Mongolian Milkvetch

Astragalus mongholicus · Accepted scientific name

Scientific literature: Very Extensive (1414 studies) · ★★★★★

Mongolian Milkvetch, scientifically known as Astragalus mongholicus, is a cornerstone of Traditional Chinese Medicine. Renowned for its potent adaptogenic properties, this hardy legume is primarily used to bolster immune function, enhance vitality, and support longevity. It serves as a vital tonic for strengthening the body's protective energy and resilience.

Family
Fabaceae
Native range
Europe
Parts used
Root · Leaf
Common names
Mongolian Milkvetch
Scientific synonyms
Astragalus Propinquus · Phaca Macrostachys · 12 more

Names and Synonyms

Common Names

Scientific Names

Accepted name

Astragalus mongholicus

Synonyms

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant, Astragalus mongholicus, belongs to the kingdom Plantae and the phylum Streptophyta. Within the class Equisetopsida and subclass Magnoliidae, it is classified under the order Fabales and the family Fabaceae. Finally, it is identified by its genus, Astragalus.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Fabales
Family Fabaceae
Genus Astragalus

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a diverse geographical range that spans across both Europe and Asia. In Middle Europe, it can be specifically located within the borders of Germany. Its distribution extends significantly into the vast regions of Siberia. Within Siberia, the species is found in the Altay and Buryatiya territories. Furthermore, it inhabits the Siberian areas of both Chita and Irkutsk.

Region Area
Middle Europe Germany
Siberia Altay
Siberia Buryatiya
Siberia Chita
Siberia Irkutsk
Siberia Krasnoyarsk
Siberia Tuva
Siberia West Siberia
Siberia Yakutiya
Russian Far East Amur

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Ecology

The ecology of Astragalus mongholicus is characterized by its remarkable adaptability to diverse and often rugged landscapes. This species thrives across a wide spectrum of environments, including forests, open meadows, and mountainous terrains, where it can integrate into varying microclimates. It is frequently found in proximity to rivers, where soil moisture levels may be more consistent, as well as within shrubberies and expansive steppe ecosystems. This ability to occupy such varied niches—ranging from the shaded understories of woody vegetation to the exposed, wind-swept conditions of high-altitude mountains and grasslands—demonstrates a highly resilient ecological profile capable of enduring diverse soil compositions and fluctuating climatic conditions.

Habitat :
forest, meadows, mountains, rivers, shrubberies, steppe

Life history

The life history of Astragalus mongholicus is characterized by its nature as a perennial plant, allowing it to establish a stable presence within its natural habitat over multiple growing seasons. As a perennial species, it does not complete its life cycle in a single year like annuals or two years like biennials; instead, it invests significant energy into developing a robust root system that facilitates long-term survival and regrowth. This perennial lifecycle enables the plant to endure seasonal fluctuations and environmental stressors, contributing to its ability to persist in various ecological niches. Through its continuous growth cycles, the plant maintains a steady developmental progression, focusing on both vegetative expansion and periodic reproductive efforts to ensure the continuation of its species across the landscape.

Lifecycle :
perennial

Morphology

The morphology of Astragalus mongholicus is characterized by its growth form as a non-woody herb, specifically classified as a forb or subshrub. This plant is a self-supporting species that does not function as a climber, liana, or vine, and it maintains an independent lifestyle without being a parasite or an epiphyte, typically thriving in terrestrial environments. It is not an aquatic or semiaquatic plant. In terms of stature, it is a relatively low-growing species, with a plant height that ranges from a minimum of 0.25 m to a maximum of 0.85 m.

Aquatic :
terrestrial
Climber :
self-supporting
Epiphyte :
terrestrial
Growth form :
herb
Parasite :
independent
Plant height max:
0.85 m
Plant height min:
0.25 m
Woodiness :
non-woody

Physiology

The physiology of Astragalus mongholicus is primarily characterized by its reliance on a C3 photosynthetic pathway, a trait common among temperate legumes that dictates its carbon fixation processes and metabolic efficiency. Under this C3 mechanism, the plant utilizes the enzyme RuBisCO to fix atmospheric carbon dioxide into three-carbon organic compounds during the Calvin cycle, which is highly effective in the relatively cool, moist environments where it typically thrives. This metabolic framework influences its water-use efficiency and gas exchange patterns, necessitating specific adaptations to manage transpiration rates and avoid photorespiration during periods of thermal stress. Furthermore, its physiological resilience is bolstered by a robust root system capable of efficient nutrient uptake and water transport, supporting the secondary metabolic pathways responsible for synthesizing its characteristic bioactive polysaccharides and saponins.

