Brucea antidysenterica
Brucea antidysenterica · Accepted scientific name
Scientific literature: Very Sparse (35 studies) · ★☆☆☆☆
Brucea antidysenterica, scientifically known as Brucea antidysenterica, is a medicinal plant native to Southeast Asia. Renowned in traditional medicine, its seeds contain potent bioactive compounds used primarily to treat dysentery, amoebiasis, and intestinal infections. This powerful botanical offers significant pharmacological potential for developing modern anti-parasitic treatments.
- Family
- Simaroubaceae
- Native range
- Africa
- Parts used
- Leaf · Stem
- Common names
- Not available
- Scientific synonyms
- Brucea Virginica · Brucea Antidysenterica Var. Crassivenia · 6 more
Names and Synonyms
Scientific Names
Accepted name
Brucea antidysentericaSynonyms
- Brucea virginica
- Brucea antidysenterica var. crassivenia
- Brucea salutaris
- Lussa antidysenterica
- Trichilia siderotricha
- Brucea abyssinica
- Brucea erythraeae
- Brucea ferruginea
Sources: Wikidata
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and the class Equisetopsida. Within the subclass Magnoliidae, it is organized under the order Sapindales and the family Simaroubaceae. Ultimately, its specific taxonomic identity is defined by the genus Brucea.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Sapindales |
| Family | Simaroubaceae |
| Genus | Brucea |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a wide distribution across several regions within the African continent. In West Tropical Africa, it can be found growing in Guinea and Nigeria. Its presence extends into West-Central Tropical Africa, where it is documented in Burundi and the Central African Republic. Additionally, the species is known to inhabit the country of Cameroon. Together, these locations highlight the plant's importance across diverse tropical environments.
| Region | Area |
|---|---|
| West Tropical Africa | Guinea |
| West Tropical Africa | Nigeria |
| West-Central Tropical Africa | Burundi |
| West-Central Tropical Africa | Central African Republic |
| West-Central Tropical Africa | Cameroon |
| West-Central Tropical Africa | Rwanda |
| West-Central Tropical Africa | DR Congo |
| Northeast Tropical Africa | Eritrea |
| Northeast Tropical Africa | Ethiopia |
| Northeast Tropical Africa | Sudan-South Sudan |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Life history
The life history of Brucea antidysenterica is characterized by its status as a perennial species, allowing the plant to persist in its environment over multiple growing seasons. As a long-lived woody plant, it maintains a stable presence within its natural habitat, undergoing continuous developmental cycles that support its long-term survival. This perennial nature ensures that the plant can withstand seasonal fluctuations, repeatedly engaging in vegetative growth and reproductive phases throughout its lifespan.
- Lifecycle :
- perennial
Morphology
The morphology of Brucea antidysenterica is characterized by its growth form, which primarily manifests as a tree or a shrub. As a woody species, it exhibits a robust, self-supporting structure rather than functioning as a climber, liana, or vine. This plant is terrestrial in nature, existing as an independent organism that does not function as an epiphyte or a parasite. In terms of physical stature, it reaches a mean plant height of approximately 7 m, though it can achieve a maximum height of up to 9.144111192 m.
- Aquatic :
- terrestrial
- Climber :
- self-supporting
- Epiphyte :
- terrestrial
- Growth form :
- tree
- Growth form :
- shrub
- Parasite :
- independent
- Plant height max:
- 9.144111192 m
- Plant height mean:
- 7 m
- Woodiness :
- woody
Physiology
The physiology of Brucea antidysenterica is characterized by a standard metabolic framework typical of many woody tropical species. It utilizes the C3 photosynthetic pathway, a mechanism where carbon dioxide is fixed directly through the Calvin cycle using the enzyme RuBisCO, which is efficient under the temperate to subtropical environmental conditions in which it typically grows. Furthermore, the plant does not function as a nitrogen fixer; it lacks the specialized symbiotic relationships with nitrogen-fixing bacteria, such as rhizobia, required to convert atmospheric nitrogen into usable forms, and instead relies on the uptake of nitrates and ammonium from the soil through its root system.
- Nitrogen fixer :
- no
- Photosynthetic pathway :
- C3
Reproduction
The reproduction of Brucea antidysenterica is centered around the production of specialized seeds that facilitate its propagation within its natural habitat. The reproductive cycle culminates in the development of seeds characterized by a highly consistent mass, with a recorded mean seed mass of 0.1 g. This uniformity is reflected in the seed's physical parameters, as both the maximum and minimum recorded seed mass values are 0.1 g, indicating a very narrow range of variation in individual seed weight. This consistency in seed mass suggests a stable investment of resources during the maturation process, ensuring that each seed possesses a standardized amount of nutrient reserves to support early seedling establishment.
