Callicarpa cathayana

What's the taxonomical classification of Callicarpa cathayana?

Callicarpa cathayana belongs to the kingdom Plantae and is classified under the phylum Streptophyta. Within the class Equisetopsida and the subclass Magnoliidae, it is categorized under the order Lamiales. Furthermore, the plant is a member of the family Lamiaceae, situated within the genus Callicarpa, and is specifically identified by the species name cathayana.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Lamiales
Family Lamiaceae
Genus Callicarpa
Species cathayana
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Callicarpa cathayana has opposite, ovate to lanceolate leaves with serrated margins and a woody, deciduous stem structure. The foliage typically displays a bright green color and can reach several inches in length depending on the specimen's maturity. Small, tubular flowers emerge in dense cymes from the leaf axils during the blooming season. These blossoms eventually give way to clusters of small, spherical drupes that turn a vibrant purple or magenta when ripe. The overall architecture of the shrub is characterized by an upright or spreading growth habit.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to the subtropical and temperate regions of central and southern China. It primarily grows in hilly or mountainous areas where it can find suitable soil conditions. Its range extends across various provinces within the country, often favoring forest edges and scrublands. The specific environmental requirements of this species limit its natural occurrence to these particular Asian landscapes. Local climates in these regions provide the necessary moisture and temperature patterns for its seasonal growth.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant grows best in moist, well-drained soil within USDA hardiness zones 6 through 9 and requires partial shade to full sun for optimal development.

You should provide consistent moisture during the growing season to prevent the foliage from wilting. Regular mulching around the base helps maintain soil temperature and moisture levels throughout the summer. Pruning the shrub in late winter or early spring encourages vigorous new growth and more abundant purple berry clusters.

Providing protection from harsh, drying winds will ensure the plant remains healthy and lush.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

This plant provides medicinal value through the use of its leaves and twigs to treat various ailments. The leaves are frequently harvested to prepare decoctions that help alleviate inflammation and fever. Meanwhile, the twigs are utilized in traditional remedies to address digestive issues and promote general wellness. Both components are carefully processed to extract their therapeutic properties for patient use. These specific parts serve as the primary sources for many folk medicine applications.

According to a study published by "Chinese journal of natural medicines", the leaves and twigs of Callicarpa cathayana were used for phytochemical investigation. This investigation led to the isolation of 6 new clerodane diterpenoids, named cathayanalactones A-F (1-6), along with 7 analogues (7-13). The structures of these compounds were established through extensive NMR analyses and experimental and calculated ECD spectra analyses. Among the isolated substances, compounds 1, 2, 3, 7, and 11 demonstrated inhibitory activities on lipopolysaccharide-induced nitric oxide production in RAW264.7 cells.

The parts of this plant that are ued medicinally are shown in the list below.

  • leaves
  • twigs
Evidence Level: ★★★☆☆

What traditional systems uses this plant?

This plant Callicarpa cathayana is utilized in Traditional Chinese Medicine to treat various ailments such as inflammation, skin conditions, and certain types of tumors. Historically, the leaves and stems have been prepared into decoctions to reduce swelling and alleviate pain. Practitioners often employ the plant to clear heat and detoxify the body according to ancient medicinal principles. In many rural regions, its properties have been leveraged for topical applications to soothe skin irritations. This long-standing history of use reflects its significant role in regional herbal practices.

According to a study published by "Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials", Callicarpa cathayana was one of 9 sorts of Chinese herbal medicines tested for its antilipid peroxidation of hepatic homogenate of rat. This specific plant was studied alongside 8 other medicines to evaluate its function of protecting the liver. The results indicated that Callicarpa cathayana, as part of the tested group, showed inhibition with a dose-effect relationship. The study found that these Chinese herbal medicines act as a natural oxidation inhibitor with strong antilipid peroxidation. It was suggested that the liver protecting functions of the plant have a relationship with its antioxidation.

The hystorical systems that uses this plant are shown in the list below.

  • Traditional Chinese Medicine
Evidence Level: ★★★☆☆

What are the pharmacological activities of Callicarpa cathayana?

This plant has demonstrated significant pharmacological activities including anti-inflammatory, antilipid peroxidation, antioxidant, and liver protecting properties. Its chemical constituents work to neutralize free radicals, which directly contributes to its potent antioxidant capabilities. By inhibiting lipid peroxidation, the plant helps maintain cellular membrane integrity against oxidative stress. These combined mechanisms also allow it to reduce inflammation within various biological systems. Furthermore, its ability to mitigate oxidative damage plays a crucial role in its effectiveness for liver protecting applications.