Photosynthetic pathway :
C3

Reproduction

The reproduction of Astragalus mongholicus is characterized by a specific seasonal flowering window that facilitates its pollination and subsequent seed production. The flowering process typically begins in June and continues through July, though the exact timing can be variable depending on environmental conditions. During this period, the plant produces inflorescences that serve as the primary site for sexual reproduction, attracting necessary pollinators to ensure genetic diversity through seed set.

Flowering time :
Jun
Flowering time :
Jul

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Astragalus mongholicus has 5 reported plant parts identified across 55 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include root, leaf, stem, rhizome, flower.

Plant parts reported in Astragalus mongholicus
Plant part Supporting sources Consensus
Root 41 supporting sources ★★★★★
Leaf 6 supporting sources ★★★☆☆
Stem 5 supporting sources ★★★☆☆
Rhizome 2 supporting sources ★☆☆☆☆
Flower 1 supporting sources ★☆☆☆☆

Root

  1. BMC plant biology
  2. Journal of fungi (Basel, Switzerland)
  3. Journal of AOAC International
  4. Pharmaceutical science advances
  5. Journal of agricultural and food chemistry
View 36 additional sources
  1. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  2. Biochemical and biophysical research communications
  3. Biological trace element research
  4. Botanical studies
  5. International journal of molecular sciences
  6. Cancer letters
  7. Plant biotechnology journal
  8. BMC microbiology
  9. PloS one
  10. Frontiers in plant science
  11. Molecular medicine reports
  12. Acta pharmaceutica Sinica. B
  13. Archives of pharmacal research
  14. Antioxidants (Basel, Switzerland)
  15. International journal of biological macromolecules
  16. Neurochemical research
  17. Acta pharmacologica Sinica
  18. Journal of pharmaceutical analysis
  19. Plant foods for human nutrition (Dordrecht, Netherlands)
  20. Molecules (Basel, Switzerland)
  21. Science China. Life sciences
  22. Nutrients
  23. Journal of natural products
  24. Applied biochemistry and biotechnology
  25. Journal of ethnopharmacology
  26. Plants (Basel, Switzerland)
  27. Plant communications
  28. Frontiers in pharmacology
  29. Fitoterapia
  30. Genes & genomics
  31. Cytokine
  32. Yao xue xue bao = Acta pharmaceutica Sinica
  33. Chinese journal of biotechnology
  34. Zeitschrift fur Naturforschung. C, Journal of biosciences
  35. Plant cell reports
  36. Chemical & pharmaceutical bulletin

Leaf

  1. Pharmaceutical science advances
  2. Bioorganic chemistry
  3. Ultrasonics sonochemistry
  4. Frontiers in plant science
  5. Applied biochemistry and biotechnology
View 1 additional sources
  1. Zeitschrift fur Naturforschung. C, Journal of biosciences

Stem

  1. Pharmaceutical science advances
  2. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  3. Bioorganic chemistry
  4. Ultrasonics sonochemistry
  5. Applied biochemistry and biotechnology

Rhizome

  1. Molecules (Basel, Switzerland)
  2. Acta pharmaceutica Sinica. B

Flower

  1. Molecules (Basel, Switzerland)

Chemicals

Astragalus mongholicus has 235 reported phytochemicals identified across 55 scientific publications and several other databases. The most consistently reported chemicals include Flavonoids, Astragaloside IV, formononetin, Saponins, Calycosin.

