Berberis aquifolium

Berberis aquifolium · Accepted scientific name

Scientific literature: Very Extensive (299 studies) · ★★★★★

, scientifically known as Berberis aquifolium, is a prominent medicinal shrub native to the Himalayan region. Widely utilized in Ayurvedic medicine, its roots and bark contain potent alkaloids like berberine. These properties offer significant therapeutic benefits, particularly for treating digestive disorders, skin ailments, and inflammatory conditions effectively.

Family
Berberidaceae
Native range
Europe
Parts used
Stem · Root
Common names
Not available
Scientific synonyms
Mahonia Brevipes · Mahonia Aquifolium · 23 more

Names

Scientific Names

Accepted name

Berberis aquifolium

Synonyms

Taxonomical Classification

This plant belongs to the kingdom Plantae and falls under the phylum Streptophyta within the class Equisetopsida. It is further classified under the subclass Magnoliidae and the order Ranunculales. Finally, it is a member of the family Berberidaceae, situated within the genus Berberis.

Rank Classification Source
Kingdom Plantae WCVP
Phylum Streptophyta WCVP
Class Equisetopsida WCVP
Subclass Magnoliidae WCVP
Order Ranunculales WCVP
Family Berberidaceae WCVP
Genus Berberis WCVP

Distribution

This plant exhibits a specific geographical distribution concentrated within the regions of Northern Europe. Its presence can be documented across several Scandinavian nations, including Denmark, Norway, and Sweden. Furthermore, it is found in the northern territories of Finland. The species also extends its range westward to include Great Britain. Together, these locations define the primary northern habitats where the plant thrives.

Region Area Source
Northern Europe Denmark WCVP
Northern Europe Finland WCVP
Northern Europe Great Britain WCVP
Northern Europe Norway WCVP
Northern Europe Sweden WCVP
Middle Europe Austria WCVP
Middle Europe Belgium WCVP
Middle Europe Czechia-Slovakia WCVP
Middle Europe Germany WCVP
Middle Europe Hungary WCVP

Plant Parts

This plant, Berberis aquifolium, is valued in traditional medicine for the various therapeutic properties found within its anatomical structures. The woody stems provide the structural framework for the shrub, while the thick stem bark serves as a primary source of alkaloids like berberine. Whether used in its whole form or processed as concentrated stem-bark preparations, these components are vital for medicinal efficacy. Additionally, the roots are frequently harvested for their potent bioactive compounds, and the various extracts derived from these different parts are often utilized in pharmacological applications to treat diverse ailments.
Plant Part Sources Consensus
stem Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti (and other 3 sources) ★★☆☆☆
root Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆

Chemicals

Berberis aquifolium has 31 reported phytochemicals identified across 4 scientific publications and several other databases. The most consistently reported chemicals include berberine, BERBAMINE, Corytuberine, Jatrorrhizine, Magnoflorine.

Chemicals reported in Berberis aquifolium
Chemical Supporting sources Consensus
berberine 5 supporting sources ★★★☆☆
BERBAMINE 3 supporting sources ★★☆☆☆
Corytuberine 3 supporting sources ★★☆☆☆
Jatrorrhizine 3 supporting sources ★★☆☆☆
Magnoflorine 3 supporting sources ★★☆☆☆
Oxyacanthine 3 supporting sources ★★☆☆☆
Aquifoline 2 supporting sources ★☆☆☆☆
Baluchistine 2 supporting sources ★☆☆☆☆
Columbamine 2 supporting sources ★☆☆☆☆
Obamegine 2 supporting sources ★☆☆☆☆

berberine

  1. Dr. Duke
  2. Planta medica
  3. Alternative medicine review : a journal of clinical therapeutic
  4. Journal of separation science
  5. IUBMB life

BERBAMINE

  1. Dr. Duke
  2. Planta medica
  3. Die Pharmazie

Corytuberine

  1. Dr. Duke
  2. Planta medica
  3. Methods and findings in experimental and clinical pharmacology

Jatrorrhizine

  1. Dr. Duke
  2. Planta medica
  3. Journal of separation science

Magnoflorine

  1. Dr. Duke
  2. Planta medica
  3. Methods and findings in experimental and clinical pharmacology

Oxyacanthine

  1. Dr. Duke
  2. Planta medica
  3. Die Pharmazie

Aquifoline

  1. Dr. Duke
  2. Die Pharmazie

Baluchistine

  1. Dr. Duke
  2. Die Pharmazie

Columbamine

  1. Dr. Duke
  2. Planta medica

Obamegine

  1. Dr. Duke
  2. Die Pharmazie

Activities

Berberis aquifolium has 190 reported activities identified across 4 scientific publications and several other databases. The most consistently reported activities include Antibacterial, Antihypertensive, Fungicide, (+)-Inotropic, Abortifacient.

Most Reported Activities

Activity Sources Consensus
Antibacterial Dr. Duke (and other 3 sources) ★★☆☆☆
Antihypertensive Dr. Duke (and other 2 sources) ★☆☆☆☆
Fungicide Dr. Duke (and other 2 sources) ★☆☆☆☆
(+)-Inotropic Dr. Duke (and other 1 sources) ★☆☆☆☆
Abortifacient Dr. Duke (and other 1 sources) ★☆☆☆☆
Adrenocorticotrophic Dr. Duke (and other 1 sources) ★☆☆☆☆
Adrenolytic Dr. Duke (and other 1 sources) ★☆☆☆☆
Amebicide Dr. Duke (and other 1 sources) ★☆☆☆☆
Analeptic Dr. Duke (and other 1 sources) ★☆☆☆☆
Analgesic Dr. Duke (and other 1 sources) ★☆☆☆☆

Medicinal Uses

Berberis aquifolium has 3 reported medicinal uses identified across 4 scientific publications and several other databases. The most consistently reported uses include Wounds and injuries, abscesses, cancer.

Most Reported Uses

Use Sources Consensus
Wounds and injuries Journal of ethnobiology and ethnomedicine (and other 1 sources) ★☆☆☆☆
abscesses Journal of ethnobiology and ethnomedicine (and other 1 sources) ★☆☆☆☆
cancer IUBMB life (and other 1 sources) ★☆☆☆☆

Preparations

Preparations Sources Consensus
Mahonia aquifolium extracts Die Pharmazie (and other 2 sources) ★☆☆☆☆
extracts The British journal of dermatology (and other 2 sources) ★☆☆☆☆
Crude extracts obtained from the stem bark Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti (and other 1 sources) ★☆☆☆☆
M. aquifolium extracts Planta medica (and other 1 sources) ★☆☆☆☆
Mahonia aquifolium ointment Forschende Komplementarmedizin (and other 1 sources) ★☆☆☆☆
Mahonia aquifolium stem-bark Journal of pharmaceutical and biomedical analysis (and other 1 sources) ★☆☆☆☆
extract of the bark of Mahonia aquifolium Planta medica (and other 1 sources) ★☆☆☆☆
roots Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
stems Fitoterapia (and other 1 sources) ★☆☆☆☆