Oregon-grape

Berberis · Accepted scientific name

Scientific literature: Moderate (125 studies) · ★★★☆☆

Oregon-grape, scientifically known as Berberis, is a versatile shrub prized for its medicinal properties. Renowned for its bright yellow roots and berries, it contains berberine, a potent alkaloid. Traditionally used to support digestive health, regulate blood sugar, and combat inflammation, this resilient plant remains a cornerstone of herbal medicine.

Family
Berberidaceae
Native range
Europe
Parts used
Root · Stem
Common names
Oregon-Grape · Barberry · 2 more
Scientific synonyms
Alloberberis · × Mahoberberis · 3 more

Names and Synonyms

Common Names

Scientific Names

Accepted name

Berberis

Synonyms

Regional and Traditional Names

Spanish:

  • Agracillo
  • Acetin
  • Acetín
  • Coralitis
  • Arlera
  • Cetinera
  • Alguese
  • Arlo
  • Agracejo
  • Agracejo

German:

  • Berberitzen
  • Berberitze
  • Berberitzen

French:

  • Berbéris
  • Épines-vinettes et mahonias
  • Berbéris

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. It is further classified within the order Ranunculales and the family Berberidaceae. Finally, its specific taxonomic designation is within the genus Berberis.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Ranunculales
Family Berberidaceae
Genus Berberis

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a specific distribution pattern across several regions of Northern Europe. It can be found growing in the natural landscapes of Denmark. The species is also documented throughout the territory of Finland. Additionally, its presence extends to the islands of Great Britain and Ireland. Finally, the geographical range includes the rugged terrains of Norway.

Region Area
Northern Europe Denmark
Northern Europe Finland
Northern Europe Great Britain
Northern Europe Ireland
Northern Europe Norway
Northern Europe Sweden
Middle Europe Austria
Middle Europe Belgium
Middle Europe Czechia-Slovakia
Middle Europe Germany

Sources: The World Checklist of Vascular Plants (WCVP)

Plant Parts

Berberis has 4 reported plant parts identified across 13 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include root, stem, leaf, fruit.

Plant parts reported in Berberis
Plant part Supporting sources Consensus
Root 6 supporting sources ★★★☆☆
Stem 4 supporting sources ★★☆☆☆
Leaf 2 supporting sources ★☆☆☆☆
Fruit 1 supporting sources ★☆☆☆☆

Root

  1. Journal of ethnopharmacology
  2. 3 Biotech
  3. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  4. Scientific reports
  5. Journal of proteome research
View 1 additional sources
  1. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

Stem

  1. 3 Biotech
  2. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  3. Journal of proteome research
  4. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

Leaf

  1. 3 Biotech
  2. Journal of proteome research

Fruit

  1. Molecules (Basel, Switzerland)

Chemicals

Berberis has 13 reported phytochemicals identified across 13 scientific publications and several other databases. The most consistently reported chemicals include berberine, BERBAMINE, Jatrorrhizine, Palmatine, 5'-Methoxyhydnocarpin-D.

Chemicals reported in Berberis
Chemical Supporting sources Consensus
berberine 8 supporting sources ★★★★☆
BERBAMINE 5 supporting sources ★★★☆☆
Jatrorrhizine 4 supporting sources ★★☆☆☆
Palmatine 4 supporting sources ★★☆☆☆
5'-Methoxyhydnocarpin-D 1 supporting sources ★☆☆☆☆
5'-methoxyhydnocarpin 1 supporting sources ★☆☆☆☆
Capsanthin 1 supporting sources ★☆☆☆☆
Coptisine 1 supporting sources ★☆☆☆☆
Flavonoids 1 supporting sources ★☆☆☆☆
Sterols 1 supporting sources ★☆☆☆☆

berberine

  1. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  2. Pharmacological research
  3. Biomedicines
  4. Metabolites
  5. Pharmaceutica acta Helvetiae
View 3 additional sources
  1. Journal of proteome research
  2. Biotechnology and applied biochemistry
  3. Proceedings of the National Academy of Sciences of the United States of America

BERBAMINE

  1. Current topics in medicinal chemistry
  2. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  3. Journal of ethnopharmacology
  4. Pharmacognosy reviews
  5. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

Jatrorrhizine

  1. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  2. Pharmaceutica acta Helvetiae
  3. Journal of proteome research
  4. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

Palmatine

  1. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  2. Pharmaceutica acta Helvetiae
  3. Journal of proteome research
  4. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

5'-Methoxyhydnocarpin-D

  1. Journal of molecular microbiology and biotechnology

5'-methoxyhydnocarpin

  1. Proceedings of the National Academy of Sciences of the United States of America

Capsanthin

  1. Current drug research reviews

Coptisine

  1. Cytotechnology

Flavonoids

  1. PloS one

Sterols

  1. Pharmacognosy reviews

Activities

Berberis has 16 reported activities identified across 13 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Antimicrobial, Antinociceptive, Antipyretic, Hepatoprotective.

