Atractylodes koreana

What's the taxonomical classification of Atractylodes koreana?

Atractylodes koreana belongs to the kingdom Plantae and is classified under the phylum Streptophyta. Within the class Equisetopsida, it is further categorized under the subclass Magnoliidae. The plant follows the taxonomic order Asterales and is a member of the family Asteraceae. Specifically, it is situated within the genus Atractylodes, with its precise scientific designation being the species koreana.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Asterales
Family Asteraceae
Genus Atractylodes
Species koreana
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Atractylodes koreana has a perennial rhizomatous habit characterized by thick, fleshy underground stems and large, deeply lobed leaves that emerge from a basal rosette. The foliage consists of large, ovate to cordate leaves with serrated margins and distinctively deep, pinnatifid divisions. During its flowering stage, the plant produces terminal capitula that are composed of numerous small, tubular florets arranged in a dense head. These flower heads are typically surrounded by involucral bracts that exhibit a characteristic texture and shape unique to the species. The overall structure is robust, supporting a tall stem that elevates the inflorescence above the ground-level foliage.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is endemic to the Korean Peninsula, where it is primarily found in the mountainous regions of South Korea. It grows in specific habitats such as forest margins and shaded slopes at mid-to-high elevations. The species is typically distributed across various provinces, often favoring cool and temperate climates. Its occurrence is relatively localized compared to more widespread medicinal herbs. These specific environmental requirements limit its natural range to these particular Korean highland ecosystems.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant requires well-drained, fertile soil with a pH between 5.5 and 6.5 and a location that receives full sun to partial shade.

Cultivation begins by planting rhizomes in the spring to ensure adequate establishment before the winter dormancy period. Regular watering is necessary during the growing season to maintain consistent moisture without causing waterlogging. Maintaining organic matter through the addition of compost helps support the vigorous development of its root system.

Careful monitoring for soil compaction and proper drainage is essential to prevent fungal diseases in the cultivated beds.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

This plant Atractylodes koreanas medicinal properties are derived specifically from its underground rhizome. This tuberous root structure contains concentrated volatile oils and sesquiterpenoids that provide therapeutic benefits. Practitioners typically harvest and dry these rhizomes to prepare various decoctions or powders. These extracts are traditionally utilized in herbal medicine to support digestive health and reduce inflammation. The chemical potency found within the rhizome makes it the primary focus for pharmaceutical applications of this species.

According to a study published by "Journal of separation science", the rhizome of Atractylodes koreana is the part used for essential oil extraction via hydrodistillation. This study analyzed 20 samples of Atractylodes lancea and Atractylodes koreana to assess quality through gas chromatography with flame ionization detection. The extraction yields for the samples ranged from 1.33% to 4.06%. Researchers quantified 5 volatile components in the essential oils to validate their multivariate statistical analysis. These volatile components include atractylon, atractydin, and atractylenolide I, II, and III.

The parts of this plant that are ued medicinally are shown in the list below.

  • rhizome
Evidence Level: ★★★☆☆

What traditional systems uses this plant?

This plant Atractylodes koreanas has been utilized for centuries in Traditional Chinese Medicine and Kampo to treat various digestive ailments and regulate bodily fluids. Practitioners historically employed its pungent and warm properties to strengthen the spleen and stomach systems. In these traditional frameworks, it is frequently prescribed to alleviate abdominal pain, bloating, and diarrhea caused by dampness. The root is often combined with other herbs to restore harmony to the digestive tract and reduce edema. Through these long-standing medical traditions, the species has established a reputation as a vital component in managing gastrointestinal health.

According to a study published by "Journal of separation science", Atractylodes rhizome is a valuable traditional Chinese medicinal herb. The essential oils of Atractylodes koreana were extracted by hydrodistillation, resulting in an average yield of 2.42%. Through the use of gas chromatography with mass spectrometry, 45 volatile components were identified in A. koreana. The major component found in the essential oil of A. koreana was eudesma-4(14)-en-11-ol at 11.81%. These findings demonstrate that the essential oils of this species differ in content and composition.

The hystorical systems that uses this plant are shown in the list below.

  • Traditional Chinese Medicine
  • Kampo
Evidence Level: ★★★☆☆

What are the pharmacological activities of Atractylodes koreana?

This plant has significant anti-inflammatory, antioxidant, anti-tumor, and anti-diabetic pharmacological activities. Its bioactive compounds work to suppress inflammatory cytokines and reduce oxidative stress within cellular environments. Research indicates that specific extracts can inhibit the growth of various cancer cell lines by inducing apoptosis. Additionally, the plant demonstrates potential in regulating blood glucose levels, making it a subject of interest for metabolic studies. These diverse biological effects suggest its high therapeutic potential for treating chronic inflammatory and metabolic diseases.

