common barberry

Berberis vulgaris · Accepted scientific name

Scientific literature: Very Extensive (974 studies) · ★★★★★

Common barberry, scientifically known as Berberis vulgaris, is a deciduous shrub celebrated for its medicinal properties. Renowned for containing berberine, it offers potent anti-inflammatory and antimicrobial benefits. Historically used to treat digestive issues and skin conditions, this resilient plant remains a cornerstone in traditional herbal medicine and wellness practices.

Family
Berberidaceae
Native range
Europe
Parts used
Leaf · Root
Common names
European Barberry · Common Barberry · 4 more
Scientific synonyms
Not available

Names and Synonyms

Common Names

Scientific Names

Accepted name

Berberis vulgaris

Regional and Traditional Names

Spanish:

  • Berberis vulgaris subsp cantabrica
  • Berberis vulgaris subsp hispanica
  • Berberis australis
  • Berberis vulgaris L subsp vulgaris
  • Berberis vulgaris subsp australis
  • abrilla
  • acetín
  • agracejo
  • agracejo oficinal
  • agracillo
  • agracillos
  • agracio
  • agraciu
  • agranzón
  • agrazón
  • agreilla
  • agrito
  • agruzejo
  • alargiz
  • alarguez
  • alarguiz
  • alguese
  • alrera
  • alro
  • arlera
  • arlo
  • aspalato
  • azota-Cristos
  • azote burdo
  • berberiles
  • berbero
  • berberís
  • borrachín
  • bérberis
  • bérbero
  • bérberoles
  • bérberos
  • escabrión
  • espina ramosa
  • espina romaza
  • espino
  • espino berberino
  • espino cambrón
  • garbanzón
  • granado
  • guindillas ásperas
  • tapaculo
  • vinagrera
  • vinagreras
  • agracejo
  • espino cambrón
  • abrilla
  • acetín
  • agracejo oficinal
  • agracillo
  • agracillos
  • agracio
  • agraciu
  • agranzón
  • agrazón
  • agreilla
  • agrito
  • agruzejo
  • alargiz
  • alarguez
  • alarguiz
  • alguese
  • alrera
  • alro
  • arlera
  • arlo
  • aspalato
  • azota-Cristos
  • azote burdo
  • berberiles
  • berbero
  • berberís
  • borrachín
  • bérbero
  • bérberoles
  • bérberos
  • escabrión
  • espina ramosa
  • espina romaza
  • espino
  • espino berberino
  • garbanzón
  • granado
  • guindillas ásperas
  • tapaculo
  • vinagrera
  • vinagreras

German:

  • Berberitze
  • Gewöhnliche Berberitze
  • Echte Berberitze
  • Gemeiner Sauerdorn
  • Sauerdorn
  • Essigbeere
  • epine-vinette
  • Gemeine Berberitze
  • Basselbeere
  • Beiselbeere
  • Dreidorn
  • Erbsal
  • Erbselbeerstrauch
  • Erbseldorn
  • Erbselholz
  • Erbsich
  • Essigdorn
  • Essigscharf
  • Geißenlaub
  • Hasenbrot
  • Kuckucksbrot
  • Peisselbeere
  • Spießdorn
  • Spitzdorn
  • Weinäuglein
  • Weinlegelein
  • Weinscheidling
  • Weinzäpferl
  • Zitronenbeere
  • Berberitze
  • Sauerdorn
  • Gewöhnliche Berberitze
  • Gemeine Berberitze
  • Echte Berberitze
  • Essigbeere
  • Gemeiner Sauerdorn

French:

  • Épine-vinette
  • Épine vinette
  • Epine-Vinette
  • Épine-vinette vulgaire
  • berbéride vulgaire
  • berbéris vulgaire
  • épine-vinette
  • épine-vinette commune
  • vinettier
  • Epine-vinette
  • Berbéris commun
  • Vinettier commun
  • Épine vinette
  • Épine-vinette vulgaire

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae within the phylum Streptophyta and is classified under the class Equisetopsida. As a member of the subclass Magnoliidae and the order Ranunculales, it is further categorized into the family Berberidaceae. Finally, it is identified by its specific genus, Berberis.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Ranunculales
Family Berberidaceae
Genus Berberis

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant, known as Berberis vulgaris, is widely distributed across several regions in Northern Europe. It can be found growing naturally throughout the landscapes of Denmark. Additionally, this medicinal species is present within the territories of Finland and Norway. The plant also establishes itself across the islands of Great Britain and Ireland. Consequently, its geographical range covers a significant portion of the northernmost European continent.

