soulvine

Banisteriopsis caapi · Accepted scientific name

Scientific literature: Moderate (103 studies) · ★★★☆☆

Soulvine, scientifically known as Banisteriopsis caapi, is a legendary woody vine central to Amazonian shamanic traditions. Often called the "vine of the soul," it serves as the essential primary ingredient in ayahuasca brews. Renowned for its potent psychoactive properties, it is revered for inducing profound spiritual and healing experiences.

Family
Malpighiaceae
Native range
Southern America
Parts used
Stem · Leaf
Common names
Soulvine · Mariri
Scientific synonyms
Banisteriopsis Quitensis · Banisteria Inebrians · 3 more

Names

Common Names

Regional and Traditional Names

Spanish:

  • Natema
  • Banisteriopsis quitensis
  • Banisteriopsis inebrians
  • Yajé
  • Banisteria inebrians
  • Yaje
  • Bejuco de oro
  • Banisteria caapi
  • Yage
  • Yagé
  • Banisteria quitensis

German:

  • Banisteria caapi

Scientific Names

Accepted name

Banisteriopsis caapi

Synonyms

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta. Within the class Equisetopsida and subclass Magnoliidae, it is classified under the order Malpighiales and the family Malpighiaceae. Finally, its taxonomic identity is completed within the genus Banisteriopsis.

Rank Classification Source
Kingdom Plantae WCVP
Phylum Streptophyta WCVP
Class Equisetopsida WCVP
Subclass Magnoliidae WCVP
Order Malpighiales WCVP
Family Malpighiaceae WCVP
Genus Banisteriopsis WCVP

Distribution

This plant is primarily found across the diverse landscapes of Northern and Western South America. In the northern region, its presence is specifically noted within the borders of Venezuela. Moving toward the western part of the continent, the species maintains a significant distribution throughout Colombia and Ecuador. It is also widely documented across the expansive territories of Peru. Finally, the geographical range extends further south into the western reaches of Bolivia.

Region Area Source
Northern South America Venezuela WCVP
Western South America Bolivia WCVP
Western South America Colombia WCVP
Western South America Ecuador WCVP
Western South America Peru WCVP
Brazil Brazil West-Central WCVP
Brazil Brazil North WCVP
Southern South America Argentina Northwest WCVP

Plant Parts

This plant, Banisteriopsis caapi, is primarily characterized by its woody climbing vine structure, which serves as the essential source for its medicinal properties. To prepare traditional decoctions, practitioners often harvest the bark or the stem bark, as these layers contain the highest concentration of harmala alkaloids. Depending on the specific preparation method and the age of the specimen, healers may utilize the whole matured stem to ensure a potent extraction, or they may collect substantial portions of the stems/large branches to accommodate larger ceremonial quantities.
Plant Part Sources Consensus
stem Journal of ethnopharmacology (and other 2 sources) ★☆☆☆☆
leaf Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
root Revista de neurologia (and other 1 sources) ★☆☆☆☆

Chemicals

Banisteriopsis caapi has 17 reported phytochemicals identified across 4 scientific publications and several other databases. The most consistently reported chemicals include HARMINE, Tetrahydroharmine, harmaline, Harmol, N,N-DIMETHYLTRYPTAMINE.

Chemicals reported in Banisteriopsis caapi
Chemical Supporting sources Consensus
HARMINE 6 supporting sources ★★★☆☆
Tetrahydroharmine 6 supporting sources ★★★☆☆
harmaline 5 supporting sources ★★★☆☆
Harmol 2 supporting sources ★☆☆☆☆
N,N-DIMETHYLTRYPTAMINE 2 supporting sources ★☆☆☆☆
5-Hydroxy-N,N-dimethyltryptamine 1 supporting sources ★☆☆☆☆
5-Methoxy-N,N-dimethyltryptamine 1 supporting sources ★☆☆☆☆
Dihydroshihunine 1 supporting sources ★☆☆☆☆
Epicatechin 1 supporting sources ★☆☆☆☆
Harmalinic acid 1 supporting sources ★☆☆☆☆