Evidence Level: ★☆☆☆☆

What medicinal compounds this plant contains?

This plant contains the medicinal compounds atractydiin, atractylenolide I, atractylenolide II, atractylenolide III, and atractylon. These specific sesquiterpene lactones are the primary bioactive constituents responsible for its pharmacological properties. Research indicates that these compounds contribute significantly to the plant's anti-inflammatory and analgesic effects. Atractylenolides are particularly noted for their ability to modulate various biological pathways in the body. The presence of these diverse chemical structures makes the species a valuable subject for pharmaceutical study.

According to a study published by "Journal of separation science", the essential oils of Atractylodes koreana were extracted from samples via hydrodistillation. These essential oils contain volatile components including atractylon, atractydin, and atractylenolid I, II, and III. The study quantified 5 volatile components within these essential oils to validate multivariate statistical analysis. While extraction yields for the studied samples ranged from 1.33-4.06%, the specific number and content of these volatile components differed for Atractylodes koreana. This quantitative analysis provides a foundation for the quality control of the plant.

The primary medicinal compounds of this plant are shown in the list below.

  • atractydiin
  • atractylenolid I
  • atractylenolid II
  • atractylenolid III
  • atractylon
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for treating digestive disorders, reducing inflammation, improving liver function, and managing blood sugar levels in diabetic patients. Its medicinal properties are primarily attributed to its ability to stimulate gastric secretions and enhance intestinal motility. Researchers have also noted its potential in protecting the liver from oxidative stress and toxin-induced damage. Additionally, the bioactive compounds within the root help suppress inflammatory responses in various bodily tissues. These diverse therapeutic applications make it a significant component in traditional herbal medicine.

Evidence Level: ★☆☆☆☆

What are the herbal preparations of this plant?

This plant is used to create medicinal herbal preparations such as Cangzhu, So-jutsu, and various essential oils. Cangzhu is prepared from the dried rhizome and is primarily utilized in traditional medicine to dispel dampness and relieve pain. In contrast, So-jutsu is made from the processed rhizome to focus its therapeutic effects on warming the middle burner and drying moisture. These preparations are often integrated into complex formulas to address digestive ailments and inflammatory conditions. Furthermore, the essential oils extracted from the plant serve as concentrated components for both aromatic and topical applications.

According to a study published by "Mitochondrial DNA. Part B, Resources", Atractylodes koreana (Nakai) Kitam is a perennial herb of Asteraceae mainly distributed in China and Korea that serves as the main adulterant of the traditional herbal medicine 'Cangzhu'. The complete chloroplast genome of Atractylodes koreana has a total length of 153,232 bp and consists of four regions. These regions include one large single copy (LSC) region of 84,250 bp, one small single copy (SSC) region of 18,690 bp, and two inverted repeat regions (IRa and IRb) of 25,146 bp each. The GC content of this complete cp genome is 37.7%. A total of 110 unique genes were annotated, which comprise 79 protein-coding genes, 27 transfer RNA (tRNA) genes, and four ribosome RNA (rRNA) genes. Among these, nine protein-coding genes contained one intron and three protein-coding genes, specifically clpP, ycf3, and rps12, contained two introns.

The main herbal preparations of this plant are shown in the list below.

  • Cangzhu
  • So-jutsu
  • Essential oils
Evidence Level: ★★★☆☆

What side effects this plant can have?

This plant can cause nausea, digestive upset, and dizziness in individuals who consume it. These adverse reactions typically occur when the plant is ingested in improper doses or by those with sensitive gastrointestinal tracts. Some users may experience significant abdominal discomfort or an irregular feeling in the stomach shortly after use. Additionally, certain individuals have reported bouts of dizziness that may impair their balance or focus. It is important to monitor these symptoms closely to avoid further complications from the plant's chemical properties.

The main side effects this plant can have are shown in the list below.

  • Nausea
  • Digestive upset
  • Dizziness
Evidence Level: ★☆☆☆☆

What herbs are paired with Atractylodes koreana?

This plant Atractylodes koreanas pairs most effectively with medicinal herbs such as Poria cocos, Atractylodes macrocephala, and Dioscorea opposita to enhance digestive and dampness-regulating functions.

These combinations are frequently utilized in traditional formulations to strengthen the spleen and resolve fluid retention within the body. When paired with Poria cocos, the synergy helps to stabilize the center and promote healthy metabolic processes. Adding Dioscorea opposita can further assist in tonifying the kidneys while supporting the primary effects of the Atractylodes root.

Such botanical alliances are carefully calculated to balance the energetic properties of each ingredient in a formula.

Evidence Level: ★☆☆☆☆