Artocarpus nigrifolius
Artocarpus nigrifolius · Accepted scientific name
Scientific literature: Very Sparse (1 studies) · ★☆☆☆☆
Artocarpus nigrifolius is a fascinating botanical species that has garnered increasing interest within the scientific community. Researchers are particularly focused on investigating its unique chemical profile and potential therapeutic benefits. Among its most promising characteristics are its documented antiproliferative activities, which suggest an ability to inhibit rapid cell growth. This specific property makes the plant a significant subject of study in the ongoing search for new medicinal compounds. As studies continue, the plant may play a crucial role in the development of future pharmacological treatments.
- Synonyms
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- Common names
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- Family
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- Distribution
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- Plant Parts
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Classification
Distribution
Geographic Regions
Artocarpus nigrifolius is a botanical species characterized by a specific geographical distribution pattern. This plant is primarily found within the Asia-Temperate regions, showcasing a specialized ecological niche. More specifically, its presence is concentrated within the diverse landscapes of China. Within this country, it is particularly notable in the China South-Central area. Understanding these regional connections is essential for studying the natural habitat of the species.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Artocarpus nigrifolius is a self-supporting tree characterized by its robust and sturdy growth form. This species typically reaches a maximum height of 15 meters as it matures in its natural habitat. Its structural stability allows it to stand firmly within its ecosystem, providing a significant presence in the canopy.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Artocarpus nigrifolius has demonstrated significant potential in pharmacological research due to its notable antiproliferative activity. Recent studies focused on the plant's twigs have successfully isolated several prenylated flavones, including new compounds such as artocarnin A and carpachromenol. When these isolated substances were tested against human cancer cell lines, specifically SiHa and SGC-7901, they exhibited measurable inhibitory effects. One particular compound, eleocharin A, stood out by showing significant cytotoxicity against SiHa cells with a low IC50 value. Consequently, these findings suggest that derivatives from this species could serve as vital lead compounds for the development of new anti-tumor agents.
Compounds
Artocarpus nigrifolius serves as a rich source of diverse prenylated flavones found within its twigs. Recent chemical investigations have successfully isolated several significant compounds from this plant, including the newly identified artocarnin A and carpachromenol. In addition to these new discoveries, the species also contains eleocharin A, a compound noted for its notable biological activity. Research indicates that these specific constituents exhibit antiproliferative effects against various human cancer cell lines. Consequently, these chemical relationships highlight the potential of Artocarpus nigrifolius as a foundation for developing novel anti-tumor agents.