Bergera koenigii

Bergera koenigii · Accepted scientific name

Scientific literature: Very Extensive (743 studies) · ★★★★★

, scientifically known as Bergera koenigii, is a versatile medicinal herb renowned in traditional wellness practices. Often valued for its potent bioactive compounds, this plant offers significant therapeutic potential. It is frequently studied for its antioxidant and anti-inflammatory properties, making it a valuable subject in natural pharmacology and herbal medicine.

Family
Rutaceae
Native range
Asia-Temperate
Parts used
Leaf · Root
Common names
Not available
Scientific synonyms
Chalcas Siamensis · Bergera Siamensis · 6 more

Names and Synonyms

Scientific Names

Accepted name

Bergera koenigii

Synonyms

Sources: Wikidata

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Sapindales, it is classified under the family Rutaceae. Finally, its specific taxonomic designation is placed within the genus Bergera.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Sapindales
Family Rutaceae
Genus Bergera

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a widespread distribution across several specific regions in Asia. Within China, it can be found throughout the South-Central provinces and the Southeast region. Additionally, its presence is documented on the tropical island of Hainan. Moving to the Indian Subcontinent, the species is known to grow in the state of Assam. Finally, its geographical range extends further into the country of Bangladesh.

Region Area
China China South-Central
China Hainan
China China Southeast
Indian Subcontinent Assam
Indian Subcontinent Bangladesh
Indian Subcontinent East Himalaya
Indian Subcontinent India
Indian Subcontinent Laccadive Is.
Indian Subcontinent Maldives
Indian Subcontinent Nepal

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Ecology

The ecology of Bergera koeinigii is characterized by its ability to inhabit a broad vertical gradient across diverse montane and sub-montane landscapes. This species demonstrates significant adaptability to varying topographical conditions, occupying an expansive elevational range that extends from as low as 150 m AMSL to elevations reaching as high as 2900 m AMSL. This wide altitudinal distribution suggests that the plant can tolerate a diverse array of climatic variables, including fluctuations in temperature, humidity, and atmospheric pressure associated with shifting mountain profiles. Such a broad ecological niche allows it to persist in both lowland tropical or subtropical environments and higher-altitude regions where environmental stressors are more pronounced.

Elevational range max:
2900 m AMSL
Elevational range min:
150 m AMSL

Life history

The life history of Bergera koeinigii is characterized by its status as a perennial plant, allowing it to persist through multiple growing seasons rather than completing its cycle in a single year. Throughout its lifespan, the plant maintains an evergreen nature, retaining its foliage continuously rather than shedding it seasonally. This combination of a long-lived lifecycle and constant leaf presence enables the species to maintain a stable biological presence within its ecological niche.

Deciduousness :
evergreen
Lifecycle :
perennial

Morphology

The morphology of Bergera koeinigii is characterized by its growth form as a woody tree, reaching a mean plant height of approximately 6 m. This species functions as an independent organism, meaning it does not exhibit parasitic behavior, and it is categorized as a terrestrial plant rather than an aquatic, semiaquatic, or epiphytic species. In terms of its structural habit, the plant is self-supporting, functioning neither as an obligatory nor a facultative climber, such as a liana or vine, but rather maintaining its own stature through its woody composition.

Aquatic :
terrestrial
Climber :
self-supporting
Epiphyte :
terrestrial
Growth form :
tree
Parasite :
independent
Plant height mean:
6 m
Woodiness :
woody

Physiology

The physiology of Bergia koenigii is characterized by a C3 photosynthetic pathway, which dictates its carbon fixation process and metabolic efficiency within its natural habitat. In terms of nutrient acquisition, the plant does not function as a nitrogen fixer, meaning it relies on the uptake of available nitrogen from the soil through its root system rather than through symbiotic relationships with nitrogen-fixing bacteria.

Nitrogen fixer :
no
Photosynthetic pathway :
C3

Reproduction

The reproduction of Bergera koenigii is characterized by a specific flowering phenology that governs its seasonal reproductive cycle. The plant begins its flowering period in April, marking the onset of its reproductive phase. This flowering duration continues through the warmer and more stable months, eventually reaching its conclusion in October. While the timing of these reproductive events can be subject to environmental variations, the core cycle typically spans from the spring months through the autumn, ensuring a window of opportunity for pollination and subsequent seed development.

Flowering time :
Apr
Flowering time :
Oct

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Bergera koenigii has 4 reported plant parts identified across 38 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include leaf, root, stem, seed.

