10 Possible Side Effects Of Calendula Officinalis (Pot Marigold)

Calendula officinalis has some side effects when used improperly, such as skin irritation and allergic reactions.

These can occur due to excessive use or individual sensitivity. In severe cases, these side effects can lead to discomfort and compromised skin health, potentially affecting daily activities, self-esteem, and overall quality of life.

For instance, skin irritation can cause pain and itching, while allergic reactions can lead to more serious conditions like anaphylaxis.

This article explains in details the 10 most common side effects of Calendula officinalis if used imporperly.

1. Increases risk of toxicity

Calendula officinalis irritates skin surfaces due to its potent antibacterial and anti-inflammatory properties.

When applied topically, these active compounds can cause skin reactions in some individuals, leading to redness, itchiness, or burning sensations.

This adverse effect may occur because the herb's natural oils and sap can disrupt the skin's natural barrier function, triggering an immune response that manifests as irritation.

2. Increases risk of toxicity

Calendula officinalis causes allergic reactions in some individuals due to its ability to stimulate the immune system.

The plant's high concentration of flavonoids and terpenes can trigger an allergic response in people who are sensitive to these compounds.

As a result, users may experience symptoms such as itching, redness, and swelling at the site of application or in other areas of the body.

3. Increases risk of toxicity

Calendula officinalis triggers contact dermatitis due to its allergenic properties and the presence of sesquiterpene lactones in its essential oil.

These compounds can cause an allergic reaction when they come into contact with skin, leading to symptoms such as redness, itching, and blistering.

The exact mechanism behind this reaction is not fully understood, but it is thought that the immune system mistakenly identifies the plant's chemicals as foreign and mounts a response against them, resulting in inflammation and discomfort.

4. Increases risk of toxicity

Calendula officinalis produces gastrointestinal upset in some individuals due to its bitter and pungent properties.

The plant's active compounds, including triterpenoids and sesquiterpenes, can cause stomach irritation, nausea, and diarrhea when ingested.

Additionally, the saponins present in calendula may also contribute to these adverse effects by altering the gut flora and increasing gut permeability.

5. Increases risk of toxicity

Calendula officinalis induces diarrhea suddenly due to its ability to stimulate the digestive system and increase bowel movements.

The plant's high concentration of flavonoids, terpenes, and glycosides can irritate the mucous membranes in the intestines, leading to increased water secretion and rapid transit time, resulting in loose stools or diarrhea.

This reaction is often more pronounced when using calendula as a topical application or ingesting it in large quantities.

6. Increases risk of toxicity

Calendula officinalis increases sensitivity to light.

This side effect is attributed to the plant's ability to stimulate the skin and mucous membranes, which can lead to increased photosensitivity.

The active compounds in Calendula, such as flavonoids and triterpenoids, may enhance the skin's natural response to UV radiation, making it more susceptible to sunburn or other light-induced reactions.

7. Increases risk of toxicity

Calendula officinalis enhances photosensitivity risks.

This is due to its high concentration of flavonoids and carotenoids, which can increase the skin's sensitivity to UV radiation. Additionally, Calendula's anti-inflammatory properties may further exacerbate this effect by reducing the body's natural ability to protect itself against sun damage.

As a result, individuals using Calendula officinalis may be more susceptible to burns, redness, and other phototoxic reactions.

8. Increases risk of toxicity

Calendula officinalis affects blood pressure levels by increasing heart rate and cardiac output due to its stimulatory effects on the cardiovascular system.

This is likely caused by the plant's ability to relax smooth muscle tissue, including that of blood vessels, which can lead to increased peripheral resistance and higher blood pressure.

Additionally, Calendula officinalis may also influence blood pressure through its antioxidant properties, which can help reduce inflammation and improve blood vessel function.

9. Increases risk of toxicity

Calendula officinalis interacts with medications due to its ability to alter liver enzymes and increase their activity.

This can result in an increased risk of toxic levels of certain medications, including sedatives, antidepressants, and blood thinners.

Additionally, Calendula's anti-inflammatory properties may amplify the effects of blood pressure medications, leading to decreased blood pressure and potentially causing symptoms such as dizziness and fatigue.

10. Increases risk of toxicity

Calendula officinalis disrupts hormonal balances due to its potential estrogenic and anti-progesteronic properties.

This can cause issues with women's reproductive health, including irregular menstrual cycles, mood changes, and even a disruption in pregnancy and lactation. The plant contains triterpenoids and flavonoids that may bind to estrogen receptors, leading to an imbalance of hormones in the body.

As a result, individuals using Calendula officinalis may experience unwanted hormonal effects.