Zi cao
Arnebia euchroma · Accepted scientific name
Scientific literature: Moderate (132 studies) · ★★★☆☆
Zi cao, scientifically known as Arnebia euchroma, is a perennial herb renowned in traditional Chinese medicine for its potent therapeutic properties. Rich in shikonin derivatives, this plant is widely utilized to treat inflammation, skin infections, and promote wound healing, making it a vital component in various dermatological treatments.
- Family
- Boraginaceae
- Native range
- Asia-Temperate
- Parts used
- Root · Leaf
- Common names
- Sinkiang-Tibet Arnebia
- Scientific synonyms
- Macrotomia Euchromon · Lithospermum Euchromon
Names and Synonyms
Common Names
- Sinkiang-Tibet Arnebia
Scientific Names
Accepted name
Arnebia euchromaSynonyms
- Macrotomia euchromon
- Lithospermum euchromon
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and the class Equisetopsida. Within the subclass Magnoliidae, it is placed in the order Boraginales and the family Boraginaceae. Finally, its specific taxonomic identity is defined by the genus Arnebia.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Boraginales |
| Family | Boraginaceae |
| Genus | Arnebia |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant is primarily distributed across the vast landscapes of Central Asia. It can be found growing naturally within the borders of Kazakhstan. Its presence is also documented throughout the mountainous and arid regions of Kirgizstan. Furthermore, the species inhabits various territories in Turkmenistan and Tadzhikistan. Finally, the geographical range of this medicinal herb extends into Uzbekistan.
| Region | Area |
|---|---|
| Central Asia | Kazakhstan |
| Central Asia | Kirgizstan |
| Central Asia | Turkmenistan |
| Central Asia | Tadzhikistan |
| Central Asia | Uzbekistan |
| Western Asia | Afghanistan |
| Western Asia | Iran |
| China | Tibet |
| China | Xinjiang |
| Indian Subcontinent | Nepal |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Ecology
The ecology of Arnebia euchroma is characterized by its adaptation to high-altitude alpine environments, typically thriving in mountainous regions and stony places. This species occupies a specific vertical niche within its ecosystem, with an elevational range spanning from a minimum of 2500 m AMSL to a maximum of 4400 m AMSL. On average, the plant is found at a mean elevation of 3350 m AMSL, where the rugged, rocky terrain provides the necessary substrate for its growth.
- Elevational range max:
- 4400 m AMSL
- Elevational range mean:
- 3350 m AMSL
- Elevational range min:
- 2500 m AMSL
- Habitat :
- mountains, stony places
Life history
The life history of Arnebia euchroma is characterized by its status as a perennial plant, allowing it to persist through multiple growing seasons rather than completing its life cycle in a single year. As a perennial herb, it establishes a robust root system that stores essential nutrients and water, enabling the plant to survive periods of dormancy and emerge repeatedly from the soil. This lifecycle supports a developmental pattern where the plant can invest significant energy into the production of its characteristic deep red or purple pigments and medicinal compounds over several years. Throughout its lifespan, it undergoes seasonal cycles of vegetative growth and flowering, with its ability to endure long-term environmental fluctuations contributing to its stability in its natural habitat.
- Lifecycle :
- perennial
Morphology
The morphology of Arnebia euchroma is characterized by its growth form as a non-woody herb, specifically categorized as a forb. As a terrestrial plant, it does not exhibit aquatic or semiaquatic tendencies, nor does it function as an epiphyte. The species is a self-supporting organism, lacking any climber, liana, or vine-like structures, and it maintains an independent lifestyle without acting as a parasite. Its physical structure is entirely non-woody, reinforcing its classification as a herbaceous plant.
- Aquatic :
- terrestrial
- Climber :
- self-supporting
- Epiphyte :
- terrestrial
- Growth form :
- herb
- Parasite :
- independent
- Woodiness :
- non-woody
Reproduction
The reproduction of Arnebia euchroma is characterized by a specific flowering phenology and the development of small, uniform fruit structures. The flowering period typically begins in June and concludes in July, although the timing can be variable depending on environmental conditions. During the reproductive phase, the plant produces inflorescences that range in length from a minimum of 0.02 m to a maximum of 0.06 m. Following pollination, the plant develops fruits that exhibit highly consistent dimensions; the fruit length is measured at a steady 0.35 cm, with no variation between the minimum, mean, and maximum values. Similarly, the fruit width remains constant at 0.3 cm, with the minimum, mean, and maximum measurements all aligning at this exact value.