Region Area
Northern Europe Denmark
Northern Europe Finland
Northern Europe Great Britain
Northern Europe Ireland
Northern Europe Norway
Northern Europe Sweden
Middle Europe Austria
Middle Europe Belgium
Middle Europe Czechia-Slovakia
Middle Europe Germany

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Ecology

The ecology of Berberis vulgaris is characterized by its adaptability to diverse temperate environments, often thriving in open woodlands, scrublands, and forest edges where it can access sufficient sunlight. It typically occupies a wide elevational range, demonstrating a significant capacity to inhabit varying altitudes across its native and naturalized territories. The species exhibits a mean elevation of 1518 m AMSL, reflecting its ability to persist in both lowland valleys and mid-to-high altitude montane zones. In these habitats, it plays a functional role in the ecosystem by providing nectar for pollinators and berries for avian dispersal, while its thorny structure offers protective nesting sites for various fauna. The plant is well-suited to various soil types, often preferring well-drained, acidic to neutral substrates, and it can tolerate a range of climatic conditions including cold winters and moderate seasonal variations.

Elevational range mean:
1518 m AMSL

Life history

The life history of Berberis vulgaris is characterized by its classification as a perennial plant, allowing it to persist through multiple growing seasons. As a phanerophyte, its buds are borne on aerial shoots well above the ground, a structural trait that defines its growth habit. This species follows a deciduous life cycle, meaning it sheds its leaves annually in response to seasonal changes, typically entering a period of dormancy during the winter months. This combination of perennial longevity, a phanerophyte life form, and deciduous foliage dictates its rhythmic patterns of seasonal growth, flowering, and nutrient conservation.

Deciduousness :
deciduous
Life form :
phanerophyte
Lifecycle :
perennial

Morphology

The morphology of Berberis vulgaris is characterized by a woody growth form, specifically classified as a shrub. As a terrestrial organism, it grows independently and is not an epiphyte or a parasite. The plant is self-supporting rather than acting as a climber or liana. In terms of stature, it exhibits significant variation in height, ranging from a minimum of 1 m to a maximum of 4 m, with an average plant height of approximately 1.917 m.

Aquatic :
terrestrial
Climber :
self-supporting
Epiphyte :
terrestrial
Growth form :
shrub
Parasite :
independent
Plant height max:
4 m
Plant height mean:
1.917 m
Plant height min:
1 m
Woodiness :
woody

Physiology

The physiology of Berberis vulgaris is characterized by a C3 photosynthetic pathway, which governs its carbon fixation processes and metabolic efficiency. As a non-carnivorous species, the plant relies entirely on autotrophic nutrition through soil-based nutrient uptake rather than capturing prey. Its leaf morphology exhibits specific dimensions, with leaf lengths ranging from a minimum of 1 cm to a maximum of 2.5 cm, supporting an average leaf size of approximately 2.77933 cm². Furthermore, the plant displays a mean Specific Leaf Area (SLA) of 130.32 cm²/g, a physiological metric that reflects the relationship between its leaf area and its dry mass, indicating its strategy for light interception and resource allocation.

Carnivory :
non-carnivorous
Leaf length max:
2.5 cm
Leaf length min:
1 cm
Leaf size mean:
2.77933 cm²
Photosynthetic pathway :
C3
Specific Leaf Area (SLA) mean:
130.32 cm²/g

Reproduction

The reproduction of Berberis vulgaris is driven by sexual processes, as asexual reproduction is notably absent. The flowering period typically commences in May and concludes in June. The plant utilizes a biotic pollination syndrome, specifically relying on insects, with bees serving as a primary pollinator. While self-fertilization is present within the species, the reproductive cycle is heavily supported by these animal vectors. Following successful pollination, the plant develops fleshy, indehiscent fruits classified as berries. These fruits possess an average length of 0.99 cm and an average width of 0.55 cm. The dispersal of the species follows a zoochorous syndrome, meaning seeds are dispersed by animals. The seeds themselves are characterized by a mean mass of approximately 0.0256695334 g (with a range between 0.0099 g and 0.02366 g) and a consistent seed volume of 20 mm³.

Dehiscence :
indehiscent
Dispersal syndrome :
zoochorous
Flowering time :
May
Flowering time :
Jun
Fruit dryness :
fleshy
Fruit length mean:
0.99 cm
Fruit type :
berry
Fruit width mean:
0.55 cm
Pollination syndrome :
insect
Pollination syndrome :
bee
Pollination syndrome :
biotic
Reproduction asexual :
absent
Seed mass max:
0.02366 g
Seed mass mean:
0.0256695334 g
Seed mass min:
0.0099 g
Seed volume max:
20 mm³
Self fertilization :
present

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Berberis vulgaris has 5 reported plant parts identified across 20 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include leaf, root, fruit, stem, flower.