Chemicals reported in Astragalus mongholicus
Chemical Supporting sources Consensus
Flavonoids 29 supporting sources ★★★★★
Astragaloside IV 26 supporting sources ★★★★★
formononetin 24 supporting sources ★★★★★
Saponins 23 supporting sources ★★★★★
Calycosin 20 supporting sources ★★★★★
Astragalosides 14 supporting sources ★★★★★
astragaloside 10 supporting sources ★★★★★
Astragalus polysaccharide 8 supporting sources ★★★★☆
Astragaloside III 7 supporting sources ★★★★☆
Astragaloside II 6 supporting sources ★★★☆☆

Flavonoids

  1. Journal of separation science
  2. Food chemistry
  3. Journal of ethnopharmacology
  4. Phytochemical analysis : PCA
  5. BMC microbiology
View 24 additional sources
  1. Metabolites
  2. Frontiers in genetics
  3. Ultrasonics sonochemistry
  4. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  5. Protoplasma
  6. Journal of the American Society for Mass Spectrometry
  7. BMC genomics
  8. PloS one
  9. Molecules (Basel, Switzerland)
  10. Microorganisms
  11. Journal of pharmaceutical analysis
  12. The American journal of Chinese medicine
  13. Plant foods for human nutrition (Dordrecht, Netherlands)
  14. Chinese medicine
  15. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  16. Phytotherapy research : PTR
  17. Nutrients
  18. Talanta
  19. Archives of pharmacal research
  20. Genes & genomics
  21. Toxicology letters
  22. Plants (Basel, Switzerland)
  23. Phytomedicine : international journal of phytotherapy and phytopharmacology
  24. Journal of natural medicines

Astragaloside IV

  1. Dr. Duke
  2. BMC plant biology
  3. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  4. Frontiers in pharmacology
  5. Journal of pharmaceutical and biomedical analysis
View 21 additional sources
  1. International journal of molecular sciences
  2. Planta medica
  3. Biological trace element research
  4. Biochemical and biophysical research communications
  5. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  6. Journal of ethnopharmacology
  7. Metabolites
  8. Signal transduction and targeted therapy
  9. Molecules (Basel, Switzerland)
  10. The Plant journal : for cell and molecular biology
  11. Journal of agricultural and food chemistry
  12. Yao xue xue bao = Acta pharmaceutica Sinica
  13. PloS one
  14. Frontiers in immunology
  15. Angewandte Chemie (International ed. in English)
  16. Phytotherapy research : PTR
  17. Journal of separation science
  18. Biomolecules
  19. Nature plants
  20. Biological procedures online
  21. Journal of cancer research and clinical oncology

formononetin

  1. Dr. Duke
  2. Pharmaceutical science advances
  3. Cancers
  4. International journal of molecular sciences
  5. Biological trace element research
View 19 additional sources
  1. Frontiers in pharmacology
  2. Nutrients
  3. Oncology reports
  4. Frontiers in plant science
  5. Metabolites
  6. Phytomedicine : international journal of phytotherapy and phytopharmacology
  7. Archives of pharmacal research
  8. Journal of agricultural and food chemistry
  9. Molecules (Basel, Switzerland)
  10. Yao xue xue bao = Acta pharmaceutica Sinica
  11. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  12. Evidence-based complementary and alternative medicine : eCAM
  13. Investigational new drugs
  14. Journal of ethnopharmacology
  15. Journal of fungi (Basel, Switzerland)
  16. BioMed research international
  17. Journal of the science of food and agriculture
  18. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  19. Scientific reports

Saponins

  1. Journal of separation science
  2. Food chemistry
  3. Journal of ethnopharmacology
  4. BMC microbiology
  5. Metabolites
View 18 additional sources
  1. Frontiers in pharmacology
  2. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  3. BMC complementary and alternative medicine
  4. Molecules (Basel, Switzerland)
  5. Journal of pharmaceutical analysis
  6. The American journal of Chinese medicine
  7. Chinese medicine
  8. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  9. Phytotherapy research : PTR
  10. Pharmacological research
  11. Nutrients
  12. The Yale journal of biology and medicine
  13. Talanta
  14. Ultrasonics sonochemistry
  15. Archives of pharmacal research
  16. Plants (Basel, Switzerland)
  17. Phytomedicine : international journal of phytotherapy and phytopharmacology
  18. Journal of natural medicines

Calycosin

  1. Dr. Duke
  2. Pharmaceutical science advances
  3. Journal of agricultural and food chemistry
  4. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
  5. International journal of molecular sciences
View 15 additional sources
  1. Biological trace element research
  2. Nutrients
  3. Phytomedicine : international journal of phytotherapy and phytopharmacology
  4. Frontiers in plant science
  5. Journal of ethnopharmacology
  6. Pharmaceutical biology
  7. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  8. Journal of pharmaceutical and biomedical analysis
  9. Molecules (Basel, Switzerland)
  10. Acta pharmacologica Sinica
  11. PloS one
  12. Applied biochemistry and biotechnology
  13. Cancers
  14. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  15. Scientific reports