- Seed mass mean:
- 0.1 g
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Brucea antidysenterica has 3 reported plant parts identified across 6 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include leaf, stem, seed.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Leaf | 3 supporting sources | ★★☆☆☆ |
| Stem | 2 supporting sources | ★☆☆☆☆ |
| Seed | 1 supporting sources | ★☆☆☆☆ |
Leaf
- BMC complementary medicine and therapies
- Advances in pharmacological and pharmaceutical sciences
- Infection and drug resistance
Stem
- Journal of natural products
- BMC complementary medicine and therapies
Seed
- BMC complementary and alternative medicine
Chemicals
Brucea antidysenterica has 6 reported phytochemicals identified across 6 scientific publications and several other databases. The most consistently reported chemicals include BRUCEANTIN, Bruceanol G, Bruceantinoside C, Flavonoids, Hydnocarpin.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| BRUCEANTIN | 2 supporting sources | ★☆☆☆☆ |
| Bruceanol G | 1 supporting sources | ★☆☆☆☆ |
| Bruceantinoside C | 1 supporting sources | ★☆☆☆☆ |
| Flavonoids | 1 supporting sources | ★☆☆☆☆ |
| Hydnocarpin | 1 supporting sources | ★☆☆☆☆ |
| Phenols | 1 supporting sources | ★☆☆☆☆ |
BRUCEANTIN
- Antimicrobial agents and chemotherapy
- Journal of natural products
Bruceanol G
- Journal of natural products
Bruceantinoside C
- Journal of natural products
Flavonoids
- Advances in pharmacological and pharmaceutical sciences
Hydnocarpin
- BMC complementary medicine and therapies
Phenols
- Advances in pharmacological and pharmaceutical sciences
Activities
Brucea antidysenterica has 5 reported activities identified across 6 scientific publications and several other databases. The most consistently reported activities include Antibacterial, Antimalarial, Antioxidant, Antiproliferative, Cytotoxic.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Antibacterial | 2 supporting sources | ★☆☆☆☆ |
| Antimalarial | 1 supporting sources | ★☆☆☆☆ |
| Antioxidant | 1 supporting sources | ★☆☆☆☆ |
| Antiproliferative | 1 supporting sources | ★☆☆☆☆ |
| Cytotoxic | 1 supporting sources | ★☆☆☆☆ |
Antibacterial
- BMC complementary medicine and therapies
- Infection and drug resistance
Antimalarial
- BMC complementary and alternative medicine
Antioxidant
- Infection and drug resistance
Antiproliferative
- BMC complementary medicine and therapies
Cytotoxic
- Journal of natural products
Conditions
Brucea antidysenterica has 14 reported investigations on conditions identified across 6 scientific publications and several other databases. The most consistently reported conditions include cancer, B16 melanoma, Candida albicans, L1210 leukemia, P388 leukemia.
| Condition | Supporting sources | Consensus |
|---|---|---|
| Cancer | 2 supporting sources | ★☆☆☆☆ |
| B16 melanoma | 1 supporting sources | ★☆☆☆☆ |
| Candida albicans | 1 supporting sources | ★☆☆☆☆ |
| L1210 leukemia | 1 supporting sources | ★☆☆☆☆ |
| P388 leukemia | 1 supporting sources | ★☆☆☆☆ |
| Asthma | 1 supporting sources | ★☆☆☆☆ |
| Diarrhea | 1 supporting sources | ★☆☆☆☆ |
| Dysentery | 1 supporting sources | ★☆☆☆☆ |
| Fever | 1 supporting sources | ★☆☆☆☆ |
| Hematological malignancies | 1 supporting sources | ★☆☆☆☆ |
Cancer
- BMC complementary medicine and therapies
- Journal of natural products
B16 melanoma
- Journal of natural products
Candida albicans
- Advances in pharmacological and pharmaceutical sciences
L1210 leukemia
- Journal of natural products
P388 leukemia
- Journal of natural products
Asthma
- BMC complementary medicine and therapies
Diarrhea
- BMC complementary medicine and therapies
Dysentery
- BMC complementary medicine and therapies
Fever
- BMC complementary medicine and therapies
Hematological malignancies
- Journal of natural products
Preparations
Brucea antidysenterica has 11 reported preparations identified across 6 scientific publications and several other databases. The most consistently reported preparations include 80% Methanol Leaf Extract, 80% methanol leaf extract, BAL, BAS, absolute methanol.
| Preparation | Supporting sources | Consensus |
|---|---|---|
| 80% methanol leaf extract | 1 supporting sources | ★☆☆☆☆ |
| 80% methanol leaf extract | 1 supporting sources | ★☆☆☆☆ |
| Bal | 1 supporting sources | ★☆☆☆☆ |
| Bas | 1 supporting sources | ★☆☆☆☆ |
| Absolute methanol | 1 supporting sources | ★☆☆☆☆ |
| Leaves (bal) extract | 1 supporting sources | ★☆☆☆☆ |
| Methanol extracts | 1 supporting sources | ★☆☆☆☆ |
| Methanol leaf extract | 1 supporting sources | ★☆☆☆☆ |
| Plant extracts | 1 supporting sources | ★☆☆☆☆ |
| Stem (bas) extract | 1 supporting sources | ★☆☆☆☆ |
80% methanol leaf extract
- Infection and drug resistance
80% methanol leaf extract
- Infection and drug resistance
Bal
- BMC complementary medicine and therapies
Bas
- BMC complementary medicine and therapies
Absolute methanol
- Asian Pacific journal of tropical biomedicine
Leaves (bal) extract
- BMC complementary medicine and therapies
Methanol extracts
- BMC complementary medicine and therapies
Methanol leaf extract
- Infection and drug resistance
Plant extracts
- Advances in pharmacological and pharmaceutical sciences
Stem (bas) extract
- BMC complementary medicine and therapies