Oregon-grape
Berberis · Accepted scientific name
Scientific literature: Moderate (125 studies) · ★★★☆☆
Oregon-grape, scientifically known as Berberis, is a versatile shrub prized for its medicinal properties. Renowned for its bright yellow roots and berries, it contains berberine, a potent alkaloid. Traditionally used to support digestive health, regulate blood sugar, and combat inflammation, this resilient plant remains a cornerstone of herbal medicine.
Names and Synonyms
Common Names
- Oregon-grape
- barberry
- Barberries
- holly grape
Scientific Names
Accepted name
BerberisSynonyms
- Alloberberis
- × Mahoberberis
- Odostemon
- Mahonia
- Moranothamnus
Regional and Traditional Names
Spanish:
- Agracillo
- Acetin
- Acetín
- Coralitis
- Arlera
- Cetinera
- Alguese
- Arlo
- Agracejo
- Agracejo
German:
- Berberitzen
- Berberitze
- Berberitzen
French:
- Berbéris
- Épines-vinettes et mahonias
- Berbéris
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. It is further classified within the order Ranunculales and the family Berberidaceae. Finally, its specific taxonomic designation is within the genus Berberis.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Ranunculales |
| Family | Berberidaceae |
| Genus | Berberis |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a specific distribution pattern across several regions of Northern Europe. It can be found growing in the natural landscapes of Denmark. The species is also documented throughout the territory of Finland. Additionally, its presence extends to the islands of Great Britain and Ireland. Finally, the geographical range includes the rugged terrains of Norway.
| Region | Area |
|---|---|
| Northern Europe | Denmark |
| Northern Europe | Finland |
| Northern Europe | Great Britain |
| Northern Europe | Ireland |
| Northern Europe | Norway |
| Northern Europe | Sweden |
| Middle Europe | Austria |
| Middle Europe | Belgium |
| Middle Europe | Czechia-Slovakia |
| Middle Europe | Germany |
Sources: The World Checklist of Vascular Plants (WCVP)
Plant Parts
Berberis has 4 reported plant parts identified across 13 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include root, stem, leaf, fruit.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Root | 6 supporting sources | ★★★☆☆ |
| Stem | 4 supporting sources | ★★☆☆☆ |
| Leaf | 2 supporting sources | ★☆☆☆☆ |
| Fruit | 1 supporting sources | ★☆☆☆☆ |
Root
- Journal of ethnopharmacology
- 3 Biotech
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Scientific reports
- Journal of proteome research
View 1 additional sources
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Stem
- 3 Biotech
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Journal of proteome research
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Leaf
- 3 Biotech
- Journal of proteome research
Fruit
- Molecules (Basel, Switzerland)
Chemicals
Berberis has 13 reported phytochemicals identified across 13 scientific publications and several other databases. The most consistently reported chemicals include berberine, BERBAMINE, Jatrorrhizine, Palmatine, 5'-Methoxyhydnocarpin-D.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| berberine | 8 supporting sources | ★★★★☆ |
| BERBAMINE | 5 supporting sources | ★★★☆☆ |
| Jatrorrhizine | 4 supporting sources | ★★☆☆☆ |
| Palmatine | 4 supporting sources | ★★☆☆☆ |
| 5'-Methoxyhydnocarpin-D | 1 supporting sources | ★☆☆☆☆ |
| 5'-methoxyhydnocarpin | 1 supporting sources | ★☆☆☆☆ |
| Capsanthin | 1 supporting sources | ★☆☆☆☆ |
| Coptisine | 1 supporting sources | ★☆☆☆☆ |
| Flavonoids | 1 supporting sources | ★☆☆☆☆ |
| Sterols | 1 supporting sources | ★☆☆☆☆ |
berberine
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Pharmacological research
- Biomedicines
- Metabolites
- Pharmaceutica acta Helvetiae
View 3 additional sources
- Journal of proteome research
- Biotechnology and applied biochemistry
- Proceedings of the National Academy of Sciences of the United States of America
