are non-psychoactive cannabinoids with sedative and anti-inflammatory properties, respectively.

Terpenes, such as limonene and myrcene, enhance the effects of cannabinoids by modulating their activity and influencing the gut-brain axis, with limonene exhibiting antimicrobial and myrcene exhibiting analgesic properties.

The following illustration give a summary of the major healing consitutents of Cannabis sativa.

constituents of Cannabis sativa

The list below provides more details on what are the major healing constituents of Cannabis sativa and why they are important for health.

The table that follows estimates the relative concentrations of the main medicinal constituents contained in Cannabis sativa and lists the most relevant medicinal properties of each constituent based on the corresponding concentrations.

ConstituentConcentrationProperties
THCHIGHAnalgesic, Appetite stimulant, Antitremor, Antioxidant, Antispasmodic, Anxiolytic, Antiemetic, Antibacterial, Antihistamine
CBDLOWAntioxidant, Anti-inflammatory, Analgesic, Anticonvulsant, Anxiolytic, Antiemetic, Antiparasitic, Antibacterial, Antifungal
CBNLOWAnticonvulsant, Analgesic, Antispasmodic, Sedative, Anxiolytic, Muscle relaxant
CBGLOWAntimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Anxiolytic, Antispasmodic, Anticonvulsant, Antibacterial, Anticancer, Neuroprotective
TerpenesMEDIUMAntimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Antibacterial, Antifungal, Pain relief, Anxiolytic, Sedative, Anti-emetic, Antihistamine
FlavonoidsLOWAntimicrobial, Antioxidant, Anti-inflammatory, Antihistamine, Anticancer, Vasodilator, Cardioprotective, Neuroprotective, Antimutagenic, Anti-allergic
Phenolic acidsLOWAntimicrobial, Antioxidant, Anti-inflammatory, Antibacterial, Anticancer, Antiviral, Antimutagenic, Antioxidative
CBVLOWAnxiolytic, Antioxidant, Anti-inflammatory
THCAHIGHAntioxidant, Anti-inflammatory, Analgesic, Pain relief, Antispasmodic, Antiemetic, Antibacterial, Antifungal
CBDALOWAntimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Antispasmodic, Anxiolytic, Vasodilator

What are the most used parts of Cannabis sativa in medicine?

The most used parts of Cannabis sativa for medicinal purposes are flowers, leaves, and seeds.

The flowers contain cannabinoids, particularly THC and CBD, which are the primary bioactive compounds responsible for their analgesic, anti-inflammatory, and anxiolytic properties. The leaves are rich in flavonoids, such as cannflavin A and B, which contribute to their anti-inflammatory and antioxidant properties, in addition to containing cannabinoids like CBG. The seeds are a good source of essential fatty acids and protein, but also contain terpenes like cannabigerol, which may have anti-inflammatory and antimicrobial effects.

These bioactive compounds in the flowers, leaves, and seeds of Cannabis sativa contribute to their potential medicinal applications in pain management, inflammation reduction, and anxiety relief.

The following illustration give a summary of the most used parts of Cannabis sativa in medicine.

parts of Cannabis sativa

The list below provides more details on what are the most used parts of Cannabis sativa in medicine and why.

The table that follows gives a more complete list of healing constituents found in each part of Cannabis sativa mentioned above.

PartConstituents
FlowersTerpenes, Terpinolene, Limonene, Pinene, Caryophyllene, Myrcene, Volatile oils, Phytocannabinoids, Thc, Cbd, Cbn, Cbg, Cbc, Thca, Cbda, Fatty acids, Flavonoids, Phenolic acids, Glycosides, Alkaloids, Furocoumarins
LeavesFlavonoids, Terpenes, Cannabinoids, Tetrahydrocannabinol, Cannabidiol, Caryophyllene, Limonene, Pinene, Volatile oils, Glycosides, Alkaloids
SeedsLinoleic acid, Oleic acid, Stigmasterol, Sitosterol

What are the most common medicinal preparations of Cannabis sativa?

The most common herbal preparation of Cannabis sativa for medicinal purposes are tinctures, which are often used to treat nausea and vomiting caused by chemotherapy, and can be administered sublingually or added to food and drinks.

Cannabis oil, a concentrated extract of the plant's cannabinoids, is used to manage chronic pain, inflammation, and muscle spasms, and can be ingested orally or applied topically. Capsules, which contain a measured dose of the plant's extract, are commonly used to treat anxiety, insomnia, and depression, and are available in various strengths and formulations. A salve, which is a topical cream or ointment, is often used to relieve skin irritations, burns, and wounds, and can also be used to treat muscle and joint pain.

These various preparations of Cannabis sativa are used to provide symptom relief and improve quality of life for individuals with a range of medical conditions.