- Flowering time :
- Jun
- Flowering time :
- Jul
- Fruit length max:
- 0.35 cm
- Fruit width max:
- 0.3 cm
- Inflorescence length max:
- 0.06 m
- Inflorescence length min:
- 0.02 m
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Arnebia euchroma has 4 reported plant parts identified across 12 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include root, leaf, rhizome, stem.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Root | 9 supporting sources | ★★★★☆ |
| Leaf | 1 supporting sources | ★☆☆☆☆ |
| Rhizome | 1 supporting sources | ★☆☆☆☆ |
| Stem | 1 supporting sources | ★☆☆☆☆ |
Root
- Frontiers in plant science
- Chemical & pharmaceutical bulletin
- Scientific reports
- Journal of ethnopharmacology
- Molecules (Basel, Switzerland)
View 4 additional sources
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Recent patents on biotechnology
- BMC plant biology
- The American journal of Chinese medicine
Leaf
- Molecules (Basel, Switzerland)
Rhizome
- International journal of antimicrobial agents
Stem
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Chemicals
Arnebia euchroma has 39 reported phytochemicals identified across 12 scientific publications and several other databases. The most consistently reported chemicals include shikonin, Acetylshikonin, Flavonoids, Arnebinone, Deoxyshikonin.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| shikonin | 12 supporting sources | ★★★★★ |
| Acetylshikonin | 3 supporting sources | ★★☆☆☆ |
| Flavonoids | 3 supporting sources | ★★☆☆☆ |
| Arnebinone | 2 supporting sources | ★☆☆☆☆ |
| Deoxyshikonin | 2 supporting sources | ★☆☆☆☆ |
| Naphthoquinones | 2 supporting sources | ★☆☆☆☆ |
| 4-Coumaric acid | 1 supporting sources | ★☆☆☆☆ |
| Activated charcoal | 1 supporting sources | ★☆☆☆☆ |
| Alkannin | 1 supporting sources | ★☆☆☆☆ |
| Anthocyanins | 1 supporting sources | ★☆☆☆☆ |
shikonin
- FEMS yeast research
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Scientific reports
- Journal of ethnopharmacology
- Plant physiology and biochemistry : PPB
View 7 additional sources
- Journal of natural products
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Journal of biomolecular screening
- Recent patents on biotechnology
- Applied biochemistry and biotechnology
- Biochimica et biophysica acta
- The American journal of Chinese medicine
Acetylshikonin
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Recent patents on biotechnology
- Biochimica et biophysica acta
Flavonoids
- Frontiers in plant science
- Molecules (Basel, Switzerland)
- BMC plant biology
Arnebinone
- Journal of ethnopharmacology
- Chemical & pharmaceutical bulletin
Deoxyshikonin
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Recent patents on biotechnology
Naphthoquinones
- Molecules (Basel, Switzerland)
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
4-Coumaric acid
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Activated charcoal
- Cell biology international
Alkannin
- Journal of natural products
Anthocyanins
- BMC plant biology
Activities
Arnebia euchroma has 6 reported activities identified across 12 scientific publications and several other databases. The most consistently reported activities include Anticancer, Antimicrobial, Antioxidant, Antiviral, Chemopreventive.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Anticancer | 2 supporting sources | ★☆☆☆☆ |
| Antimicrobial | 2 supporting sources | ★☆☆☆☆ |
| Antioxidant | 2 supporting sources | ★☆☆☆☆ |
| Antiviral | 1 supporting sources | ★☆☆☆☆ |
| Chemopreventive | 1 supporting sources | ★☆☆☆☆ |
| Hepatoprotective | 1 supporting sources | ★☆☆☆☆ |
Anticancer
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Recent patents on biotechnology
Antimicrobial
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Recent patents on biotechnology
Antioxidant
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Recent patents on biotechnology
Antiviral
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Chemopreventive
- Journal of biomolecular screening
Hepatoprotective
- Journal of ethnopharmacology
Medicinal Uses
Arnebia euchroma has 20 reported medicinal uses identified across 12 scientific publications and several other databases. The most consistently reported uses include inflammation, EV-A71, antioxidant, antiviral, cancer.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| inflammation | Pharmaceutics (and other 3 sources) | ★★☆☆☆ |
| EV-A71 | International journal of antimicrobial agents (and other 1 sources) | ★☆☆☆☆ |
| antioxidant | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (and other 1 sources) | ★☆☆☆☆ |
| antiviral | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (and other 1 sources) | ★☆☆☆☆ |
| cancer | Journal of natural products (and other 1 sources) | ★☆☆☆☆ |
| chronic diseases | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| colitis | World journal of gastroenterology (and other 1 sources) | ★☆☆☆☆ |
| dermatitis | Recent patents on biotechnology (and other 1 sources) | ★☆☆☆☆ |
| diarrhea | World journal of gastroenterology (and other 1 sources) | ★☆☆☆☆ |
| eczema | Recent patents on biotechnology (and other 1 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| Arnebia euchroma Oiintment | Iranian Red Crescent medical journal (and other 1 sources) | ★☆☆☆☆ |
| Cell suspension cultures | Applied biochemistry and biotechnology (and other 1 sources) | ★☆☆☆☆ |
| Sephadex column chromatography | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials (and other 1 sources) | ★☆☆☆☆ |
| cell suspension cultures | Cell biology international (and other 1 sources) | ★☆☆☆☆ |
| chloroform extracts | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials (and other 1 sources) | ★☆☆☆☆ |
| distilled water extraction | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials (and other 1 sources) | ★☆☆☆☆ |
| dried root | The American journal of Chinese medicine (and other 1 sources) | ★☆☆☆☆ |
| dried roots | Frontiers in plant science (and other 1 sources) | ★☆☆☆☆ |
| ethanol fractionation | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials (and other 1 sources) | ★☆☆☆☆ |
| extract of Arnebia euchroma | Journal of natural products (and other 1 sources) | ★☆☆☆☆ |