Astragalus ovinus

Astragalus ovinus · Accepted scientific name

Scientific literature: Very Sparse (1 studies) · ★☆☆☆☆

Astragalus ovinus is a botanical species that has garnered significant attention for its diverse therapeutic potential. Recent research highlights its promising anticancer activities, suggesting it may play a role in modulating tumor progression. Additionally, this plant is being investigated for its ability to address various reproductive concerns, including infertility. Scientists often utilize a specialized extract, known as Astragalus ovinus extract (AOE), to concentrate its bioactive compounds. Through these targeted preparations, the plant offers a unique subject for ongoing pharmacological study.

Quick facts
Synonyms
Tragacantha Amana · Astragalus Piestolobus · 12 more
Common names
Not available
Family
Fabaceae
Distribution
Not available
Plant Parts
Not available

Classification

Synonyms

Astragalus ovinus is a taxonomically complex species that is associated with several different botanical names. Within scientific literature, it is recognized as having several synonyms, including the designation Astragalus amanus. This relationship extends to specific variations such as Astragalus angustiflorus subsp. amanus and Astragalus bachtiaricus. Furthermore, the plant is linked to the variety Astragalus bachtiaricus var. leiocarpus. Finally, the name Astragalus faghirensis also serves as a synonym within this interconnected group of botanical classifications.

Sources: The World Checklist of Vascular Plants (WCVP)

Taxonomy

Astragalus ovinus belongs to the vast kingdom Plantae, representing a diverse group of living organisms. Within this kingdom, the species is classified under the class Equisetopsida. It falls specifically into the order Fabales, which helps define its evolutionary lineage. As a member of the family Fabaceae, it shares characteristics with many well-known legumes. Finally, this plant is identified by its specific genus, Astragalus, which characterizes its unique botanical identity.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Fabales
Family Fabaceae
Genus Astragalus

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

Geographic Regions

Astragalus ovinus is a plant species with a notable presence across the temperate regions of Asia. Its geographical range extends significantly throughout Western Asia, where it has established various populations. Specifically, this plant can be found growing within the diverse landscapes of Iran. It also maintains a steady distribution across the territory of Iraq. Furthermore, the species is commonly documented throughout the natural habitats of Türkiye.

Sources: The World Checklist of Vascular Plants (WCVP)

Identification

Biological Activities

Astragalus ovinus has demonstrated significant anticancer potential, particularly in studies involving DMBA-induced breast cancer in rat models. Research indicates that extracts from this plant contain substantial amounts of phenolic and flavonoid compounds, which contribute to its therapeutic effects. These extracts exhibit potent antioxidant activity both in vitro and in vivo, helping to mitigate oxidative damage. Specifically, treatment with the extract has been shown to significantly decrease tumor diameter and volume while reducing key tumorigenicity markers like CA15.3 and p53. Ultimately, the plant shows promising chemopreventive properties by inhibiting tumor growth and reducing histopathological deformities in cancerous tissues.

Compounds

Conditions

Astragalus ovinus demonstrates significant chemopreventive activity against DMBA-induced breast tumors in rat models. The extract of this plant effectively treats DMBA-induced breast carcinoma by reducing tumor diameter and volume. Research also indicates that Astragalus ovinus can treat DMBA-induced breast cancer through its potent antioxidant properties and inhibition of tumorigenicity markers. Regarding reproductive health, the plant is traditionally used in the treatment of infertility. However, specific studies show that while it may impact certain fertility markers, its primary documented medicinal roles in these abstracts relate to its anticancer potential.

Preparations

Astragalus ovinus is prepared as an extract known as AOE to evaluate its potential anticancer properties. This specific extract is utilized in studies to investigate its effects against DMBA-induced breast carcinoma in rat models. The preparation of AOE results in a substance containing significant amounts of phenolic and flavonoid compounds. Researchers administered this AOE orally to assess its ability to reduce tumor volume and diameter. Ultimately, the AOE extract demonstrates potent antioxidant and chemopreventive activities in these experimental settings.

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