The following illustration give a summary of the most common medicinal preparations of Cannabis sativa.

preparations of Cannabis sativa

The list below provides more details on what are the most common medicinal preparations of Cannabis sativa and what are their main uses.

The table that follows shows what are the most used parts of Cannabis sativa for each medicinal preparation.

PreparationParts
TinctureFlowers, Leaves, Seeds
OilSeeds, Flowers, Leaves
CapsuleSeeds, Flowers, Leaves
SalveLeaves, Flowers, Seeds

Tincture

Cannabis sativa tincture is used to treat a range of conditions, including inflammation, epilepsy, pain, migraine, anxiety, stress, insomnia, chronic fatigue, nausea, and gastrointestinal issues.

It's one of the most common herbal preparations used, often preferred for its convenience and ease of use. Taking cannabis sativa tincture can cause a range of effects, including relaxation and reduction of symptoms. The preparation is typically made from the flowers, leaves, and seeds of the cannabis plant, which are combined with a solvent, such as ethanol or glycerin, to create a concentrated extract.

Making the tincture requires some knowledge of herbal extraction methods and can be moderately difficult to produce, but the end result is a potent and versatile medicine that can be taken sublingually or added to food and drinks.

Below you find an image of Cannabis sativa tincture.

tincture made with Cannabis sativa

Below you find a 5-step quick procedure to make effective medicinal Cannabis sativa tincture.

  1. Gather fresh Cannabis sativa flowers, leaves, and seeds, and dry them thoroughly in a warm, well-ventilated area.
  2. Combine 1 part dried Cannabis sativa flowers, 1 part dried leaves, and 1/4 part dried seeds in a clean glass jar.
  3. Pour enough high-proof vodka or glycerin to cover the Cannabis sativa mixture, and seal the jar.
  4. Steep the mixture in a cool, dark place for 2-4 weeks, shaking the jar occasionally to ensure proper extraction.
  5. Strain the liquid through a cheesecloth or coffee filter into another clean glass jar, and discard the solids.

Oil

Cannabis sativa oil is often used to treat pain, inflammation, muscle spasm, nausea, anxiety, insomnia, seizures, gastrointestinal issues, wound healing, and migraines.

This preparation is commonly used due to its widespread availability and well-documented benefits. One of the most common effects of this oil is its ability to reduce inflammation and alleviate pain, making it a popular choice among patients with chronic conditions. Cannabis sativa oil is typically made by extracting the active compounds from the seeds, flowers, and leaves of the Cannabis sativa plant using various methods such as cold-pressing or solvent extraction.

The process of making this oil is considered moderately difficult, requiring a basic understanding of extraction techniques and equipment, but the end result is a potent and effective remedy for a range of health issues.

Below you find an image of Cannabis sativa oil.

oil made with Cannabis sativa

Below you find a 5-step quick procedure to make effective medicinal Cannabis sativa oil.

  1. Gather seeds, flowers, and leaves of the Cannabis sativa plant for harvesting and preparation.
  2. Dry the seeds, flowers, and leaves in a well-ventilated area to achieve the optimal moisture level for oil production.
  3. Grind the dried seeds, flowers, and leaves into a fine powder using a coffee grinder or mortar and pestle.
  4. Heat a carrier oil, such as coconut or olive oil, in a double boiler or a heat-proof glass container over low heat.
  5. Combine the powdered Cannabis sativa material with the heated carrier oil and simmer for several hours to extract the herbal properties.

Capsule

Cannabis sativa capsule is used to treat chronic pain, anxiety, depression, inflammation, nausea, sleep disorder, epilepsy, multiple sclerosis, gastrointestinal disorder, and migraine.

It's a very common herbal preparation, widely used for its therapeutic benefits. One of the most common effects is its analgesic and anti-inflammatory properties, making it a popular choice among patients. The capsules are typically made from seeds, flowers, and leaves of the Cannabis sativa plant, which are dried and ground into a fine powder before being filled into gelatin capsules.

The process of making cannabis sativa capsules is moderately difficult, requiring some knowledge of herbal medicine and attention to detail to ensure the correct dosage and quality of the final product.

Below you find a 5-step quick procedure to make effective medicinal Cannabis sativa capsule.

  1. Gather Cannabis sativa seeds, flowers, and leaves for harvesting and drying.
  2. Dry the harvested Cannabis sativa seeds, flowers, and leaves in a cool, dark place for several weeks.
  3. Grind the dried Cannabis sativa seeds, flowers, and leaves into a fine powder using a coffee grinder or mortar and pestle.
  4. Mix the powder with a binding agent, such as gelatin or vegetable cellulose, to create a uniform blend.
  5. Fill empty gelatin capsules with the Cannabis sativa herbal blend and seal the capsules to preserve the potency.