HARMINE

  1. ACS omega
  2. Journal of ethnopharmacology
  3. Pharmaceuticals (Basel, Switzerland)
  4. Frontiers in pharmacology
  5. Drug and alcohol dependence
View 1 additional sources
  1. Scientific reports

Tetrahydroharmine

  1. Dr. Duke
  2. ACS omega
  3. Journal of ethnopharmacology
  4. Pharmaceuticals (Basel, Switzerland)
  5. Biomedical chromatography : BMC
View 1 additional sources
  1. Scientific reports

harmaline

  1. Dr. Duke
  2. ACS omega
  3. Journal of ethnopharmacology
  4. Pharmaceuticals (Basel, Switzerland)
  5. Scientific reports

Harmol

  1. ACS omega
  2. Scientific reports

N,N-DIMETHYLTRYPTAMINE

  1. Dr. Duke
  2. ACS omega

5-Hydroxy-N,N-dimethyltryptamine

  1. Dr. Duke

5-Methoxy-N,N-dimethyltryptamine

  1. Dr. Duke

Dihydroshihunine

  1. Dr. Duke

Epicatechin

  1. Journal of ethnopharmacology

Harmalinic acid

  1. Dr. Duke

Activities

Banisteriopsis caapi has 30 reported activities identified across 4 scientific publications and several other databases. The most consistently reported activities include Psychoactive, Psychotropic, Anthelmintic, Antibacterial, Antifeedant.

Most Reported Activities

Activity Sources Consensus
Psychoactive Journal of ethnopharmacology (and other 4 sources) ★★☆☆☆
Psychotropic Dr. Duke (and other 2 sources) ★☆☆☆☆
Anthelmintic Dr. Duke (and other 1 sources) ★☆☆☆☆
Antibacterial Dr. Duke (and other 1 sources) ★☆☆☆☆
Antifeedant Dr. Duke (and other 1 sources) ★☆☆☆☆
Antileishmanic Dr. Duke (and other 1 sources) ★☆☆☆☆
Antimalarial Dr. Duke (and other 1 sources) ★☆☆☆☆
Antimitotic Dr. Duke (and other 1 sources) ★☆☆☆☆
Antiparkinsonian Dr. Duke (and other 1 sources) ★☆☆☆☆
Antitrypanosomic Dr. Duke (and other 1 sources) ★☆☆☆☆

Medicinal Uses

Banisteriopsis caapi has 11 reported medicinal uses identified across 4 scientific publications and several other databases. The most consistently reported uses include Alzheimer's disease, Parkinson's disease, addictive behaviors, anxiety, anxiety disorders.

Most Reported Uses

Use Sources Consensus
Alzheimer's disease Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
Parkinson's disease Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
addictive behaviors Journal of psychoactive drugs (and other 1 sources) ★☆☆☆☆
anxiety Pharmaceuticals (Basel, Switzerland) (and other 1 sources) ★☆☆☆☆
anxiety disorders CNS drugs (and other 1 sources) ★☆☆☆☆
bacterial infections Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
brain disorders Scientific reports (and other 1 sources) ★☆☆☆☆
depression Pharmaceuticals (Basel, Switzerland) (and other 1 sources) ★☆☆☆☆
neurodegenerative disorders Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
neurological disorders Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆

Preparations

Preparations Sources Consensus
tea Case reports in emergency medicine (and other 3 sources) ★★☆☆☆
Ayahuasca Life sciences (and other 2 sources) ★☆☆☆☆
ayahuasca Journal of ethnopharmacology (and other 2 sources) ★☆☆☆☆
Amazonian ayahuasca brew Frontiers in pharmacology (and other 1 sources) ★☆☆☆☆
Infusions of ayahuasca Revista de neurologia (and other 1 sources) ★☆☆☆☆
admixture Journal of psychoactive drugs (and other 1 sources) ★☆☆☆☆
aqueous concoction Pharmaceuticals (Basel, Switzerland) (and other 1 sources) ★☆☆☆☆
aqueous extract Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
aqueous extracts Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
beta-carbonyls PloS one (and other 1 sources) ★☆☆☆☆