Plant parts reported in Bergera koenigii
Plant part Supporting sources Consensus
Leaf 31 supporting sources ★★★★★
Root 4 supporting sources ★★☆☆☆
Stem 2 supporting sources ★☆☆☆☆
Seed 1 supporting sources ★☆☆☆☆

Leaf

  1. Investigational new drugs
  2. Applied biochemistry and biotechnology
  3. Phytotherapy research : PTR
  4. Bioscience, biotechnology, and biochemistry
  5. Scientific reports
View 26 additional sources
  1. Journal of parasitic diseases : official organ of the Indian Society for Parasitology
  2. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  3. Journal of natural products
  4. Journal of ethnopharmacology
  5. Journal of agricultural and food chemistry
  6. Biomedical chromatography : BMC
  7. Clinical therapeutics
  8. BioMed research international
  9. Veterinary world
  10. Antioxidants (Basel, Switzerland)
  11. Luminescence : the journal of biological and chemical luminescence
  12. Molecules (Basel, Switzerland)
  13. Cureus
  14. Journal of tropical medicine
  15. Plants (Basel, Switzerland)
  16. Biological trace element research
  17. Brazilian journal of biology = Revista brasleira de biologia
  18. ACS omega
  19. Biotechnology and applied biochemistry
  20. Drug development and industrial pharmacy
  21. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie
  22. Food & function
  23. Heliyon
  24. Folia microbiologica
  25. Evidence-based complementary and alternative medicine : eCAM
  26. Archives of physiology and biochemistry

Root

  1. Bioscience, biotechnology, and biochemistry
  2. Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]
  3. Antioxidants (Basel, Switzerland)
  4. Folia microbiologica

Stem

  1. Biotechnology and applied biochemistry
  2. Folia microbiologica

Seed

  1. Fitoterapia

Chemicals

Bergera koenigii has 185 reported phytochemicals identified across 38 scientific publications and several other databases. The most consistently reported chemicals include Mahanimbine, Mahanine, Girinimbine, Flavonoids, Koenimbine.

Chemicals reported in Bergera koenigii
Chemical Supporting sources Consensus
Mahanimbine 10 supporting sources ★★★★★
Mahanine 9 supporting sources ★★★★☆
Girinimbine 8 supporting sources ★★★★☆
Flavonoids 4 supporting sources ★★☆☆☆
Koenimbine 4 supporting sources ★★☆☆☆
Ash 3 supporting sources ★★☆☆☆
Flavonoid 3 supporting sources ★★☆☆☆
Koenigine 3 supporting sources ★★☆☆☆
Koenine 3 supporting sources ★★☆☆☆
O-Methylmurrayamine A 3 supporting sources ★★☆☆☆

Mahanimbine

  1. Dr. Duke
  2. Phytotherapy research : PTR
  3. Journal of agricultural and food chemistry
  4. Chemistry & biodiversity
  5. Biomedical chromatography : BMC
View 5 additional sources
  1. BioMed research international
  2. Journal of ethnopharmacology
  3. Molecules (Basel, Switzerland)
  4. Journal of natural products
  5. Journal of Asian natural products research

Mahanine

  1. Dr. Duke
  2. Scientific reports
  3. Journal of agricultural and food chemistry
  4. Phytomedicine : international journal of phytotherapy and phytopharmacology
  5. Chemistry & biodiversity
View 4 additional sources
  1. Biomedical chromatography : BMC
  2. BioMed research international
  3. Journal of ethnopharmacology
  4. Pharmacological research

Girinimbine

  1. Dr. Duke
  2. Applied biochemistry and biotechnology
  3. Bioscience, biotechnology, and biochemistry
  4. Chemistry & biodiversity
  5. Cellular and molecular biology (Noisy-le-Grand, France)
View 3 additional sources
  1. Journal of ethnopharmacology
  2. Journal of Asian natural products research
  3. Food & function

Flavonoids

  1. Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]
  2. Pakistan journal of pharmaceutical sciences
  3. Journal of ethnopharmacology
  4. Biotechnology and applied biochemistry

Koenimbine

  1. Dr. Duke
  2. Chemistry & biodiversity
  3. ACS omega
  4. Journal of Asian natural products research

Ash

  1. Dr. Duke
  2. Pakistan journal of pharmaceutical sciences
  3. Heliyon

Flavonoid

  1. Journal of acupuncture and meridian studies
  2. Veterinary world
  3. Asian Pacific journal of tropical medicine

Koenigine

  1. Dr. Duke
  2. Chemistry & biodiversity
  3. Journal of natural products

Koenine

  1. Dr. Duke
  2. Applied biochemistry and biotechnology
  3. Journal of ethnopharmacology

O-Methylmurrayamine A

  1. Applied biochemistry and biotechnology
  2. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  3. Chemistry & biodiversity

Activities

Bergera koenigii has 387 reported activities identified across 38 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Antimicrobial, Antidiabetic, Antibacterial, Anticancer.