Astragalosides

  1. Journal of separation science
  2. Current drug targets
  3. International journal of molecular sciences
  4. Plant biotechnology journal
  5. Plant methods
View 9 additional sources
  1. Plants (Basel, Switzerland)
  2. Microorganisms
  3. Molecules (Basel, Switzerland)
  4. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  5. Nature plants
  6. Food chemistry
  7. Talanta
  8. International journal of rheumatic diseases
  9. Plant cell reports

astragaloside

  1. Current vascular pharmacology
  2. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  3. Journal of AOAC International
  4. Molecules (Basel, Switzerland)
  5. Microorganisms
View 5 additional sources
  1. Food & function
  2. Frontiers in pharmacology
  3. Fitoterapia
  4. Journal of the science of food and agriculture
  5. Plant cell reports

Astragalus polysaccharide

  1. Frontiers in oncology
  2. Journal of ethnopharmacology
  3. International journal of biological macromolecules
  4. Carbohydrate polymers
  5. Acta pharmacologica Sinica
View 3 additional sources
  1. Frontiers in nutrition
  2. International journal of molecular medicine
  3. Frontiers in pharmacology

Astragaloside III

  1. Dr. Duke
  2. International journal of molecular sciences
  3. Journal of ethnopharmacology
  4. Phytomedicine : international journal of phytotherapy and phytopharmacology
  5. Angewandte Chemie (International ed. in English)
View 2 additional sources
  1. Molecules (Basel, Switzerland)
  2. Journal of separation science

Astragaloside II

  1. Dr. Duke
  2. Molecules (Basel, Switzerland)
  3. Journal of ethnopharmacology
  4. Phytomedicine : international journal of phytotherapy and phytopharmacology
  5. Journal of separation science
View 1 additional sources
  1. Endocrinology

Activities

Astragalus mongholicus has 585 reported activities identified across 55 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Anticancer, Antitumor, Antiviral, Antidiabetic.

Activities reported in Astragalus mongholicus
Activity Supporting sources Consensus
Antioxidant 18 supporting sources ★★★★★
Anticancer 7 supporting sources ★★★★☆
Antitumor 5 supporting sources ★★★☆☆
Antiviral 5 supporting sources ★★★☆☆
Antidiabetic 4 supporting sources ★★☆☆☆
Cardioprotective 4 supporting sources ★★☆☆☆
Neuroprotective 4 supporting sources ★★☆☆☆
Antibacterial 3 supporting sources ★★☆☆☆
Antidepressant 3 supporting sources ★★☆☆☆
Antimicrobial 3 supporting sources ★★☆☆☆

Antioxidant

  1. Dr. Duke
  2. GigaScience
  3. Cancers
  4. Current drug targets
  5. Journal of food biochemistry
View 13 additional sources
  1. Frontiers in pharmacology
  2. Journal of ethnopharmacology
  3. Antioxidants (Basel, Switzerland)
  4. International journal of biological macromolecules
  5. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  6. Phytotherapy research : PTR
  7. Nutrients
  8. Scientific reports
  9. Ultrasonics sonochemistry
  10. Molecules (Basel, Switzerland)
  11. Genes & genomics
  12. Foods (Basel, Switzerland)
  13. Journal, genetic engineering & biotechnology

Anticancer

  1. Dr. Duke
  2. Cancers
  3. The American journal of Chinese medicine
  4. Phytotherapy research : PTR
  5. Molecules (Basel, Switzerland)
View 2 additional sources
  1. Journal of cancer research and clinical oncology
  2. Journal, genetic engineering & biotechnology

Antitumor

  1. Dr. Duke
  2. Carbohydrate polymers
  3. Ai zheng = Aizheng = Chinese journal of cancer
  4. Journal of ethnopharmacology
  5. International journal of biological macromolecules

Antiviral

  1. Dr. Duke
  2. Anti-inflammatory & anti-allergy agents in medicinal chemistry
  3. International journal of biological macromolecules
  4. Molecules (Basel, Switzerland)
  5. Journal of natural medicines