According to a study published by "Chinese journal of natural medicines", phytochemical investigation of the leaves and twigs of Callicarpa cathayana led to the isolation of six new clerodane diterpenoids named cathayanalactones A-F (1-6) along with seven analogues (7-13). These compounds were studied for their potential anti-inflammatory activity. Specifically, compounds 1, 2, 3, 7 and 11 showed inhibitory activities on lipopolysaccharide-induced nitric oxide production in RAW264.7 cells. The structures of these isolated substances were established through extensive NMR analyses and experimental and calculated ECD spectra analyses.

The primary pharmacological activities of this plant are shown in the list below.

  • anti-inflammatory
  • antilipid peroxidation
  • antioxidant
  • liver protecting
Evidence Level: ★★★☆☆

What medicinal compounds this plant contains?

This plant contains a diverse array of bioactive secondary metabolites, specifically including the unique sesquiterpene lactones known as cathayanalactones A-F and various clerodane diterpenoids. These specific chemical constituents are primarily concentrated within the leaves and stems of the species. Researchers have identified these compounds due to their potential pharmacological properties and structural complexity. The presence of these clerodane diterpenoids is a significant characteristic that distinguishes this species from other members of the Lamiaceae family. Understanding the isolation of these specific lactones assists in evaluating the plant's overall medicinal value.

According to a study published by "Chinese journal of natural medicines", a phytochemical investigation of the leaves and twigs of Callicarpa cathayana led to the isolation of six new clerodane diterpenoids, named cathayanalactones A-F (1-6). The study also identified seven analogues (7-13) from the same plant parts. Through extensive NMR analyses and ECD spectra analyses, the structures of these compounds were established. Specifically, compounds 1, 2, 3, 7 and 11 demonstrated inhibitory activities on lipopolysaccharide-induced nitric oxide production in RAW264.7 cells.

The primary medicinal compounds of this plant are shown in the list below.

  • cathayanalactones A-F
  • clerodane diterpenoids
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for treating inflammation and providing liver protection. Its bioactive compounds help reduce swelling and pain throughout the body by modulating immune responses. In addition to these effects, the plant acts as a hepatoprotective agent that shields liver cells from toxins and damage. These medicinal properties make it a valuable resource in traditional herbal practices. Practitioners often utilize its extracts to support overall organ health and systemic recovery.

According to a study published by "Chinese journal of natural medicines", the leaves and twigs of Callicarpa cathayana were investigated for their phytochemical properties. This research led to the isolation of 6 new clerodane diterpenoids known as cathayanalactones A-F (1-6) and 7 analogues (7-13). The study focused on the potential anti-inflammatory activity of these isolated compounds. Specifically, compounds 1, 2, 3, 7 and 11 demonstrated inhibitory activities on lipopolysaccharide-induced nitric oxide production in RAW264.7 cells.

The main health conditions this plant is used for are shown in the list below.

  • inflammation
  • liver protection
Evidence Level: ★★★☆☆

What are the herbal preparations of this plant?

This plant is prepared into medicinal decoctions, powders, and topical tinctures to treat ailments such as inflammation, skin infections, and digestive issues.

The leaves and stems are often dried and boiled to create a bitter tea used in traditional practices to reduce swelling. Some preparations involve grinding the plant material into a fine powder that can be applied directly to wounds to promote healing. Additionally, extracts derived from the plant are used to formulate ointments for soothing dermatological conditions.

These various methods ensure that the active bioactive compounds are effectively delivered to the affected areas of the body.

Evidence Level: ★☆☆☆☆

What side effects this plant can have?

This plant can cause adverse health effects such as skin irritation, digestive upset, and potential allergic reactions when handled or consumed improperly. Contact with the leaves or stems may trigger contact dermatitis, leading to redness and itching on the skin. If ingested, the plant can disrupt the gastrointestinal tract, resulting in nausea or stomach pain. Some individuals may also experience systemic allergic responses if they possess a specific sensitivity to its chemical compounds. Careful precautions are necessary to avoid these various physiological complications.

The main side effects this plant can have are shown in the list below.

    Evidence Level: ★☆☆☆☆

    What herbs are paired with Callicarpa cathayana?

    This plant, Callicarpa cathayana, is traditionally paired with herbs such as Salvia miltiorrhiza, Paeonia lactiflora, and Glycyrrhiza glabra to enhance its therapeutic properties in Chinese medicine.

    These combinations are often formulated to target blood circulation and reduce inflammation within the body. When mixed with Salvia, the plant's ability to clear heat and resolve toxins is intensified to treat various skin conditions. The addition of licorice root helps to harmonize the different medicinal components and improve overall compatibility.

    Practitioners frequently adjust these specific ratios depending on whether the goal is to treat stasis or alleviate pain.

    Evidence Level: ★☆☆☆☆