Bridelia insulana
Bridelia insulana · Accepted scientific name
Scientific literature: Very Sparse (0 studies) · ★☆☆☆☆
Bridelia insulana is a botanical species that has garnered increasing interest for its potential pharmacological properties. In this study, the plant was processed into 50% ethanol-water crude extracts to facilitate the isolation of bioactive compounds. These preparations were subsequently applied to HepG2 cells to evaluate their biological effects on this human liver cancer cell line. By utilizing this specific cellular model, researchers can better understand the extract's interaction with hepatic pathways. This investigation aims to provide foundational insights into the therapeutic potential of Bridelia insulana extracts.
- Synonyms
- Bridelia Subnuda · Bridelia Platyphylla · 9 more
- Common names
- Not available
- Family
- Phyllanthaceae
- Distribution
- Not available
- Plant Parts
- Not available
Classification
Common Names
Bridelia insulana is a distinctive species known by several different names depending on the region. In English-speaking areas, it is commonly referred to as the grey-birch. Meanwhile, in Chinese-speaking communities, the plant is recognized as 禾串樹 or 大葉逼迫子. These diverse monikers reflect the plant's wide geographic presence and cultural importance. Understanding these various names helps botanists and enthusiasts identify the species across different linguistic landscapes.
Sources: Catalogue of Life (COL)
Synonyms
Bridelia insulana is a taxonomically complex species that encompasses several recognized synonyms within its botanical classification. It is closely linked to various forms of Bridelia griffithii, specifically the varieties glabra and penangiana. The plant also includes the distinct variety subnuda under its broader umbrella. Furthermore, researchers have historically identified Bridelia minutiflora as a synonym of this species. This classification extends further to include the specific variety minutiflora var. abbreviata within its related group.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Bridelia insulana is a distinct botanical species that belongs to the vast kingdom Plantae. Within this biological hierarchy, the plant is classified under the class Equisetopsida. It further falls into the order Malpighiales, showcasing its specific evolutionary lineage. This plant is a member of the genus Bridelia, which helps scientists categorize its unique traits. Finally, its taxonomic placement is completed by its membership in the family Phyllanthaceae.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Malpighiales |
| Family | Phyllanthaceae |
| Genus | Bridelia |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Bridelia insulana is a notable species primarily distributed throughout the tropical regions of Asia. Its presence is firmly established across the diverse landscapes of Indo-China, spanning several key nations. Specifically, this plant can be found growing in the territories of Laos, Myanmar, Thailand, and Vietnam. Beyond the mainland, its range extends to the unique ecosystem of the Nicobar Islands. This wide distribution highlights the plant's adaptability to the various tropical environments found across Southeast Asia.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Bridelia insulana is a self-supporting tree that serves as a sturdy component of its native ecosystem. This species typically reaches a maximum height of 18 meters, though it can occasionally grow up to 20 meters under ideal conditions. Its robust growth form allows it to stand firmly without the need for external support. As it matures, the tree provides significant structure to the forest canopy.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Compounds
Conditions
Bridelia insulana exhibits significant anticancer potential when its 50% ethanol-water crude extracts are applied to HepG2 hepatoma cells. During the evaluation of six medicinal herbs, this specific plant demonstrated clear cytotoxicity against the HepG2 cell line. The study utilized neutral red assays to confirm that the extract effectively targets these cancer cells. With IC50 values ranging between 100 and 500 μg/mL for the group of herbs, the extract of Bridelia insulana contributes to the observed inhibitory effects. Ultimately, the research highlights the plant's ability to treat HepG2 cells through these cytotoxic mechanisms.
Preparations
Bridelia insulana is prepared as a 50% ethanol-water crude extract for use in medicinal evaluations. This specific extraction method was utilized as part of a study assessing the anticancer potential of six different herbs. The prepared extract was tested against the HepG2 hepatoma cell line to determine its cytotoxic effects. By using a 50% ethanol-water solution, researchers could analyze the herb's biological activity in a controlled environment. Ultimately, this preparation allowed for the comparison of Bridelia insulana's potency against known substances like melphalan.