hare's-ear

Bupleurum · Accepted scientific name

Scientific literature: Very Sparse (35 studies) · ★☆☆☆☆

hare's-ear, scientifically known as Bupleurum, is a versatile genus of flowering plants within the Apiaceae family. Renowned in traditional medicine, particularly in East Asian practices, its roots are utilized to support liver health, reduce inflammation, and relieve stress. This resilient herb offers significant therapeutic potential for holistic wellness.

Family
Apiaceae
Native range
Europe
Parts used
Root
Common names
Hare'S-Ear · Thoroughwax · 2 more
Scientific synonyms
Isophyllum · Diaphyllum · 13 more

Names and Synonyms

Common Names

Scientific Names

Accepted name

Bupleurum

Synonyms

Regional and Traditional Names

Spanish:

  • Buprestis
  • Bupleureae

German:

  • Hasenohren
  • Hasenohr
  • Hasenohren

French:

  • Buplèvre
  • Buplevre
  • Buplèvres
  • Buplèvre

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and the class Equisetopsida. Within the subclass Magnoliidae, it falls under the order Apiales and the family Apiaceae. Finally, the medicinal species is categorized under the genus Bupleurum.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Apiales
Family Apiaceae
Genus Bupleurum

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a specific distribution pattern across the northern regions of Europe. It can be found growing in the coastal and inland areas of Denmark. Its presence extends further north into the landscapes of Norway and Finland. Additionally, this medicinal species is established within the British Isles, including Great Britain and Ireland. Together, these locations define its primary geographical range in the northern hemisphere.

Region Area
Northern Europe Denmark
Northern Europe Finland
Northern Europe Great Britain
Northern Europe Ireland
Northern Europe Norway
Northern Europe Sweden
Middle Europe Austria
Middle Europe Belgium
Middle Europe Czechia-Slovakia
Middle Europe Germany

Sources: The World Checklist of Vascular Plants (WCVP)

Plant Parts

Bupleurum has 1 reported plant parts identified across 3 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include root.

Plant parts reported in Bupleurum
Plant part Supporting sources Consensus
Root 3 supporting sources ★★☆☆☆

Root

  1. Journal of chromatography
  2. Molecules (Basel, Switzerland)
  3. Journal of pharmaceutical and biomedical analysis

Chemicals

Bupleurum has 11 reported phytochemicals identified across 3 scientific publications and several other databases. The most consistently reported chemicals include Saikosaponins, Lignans, 3''-O-Acetylsaikosaponin d, 6''-O-Acetylsaikosaponin D, 6''-O-acetylsaikosaponin A.

Chemicals reported in Bupleurum
Chemical Supporting sources Consensus
Saikosaponins 3 supporting sources ★★☆☆☆
Lignans 2 supporting sources ★☆☆☆☆
3''-O-Acetylsaikosaponin d 1 supporting sources ★☆☆☆☆
6''-O-Acetylsaikosaponin D 1 supporting sources ★☆☆☆☆
6''-O-acetylsaikosaponin A 1 supporting sources ★☆☆☆☆
Flavonoid 1 supporting sources ★☆☆☆☆
Saikosaponin 1 supporting sources ★☆☆☆☆
Saikosaponin A 1 supporting sources ★☆☆☆☆
Saikosaponin C 1 supporting sources ★☆☆☆☆
Saikosaponin D 1 supporting sources ★☆☆☆☆

Saikosaponins

  1. International journal of molecular sciences
  2. Chinese herbal medicines
  3. The Journal of pharmacy and pharmacology

Lignans

  1. Journal of ethnopharmacology
  2. The Journal of pharmacy and pharmacology

3''-O-Acetylsaikosaponin d

  1. Journal of pharmaceutical and biomedical analysis

6''-O-Acetylsaikosaponin D

  1. Journal of pharmaceutical and biomedical analysis

6''-O-acetylsaikosaponin A

  1. Journal of pharmaceutical and biomedical analysis

Flavonoid

  1. Journal of ethnopharmacology

Saikosaponin

  1. Genes

Saikosaponin A

  1. Yao xue xue bao = Acta pharmaceutica Sinica

Saikosaponin C

  1. Yao xue xue bao = Acta pharmaceutica Sinica

Saikosaponin D

  1. Yao xue xue bao = Acta pharmaceutica Sinica

Activities

Bupleurum has 4 reported activities identified across 3 scientific publications and several other databases. The most consistently reported activities include Hepatoprotective, Antidiabetic, Antimicrobial, Antiviral.

Activities reported in Bupleurum
Activity Supporting sources Consensus
Hepatoprotective 2 supporting sources ★☆☆☆☆
Antidiabetic 1 supporting sources ★☆☆☆☆
Antimicrobial 1 supporting sources ★☆☆☆☆
Antiviral 1 supporting sources ★☆☆☆☆

Hepatoprotective

  1. Journal of ethnopharmacology
  2. The Journal of pharmacy and pharmacology

Antidiabetic

  1. Journal of ethnopharmacology

Antimicrobial

  1. Journal of ethnopharmacology

Antiviral

  1. The Journal of pharmacy and pharmacology

Conditions

Bupleurum has 12 reported investigations on conditions identified across 3 scientific publications and several other databases. The most consistently reported conditions include cancer, diabetes complications, fever, gastric ulcer, infectious diseases.

Conditions investigated for Bupleurum
Condition Supporting sources Consensus
Cancer 1 supporting sources ★☆☆☆☆
Diabetes complications 1 supporting sources ★☆☆☆☆
Fever 1 supporting sources ★☆☆☆☆
Gastric ulcer 1 supporting sources ★☆☆☆☆
Infectious diseases 1 supporting sources ★☆☆☆☆
Inflammation 1 supporting sources ★☆☆☆☆
Irregular menstruation 1 supporting sources ★☆☆☆☆
Liver disease 1 supporting sources ★☆☆☆☆
Pain 1 supporting sources ★☆☆☆☆
Rectal prolapse 1 supporting sources ★☆☆☆☆

Cancer

  1. Journal of ethnopharmacology

Diabetes complications

  1. BMC complementary and alternative medicine

Fever

  1. Journal of ethnopharmacology

Gastric ulcer

  1. Journal of ethnopharmacology

Infectious diseases

  1. The Journal of pharmacy and pharmacology

Inflammation

  1. Journal of ethnopharmacology

Irregular menstruation

  1. Journal of ethnopharmacology

Liver disease

  1. Journal of ethnopharmacology

Pain

  1. Journal of ethnopharmacology

Rectal prolapse

  1. Journal of ethnopharmacology

Preparations

Bupleurum has 5 reported preparations identified across 3 scientific publications and several other databases. The most consistently reported preparations include Bupleuri Radix, KY88, KY88 LIVER LIVO, KY88 Liver Livo, Radix Buplurei.

Preparations reported for Bupleurum
Preparation Supporting sources Consensus
Bupleuri radix 1 supporting sources ★☆☆☆☆
Ky88 1 supporting sources ★☆☆☆☆
Ky88 liver livo 1 supporting sources ★☆☆☆☆
Ky88 liver livo 1 supporting sources ★☆☆☆☆
Radix buplurei 1 supporting sources ★☆☆☆☆

Bupleuri radix

  1. Yao xue xue bao = Acta pharmaceutica Sinica

Ky88

  1. Acta pharmacologica Sinica

Ky88 liver livo

  1. Acta pharmacologica Sinica

Ky88 liver livo

  1. Hong Kong medical journal = Xianggang yi xue za zhi

Radix buplurei

  1. Nan fang yi ke da xue xue bao = Journal of Southern Medical University