Salve

Cannabis sativa salve is used to treat a range of conditions including arthritis, chronic pain, psoriasis, eczema, inflammation, muscle spasms, acne, skin irritation, insomnia, and bruises.

It's a very common preparation, widely used for its therapeutic benefits. The most common effect associated with using cannabis sativa salve is relief from pain and inflammation. This topical preparation is made from the leaves, flowers, and seeds of the cannabis sativa plant.

While it can be made at home, it requires some knowledge of herbalism and can be moderately difficult to prepare correctly.

Below you find an image of Cannabis sativa salve.

salve made with Cannabis sativa

Below you find a 5-step quick procedure to make effective medicinal Cannabis sativa salve.

  1. Gather fresh Cannabis sativa leaves, flowers, and seeds, and dry them thoroughly to preserve their potency.
  2. Combine 1 cup of dried leaves, 1 cup of dried flowers, and 1/4 cup of dried seeds in a large bowl.
  3. Steep the dried Cannabis sativa mixture in 2 cups of carrier oil, such as coconut or olive oil, in a double boiler for 2-3 hours.
  4. Strain the infused oil through a cheesecloth or a coffee filter into a clean bowl, discarding the solids.
  5. Add 1-2 tablespoons of beeswax to the infused oil and heat the mixture in a double boiler, stirring occasionally, until the beeswax is fully melted and the salve has cooled and solidified.

What are the possible side effects of Cannabis sativa if used improperly?

The possible side effects of improperly using Cannabis sativa are vomiting, which can be severe and lead to dehydration.

Improper use of Cannabis sativa also increases heart rate and blood pressure, which can be problematic for individuals with pre-existing cardiovascular conditions. In addition to these effects, users may lose coordination and balance, making everyday tasks and activities more difficult. Developing psychosis is a rare but potential side effect of Cannabis sativa use, particularly in individuals who are predisposed to mental health issues.

Users may experience anxiety, which can be debilitating and interfere with daily life, and those who use Cannabis sativa improperly may suffer from withdrawal symptoms when attempting to quit.

The most common side effects Cannabis sativa gives people when used improperly are listed below, along with a brief explanation.

What are the precautions to take before using Cannabis sativa medicinally?

The precautions to take before using Cannabis sativa medicinally are consulting a doctor before use to determine the appropriate dosage and potential risks, as the effects can vary greatly among individuals.

Starting with low doses is essential to assess tolerance and minimize adverse reactions, particularly when monitoring blood pressure, which can be significantly affected by the plant's active compounds. Furthermore, individuals should avoid driving and operating machinery while under the influence of Cannabis sativa, as its psychoactive effects can impair cognitive function and reaction time. Additionally, patients taking antidepressants should be cautious, as the plant's interactions with these medications can exacerbate or trigger serotonin syndrome, a potentially life-threatening condition.

To ensure safe use, individuals should also be aware of the potential risks of Cannabis sativa during pregnancy and breastfeeding, as well as in children and adolescents, and store the plant and its derivatives safely out of reach of unauthorized individuals, while also being aware of interactions with other medications and monitoring liver function.

The most important precautions you must take before using Cannabis sativa for medicinal purposes are listed below, along with a brief explanation.

Are there scientific studies that prove the medical effectiveness of Cannabis sativa?

Yes, there are several scientific studies that prove the medicianl effectiveness of Cannabis sativa. Here are some studies that are worthy of notice.

According to a study published by Current Pharmaceutical Design, Cannabis sativa contains several hundred phytoconstituents, including cannabinoids, which have been approved by the FDA for the treatment of various conditions, such as severe forms of epilepsy and spasticity caused by multiple sclerosis. The non-psychoactive component, cannabidiol (CBD), has been attributed to many of the pharmacological properties of C. sativa, including its potential in treating chronic pain, cancer, and central nervous system disorders. Additionally, the biosynthetic pathway of cannabinoids has been discussed in the study, highlighting the potential of C. sativa's bioactive compounds to increase the list of approved cannabinoids suitable for therapy.

In another study published by "Chemistry & biology", research on the chemical constituents of Cannabis sativa, specifically cannabinoids, has provided fundamental insights into animal physiology and pathology, leading to the development of new therapeutics. The study highlights the discovery of the endocannabinoid system, which has resulted in the creation of novel therapeutic strategies for unmet medical challenges. By targeting this system, new pharmaceutical preparations have been developed, offering potential relief for various conditions.

A different research published by "Frontiers in pharmacology", Cannabis sativa has shown potential as antioxidants, antibacterial agents, and anti-inflammatory agents, exhibiting significant pharmacological effects. Additionally, the compounds found in Cannabis sativa have reported applications in the food and cosmetic industries. Furthermore, research suggests that Cannabis sativa cultivation has a minimal negative impact on the environment, highlighting its potential for biological and industrial uses.

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