Activities reported in Berberis
Activity Supporting sources Consensus
Antioxidant 5 supporting sources ★★★☆☆
Antimicrobial 4 supporting sources ★★☆☆☆
Antinociceptive 2 supporting sources ★☆☆☆☆
Antipyretic 2 supporting sources ★☆☆☆☆
Hepatoprotective 2 supporting sources ★☆☆☆☆
Analgesic 1 supporting sources ★☆☆☆☆
Antiemetic 1 supporting sources ★☆☆☆☆
Antihypertensive 1 supporting sources ★☆☆☆☆
Antiinflammatory 1 supporting sources ★☆☆☆☆
Antimalarial 1 supporting sources ★☆☆☆☆

Antioxidant

  1. Current topics in medicinal chemistry
  2. Journal of ethnopharmacology
  3. Pharmacological research
  4. Behavioural pharmacology
  5. Pharmacognosy reviews

Antimicrobial

  1. Journal of ethnopharmacology
  2. International journal of molecular sciences
  3. Pharmacognosy reviews
  4. Proceedings of the National Academy of Sciences of the United States of America

Antinociceptive

  1. Life sciences
  2. Behavioural pharmacology

Antipyretic

  1. Life sciences
  2. Pharmacognosy reviews

Hepatoprotective

  1. Journal of ethnopharmacology
  2. Combinatorial chemistry & high throughput screening

Analgesic

  1. Journal of ethnopharmacology

Antiemetic

  1. Pharmacognosy reviews

Antihypertensive

  1. Phytotherapy research : PTR

Antiinflammatory

  1. Combinatorial chemistry & high throughput screening

Antimalarial

  1. Current topics in medicinal chemistry

Conditions

Berberis has 28 reported investigations on conditions identified across 13 scientific publications and several other databases. The most consistently reported conditions include cancer, neurodegenerative disorders, seizures, HPV infection, Parkinson's disease.

Conditions investigated for Berberis
Condition Supporting sources Consensus
Cancer 3 supporting sources ★★☆☆☆
Neurodegenerative disorders 2 supporting sources ★☆☆☆☆
Seizures 2 supporting sources ★☆☆☆☆
Hpv infection 1 supporting sources ★☆☆☆☆
Parkinson's disease 1 supporting sources ★☆☆☆☆
Adenocarcinoma 1 supporting sources ★☆☆☆☆
Amoebiasis 1 supporting sources ★☆☆☆☆
Anti-arrhythmic 1 supporting sources ★☆☆☆☆
Anti-cholinergic 1 supporting sources ★☆☆☆☆
Antiemetic 1 supporting sources ★☆☆☆☆

Cancer

  1. Current drug targets
  2. Phytomedicine : international journal of phytotherapy and phytopharmacology
  3. Scientific reports

Neurodegenerative disorders

  1. Iranian journal of basic medical sciences
  2. Phytomedicine : international journal of phytotherapy and phytopharmacology

Seizures

  1. Iranian journal of basic medical sciences
  2. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Hpv infection

  1. Molecular cancer

Parkinson's disease

  1. PloS one

Adenocarcinoma

  1. Scientific reports

Amoebiasis

  1. Evidence-based complementary and alternative medicine : eCAM

Anti-arrhythmic

  1. Pharmacognosy reviews

Anti-cholinergic

  1. Pharmacognosy reviews

Antiemetic

  1. Pharmacognosy reviews

Preparations

Berberis has 4 reported preparations identified across 13 scientific publications and several other databases. The most consistently reported preparations include herbal extract, methanol extracts, methanolic extracts from bark and core of root and stem, tea tree oil.

Preparations reported for Berberis
Preparation Supporting sources Consensus
Herbal extract 1 supporting sources ★☆☆☆☆
Methanol extracts 1 supporting sources ★☆☆☆☆
Methanolic extracts from bark and core of root and stem 1 supporting sources ★☆☆☆☆
Tea tree oil 1 supporting sources ★☆☆☆☆

Herbal extract

  1. PloS one

Methanol extracts

  1. Journal of analytical methods in chemistry

Methanolic extracts from bark and core of root and stem

  1. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

Tea tree oil

  1. American journal of clinical dermatology