BERBAMINE
- Current topics in medicinal chemistry
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Journal of ethnopharmacology
- Pharmacognosy reviews
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Jatrorrhizine
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Pharmaceutica acta Helvetiae
- Journal of proteome research
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Palmatine
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Pharmaceutica acta Helvetiae
- Journal of proteome research
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
5'-Methoxyhydnocarpin-D
- Journal of molecular microbiology and biotechnology
5'-methoxyhydnocarpin
- Proceedings of the National Academy of Sciences of the United States of America
Capsanthin
- Current drug research reviews
Coptisine
- Cytotechnology
Flavonoids
- PloS one
Sterols
- Pharmacognosy reviews
Activities
Berberis has 16 reported activities identified across 13 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Antimicrobial, Antinociceptive, Antipyretic, Hepatoprotective.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Antioxidant | 5 supporting sources | ★★★☆☆ |
| Antimicrobial | 4 supporting sources | ★★☆☆☆ |
| Antinociceptive | 2 supporting sources | ★☆☆☆☆ |
| Antipyretic | 2 supporting sources | ★☆☆☆☆ |
| Hepatoprotective | 2 supporting sources | ★☆☆☆☆ |
| Analgesic | 1 supporting sources | ★☆☆☆☆ |
| Antiemetic | 1 supporting sources | ★☆☆☆☆ |
| Antihypertensive | 1 supporting sources | ★☆☆☆☆ |
| Antiinflammatory | 1 supporting sources | ★☆☆☆☆ |
| Antimalarial | 1 supporting sources | ★☆☆☆☆ |
Antioxidant
- Current topics in medicinal chemistry
- Journal of ethnopharmacology
- Pharmacological research
- Behavioural pharmacology
- Pharmacognosy reviews
Antimicrobial
- Journal of ethnopharmacology
- International journal of molecular sciences
- Pharmacognosy reviews
- Proceedings of the National Academy of Sciences of the United States of America
Antinociceptive
- Life sciences
- Behavioural pharmacology
Antipyretic
- Life sciences
- Pharmacognosy reviews
Hepatoprotective
- Journal of ethnopharmacology
- Combinatorial chemistry & high throughput screening
Analgesic
- Journal of ethnopharmacology
Antiemetic
- Pharmacognosy reviews
Antihypertensive
- Phytotherapy research : PTR
Antiinflammatory
- Combinatorial chemistry & high throughput screening
Antimalarial
- Current topics in medicinal chemistry
Medicinal Uses
Berberis has 28 reported medicinal uses identified across 13 scientific publications and several other databases. The most consistently reported uses include cancer, neurodegenerative disorders, seizures, HPV infection, Parkinson's disease.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| cancer | Current drug targets (and other 3 sources) | ★★☆☆☆ |
| neurodegenerative disorders | Iranian journal of basic medical sciences (and other 2 sources) | ★☆☆☆☆ |
| seizures | Iranian journal of basic medical sciences (and other 2 sources) | ★☆☆☆☆ |
| HPV infection | Molecular cancer (and other 1 sources) | ★☆☆☆☆ |
| Parkinson's disease | PloS one (and other 1 sources) | ★☆☆☆☆ |
| adenocarcinoma | Scientific reports (and other 1 sources) | ★☆☆☆☆ |
| amoebiasis | Evidence-based complementary and alternative medicine : eCAM (and other 1 sources) | ★☆☆☆☆ |
| anti-arrhythmic | Pharmacognosy reviews (and other 1 sources) | ★☆☆☆☆ |
| anti-cholinergic | Pharmacognosy reviews (and other 1 sources) | ★☆☆☆☆ |
| antiemetic | Pharmacognosy reviews (and other 1 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| herbal extract | PloS one (and other 1 sources) | ★☆☆☆☆ |
| methanol extracts | Journal of analytical methods in chemistry (and other 1 sources) | ★☆☆☆☆ |
| methanolic extracts from bark and core of root and stem | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials (and other 1 sources) | ★☆☆☆☆ |
| tea tree oil | American journal of clinical dermatology (and other 1 sources) | ★☆☆☆☆ |