Plant parts reported in Berberis vulgaris
Plant part Supporting sources Consensus
Leaf 6 supporting sources ★★★☆☆
Root 6 supporting sources ★★★☆☆
Fruit 5 supporting sources ★★★☆☆
Stem 2 supporting sources ★☆☆☆☆
Flower 1 supporting sources ★☆☆☆☆

Leaf

  1. Life (Basel, Switzerland)
  2. Clinical and experimental dental research
  3. Chemistry & biodiversity
  4. Pakistan journal of pharmaceutical sciences
  5. Journal of education and health promotion
View 1 additional sources
  1. Avicenna journal of phytomedicine

Root

  1. Phytotherapy research : PTR
  2. Iranian journal of psychiatry
  3. International journal of molecular sciences
  4. Pakistan journal of pharmaceutical sciences
  5. Nutrients
View 1 additional sources
  1. International journal of immunopharmacology

Fruit

  1. Antioxidants (Basel, Switzerland)
  2. Cell biochemistry and function
  3. Molecules (Basel, Switzerland)
  4. Clinical and experimental dental research
  5. Pakistan journal of pharmaceutical sciences

Stem

  1. Clinical and experimental dental research
  2. Pakistan journal of pharmaceutical sciences

Flower

  1. Journal of ethnobiology and ethnomedicine

Chemicals

Berberis vulgaris has 91 reported phytochemicals identified across 20 scientific publications and several other databases. The most consistently reported chemicals include berberine, Flavonoids, BERBAMINE, CHLOROGENIC ACID, Jatrorrhizine.

Chemicals reported in Berberis vulgaris
Chemical Supporting sources Consensus
berberine 11 supporting sources ★★★★★
Flavonoids 5 supporting sources ★★★☆☆
BERBAMINE 3 supporting sources ★★☆☆☆
CHLOROGENIC ACID 3 supporting sources ★★☆☆☆
Jatrorrhizine 3 supporting sources ★★☆☆☆
Magnoflorine 3 supporting sources ★★☆☆☆
Palmatine 3 supporting sources ★★☆☆☆
Tannin 3 supporting sources ★★☆☆☆
citric acid 3 supporting sources ★★☆☆☆
malic acid 3 supporting sources ★★☆☆☆

berberine

  1. Dr. Duke
  2. Current neuropharmacology
  3. Current pharmaceutical biotechnology
  4. Endocrine, metabolic & immune disorders drug targets
  5. Alternative medicine review : a journal of clinical therapeutic
View 6 additional sources
  1. Journal of separation science
  2. Journal of diabetes and metabolic disorders
  3. IUBMB life
  4. Phytotherapy research : PTR
  5. Iranian journal of basic medical sciences
  6. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

Flavonoids

  1. Scientific reports
  2. Phytochemical analysis : PCA
  3. Molecules (Basel, Switzerland)
  4. Acta poloniae pharmaceutica
  5. Avicenna journal of phytomedicine

BERBAMINE

  1. Dr. Duke
  2. Phytotherapy research : PTR
  3. Avicenna journal of phytomedicine

CHLOROGENIC ACID

  1. Dr. Duke
  2. Molecules (Basel, Switzerland)
  3. Phytochemical analysis : PCA

Jatrorrhizine

  1. Dr. Duke
  2. Journal of separation science
  3. Avicenna journal of phytomedicine

Magnoflorine

  1. Dr. Duke
  2. International journal of molecular sciences
  3. Nutrients

Palmatine

  1. Dr. Duke
  2. Journal of separation science
  3. Avicenna journal of phytomedicine

Tannin

  1. Dr. Duke
  2. Molecules (Basel, Switzerland)
  3. Avicenna journal of phytomedicine

citric acid

  1. Dr. Duke
  2. Molecules (Basel, Switzerland)
  3. Avicenna journal of phytomedicine

malic acid

  1. Dr. Duke
  2. Molecules (Basel, Switzerland)
  3. Avicenna journal of phytomedicine

Activities

Berberis vulgaris has 644 reported activities identified across 20 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Hepatoprotective, Antibacterial, Anticancer, Antidepressant.

Activities reported in Berberis vulgaris
Activity Supporting sources Consensus
Antioxidant 9 supporting sources ★★★★☆
Hepatoprotective 4 supporting sources ★★☆☆☆
Antibacterial 3 supporting sources ★★☆☆☆
Anticancer 3 supporting sources ★★☆☆☆
Antidepressant 3 supporting sources ★★☆☆☆
Antidiabetic 3 supporting sources ★★☆☆☆
Hypoglycemic 3 supporting sources ★★☆☆☆
Hypolipidemic 3 supporting sources ★★☆☆☆
Analgesic 2 supporting sources ★☆☆☆☆
Anticoagulant 2 supporting sources ★☆☆☆☆

Antioxidant

  1. Dr. Duke
  2. Molecules (Basel, Switzerland)
  3. Current pharmaceutical biotechnology
  4. EXCLI journal
  5. Nanomaterials (Basel, Switzerland)
View 4 additional sources
  1. Iranian journal of basic medical sciences
  2. Molecular biology reports
  3. Phytotherapy research : PTR
  4. Avicenna journal of phytomedicine