Activities reported in Bergera koenigii
Activity Supporting sources Consensus
Antioxidant 15 supporting sources ★★★★★
Antimicrobial 7 supporting sources ★★★★☆
Antidiabetic 5 supporting sources ★★★☆☆
Antibacterial 4 supporting sources ★★☆☆☆
Anticancer 4 supporting sources ★★☆☆☆
Antitumor 4 supporting sources ★★☆☆☆
Cytotoxic 4 supporting sources ★★☆☆☆
Antiviral 3 supporting sources ★★☆☆☆
Hypoglycemic 3 supporting sources ★★☆☆☆
Antiinflammatory 2 supporting sources ★☆☆☆☆

Antioxidant

  1. Dr. Duke
  2. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine
  3. BioMed research international
  4. Journal of agricultural and food chemistry
  5. Journal of acupuncture and meridian studies
View 10 additional sources
  1. Biomedical chromatography : BMC
  2. Antioxidants (Basel, Switzerland)
  3. Cardiovascular & hematological agents in medicinal chemistry
  4. Journal of ethnopharmacology
  5. Luminescence : the journal of biological and chemical luminescence
  6. Pharmacological research
  7. Biotechnology and applied biochemistry
  8. Current pharmaceutical design
  9. Food & function
  10. Heliyon

Antimicrobial

  1. Journal of agricultural and food chemistry
  2. Journal of acupuncture and meridian studies
  3. Antioxidants (Basel, Switzerland)
  4. Luminescence : the journal of biological and chemical luminescence
  5. Biotechnology and applied biochemistry
View 2 additional sources
  1. Current pharmaceutical design
  2. Heliyon

Antidiabetic

  1. Dr. Duke
  2. Antioxidants (Basel, Switzerland)
  3. Luminescence : the journal of biological and chemical luminescence
  4. Pharmacological research
  5. Heliyon

Antibacterial

  1. Dr. Duke
  2. Biomedical chromatography : BMC
  3. Luminescence : the journal of biological and chemical luminescence
  4. Heliyon

Anticancer

  1. Dr. Duke
  2. Scientific reports
  3. Biomedical chromatography : BMC
  4. Molecules (Basel, Switzerland)

Antitumor

  1. Dr. Duke
  2. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine
  3. Antioxidants (Basel, Switzerland)
  4. Pharmacological research

Cytotoxic

  1. Dr. Duke
  2. Journal of acupuncture and meridian studies
  3. Luminescence : the journal of biological and chemical luminescence
  4. Biotechnology and applied biochemistry

Antiviral

  1. Dr. Duke
  2. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine
  3. Pharmacological research

Hypoglycemic

  1. Dr. Duke
  2. Biomedical chromatography : BMC
  3. Journal of alternative and complementary medicine (New York, N.Y.)

Antiinflammatory

  1. Dr. Duke
  2. Journal of agricultural and food chemistry

Conditions

Bergera koenigii has 1 reported investigations on conditions identified across 38 scientific publications and several other databases. The most consistently reported conditions include cancer stem cells.

Conditions investigated for Bergera koenigii
Condition Supporting sources Consensus
Cancer stem cells 1 supporting sources ★☆☆☆☆

Cancer stem cells

  1. Bioscience, biotechnology, and biochemistry

Preparations

Bergera koenigii has 27 reported preparations identified across 38 scientific publications and several other databases. The most consistently reported preparations include leaves, Leaf extracts, MK leaf and stem whole extracts obtained using toluene, Mk leaf extract, acetone extract of the fresh leaves of Murraya koenigii.

Preparations reported for Bergera koenigii
Preparation Supporting sources Consensus
Leaves 2 supporting sources ★☆☆☆☆
Leaf extracts 1 supporting sources ★☆☆☆☆
Mk leaf and stem whole extracts obtained using toluene 1 supporting sources ★☆☆☆☆
Mk leaf extract 1 supporting sources ★☆☆☆☆
Acetone extract of the fresh leaves of murraya koenigii 1 supporting sources ★☆☆☆☆
Aqueous and ethanolic fractions 1 supporting sources ★☆☆☆☆
Aqueous extract 1 supporting sources ★☆☆☆☆
Aqueous leaf extract 1 supporting sources ★☆☆☆☆
Aqueous leaves extract 1 supporting sources ★☆☆☆☆
Callus cultures 1 supporting sources ★☆☆☆☆

Leaves

  1. ACS omega
  2. Journal of parasitic diseases : official organ of the Indian Society for Parasitology

Leaf extracts

  1. Cureus

Mk leaf and stem whole extracts obtained using toluene

  1. Biotechnology and applied biochemistry

Mk leaf extract

  1. Drug development and industrial pharmacy

Acetone extract of the fresh leaves of murraya koenigii

  1. Journal of agricultural and food chemistry

Aqueous and ethanolic fractions

  1. Antioxidants (Basel, Switzerland)

Aqueous extract

  1. Journal of ethnopharmacology

Aqueous leaf extract

  1. Luminescence : the journal of biological and chemical luminescence

Aqueous leaves extract

  1. Journal of ethnopharmacology

Callus cultures

  1. Bioscience, biotechnology, and biochemistry