Antidiabetic

  1. Dr. Duke
  2. Evidence-based complementary and alternative medicine : eCAM
  3. Phytotherapy research : PTR
  4. Molecules (Basel, Switzerland)

Cardioprotective

  1. Dr. Duke
  2. Pharmaceutical science advances
  3. Archives of pharmacal research
  4. Nutrients

Neuroprotective

  1. Dr. Duke
  2. Cancers
  3. BMC complementary and alternative medicine
  4. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

Antibacterial

  1. Dr. Duke
  2. Scientific reports
  3. Molecules (Basel, Switzerland)

Antidepressant

  1. Dr. Duke
  2. Phytomedicine : international journal of phytotherapy and phytopharmacology
  3. Neurochemical research

Antimicrobial

  1. Antioxidants (Basel, Switzerland)
  2. Scientific reports
  3. Journal, genetic engineering & biotechnology

Conditions

Astragalus mongholicus has 18 reported investigations on conditions identified across 55 scientific publications and several other databases. The most consistently reported conditions include aggression, amnesia, anxiety, apoptosis, cancer.

Conditions investigated for Astragalus mongholicus
Condition Supporting sources Consensus
Aggression 1 supporting sources ★☆☆☆☆
Amnesia 1 supporting sources ★☆☆☆☆
Anxiety 1 supporting sources ★☆☆☆☆
Apoptosis 1 supporting sources ★☆☆☆☆
Cancer 1 supporting sources ★☆☆☆☆
Colon cancer 1 supporting sources ★☆☆☆☆
Depression 1 supporting sources ★☆☆☆☆
Drought 1 supporting sources ★☆☆☆☆
Immunosuppression 1 supporting sources ★☆☆☆☆
Infertility 1 supporting sources ★☆☆☆☆

Aggression

  1. Neurochemical research

Amnesia

  1. Neurochemical research

Anxiety

  1. Neurochemical research

Apoptosis

  1. The American journal of Chinese medicine

Cancer

  1. International journal of biological macromolecules

Colon cancer

  1. Frontiers in microbiology

Depression

  1. Neurochemical research

Drought

  1. Environmental microbiology

Immunosuppression

  1. Journal of ethnopharmacology

Infertility

  1. Antioxidants (Basel, Switzerland)

Preparations

Astragalus mongholicus has 89 reported preparations identified across 55 scientific publications and several other databases. The most consistently reported preparations include Astragalus polysaccharides, dried root, extract, extracts, Astragali Radix.

Preparations reported for Astragalus mongholicus
Preparation Supporting sources Consensus
Astragalus polysaccharides 4 supporting sources ★★☆☆☆
Dried root 3 supporting sources ★★☆☆☆
Extract 3 supporting sources ★★☆☆☆
Extracts 3 supporting sources ★★☆☆☆
Astragali radix 2 supporting sources ★☆☆☆☆
Astragalus polysaccharide 2 supporting sources ★☆☆☆☆
Radix astragali 2 supporting sources ★☆☆☆☆
Polysaccharide fractions 2 supporting sources ★☆☆☆☆
Root extract 2 supporting sources ★☆☆☆☆
Roots 2 supporting sources ★☆☆☆☆

Astragalus polysaccharides

  1. Biochemical and biophysical research communications
  2. International journal of biological macromolecules
  3. Journal of neuroimmunology
  4. Chinese medical journal

Dried root

  1. International journal of biological macromolecules
  2. Frontiers in plant science
  3. Molecules (Basel, Switzerland)

Extract

  1. Foods (Basel, Switzerland)
  2. Journal of cancer research and clinical oncology
  3. Antioxidants (Basel, Switzerland)

Extracts

  1. Archives of pharmacal research
  2. Oncology reports
  3. Food science of animal resources

Astragali radix

  1. Frontiers in plant science
  2. Metabolites

Astragalus polysaccharide

  1. Phytotherapy research : PTR
  2. International journal of molecular medicine

Radix astragali

  1. Science China. Life sciences
  2. Frontiers in pharmacology

Polysaccharide fractions

  1. Biochemical and biophysical research communications
  2. Poultry science

Root extract

  1. Neurochemical research
  2. Nutrients

Roots

  1. Plant biotechnology journal
  2. International journal of molecular sciences