Hepatoprotective

  1. Dr. Duke
  2. Current pharmaceutical biotechnology
  3. Scientific reports
  4. Journal of education and health promotion

Antibacterial

  1. Dr. Duke
  2. IUBMB life
  3. Iranian journal of basic medical sciences

Anticancer

  1. Dr. Duke
  2. Scientific reports
  3. Phytotherapy research : PTR

Antidepressant

  1. Dr. Duke
  2. Current pharmaceutical biotechnology
  3. Iranian journal of basic medical sciences

Antidiabetic

  1. Dr. Duke
  2. IUBMB life
  3. Iranian journal of basic medical sciences

Hypoglycemic

  1. Dr. Duke
  2. Current pharmaceutical biotechnology
  3. Avicenna journal of phytomedicine

Hypolipidemic

  1. Dr. Duke
  2. Current pharmaceutical biotechnology
  3. IUBMB life

Analgesic

  1. Dr. Duke
  2. Iranian journal of basic medical sciences

Anticoagulant

  1. Dr. Duke
  2. Evidence-based complementary and alternative medicine : eCAM

Conditions

Berberis vulgaris has 52 reported investigations on conditions identified across 20 scientific publications and several other databases. The most consistently reported conditions include cancer, oxidative stress, Alzheimer's disease, antioxidant, gastric ulcer.

Conditions investigated for Berberis vulgaris
Condition Supporting sources Consensus
Cancer 3 supporting sources ★★☆☆☆
Oxidative stress 3 supporting sources ★★☆☆☆
Alzheimer's disease 2 supporting sources ★☆☆☆☆
Antioxidant 2 supporting sources ★☆☆☆☆
Gastric ulcer 2 supporting sources ★☆☆☆☆
Hypoglycemic 2 supporting sources ★☆☆☆☆
Inflammation 2 supporting sources ★☆☆☆☆
Metabolic syndrome 2 supporting sources ★☆☆☆☆
Obesity 2 supporting sources ★☆☆☆☆
Cholera 1 supporting sources ★☆☆☆☆

Cancer

  1. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
  2. IUBMB life
  3. Iranian journal of basic medical sciences

Oxidative stress

  1. EXCLI journal
  2. Phytotherapy research : PTR
  3. Iranian journal of basic medical sciences

Alzheimer's disease

  1. Pharmacological research
  2. Medicina (Kaunas, Lithuania)

Antioxidant

  1. Current pharmaceutical biotechnology
  2. Phytotherapy research : PTR

Gastric ulcer

  1. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  2. Pakistan journal of pharmaceutical sciences

Hypoglycemic

  1. Current pharmaceutical biotechnology
  2. Avicenna journal of phytomedicine

Inflammation

  1. Iranian journal of basic medical sciences
  2. Phytotherapy research : PTR

Metabolic syndrome

  1. International journal of nanomedicine
  2. Iranian journal of psychiatry

Obesity

  1. Phytotherapy research : PTR
  2. Avicenna journal of phytomedicine

Cholera

  1. Scientific reports

Preparations

Berberis vulgaris has 19 reported preparations identified across 20 scientific publications and several other databases. The most consistently reported preparations include methanolic extract, Alcoholic extracts, Jujube syrup, Urinil B, aqueous plant extracts.

Preparations reported for Berberis vulgaris
Preparation Supporting sources Consensus
Methanolic extract 2 supporting sources ★☆☆☆☆
Alcoholic extracts 1 supporting sources ★☆☆☆☆
Jujube syrup 1 supporting sources ★☆☆☆☆
Urinil b 1 supporting sources ★☆☆☆☆
Aqueous plant extracts 1 supporting sources ★☆☆☆☆
Barberry extract 1 supporting sources ★☆☆☆☆
Barberry fruit extract 1 supporting sources ★☆☆☆☆
Berbermin 1 supporting sources ★☆☆☆☆
Berberrubine 1 supporting sources ★☆☆☆☆
Botanicals 1 supporting sources ★☆☆☆☆

Methanolic extract

  1. Molecules (Basel, Switzerland)
  2. International journal of molecular sciences

Alcoholic extracts

  1. Journal of pharmaceutical and biomedical analysis

Jujube syrup

  1. Dermatologic therapy

Urinil b

  1. Pakistan journal of pharmaceutical sciences

Aqueous plant extracts

  1. Nanomaterials (Basel, Switzerland)

Barberry extract

  1. Antioxidants (Basel, Switzerland)

Barberry fruit extract

  1. Cell biochemistry and function

Berbermin

  1. International journal of immunopharmacology

Berberrubine

  1. Biomedical reports

Botanicals

  1. Journal of alternative and complementary medicine (New York, N.Y.)